-
1
-
-
0036023385
-
Pharmacology of flibanserin
-
Borsini, F.; Evans, K.; Jason, K.; Rohde, F.; Alexander, B.; Pollentier, S. Pharmacology of Flibanserin. CNS Drug Rev. 2002, 8, 117-142. (Pubitemid 34874381)
-
(2002)
CNS Drug Reviews
, vol.8
, Issue.2
, pp. 117-142
-
-
Borsini, F.1
Evans, K.2
Jason, K.3
Rohde, F.4
Alexander, B.5
Pollentier, S.6
-
2
-
-
0041385717
-
1A receptors
-
DOI 10.1038/sj.bjp.0705341
-
Invernizzi, R.W.; Sacchetti, G.; Parini, S.; Acconcia, S.; Samanin, R. Flibanserin, a potential antidepressant drug, lowers 5-HT and raises dopamine and noradrenaline in the rat prefrontal cortex dialysate: Role of 5-HT1A receptors. Br. J. Pharmacol. 2003, 139, 1281-1288. (Pubitemid 37026411)
-
(2003)
British Journal of Pharmacology
, vol.139
, Issue.7
, pp. 1281-1288
-
-
Invernizzi, R.W.1
Sacchetti, G.2
Parini, S.3
Acconcia, S.4
Samanin, R.5
-
3
-
-
70350240118
-
Design of PhaseIII pivotal trials of flibanserin in female Hypoactive Sexual Desire Disorder (HSDD)
-
Jolly, E.; Clayton, A.; Thorp, J.; Lewis-D'Agostini, G. Design of PhaseIII pivotal trials of flibanserin in female Hypoactive Sexual Desire Disorder (HSDD). Sexologies 2008, 17, 133-134.
-
(2008)
Sexologies
, vol.17
, pp. 133-134
-
-
Jolly, E.1
Clayton, A.2
Thorp, J.3
Lewis-D'Agostini, G.4
-
4
-
-
33947216002
-
2A receptor affinity, and in vivo pharmacological evaluation
-
DOI 10.1016/j.bmc.2007.02.018, PII S0968089607001198
-
Zajdel, P.; Subra, G.; Bojarski, A.J.; Duszyńska, B.; Tatarczyńska, E.;Nikiforuk, A.; Chojnicka- Ẃjcik, E.; Pawlowski, M.; Martinez, J. Novel class of arylpiperazines containing N-acylated amino acids: Their synthesis, 5-HT1A, 5-HT2A receptor affinity, and in vivo pharmacological evaluation. Bioorg. Med. Chem. 2007, 15, 2907-2919. (Pubitemid 46420419)
-
(2007)
Bioorganic and Medicinal Chemistry
, vol.15
, Issue.8
, pp. 2907-2919
-
-
Zajdel, P.1
Subra, G.2
Bojarski, A.J.3
Duszynska, B.4
Tatarczynska, E.5
Nikiforuk, A.6
Chojnacka-Wojcik, E.7
Pawlowski, M.8
Martinez, J.9
-
5
-
-
0036225325
-
1A receptors
-
Ĺpez-Rodríguez, M.L.; Ayala, D.; Benhamú, B.; Morcillo, M.J.; Viso, A.Arylpiperazine derivatives acting at 5-HT(1A) receptors. Curr Med. Chem. 2002, 9, 443-469. (Pubitemid 34436758)
-
(2002)
Current Medicinal Chemistry
, vol.9
, Issue.4
, pp. 443-469
-
-
Lopez-Rodriguez, M.L.1
Ayala, D.2
Benhamu, B.3
Morcillo, M.J.4
Viso, A.5
-
6
-
-
52949140574
-
5-HT1A receptor, an old target for new therapeutic agents
-
Lacivita, E.; Leopoldo, M.; Berardi, F.; Perrone, R. 5-HT1A receptor, an old target for new therapeutic agents. Curr Top Med. Chem. 2008, 8, 1024-1034.
-
(2008)
Curr Top Med. Chem.
, vol.8
, pp. 1024-1034
-
-
Lacivita, E.1
Leopoldo, M.2
Berardi, F.3
Perrone, R.4
-
7
-
-
1642374924
-
7Rs) and their ligands
-
DOI 10.2174/0929867043455828
-
Leopoldo, M. Serotonin(7) receptors 5-HT(7)Rs and their ligands. Curr. Med. Chem. 2004, 11, 629-661. (Pubitemid 38380040)
-
(2004)
Current Medicinal Chemistry
, vol.11
, Issue.5
, pp. 629-661
-
-
Leopoldo, M.1
-
8
-
-
60349083385
-
The influence of an ethylene spacer on the 5-HT1A and 5-HT2A receptor affinity of arylpiperazine derivatives of amides with N-acylated amino acids and 3-differently substituted pyrrolidine-2,5-diones
-
Zajdel, P.; Subra, G.; Verdie, P.; Bojarski, A.J.; Duszyńska, B.; Basista, K.; Obniska, J.; Martinez, J.; Pawlowski, M. The influence of an ethylene spacer on the 5-HT1A and 5-HT2A receptor affinity of arylpiperazine derivatives of amides with N-acylated amino acids and 3-differently substituted pyrrolidine-2,5-diones. Eur. J. Med. Chem. 2009, 44, 800-808.
-
(2009)
Eur. J. Med. Chem.
, vol.44
, pp. 800-808
-
-
Zajdel, P.1
Subra, G.2
Verdie, P.3
Bojarski, A.J.4
Duszyńska, B.5
Basista, K.6
Obniska, J.7
Martinez, J.8
Pawlowski, M.9
-
9
-
-
4944233192
-
2A receptors
-
DOI 10.1021/cc049970z
-
Zajdel, P.; Subra, G.; Bojarski, A.J.; Duszyńska, B.; Pawłowski, M.; Martinez, J. A new class of arylpiperazine derivatives: The library synthesison SynPhase lanterns and biological evaluation on serotonin 5-HT1A and 5-HT2A receptors. J. Comb. Chem. 2004, 6, 761-767. (Pubitemid 39329431)
-
(2004)
Journal of Combinatorial Chemistry
, vol.6
, Issue.5
, pp. 761-767
-
-
Zajdel, P.1
Subra, G.2
Bojarski, A.J.3
Duszynska, B.4
Pawlowski, M.5
Martinez, J.6
-
10
-
-
60849083546
-
Distributed Drug Discovery Part 1: Linking academia and combinatorial chemistry to find drug leads for developing world diseases
-
Scott, W.L.; O'Donnell, M.J.; Distributed Drug Discovery, Part 1: Linking academia and combinatorial chemistry to find drug leads for developing world diseases. J. Comb. Chem. 2009, 11, 3-13.
-
(2009)
J. Comb. Chem.
, vol.11
, pp. 3-13
-
-
Scott, W.L.1
O'Donnell, M.J.2
-
11
-
-
60849139415
-
Distributed Drug Discovery Part 2: Global rehearsal of alkylating agents for the synthesis of resin-bound unnatural amino acids and virtual D(3) catalog construction
-
Scott, W.L.; Alsina, J.; Audu, C.O.; Babaev, E.; Cook, L.; Dage, J.L.;Goodwin, L.A.; Martynow, J.G.; Matosiuk, D.; Royo, M.; et al. Distributed Drug Discovery, Part 2: Global rehearsal of alkylating agents for the synthesis of resin-bound unnatural amino acids and virtual D(3) catalog construction. J. Comb. Chem. 2009, 11, 14-33.
-
(2009)
J. Comb. Chem.
, Issue.11
, pp. 14-33
-
-
Scott, W.L.1
Alsina, J.2
Audu, C.O.3
Babaev, E.4
Cook, L.5
Dage, J.L.6
Goodwin, L.A.7
Martynow, J.G.8
Matosiuk, D.9
Royo, M.10
-
12
-
-
60849118108
-
Distributed Drug Discovery, Part 3: Using D( 3) methodology to synthesize analogs of an anti-melanoma compound
-
Scott, W.L.; Audu, C.O.; Dage, J.L.; Goodwin, L.A.; Martynow, J.G.; Platt, L.K.; Smith, J.G.; Strong, A.T.; Wickizer, K.; Woerly, E.M.; et al. Distributed Drug Discovery, Part 3: Using D(3) methodology to synthesize analogs of an anti-melanoma compound. J. Comb. Chem. 2009, 11, 34-43.
-
(2009)
J. Comb. Chem.
, vol.11
, pp. 34-43
-
-
Scott, W.L.1
Audu, C.O.2
Dage, J.L.3
Goodwin, L.A.4
Martynow, J.G.5
Platt, L.K.6
Smith, J.G.7
Strong, A.T.8
Wickizer, K.9
Woerly, E.M.10
-
13
-
-
79957590068
-
-
Available from Leads Metal Products, PO Box 441186, Indianapolis, IN, 46244-1186 (larry@leadsmetal.com)
-
Available from Leads Metal Products, PO Box 441186, Indianapolis, IN, 46244-1186 (larry@leadsmetal.com).
-
-
-
-
14
-
-
0942268107
-
On the Representation of Combinatorial Libraries
-
DOI 10.1021/cc0340325
-
Maclean, D.; Martin, E.J. On the representation of combinatorial libraries. J. Comb. Chem. 2004, 6, 1-11. (Pubitemid 38142631)
-
(2004)
Journal of Combinatorial Chemistry
, vol.6
, Issue.1
, pp. 1-11
-
-
Maclean, D.1
Martin, E.J.2
-
15
-
-
33646947539
-
1A receptor ligands
-
DOI 10.1016/j.bmcl.2006.04.035, PII S0960894X06004306
-
Zajdel, P.; Subra, G.; Bojarski, A.J.; Duszyńska, B.; Pawłowski, M.; Martinez, J. Arylpiperazines with N-acylated amino acids as 5-HT1A receptor ligands. Bioorg. Med. Chem. Lett. 2006, 16, 3406-3410. (Pubitemid 43792526)
-
(2006)
Bioorganic and Medicinal Chemistry Letters
, vol.16
, Issue.13
, pp. 3406-3410
-
-
Zajdel, P.1
Subra, G.2
Bojarski, A.J.3
Duszynska, B.4
Pawlowski, M.5
Martinez, J.6
-
16
-
-
15244347642
-
Parallel solid-phase synthesis and characterization of new sulfonamide and carboxamide proline derivatives as potential CNS agents
-
DOI 10.1016/j.bmc.2005.01.060
-
Zajdel, P.; Subra, G.; Bojarski, A.J.; Duszyńska, B.; Pawłowski, M.; Martinez, J. Parallel solid-phase synthesis and characterization of new sulfonamide and carboxamide proline derivatives as potential CNS agents. Bioorg. Med. Chem. 2005, 13, 3029-3035. (Pubitemid 40387509)
-
(2005)
Bioorganic and Medicinal Chemistry
, vol.13
, Issue.8
, pp. 3029-3035
-
-
Zajdel, P.1
Subra, G.2
Bojarski, A.J.3
Duszynska, B.4
Pawlowski, M.5
Martinez, J.6
-
17
-
-
79957590611
-
-
Available online:(accessed on 26 January 2011)
-
Available online: http://www.mimotopes.com (accessed on 26 January 2011).
-
-
-
-
18
-
-
0027211828
-
2 receptor affinity of some 2- and 3-substituted 1,2,3,4-tetrahydro-β-carbolines
-
Bojarski, A.J.; Cegła, M.T.; Charakchieva-Minol, S.; Mokrosz, M.J.; Maækowiak, M.; Mokrosz, J.L. Structure-activity relationship studies of CNS agents. Part 9: 5-HT1A and 5-HT2 receptor affinity of some 2- and 3-substituted 1,2,3,4-tetrahydro-beta-carbolines. Pharmazie 1993, 48, 289-294. (Pubitemid 23163924)
-
(1993)
Pharmazie
, vol.48
, Issue.4
, pp. 289-294
-
-
Bojarski, A.J.1
Cegla, M.T.2
Charakchieva-Minol, S.3
Mokrosz, M.J.4
Mackowiak, M.5
Misztal, S.6
Mokrosz, J.L.7
|