Protective effect of aescin from the seeds of Aesculus hippocastanum on liver injury induced by endotoxin in mice

Phytomedicine

Volumn 18, Issue 14, 2011, Pages 1276-1284

  Jiang, Na ^a   Xin, Wenyu ^a   Wang, Tian ^a   Zhang, Leiming ^a   Fan, Huaying ^a   Du, Yuan ^a   Li, Chong ^a   Fu, Fenghua ^a  

^a YANTAI UNIVERSITY   (China)

Author keywords

11 beta hydroxysteroid dehydrogenase; Aescin; Aesculus hippocastanum; Antioxidative effect; Glucocorticoid receptor; Liver injury; Proinflammatory mediator

Indexed keywords

11BETA HYDROXYSTEROID DEHYDROGENASE 1; 11BETA HYDROXYSTEROID DEHYDROGENASE 2; ALANINE AMINOTRANSFERASE; ASPARTATE AMINOTRANSFERASE; DEXAMETHASONE; ENDOTOXIN; ESCIN; GLUCOCORTICOID RECEPTOR; INTERLEUKIN 1BETA; LIPOPOLYSACCHARIDE; LIVER PROTECTIVE AGENT; NITRIC OXIDE; TUMOR NECROSIS FACTOR ALPHA;

ALANINE AMINOTRANSFERASE BLOOD LEVEL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIOXIDANT ACTIVITY; ARTICLE; ASPARTATE AMINOTRANSFERASE BLOOD LEVEL; CONTROLLED STUDY; CYTOKINE RELEASE; ENDOTOXEMIA; ENZYME ACTIVITY; ENZYME LINKED IMMUNOSORBENT ASSAY; HISTOPATHOLOGY; IMMUNE RESPONSE; INFLAMMATION; LIVER FUNCTION TEST; LIVER INJURY; LIVER PROTECTION; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; WESTERN BLOTTING;

11-BETA-HYDROXYSTEROID DEHYDROGENASE TYPE 1; 11-BETA-HYDROXYSTEROID DEHYDROGENASE TYPE 2; AESCULUS; ALANINE TRANSAMINASE; ANIMALS; ANTIOXIDANTS; ASPARTATE AMINOTRANSFERASES; BLOTTING, WESTERN; CYTOKINES; DEXAMETHASONE; DRUG-INDUCED LIVER INJURY; ESCIN; LIPOPOLYSACCHARIDES; LIVER; MALE; MICE; MOLECULAR STRUCTURE; NITRIC OXIDE; PROTECTIVE AGENTS; SEEDS;

AESCULUS HIPPOCASTANUM; ANIMALIA; MUS;

EID: 80255132957     PISSN: 09447113     EISSN: 1618095X     Source Type: Journal    
DOI: 10.1016/j.phymed.2011.06.011     Document Type: Article

References (45)

1. A.E. Baue, R. Durham, and E. Faist Systemic inflammatory response syndrome (SIRS), multiple organ dysfunction syndrome (MODS), multiple organ failure (MOF): are we winning the battle? Shock 10 1998 79 89 (Pubitemid 128463838)
2. P.J. Barnes, A.P. Greening, and G.K. Crompton Glucocorticoid resistance in asthma Am. J. Respir. Crit. Care Med. 152 1995 125 140
3. M. Beato Gene regulation by steroid hormones Cell 56 1989 335 344 (Pubitemid 19052651)
4. J.S. Beckman, and W.H. Koppenol Nitric oxide, superoxide, and peroxynitrite: the good, the bad, and ugly Am. J. Physiol. 271 1996 1424 1437
5. G.R. Bernard Sepsis trials intersection of investigation, regulation, funding, and practice Am. J. Respir. Crit. Care Med. 152 1995 4 10
6. C.E. Carnovale, C. Scapini, M.L. Alvarez, C. Favre, J. Monti, and M.C. Carrillo Nitric oxide release and enhancement of lipid peroxidation in regenerating rat liver J. Hepatol. 32 2000 798 804 (Pubitemid 30262740)
7. A. Carrillo-Vico, P.J. Lardone, L. Naji, J.M. Fernandez-Santos, I. Martin-Lacave, J.M. Guerrero, and J.R. Calvo Beneficial pleiotropic actions of melatonin in an experimental model of septic shock in mice: regulation of pro-/anti-inflammatory cytokine network, protection against oxidative damage and anti-apoptotic effects J. Pineal Res. 39 2005 400 408
8. J. Cohen The immunopathogenesis of sepsis Nature 420 2002 885 891 (Pubitemid 36019643)
9. J. Crespo, A. Cayón, P. Fernández-Gil, M. Hernández-Guerra, M. Mayorga, A. Domínguez-Díez, J.C. Fernández-Escalante, and F. Pons-Romero Gene expression of tumor necrosis factor alpha and TNF-receptors, p55 and p75, in nonalcoholic steatohepatitis patients Hepatology 34 2001 1158 1163 (Pubitemid 33096588)
10. N.A. Essani, G.M. McGuire, A.M. Manning, and H. Jaeschke Endotoxin-induced activation of the nuclear transcription factor kappa B and. expression of E-selectin messenger RNA in hepatocytes, Kupffer cells, and endothelial cells in vivo J. Immunol. 156 1996 2956 2963 (Pubitemid 126660644)
11. P. Ergang, P. Leden, J. Bryndová, S. Zbánková, I. Miksík, M. Kment, and J. Pácha Glucocorticoid availability in colonic inflammation of rat Dig. Dis. Sci. 53 2008 2160 2167
12. J. Fan, X.Q. Gong, J. Wu, Y.F. Zhang, and R.B. Xu Effect of glucocorticoid receptor (GR) blockade on endotoxemia in rats Circ. Shock 42 1994 76 82 (Pubitemid 24104921)
13. F. Fu, Y. Hou, W. Jiang, R. Wang, and K. Liu Escin: inhibiting inflammation and promoting gastrointestinal transit to attenuate formation of postoperative adhesions World J. Surg. 29 2005 1614 1620 (Pubitemid 41779863)
14. E. Gonzalez-Rey, A. Chorny, G. Robledo, and M. Delgado Cortistatin, a new antiinflammatory peptide with therapeutic effect on lethal endotoxemia J. Exp. Med. 203 2006 563 571
15. K.B. Harikumar, B. Sung, M.K. Pandey, S. Guha, S. Krishnan, and B.B. Aggarwal Escin, a pentacyclic triterpene, chemosensitizes human tumor cells through inhibition of nuclear factor-kappaB signaling pathway Mol. Pharmacol. 77 2010 818 827
16. G.K. Helal Thymoquinone supplementation ameliorates acute endotoxemia-induced liver dysfunction in rats Pak. J. Pharm. Sci. 23 2010 131 137
17. C.H. Ho, S.P. Hsu, C.C. Yang, Y.H. Lee, and C.T. Chien Sialic acid reduces acute endotoxemia-induced liver dysfunction in the rat Shock 32 2009 228 235
18. M.C. Holmes, C.T. Abrahamsen, K.L. French, J.M. Paterson, J.J. Mullins, and J.R. Seckl The mother or the fetus? 11β-hydroxysteroid dehydrogenase type 2 null mice provide evidence for direct fetal programming of behavior by endogenous glucocorticoids J. Neurosci. 26 2006 3840 3844
19. W.M. Hon, K.H. Lee, and H.E. Khoo Nitric oxide in liver diseases: friend, foe, or just passerby? Ann. N.Y. Acad. Sci. 962 2002 275 295 (Pubitemid 34592318)
20. Z.H. Huang, H. Gao, and R.B. Xu Study on glucocorticoid receptors during intestinal ischemia shock and septic shock Circ. Shock 23 1987 27 36 (Pubitemid 18015055)
21. T.B. Issekutz Effects of six different cytokines on lymphocyte adherence to microvascular endothelium and in vivo lymphocyte migration in the rat J. Immunol. 144 1990 2140 2146 (Pubitemid 20106551)
22. D. Johnson, and I. Mayers Multiple organ dysfunction syndrome: a narrative review Can. J. Anaesth. 48 2001 502 509 (Pubitemid 32591256)
23. B. Klosterhalfen, S. Hauptmann, F.A. Offner, B. Amo-Takyi, C. Töns, G. Winkeltau, M. Affify, W. Küpper, C.J. Kirkpatrick, and C. Mittermayer Induction of heat shock protein 70 by zinc-bis-(dl-hydrogenaspartate) reduces cytokine liberation, apoptosis, and mortality rate in a rat model of LD100 endotoxemia Shock 7 1997 254 262 (Pubitemid 127654276)
24. K. Koerber, G. Sass, A.K. Kiemer, A.M. Vollmar, and G. Tiegs In vivo regulation of inducible no synthase in immune-mediated liver injury in mice Hepatology 36 2002 1061 1069 (Pubitemid 35253421)
25. A. Kumar, Y. Takada, and B.B. Aggarwal Nuclear factor-κB: its role in health and disease J. Mol. Med. 82 2004 432 448
26. C. Liu, A. Li, Y.B. Weng, M.L. Duan, B.E. Wang, and S.W. Zhang Changes in intestinal mucosal immune barrier in rats with endotoxemia World J. Gastroenterol. 15 2009 5843 5850
27. S.F. Liu, and A.B. Malik NF-kappa B activation as a pathological mechanism of septic shock and inflammation Am. J. Physiol. Lung Cell Mol. Physiol. 290 2006 622 645
28. E. Marhuenda, C. Alarcón de la Lastra, and M.J. Martín Antisecretory and gastroprotective effects of aescine in rats Gen. Pharmacol. 25 1994 1213 1219 (Pubitemid 24348717)
29. H. Matsuda, Y. Li, and M. Yoshikawa Gastroprotections of escins Ia, Ib IIa, and IIb on ethanol-induced gastric mucosal lesions in rats Eur. J. Pharmacol. 373 1999 63 70 (Pubitemid 29306711)
30. G.U. Meduri, and G.P. Chrousos Duration of glucocorticoid treatment and outcome in sepsis: is the right drug used the wrong way? Chest 114 1998 355 360 (Pubitemid 28387505)
31. G.J. Molijn, J.J. Spek, J.C. van Uffelen, F.H. de Jong, A.O. Brinkmann, H.A. Bruining, S.W. Lamberts, and J.W. Koper Differential adaptation of glucocorticoid sensitivity of peripheral blood mononuclear leukocytes in patients with sepsis or septic shock J. Clin. Endocrinol. Metab. 80 1995 1799 1803
32. M. Montopoli, G. Froldi, M.C. Comelli, M. Prosdocimi, and L. Caparrotta Aescin protection of human vascular endothelial cells exposed to cobalt chloride mimicked hypoxia and inflammatory stimuli Planta Med. 73 2007 285 288 (Pubitemid 46917485)
33. M. Nagai, T. Saigusa, Y. Shimada, H. Inagawa, H. Oshima, and M. Iriki Antibody to tumor necrosis factor (TNF) reduces endotoxin fever Experientia 44 1988 606 607
34. G.O. Osoata, S. Yamamura, M. Ito, C. Vuppusetty, I.M. Adcock, P.J. Barnes, and K. Ito Nitration of distinct tyrosine residues causes inactivation of histone deacetylase Biochem. Biophys. Res. Commun. 384 2009 366 371
35. C.M. Panayiotou, R. Baliga, R. Stidwill, V. Taylor, M. Singer, and A.J. Hobbs Resistance to endotoxic shock in mice lacking natriuretic peptide receptor-A Br. J. Pharmacol. 160 2010 2045 2054
36. H.M. Reichardt, T. Umland, A. Bauer, O. Kretz, and G. Schütz Mice with an increased glucocorticoid receptor gene dosage show enhanced resistance to stress and endotoxic shock Mol. Cell. Biol. 20 2000 9009 9017 (Pubitemid 32245930)
37. S. Rosewicz, A.R. McDonald, B.A. Maddux, I.D. Goldfine, R.L. Miesfeld, and C.D. Logsdon Mechanism of glucocorticoid receptor down-regulation by glucocorticoids J. Biol. Chem. 263 1988 2581 2584 (Pubitemid 18062893)
38. H. Sebai, M. Sani, M.T. Yacoubi, E. Aouani, N. Ghanem-Boughanmi, and M. Ben-Attia Resveratrol, a red wine polyphenol, attenuates lipopolysaccharide- induced oxidative stress in rat liver Ecotoxicol. Environ. Saf. 73 2010 1078 1083
39. F. Senga, L. Yin, H. Karasuno, H. Ohtaki, T. Nakamachi, K. Satoh, and S. Shioda Minus charge stimulation prevents LPS-induced liver injury by reduction of nitric oxide J. Clin. Biochem. Nutr. 42 2008 222 227 (Pubitemid 351913784)
40. L. Shapira, W.A. Soskolne, Y. Houri, V. Barak, A. Halabi, and A. Stabholz Protection against endotoxic shock and lipopolysaccharide-induced local inflammation by tetracycline: correlation with inhibition of cytokine secretion Infect. Immun. 64 1996 825 828 (Pubitemid 26065554)
41. C.R. Sirtori Aescin: pharmacology, pharmacokinetics and therapeutic profile Pharmacol. Res. 44 2001 183 193 (Pubitemid 32889461)
42. G. Szabo, L. Romics Jr., and G. Frendl Liver in sepsis and systemic inflammatory response syndrome Clin. Liver Dis. 6 2002 1045 1066 (Pubitemid 36026462)
43. T. Traeger, M. Mikulcak, C. Eipel, K. Abshagen, S. Diedrich, C.D. Heidecke, S. Maier, and B. Vollmar Kupffer cell depletion reduces hepatic inflammation and apoptosis but decreases survival in abdominal sepsis Eur. J. Gastroenterol. Hepatol. 22 2010 1039 1049
44. S. Ulick, L.S. Levine, P. Gunczler, G. Zanconato, L.C. Ramirez, W. Rauh, A. Rosler, H.L. Bradlow, and M.I. New A syndrome of apparent mineralocorticoid excess associated with defects in the peripheral metabolism of cortisol J. Clin. Endocrinol. Metab. 49 1979 757 764 (Pubitemid 10198311)
45. E.L. van den Akker, J.W. Koper, K. Joosten, F.H. de Jong, J.A. Hazelzet, S.W. Lamberts, and A.C. Hokken-Koelega Glucocorticoid receptor mRNA levels are selectively decreased in neutrophils of children with sepsis Intensive Care Med. 5 2009 1247 1254