Glucocorticoid availability in colonic inflammation of rat

Digestive Diseases and Sciences

Volumn 53, Issue 8, 2008, Pages 2160-2167

  Ergang, P ^a   Leden, P ^a,b   Bryndova J ^a   Zbankova S ^a,b   Miksik I ^a   Kment, M ^b   Pacha J ^a  

^a INSTITUTE OF PHYSIOLOGY   (Czech Republic)

^b CHARLES UNIVERSITY   (Czech Republic)

Author keywords

11 hydroxysteroid dehydrogenase; Inflammation; TNBS colitis

Indexed keywords

11BETA HYDROXYSTEROID DEHYDROGENASE; BUDESONIDE; CARBENOXOLONE; CORTICOSTERONE; CYCLOOXYGENASE 2; GLUCOCORTICOID; INTERLEUKIN 1BETA; MIFEPRISTONE; MUCIN 2; TRINITROBENZENESULFONIC ACID; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; COLITIS; CONTROLLED STUDY; DOWN REGULATION; GENE EXPRESSION; IN VITRO STUDY; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; UPREGULATION;

11-BETA-HYDROXYSTEROID DEHYDROGENASE TYPE 1; 11-BETA-HYDROXYSTEROID DEHYDROGENASE TYPE 2; ANIMALS; BUDESONIDE; CARBENOXOLONE; COLITIS; COLON; CORTICOSTERONE; CYCLOOXYGENASE 2; DISEASE MODELS, ANIMAL; GLUCOCORTICOIDS; HORMONE ANTAGONISTS; INTERLEUKIN-1BETA; MALE; MIFEPRISTONE; MUCINS; PEROXIDASE; RATS; RATS, WISTAR; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; TRINITROBENZENESULFONIC ACID; TUMOR NECROSIS FACTOR-ALPHA;

EID: 46449083838     PISSN: 01632116     EISSN: None     Source Type: Journal    
DOI: 10.1007/s10620-007-0125-6     Document Type: Article

References (44)

1. Besedovsky HO, del Rey A (1996) Immune-neuro-endocrine interactions: facts and hypotheses. Endocr Rev 17:64-102
2. Wilckens T, De Rijk R (1997) Glucocorticoids and immune function: unknown dimensions and new frontier. Immunol Today 18:418-424
3. Stewart PM, Krozowski ZS (1999) 11β-hydroxysteroid dehydrogenase. Vit Horm 57:249-324
4. Tomlinson JW, Walker EA, Bujalska IJ, Draper N, Laverty GG, Cooper MS, Hewison M, Stewart PM (2004) 11β-hydroxysteroid dehydrogenase type 1: a tissue specific regulator of glucocorticoid response. Endocr Rev 25:831-866
5. Escher G, Galli I, Vishwanath BS, Frey BM, Frey FJ (1997) Tumor necrosis factor α and interleukin 1β enhance the corticone/cortisol shuttle. J Exp Med 186:189-198
6. Feinstein MB, Schleimer RP (1999) Regulation of the action of hydrocorticone in airway epithelial cells by 11β-hydroxysteroid dehydrogenase. Am J Respir Cell Mol Biol 21:403-408
7. Suzuki S, Koyama K, Darnel A, Ishibashi H, Kobayashi S, Kubo H, Suzuki T, Sasano H, Krozowski ZS (2003) Dexamethasone upregulates 11β-hydroxysteroid dehydrogenase type 2 in BEAS-2B cells. Am J Respir Crit Care Med 167:1244-1249
8. Suzuki S, Matsuda Y, Sugawara T, Tabata T, Ishibashi H, Hoshikawa Y, Kubo H, Kondo T (2004) Effects of carbenoxolone on alveolar fluid clearance and lung inflammation in the rat. Crit Care Med 32:1910-1915
9. Tomlinson JW, Moore J, Cooper MS, Bujalska I, Shahmanesh M, Burt C, Strain A, Hewison M, Stewart PM (2001) Regulation of expression of 11β-hydroxysteroid dehydrogenase type 1 in adipose tissue: tissue-specific induction by cytokines. Endocrinology 142:1982-1989
10. Heiniger CD, Rochat MK, Frey FJ, Frey BM (2001) TNF-α enhances intracellular glucocorticoid availability. FEBS Lett 507:351-356
11. Cooper MS, Bujalska I, Rabbitt E, Walker EA, Bland R, Sheppard MC, Hewison M, Stewart PM (2001) Modulation of 11β-hydroxysteroid dehydrogenase isozymes by proinflammatory cytokines in osteoblasts: an autocrine switch from glucocorticoid inactivation to activation. J Bone Miner Res 16:1037-1044
12. Yong PYK, Harlow C, Thong CJ, Hillier SG (2002) Regulation of 11β-hydroxysteroid dehydrogenase type 1 gene expression in human ovarian surface epithelial cells by interleukin-1. Human Reprod 9:2300-2306
13. Suzuki S, Tsubochi H, Ishibashi H, Matsuda Y, Suzuki T, Krozowski ZS, Sasano H, Kondo T (2005) Inflammatory mediators down-regulate 11β-hydroxysteroid dehydrogenase type 2 in a human lung epithelial cell line BEAS-2B and rat lung. Tohoku J Exp Med 207:293-301
14. Pácha J, Mikšík I, Lisá V, Pohlová I (1997) Hormonal regulation of intestinal 11β-hydroxysteroid dehydrogenase. Life Sci 61:2391-2396
15. Bryndová J, Žbánková Š, Kment M, Pácha J (2004) Colitis up-regulates local glucocorticoid activation and down-regulates inactivation in colonic tissue. Scand J Gastroenterol 39:549-553
16. Morris GP, Beck PL, Herridge MS, Depew WT, Szewczuk MR, Wallace JL (1989) Hapten-induced model of chronic inflammation and ulceration in the rat colon. Gastroenterology 96:795-803
17. Erdbäcker S, Andersson P, Lindberg C, Paulson J, Ryrfeldt A, Thalen A (1987) Liver metabolism of budesonide in rat, mouse, and man. comparative aspects. Drug Metab Dispos 15:403-411
18. Lyscom N, Brueton MJ (1982) Intraepithelial, lamina propria and peyer's patch lymphocytes of the rat small intestine: isolation and characterization in terms of immunoglobulin markers and receptors for monoclonal antibodies. Immunology 45:775-783
19. Pácha J, Mikšík I (1996) 11β-hydroxysteroid dehydrogenase in developing rat intestine. J Endocrinol 148:561-566
20. Pácha J, Mikšík I, Mrnka L, Zemanová Z, Bryndová J, Mazancová K, Kučka M (2004) Corticosteroid regulation of colonic ion transport during postnatal development: methods for corticosterone analysis. Physiol Res 53:S63-S80
21. Bradley PP, Priebat DA, Christensen RD, Rothstein G (1982) Measurement of cutaneous inflammation: estimation of neutrophil content with an enzyme marker. J Invest Dermatol 78:206-209
22. Zhang TY, Ding X, Daynes RA (2005) The expression of 11β- hydroxysteroid dehydrogenase type I by lymphocytes provides a novel means for intracrine regulation of glucocorticoid activities. J Immunol 174:879-889
23. Rachmilewitz D, Simon PL, Schwartz LW, Griswold DE, Fondacaro JD, Wasserman MA (1989) Inflammatory mediators of experimental colitis in rats. Gastroenterology 97:326-337
24. Neurath MF, Becker C, Barbulescu K (1998) Role of NF-κB in immune and inflammatory responses in the gut. Gut 43:856-860
25. Reed KL, Fruin AB, Gower AC, Gonzales KD, Stucchi AF, Andry CD, O'Brien M, Becker JM (2005) NF-κB activation precedes increases in mRNA encoding neurokinin-1 receptor, proinflammatory cytokines, and adhesion molecules in dextran sulfate sodium-induced colitis in rats. Dig Dis Sci 50:2366-2378
26. Andrianifahanana M, Moniaux N, Batra SK (2006) Regulation of mucin expression: mechanistic aspects and implications for cancer and inflammatory diseases. Biochim Biophys Acta 1765:189-222
27. van der Velden VH (1998) Glucocorticoids: mechanisms of action and anti-inflammatory potential in asthma. Mediators Inflamm 7:229-237
28. Pelissier MA, Muller C, Hill M, Morfin R (2006) Protection against dextran sodium sulfate-induced colitis by dehydroepiandrosterone and 7α-hydroxy-dehydroepiandrosterone in the rat. Steroids 71:240-248
29. Whorwood CB, Ricketts ML, Stewart PM (1994) Epithelial cell localization of type 2 11β-hydroxysteroid dehydrogenase in rat and human colon. Endocrinology 135:2533-2541
30. Thieringer R, Le Grand CB, Carbin L, Cai T-Q, Wong B, Wright SD, Hermanowski-Vosatka A (2001) 11β-hydroxysteroid dehydrogenase type 1 is induced in human monocytes upon differentiation to macrophages. J Immunol 167:30-35
31. Sun K, Myatt L (2003) Enhancement of glucocorticoid-induced 11β-hydroxysteroid dehydrogenase type 1 expression by proinflammatory cytokines in cultured human amnion fibroblasts. Endocrinology 144:5568-5577
32. Hardy DB, Pereria LE, Yang K (1999) Prostaglandins and leukotriene B4 are potent inhibitors of 11β-hydroxysteroid dehydrogenase type 2 activity in human choriocarcinoma JEG-3 cells. Biol Reprod 61:40-45
33. Patel FA, Clifton VL, Chwalisz K, Challis JR (1999) Steroid regulation of prostaglandin dehydrogenase activity and expression in human term placenta and chorio-decidua in relation to labor. J Clin Endocrinol Metab 84:291-299
34. Peskar BM, Holland A, Peskar BA (1976) Effect of carbenoxolone on prostaglandin synthesis and degradation. J Pharm Pharmacol 28:146-148
35. Darnel AD, Archem TK, Yang K (1999) Regulation of 11β-hydroxysteroid dehydrogenase type 2 by steroid hormones and epidermal growth factor in the Ishikawa human endometrial cell line. J Steroid Biochem Mol Biol 70:203-210
36. Goppelt-Struebe M (1997) Molecular mechanisms involved in the regulation of prostaglandin biosynthesis by glucocorticoids. Biochem Pharmacol 53:1389-1395
37. Nakase H, Okazaki K, Tabata Y, Uose S, Ohana M, Uchida K, Nishi T, Debreceni A, Itoh T, Kawanami C, Iwano M, Ikada Y (2001) An oral drug delivery system targeting immune-regulating cells ameliorates mucosal injury in trinitrobenzene sulfonic acid-induced colitis. J Pharmacol Exp Ther 297:1122-1128
38. Smith JW, Castro GA (1978) Relation of peroxidase activity in gut mucosa to inflammation. Am J Physiol 234:R72-R79
39. Palmen MJHJ, Dieleman LA, Soesatyo M, Pena AS, Meuwissen SGM, van Rees EP (1998) Effects of local budesonide treatment on the cell-mediated immune response in acute and relapsing colitis in rats. Dig Dis Sci 43:2518-2525
40. Hoebler C, Gaudier E, De Coppet P, Rival M, Cherbut C (2006) MUC genes are differently expressed during onset and maintenance of inflammation in dextran sodium sulfate-treated mice. Dig Dis Sci 51:381-389
41. Jarry A, Vallette G, Branka JE, Laboisse C (1996) Direct secretory effect of interleukin-1 via type I receptors in human colonic mucous epithelial cells (HT29-C1.16E). Gut 38:240-242
42. Trompette A, Blanchard C, Zoghbi S, Bara J, Claustre J, Jourdan G, Chayvialle JA, Plaisance P (2004) The DHE cell line as a model for studying rat gastro-intestinal mucin expression: effects of dexamethasone. Eur J Cell Biol 83:347-358
43. Yoshimitsu M, Hayamizu K, Egi H, Okiyama J, Okajima M, Itamoto T, Asahara T (2006) The neutrophil/Th1 lymphocyte balance and the therapeutic effect of granulocyte colony-stimulating factor in TNBS-induced colitis of rat strains. J Interferon Cytokine Res 26:291-300
44. Togawa J-I, Nagase H, Tanaka K, Inamori M, Umezawa T, Nakajima A, Naito M, Sato S, Saito T, Sekihara H (2002) Lactoferrin reduces colitis in rats via modulation of the immune system and correction of cytokine inbalance. Am J Physiol 283:G187-G195