Mitochondria impairment correlates with increased sensitivity of aging RPE cells to oxidative stress

Journal of Ocular Biology, Diseases, and Informatics

Volumn 3, Issue 3, 2010, Pages 92-108

  He, Yuan ^a,b,c   Ge, Jian ^b   Burke, Janice M ^d   Myers, Roland L ^a   Dong, Zhi Z ^b   Tombran Tink, Joyce ^a  

^a PENN STATE COLLEGE OF MEDICINE   (United States)

^b SUN YAT SEN UNIVERSITY   (China)

^c Department of Cardiovascular Diseases   (China)

^d MEDICAL COLLEGE OF WISCONSIN   (United States)

Author keywords

Aging; ATP; Mitochondria; Mitochondrial membrane potential; Oxidative stress; RPE cells

Indexed keywords

ADENOSINE TRIPHOSPHATE; CALCIUM; CYTOCHROME C; DICHLORODIHYDROFLUORESCEIN DIACETATE; EXTRACELLULAR SUPEROXIDE DISMUTASE; FLUO 3; HEAT SHOCK PROTEIN 70; LACTATE DEHYDROGENASE; LUCIFERIN; MANGANESE SUPEROXIDE DISMUTASE; PROPIDIUM IODIDE; REACTIVE OXYGEN METABOLITE; UNCOUPLING PROTEIN 2;

ADOLESCENT; ADULT; AGE DISTRIBUTION; AGED; ARTICLE; BIOENERGY; CELL AGING; CHILD; CONTROLLED STUDY; CYTOPLASM; DISORDERS OF MITOCHONDRIAL FUNCTIONS; ELECTRON MICROSCOPY; ENZYME RELEASE; FLOW CYTOMETRY; GENE EXPRESSION; HUMAN; HUMAN CELL; HUMAN TISSUE; MITOCHONDRIAL MEMBRANE POTENTIAL; NUCLEOTIDE SEQUENCE; OXIDATIVE STRESS; PIGMENT EPITHELIUM; PRIORITY JOURNAL; PROTEIN EXPRESSION; REAL TIME POLYMERASE CHAIN REACTION; RETINA MACULA AGE RELATED DEGENERATION; SCHOOL CHILD; SENSITIVITY ANALYSIS;

EID: 80055003440     PISSN: 19368437     EISSN: 19368445     Source Type: Journal    
DOI: 10.1007/s12177-011-9061-y     Document Type: Article

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