Induction of heat shock protein 70 by zinc-bis-(DL- hydrogenaspartate) reduces cytokine liberation, apoptosis, and mortality rate in a rat model of LD100 endotoxemia

Shock

Volumn 7, Issue 4, 1997, Pages 254-262

  Klosterhalfen, Bernd ^a   Hauptmann, Steffen ^a   Offner, Felix Albert ^c   Amo Takyi, Baffour ^a   Töns, Christian ^b   Winkeltau, Gerd ^b   Affify, Mamdouh ^a   Küpper, Werner ^a   Kirkpatrick, Charles James ^d   Mittermayer, Christian ^a  

^a RWTH AACHEN UNIVERSITY   (Germany)

^b UNIVERSITY HOSPITAL RWTH AACHEN   (Germany)

^c UNIVERSITY OF INNSBRUCK   (Austria)

^d JOHANNES GUTENBERG UNIVERSITY   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ASPARTIC ACID; CYTOKINE; DRUG DERIVATIVE; HEAT SHOCK PROTEIN 70; INTERLEUKIN 1; INTERLEUKIN 6; LIPOPOLYSACCHARIDE; ORGANOMETALLIC COMPOUND; TUMOR NECROSIS FACTOR ALPHA; ZINC; ZINC BIS(HYDROGENASPARTATE); ZINC-BIS(HYDROGENASPARTATE);

ANIMAL; APOPTOSIS; ARTICLE; BLOOD; CHEMICALLY INDUCED DISORDER; CHEMISTRY; COMPARATIVE STUDY; DISEASE MODEL; DOSE RESPONSE; DRUG EFFECT; ENDOTOXEMIA; ENZYME LINKED IMMUNOSORBENT ASSAY; IMMUNOHISTOCHEMISTRY; KIDNEY; LIVER; LUNG; MALE; METABOLISM; METHODOLOGY; MICROSCOPY; MORTALITY; PATHOLOGY; RAT; SURVIVAL RATE; WESTERN BLOTTING; WISTAR RAT;

ANIMALS; APOPTOSIS; ASPARTIC ACID; BLOTTING, WESTERN; CYTOKINES; DISEASE MODELS, ANIMAL; DOSE-RESPONSE RELATIONSHIP, DRUG; ENDOTOXEMIA; ENZYME-LINKED IMMUNOSORBENT ASSAY; HSP70 HEAT-SHOCK PROTEINS; IMMUNOHISTOCHEMISTRY; INTERLEUKIN-1; INTERLEUKIN-6; KIDNEY; LIPOPOLYSACCHARIDES; LIVER; LUNG; MALE; MICROSCOPY; ORGANOMETALLIC COMPOUNDS; RATS; RATS, WISTAR; SURVIVAL RATE; TUMOR NECROSIS FACTOR-ALPHA; ZINC;

EID: 0031112021     PISSN: 10732322     EISSN: None     Source Type: Journal    
DOI: 10.1097/00024382-199704000-00003     Document Type: Article

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