Arene- and quinoline-sulfonamides as novel 5-HT 7 receptor ligands

Bioorganic and Medicinal Chemistry

Volumn 19, Issue 22, 2011, Pages 6750-6759

  Zajdel, Paweł ^a   Marciniec, Krzysztof ^b   Maślankiewicz, Andrzej ^b   Paluchowska, Maria H ^c   Satała, Grzegorz ^c   Partyka, Anna ^a   Jastrzbska Wisek, Magdalena ^a   Wróbel, Dagmara ^a   Wesołowska, Anna ^a   Duszyńska, Beata ^c   Bojarski, Andrzej J ^c   Pawłowski, MacIej ^a  

^a JAGIELLONIAN UNIVERSITY MEDICAL COLLEGE   (Poland)

^b MEDICAL UNIVERSITY OF SILESIA   (Poland)

^c INSTITUTE OF PHARMACOLOGY   (Poland)

Author keywords

5 HT 7 receptor antagonist; Arylpiperazines tetrahydroisoquinolines perhydroisoquinolines; Depression; Solid phase synthesis; Sulfonamides

Indexed keywords

3 [2 [2 (4 METHYL 1 PIPERIDINYL)ETHYL] 1 PYRROLIDINESULFONYL]PHENOL; ANTIDEPRESSANT AGENT; ARENESULFONAMIDE DERIVATIVE; N (2 AMINOETHYL) N [3 (1,2,3,4 TETRAHYDROISOQUINOLIN 2 YL)PROPYL]BENZENESULFONAMIDE; N (3 AMINOPROPYL) N [2 (1,2,3,4 TETRAHYDROISOQUINOLIN 2 YL)ETHYL]BENZENESULFONAMIDE; N (3 AMINOPROPYL) N [3 (1,2,3,4 TETRAHYDROISOQUINOLIN 2 YL)PROPYL]BENZENESULFONAMIDE; N (3 AMINOPROPYL) N [4 (1,2,3,4 TETRAHYDROISOQUINOLIN 2 YL)BUTYL]BENZENESULFONAMIDE; N [2 (1,2,3,4 TETRAHYDROISOQUINOLIN 2 YL)ETHYL] 2 NAPHTHALENESULFONAMIDE; N [2 (1,2,3,4 TETRAHYDROISOQUINOLIN 2 YL)ETHYL]BENZENESULFONAMIDE; N [3 (1,2,3,4 TETRAHYDROISOQUINOLIN 2 YL)PROPYL] 2 NAPHTHALENESULFONAMIDE; N [3 (1,2,3,4 TETRAHYDROISOQUINOLIN 2 YL)PROPYL]BENZENESULFONAMIDE; N [3 [4 (2 METHOXYPHENYL)PIPERAZIN 1 YL]PROPYL] 6 QUINOLINESULFONAMIDE; N [3 [4 (2 METHOXYPHENYL)PIPERAZIN 1 YL]PROPYL] 8 QUINOLINESULFONAMIDE; N [4 (1,2,3,4 TETRAHYDROISOQUINOLIN 2 YL)BUTYL] 1 NAPHTHALENESULFONAMIDE; N [4 (1,2,3,4 TETRAHYDROISOQUINOLIN 2 YL)BUTYL] 2 NAPHTHALENESULFONAMIDE; N [4 (1,2,3,4 TETRAHYDROISOQUINOLIN 2 YL)BUTYL]BENZENESULFONAMIDE; N [4 (1,2,3,4 TETRAHYDROISOQUINOLIN 2 YL)BUTYL]QUINOLINESULFONAMIDE; N [4 [4 (2 METHOXYPHENYL)PIPERAZIN 1 YL]BUTYL] 3 QUINOLINESULFONAMIDE; N [4 [4 (2 METHOXYPHENYL)PIPERAZIN 1 YL]BUTYL] 6 QUINOLINESULFONAMIDE; N [4 [4 (2 METHOXYPHENYL)PIPERAZIN 1 YL]BUTYL] 8 QUINOLINESULFONAMIDE; N ETHYL N [4 (1,2,3,4,4A,5,6,7,8,8A DECAHYDROISOQUINOLIN 2 YL)BUTYL] 8 QUINOLINESULFONAMIDE; QUINOLINESULFONAMIDE DERIVATIVE; SEROTONIN 1A RECEPTOR; SEROTONIN 2A RECEPTOR; SEROTONIN 6 RECEPTOR; SEROTONIN 7 RECEPTOR; SEROTONIN ANTAGONIST; SEROTONIN RECEPTOR AFFECTING AGENT; SULFONAMIDE; UNCLASSIFIED DRUG; UNINDEXED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; BINDING AFFINITY; CONFERENCE PAPER; CONTROLLED STUDY; DEPRESSION; DRUG EFFECT; DRUG RECEPTOR BINDING; DRUG SCREENING; DRUG STRUCTURE; DRUG SYNTHESIS; HUMAN; HUMAN CELL; MOUSE; NONHUMAN;

ANIMALS; ANTIDEPRESSIVE AGENTS; BINDING, COMPETITIVE; HUMANS; KINETICS; LIGANDS; LOCOMOTION; MALE; MICE; QUINOLINES; RATS; RECEPTORS, SEROTONIN; STRUCTURE-ACTIVITY RELATIONSHIP; SULFONAMIDES;

MUS;

EID: 80055013420     PISSN: 09680896     EISSN: 14643391     Source Type: Journal    
DOI: 10.1016/j.bmc.2011.09.044     Document Type: Conference Paper

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