The mother or the fetus? 11β-hydroxysteroid dehydrogenase type 2 null mice provide evidence for direct fetal programming of behavior by endogenous glucocorticoids

Journal of Neuroscience

Volumn 26, Issue 14, 2006, Pages 3840-3844

  Holmes, Megan C ^a   Abrahamsen, Christian T ^a   French, Karen L ^a   Paterson, Janice M ^a   Mullins, John J ^a   Seckl, Jonathan R ^a  

^a UNIVERSITY OF EDINBURGH   (United Kingdom)

Author keywords

11 hydroxysteroid dehydrogenase; Anxiety; Behavior; Glucocorticoids; Hypothalamic pituitary adrenal axis; Programming

Indexed keywords

11BETA HYDROXYSTEROID DEHYDROGENASE; 11BETA HYDROXYSTEROID DEHYDROGENASE TYPE 2; DEXAMETHASONE; ENZYME INHIBITOR; GLUCOCORTICOID; PLACENTA ENZYME; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANXIETY; ARTICLE; BEHAVIOR; BIRTH WEIGHT; CONTROLLED STUDY; DISEASE PREDISPOSITION; FEMALE; FETOPLACENTAL UNIT; FETUS; HOMOZYGOSITY; HYPERGLYCEMIA; HYPERTENSION; HYPOTHALAMUS HYPOPHYSIS ADRENAL SYSTEM; LOW BIRTH WEIGHT; MALE; METABOLIC DISORDER; MOOD DISORDER; MOUSE; NONHUMAN; PLACENTA; PREGNANCY; PRENATAL EXPOSURE; PRIORITY JOURNAL; PROGENY; PROTEIN EXPRESSION; PROTEIN FUNCTION; STRESS; ANIMAL; ANIMAL BEHAVIOR; APPARENT MINERALOCORTICOID EXCESS SYNDROME; C57BL MOUSE; ENZYMOLOGY; METABOLISM; MOTHER; PATHOPHYSIOLOGY; PRENATAL DEVELOPMENT;

11-BETA-HYDROXYSTEROID DEHYDROGENASE TYPE 2; ANIMALS; ANXIETY; BEHAVIOR, ANIMAL; BIRTH WEIGHT; FEMALE; FETUS; GLUCOCORTICOIDS; MALE; MICE; MICE, INBRED C57BL; MINERALOCORTICOID EXCESS SYNDROME, APPARENT; MOTHERS; PLACENTA; PREGNANCY;

EID: 33645582847     PISSN: 02706474     EISSN: 02706474     Source Type: Journal    
DOI: 10.1523/JNEUROSCI.4464-05.2006     Document Type: Article

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