Insights into molecular recognition of Lewis X mimics by DC-SIGN using NMR and molecular modelling

Organic and Biomolecular Chemistry

Volumn 9, Issue 22, 2011, Pages 7705-7712

  Guzzi, Cinzia ^a   Angulo, Jesús ^a   Doro, Fabio ^b   Reina, José J ^b   Thépaut, Michel ^c,d,e   Fieschi, Franck ^c,d,f   Bernardi, Anna ^b   Rojo, Javier ^a   Nieto, Pedro M ^a  

^a INSTITUTO DE INVESTIGACIONES QUÍMICAS   (Spain)

^b UNIVERSITY OF MILAN   (Italy)

^c INSTITUT DE BIOLOGIE STRUCTURALE   (France)

^d CNRS   (France)

^e CEA GRENOBLE   (France)

^f INSTITUT UNIVERSITAIRE DE FRANCE   (France)

Author keywords

[No Author keywords available]

Indexed keywords

AROMATIC MOIETIES; BINDING MODES; EQUATORIAL POSITIONS; EXTRACELLULAR DOMAINS; HYDROXYL GROUPS; LEWIS X; MULTI-MODAL;

BINDING ENERGY; MOLECULAR BIOLOGY; MOLECULAR RECOGNITION; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY;

REDUCTION;

CD15 ANTIGEN; CD209 ANTIGEN; CELL ADHESION MOLECULE; CELL SURFACE RECEPTOR; DC-SPECIFIC ICAM-3 GRABBING NONINTEGRIN; FUCOSE; LECTIN; MANNOSE;

ARTICLE; BINDING SITE; BIOMIMETICS; CHEMICAL STRUCTURE; CHEMISTRY; CONFORMATION; DENDRITIC CELL; HUMAN; IMMUNOLOGY; INNATE IMMUNITY; KINETICS; METABOLISM; METHODOLOGY; MOLECULAR GENETICS; MOLECULAR LIBRARY; MOLECULAR MIMICRY; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PROTEIN BINDING; PROTEIN TERTIARY STRUCTURE;

ANTIGENS, CD15; BINDING SITES; BIOMIMETICS; CARBOHYDRATE CONFORMATION; CELL ADHESION MOLECULES; DENDRITIC CELLS; FUCOSE; HUMANS; IMMUNITY, INNATE; KINETICS; LECTINS, C-TYPE; MAGNETIC RESONANCE SPECTROSCOPY; MANNOSE; MODELS, MOLECULAR; MOLECULAR MIMICRY; MOLECULAR SEQUENCE DATA; PROTEIN BINDING; PROTEIN STRUCTURE, TERTIARY; RECEPTORS, CELL SURFACE; SMALL MOLECULE LIBRARIES;

EID: 80054965730     PISSN: 14770520     EISSN: None     Source Type: Journal    
DOI: 10.1039/c1ob05938f     Document Type: Article

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