1,2,3,4-Tetrahydroisoquinoline derivatives: A new class of 5-HT(1A) receptor ligands

Bioorganic and Medicinal Chemistry

Volumn 7, Issue 2, 1999, Pages 287-295

  Mokrosz, Maria J ^a   Bojarski, Andrzej J ^a   Duszyńska, Beata ^a   Tatarczyńska, Ewa ^b   Kłodzińska, Aleksandra ^b   Dereń Wesołek, Anna ^b   Charakchieva Minol, Sijka ^a   Chojnacka Wójcik, Ewa ^b  

^a Polska Akademia Nauk Oddzial w Krakowie   (Poland)

^b INSTITUTE OF PHARMACOLOGY   (Poland)

Author keywords

5 HT(1A) ligands; Structure activity relationship; Tetrahydroisoquinoline derivatives

Indexed keywords

2 DIPROPYLAMINO 8 HYDROXYTETRALIN; BUSPIRONE; KETANSERIN; RESERPINE; SEROTONIN 1A RECEPTOR; TETRAHYDROISOQUINOLINE DERIVATIVE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BEHAVIOR; BODY TEMPERATURE; CHEMICAL MODIFICATION; DRUG DESIGN; DRUG RECEPTOR BINDING; DRUG SYNTHESIS; INTRAPERITONEAL DRUG ADMINISTRATION; MALE; MOUSE; NONHUMAN; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; RAT; RECEPTOR AFFINITY; SEROTONIN SYNDROME; STRUCTURE ACTIVITY RELATION; SUBCUTANEOUS DRUG ADMINISTRATION;

ADRENERGIC UPTAKE INHIBITORS; ANIMALS; BEHAVIOR, ANIMAL; BODY TEMPERATURE; DOSE-RESPONSE RELATIONSHIP, DRUG; ISOQUINOLINES; KINETICS; LIP; MAGNETIC RESONANCE SPECTROSCOPY; MALE; MICE; MODELS, CHEMICAL; PROTEIN BINDING; RATS; RATS, WISTAR; RECEPTORS, SEROTONIN; RESERPINE; TETRAHYDROISOQUINOLINES;

EID: 0032977866     PISSN: 09680896     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0968-0896(98)00238-7     Document Type: Article

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