NMR-Based Characterization of Phenothiazines as a RNA Binding Scaffoldt

Journal of the American Chemical Society

Volumn 126, Issue 13, 2004, Pages 4453-4460

  Mayer, Moriz ^a   James, Thomas L ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DISSOCIATION; MOLECULAR WEIGHT; REACTION KINETICS; RNA; SUBSTITUTION REACTIONS;

BIOAVAILABILITY; LIGANDS;

AROMATIC HYDROCARBONS;

ACETOPROMAZINE; DOUBLE STRANDED RNA; PHENOTHIAZINE DERIVATIVE; PURINE DERIVATIVE; PYRIMIDINE DERIVATIVE; RIBOSOME RNA; RNA; UNCLASSIFIED DRUG;

ARTICLE; BINDING SITE; DISSOCIATION CONSTANT; DRUG BIOAVAILABILITY; HUMAN IMMUNODEFICIENCY VIRUS 1; LIGAND BINDING; MOLECULAR WEIGHT; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; POLIOMYELITIS VIRUS; RNA BINDING; STRUCTURE ACTIVITY RELATION;

BINDING SITES; HIV-1; HUMANS; LIGANDS; MAGNETIC RESONANCE SPECTROSCOPY; NUCLEAR MATRIX; PHENOTHIAZINES; RNA;

EID: 1842450536     PISSN: 00027863     EISSN: None     Source Type: Journal    
DOI: 10.1021/ja0398870     Document Type: Article

References (29)

1. Hermann, T.; Westhof, E. Curr. Opin. Biotechnol. 1998, 9, 66-73.
2. Tor, Y. Chembiochem 2003, 4, 998-1007.
3. Cheng, A. C.; Calabro, V.; Frankel, A. D. Curr. Opin. Struct. Biol. 2001, 11, 478-484.
4. Hwang, S.; Tamilarasu, N.; Ryan, K.; Huq, I.; Richter, S.; Still, W. C.; Rana, T. M. Proc. Natl. Acad. Sci. U.S.A. 1999, 96, 12997-13002.
5. Vicens, Q.; Westhof, E. Chembiochem 2003, 4, 1018-1023.
6. Hermann, T. Biopolymers 2003, 70, 4-18.
7. Mei, H.-Y.; Mack, D. P.; Galan, A. A.; Halim, N. S.; Heldsinger, A.; Loo, J. A.; Moreland, D. W.; Sannes-Lowery, K. A.; Sharmeen, L.; Truong, H. N.; Czamik, A. W. Bioorg. Med. Chem. 1997, 5, 1173-1184.
8. Sannes-Lowery, K. A.; Griffey, R. H.; Hofstadler, S. A. Anal. Biochem. 2000, 280, 264-271.
9. Luedtke, N. W.; Liu, Q.; Tor, Y. Biochemistry 2003, 42, 11391-11403.
10. Lipinski, C. A.; Lombardo, F.; Dominy, B. W.; Feeney, P. J. Adv. Drug Delivery Rev. 2001, 46, 3-26.
11. Carlson, C. B.; Vuyisich, M.; Gooch, B. D.; Beal, P. A. Chem. Biol. 2003, 10, 663-672.
12. Amaral, L.; Kristiansen, J. E. Int. J. Antimicrob. Agents 2001, 18, 411-417.
13. Korth, C.; May, B. C.; Cohen, F. E.; Prusiner, S. B. Proc. Natl. Acad. Sci. U.S.A. 2001, 98, 9836-9841.
14. Mazumder, R.; Ganguly, K.; Dastidar, S. G.; Chakrabarty, A. N. Int. J. Antimicrob. Agents 2001, 18, 403-406.
15. Kristiansen, J. E.; Mortensen, I. Pharmacol. Toxicol. 1987, 60, 100-103.
16. Lind, K. E.; Du, Z.; Fujinaga, K.; Peterlin, B. M.; James, T. L. Chem. Biol. 2002, 9, 185-193.
17. Du, Z.; Lind, K. E.; James, T. L. Chem. Biol. 2002, 9, 707-712.
18. Milligan, J. F.; Uhlenbeck, O. C. In Methods in Enzymology; Dahlberg, J. E., Abelson, J. N., Eds.; Academic Press: New York, 1989; Vol. 180, pp 51-62.
19. Mayer, M.; Meyer, B. J. Am. Chem. Soc. 2001, 123, 6108-6117.
20. Delaglio, F.; Grzesiek, S.; Vuister, G. W.; Zhu, G.; Pfeifer, J.; Bax, A. J. Biomol. NMR 1995, 6, 277-293.
21. Goddard, T. D.; Kneller, D. G. Sparky, 3.0 ed.; University of California: San Francisco, CA, 1998.
22. Fourmy, D.; Recht, M. I.; Blanchard, S. C.; Puglisi, J. D. Science 1996, 274, 1367-1371.
23. Mayer, M.; Meyer, B. Angew. Chem., Int. Ed. 1999, 38, 1784-1788.
24. Mayer, M.; James, T. L. J. Am. Chem. Soc. 2002, 124, 13376-13377.
25. Jayalakshmi, V.; Krishna, N. R. J. Magn. Reson. 2002, 155, 106-118.
26. Yan, J.; Kline, A. D.; Mo, H.; Shapiro, M. J.; Zartler, E. R. J. Magn. Reson. 2003, 163. 270-276.
27. Yu, L.; Oost, T. K.; Schkeryantz, J. M.; Yang, J.; Janowick, D.; Fesik, S. W. J. Am. Chem. Soc. 2003, 125, 4444-4450.
28. Meyer, B.; Weimar, T.; Peters, T. Eur. J. Biochem. 1997, 246, 705-709.
29. Du, Z.; Yu, J.; Andino, R.; James, T. L. Biochemistry 2003, 42, 4373-4383.