Regulation of NMDA receptor subunits after acute ethanol treatment in rat brain

Alcohol and Alcoholism

Volumn 46, Issue 6, 2011, Pages 672-679

  Roh, Myoung Sun ^a,b   Cui, Feng Ji ^b   Kim, Hye Kyeong ^b   Kang, Ung Gu ^a,b  

^a Seoul National University   (South Korea)

^b Seoul National University Hospital   (South Korea)

Author keywords

[No Author keywords available]

Indexed keywords

ALCOHOL; MESSENGER RNA; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; N METHYL DEXTRO ASPARTIC ACID RECEPTOR 1; N METHYL DEXTRO ASPARTIC ACID RECEPTOR 2A; N METHYL DEXTRO ASPARTIC ACID RECEPTOR 2B;

ALCOHOL TOLERANCE; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BRAIN CORTEX; CONTROLLED STUDY; HIPPOCAMPUS; IMMUNOBLOTTING; IN VIVO STUDY; MALE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; RAT; RECEPTOR UPREGULATION; RNA TRANSCRIPTION; SPRAGUE DAWLEY RAT; UBIQUITINATION;

ANIMALS; CENTRAL NERVOUS SYSTEM DEPRESSANTS; CEREBRAL CORTEX; ETHANOL; HIPPOCAMPUS; MALE; PHOSPHORYLATION; PROTEIN SUBUNITS; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, N-METHYL-D-ASPARTATE; RNA, MESSENGER; UBIQUITINATION; UP-REGULATION;

RATTUS;

EID: 80054963786     PISSN: 07350414     EISSN: 14643502     Source Type: Journal    
DOI: 10.1093/alcalc/agr124     Document Type: Article

References (47)

1. Allan AM, Harris RA. (1987) Involvement of neuronal chloride channels in ethanol intoxication, tolerance, and dependence. Recent Dev Alcohol 5:313-25.
2. Bradford MM. (1976) A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal Biochem 72:248-54.
3. Darstein MB, Landwehrmeyer GB, Feuerstein TJ. (2000) Changes in NMDA receptor subunit gene expression in the rat brain following withdrawal from forced long-term ethanol intake. Naunyn Schmiedebergs Arch Pharmacol 361:206-13.
4. Denli AM, Hannon GJ. (2003) RNAi:an ever-growing puzzle. Trends Biochem Sci 28:196-201.
5. Dildy JE, Leslie SW. (1989) Ethanol inhibits NMDA-induced increases in free intracellular Ca2+ in dissociated brain cells. Brain Res 499:383-7.
6. Dingledine R, Borges K, Bowie D et al. (1999) The glutamate receptor ion channels. Pharmacol Rev 51:7-61.
7. Draski LJ, Bice PJ, Deitrich RA. (2001) Developmental alterations of ethanol sensitivity in selectively bred high and low alcohol sensitive rats. Pharmacol Biochem Behav 70:387-96.
8. Floyd DW, Jung KY, McCool BA. (2003) Chronic ethanol ingestion facilitates N-methyl-D-aspartate receptor function and expression in rat lateral/basolateral amygdala neurons. J Pharmacol Exp Ther 307:1020-29.
9. Henniger MS, Wotjak CT, Holter SM. (2003) Long-term voluntary ethanol drinking increases expression of NMDA receptor 2B subunits in rat frontal cortex. Eur J Pharmacol 470:33-6.
10. Hoffman PL, Rabe CS, Moses F et al. (1989) N-methyl-D-aspartate receptors and ethanol:inhibition of calcium flux and cyclic GMP production. J Neurochem 52:1937-40.
11. Hsieh WK, Lin HH, Lai CC. (2009) Involvement of protein kinase C and Src tyrosine kinase in acute tolerance to ethanol inhibition of spinal NMDA-induced pressor responses in rats. Br J Pharmacol 158:806-18.
12. Jin C, Woodward JJ. (2006) Effects of 8 different NR1 splice variants on the ethanol inhibition of recombinant NMDA receptors. Alcohol Clin Exp Res 30:673-9.
13. Jin C, Smothers CT, Woodward JJ. (2008) Enhanced ethanol inhibition of recombinant N-methyl-D-aspartate receptors by magnesium: role of NR3A subunits. Alcohol Clin Exp Res 32:1059-66.
14. Kalluri HS, Mehta AK, Ticku MK. (1998) Up-regulation of NMDA receptor subunits in rat brain following chronic ethanol treatment. Brain Res Mol Brain Res 58:221-4.
15. Kang UG, Koo YJ, Jeon WJ et al. (2006) Activation of extracellular signal-regulated kinase signaling by chronic electroconvulsive shock in the rat frontal cortex. Psychiatry Res 145:75-8.
16. Khanna JM, Kalant H, Le AD et al. (1980) Role of serotonin (5-HT) in drug tolerance and general adaptation. Acta Psychiatr Scand Suppl 286:161-70.
17. Khanna JM, Kalant H, Shah G et al. (1991) Rapid tolerance as an index of chronic tolerance. Pharmacol Biochem Behav 38:427-32.
18. Khanna JM, Kalant H, Weiner J et al. (1992) Ketamine retards chronic but not acute tolerance to ethanol. Pharmacol Biochem Behav 42:347-50.
19. Khanna JM, Morato GS, Kalant H. (2002) Effect of NMDA antagonists, an NMDA agonist, and serotonin depletion on acute tolerance to ethanol. Pharmacol Biochem Behav 72:291-8.
20. Kuner T, Schoepfer R, Korpi ER. (1993) Ethanol inhibits glutamate-induced currents in heteromeric NMDA receptor subtypes. Neuroreport 5:297-300.
21. Leonard AS, Hell JW. (1997) Cyclic AMP-dependent protein kinase and protein kinase C phosphorylate N-methyl-D-aspartate receptors at different sites. J Biol Chem 272:12107-15.
22. Lin HH, Hsieh WK, Shiu JY et al. (2003) Inhibition by ethanol of NMDA-induced responses and acute tolerance to the inhibition in rat sympathetic preganglionic neurons in vitro and in vivo. Br J Pharmacol 140:955-63.
23. Lin HH, Chang SJ, Shie HJ et al. (2006) Ethanol inhibition of NMDA-induced responses and acute tolerance to the inhibition in rat rostral ventrolateral medulla in vivo: involvement of cAMP-dependent protein kinases. Neuropharmacology 51:747-55.
24. Llansola M, Sanchez-Perez A, Cauli O et al. (2005) Modulation of NMDA receptors in the cerebellum. 1. Properties of the NMDA receptor that modulate its function. Cerebellum 4:154-61.
25. Lovinger DM. (1993) Excitotoxicity and alcohol-related brain damage. Alcohol Clin Exp Res 17:19-27.
26. Lovinger DM, White G, Weight FF. (1989) Ethanol inhibits NMDA-activated ion current in hippocampal neurons. Science 243:1721-4.
27. Masood K, Wu C, Brauneis U et al. (1994) Differential ethanol sensitivity of recombinant N-methyl-D-aspartate receptor subunits. Mol Pharmacol 45:324-9.
28. Miranda RC, Pietrzykowski AZ, Tang Y et al. (2010) MicroRNAs: master regulators of ethanol abuse and toxicity? Alcohol Clin Exp Res 34:575-87.
29. Miyakawa T, Yagi T, Kitazawa H et al. (1997) Fyn-kinase as a determinant of ethanol sensitivity:relation to NMDA-receptor function. Science 278:698-701.
30. Nagy J. (2008) Alcohol related changes in regulation of NMDA receptor functions. Curr Neuropharmacol 6:39-54.
31. Nagy J, Kolok S, Boros A et al. (2005) Role of altered structure and function of NMDA receptors in development of alcohol dependence. Curr Neuropharmacol 3:281-97.
32. Qiang M, Denny AD, Ticku MK. (2006) Chronic intermittent ethanol treatment selectively alters N-methyl-D-aspartate receptor subunit surface expression in cultured cortical neurons. Mol Pharmacol 72:95-102.
33. Reynolds JD, Brien JF. (1994) Effects of acute ethanol exposure on glutamate release in the hippocampus of the fetal and adult guinea pig. Alcohol 11:259-67.
34. Roberto M, Bajo M, Crawford E et al. (2006) Chronic ethanol exposure and protracted abstinence alter NMDA receptors in central amygdala. Neuropsychopharmacology 31:988-96.
35. Rosenblum K, Berman DE, Hazvi S et al. (1997) NMDA receptor and the tyrosine phosphorylation of its 2B subunit in taste learning in the rat insular cortex. J Neurosci 17:5129-35.
36. Sanchez-Perez AM, Felipo V. (2005) Serines 890 and 896 of the NMDA receptor subunit NR1 are differentially phosphorylated by protein kinase C isoforms. Neurochem Int 47:84-91.
37. Sathyan P, Golden HB, Miranda RC. (2007) Competing interactions between micro-RNAs determine neural progenitor survival and proliferation after ethanol exposure: evidence from an ex vivo model of the fetal cerebral cortical neuroepithelium. J Neurosci 27:8546-57.
38. Schweizer TA, Vogel-Sprott M. (2008) Alcohol-impaired speed and accuracy of cognitive functions:a review of acute tolerance and recovery of cognitive performance. Exp Clin Psychopharmacol 16:240-50.
39. Snell LD, Nunley KR, Lickteig RL et al. (1996) Regional and subunit specific changes in NMDA receptor mRNA and immunoreactivity in mouse brain following chronic ethanol ingestion. Brain Res Mol Brain Res 40:71-8.
40. Tingley WG, Ehlers MD, Kameyama K et al. (1997) Characterization of protein kinase A and protein kinase C phosphorylation of the N-methyl-D-aspartate receptor NR1 subunit using phosphorylation site-specific antibodies. J Biol Chem 272:5157-66.
41. Trevisan L, Fitzgerald LW, Brose N et al. (1994) Chronic ingestion of ethanol up-regulates NMDAR1 receptor subunit immunoreactivity in rat hippocampus. J Neurochem 62:1635-8.
42. Wang J, Lanfranco MF, Gibb SL et al. (2010) Long-lasting adaptations of the NR2B-containing NMDA receptors in the dorsomedial striatum play a crucial role in alcohol consumption and relapse. J Neurosci 30:10187-98.
43. Wirkner K, Poelchen W, Koles L et al. (1999) Ethanol-induced inhibition of NMDA receptor channels. Neurochem Int 35:153-62.
44. Woodward JJ. (2000) Ethanol and NMDA receptor signaling. Crit Rev Neurobiol 14:69-89.
45. Xu M, Woodward JJ. (2006) Ethanol inhibition of NMDA receptors under conditions of altered protein kinase A activity. J Neurochem 96:1760-67.
46. Xu M, Thetford Smothers C, Woodward JJ. (2011) Effects of ethanol on phosphorylation site mutants of recombinant N-methyl-d-aspartate receptors. Alcohol 45:373-80.
47. Yaka R, Tang KC, Camarini R et al. (2003) Fyn kinase and NR2B-containing NMDA receptors regulate acute ethanol sensitivity but not ethanol intake or conditioned reward. Alcohol Clin Exp Res 27:1736-42.