Sulfonamides with the N-alkyl-N′-dialkylguanidine moiety as 5-HT7 receptor ligands

Bioorganic and Medicinal Chemistry Letters

Volumn 19, Issue 16, 2009, Pages 4827-4831

  Zajdel, Paweł ^a   Subra, Gilles ^b   Verdie, Pascal ^b   Gabzdyl, Ewa ^a   Bojarski, Andrzej J ^c   Duszyńska, Beata ^c   Martinez, Jean ^b   Pawłowski, Maciej ^a  

^a JAGIELLONIAN UNIVERSITY MEDICAL COLLEGE   (Poland)

^b CNRS   (France)

^c INSTITUTE OF PHARMACOLOGY   (Poland)

Author keywords

5 HT1A; 5 HT7 receptor ligands; Arylpiperazines; Guanidines; Serotonin; Solid phase synthesis; Sulfonamides

Indexed keywords

ALKYL GROUP; GUANIDINE DERIVATIVE; LIGAND; PIPERAZINE DERIVATIVE; PIPERIDINE DERIVATIVE; SEROTONIN 1A RECEPTOR; SEROTONIN 2A RECEPTOR; SEROTONIN 7 RECEPTOR; SEROTONIN RECEPTOR AFFECTING AGENT; SULFONAMIDE;

ARTICLE; DEVICE; DRUG RECEPTOR BINDING; DRUG SELECTIVITY; DRUG STRUCTURE; DRUG SYNTHESIS; HUMAN; NONHUMAN; RAT; REACTION ANALYSIS; RECEPTOR AFFINITY; STRUCTURE ANALYSIS;

ANIMALS; GUANIDINES; HUMANS; LIGANDS; RATS; RECEPTOR, SEROTONIN, 5-HT1A; RECEPTOR, SEROTONIN, 5-HT2A; RECEPTORS, SEROTONIN; SEROTONIN 5-HT1 RECEPTOR ANTAGONISTS; SEROTONIN 5-HT2 RECEPTOR ANTAGONISTS; SEROTONIN ANTAGONISTS; STRUCTURE-ACTIVITY RELATIONSHIP; SULFONAMIDES;

EID: 67749139773     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2009.06.038     Document Type: Article

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