Phosphorylation of cytosolic phospholipase A2 in platelets is mediated by multiple stress-activated protein kinase pathways

European Journal of Biochemistry

Volumn 265, Issue 1, 1999, Pages 195-203

  Börsch Haubold, Angelika G ^c   Ghomashchi, Farideh ^a   Pasquet, Sophie ^d   Goedert, Michel ^b   Cohen, Philip ^d   Gelb, Michael H ^a   Watson, Steve P ^d  

^a UNIVERSITY OF WASHINGTON   (United States)

^b MRC LABORATORY OF MOLECULAR BIOLOGY   (United Kingdom)

^c JENA UNIVERSITY HOSPITAL   (Germany)

^d NONE

Author keywords

Arachidonic acid; Collagen; Cytosolic phospholipase A2; Platelet; Stress activated protein kinase; Thrombin

Indexed keywords

ARACHIDONIC ACID; MITOGEN ACTIVATED PROTEIN KINASE; MYELIN BASIC PROTEIN; PHOSPHOLIPASE A2; STRESS ACTIVATED PROTEIN KINASE;

ARTICLE; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME PHOSPHORYLATION; PRIORITY JOURNAL; REGULATORY MECHANISM; THROMBOCYTE;

ARACHIDONIC ACID; BLOOD PLATELETS; COLLAGEN; CYTOSOL; ENZYME ACTIVATION; ENZYME INHIBITORS; IMIDAZOLES; MAP KINASE SIGNALING SYSTEM; MITOGEN-ACTIVATED PROTEIN KINASE 12; MITOGEN-ACTIVATED PROTEIN KINASE 13; MITOGEN-ACTIVATED PROTEIN KINASE KINASES; MITOGEN-ACTIVATED PROTEIN KINASES; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PHOSPHOLIPASES A; PLATELET ACTIVATION; PROTEIN ISOFORMS; PYRIDINES; THROMBIN;

TRIXIS;

EID: 0033215384     PISSN: 00142956     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1432-1327.1999.00722.x     Document Type: Article

References (40)

1. 1. Cohen, P. (1997) The search for physiological substrates of MAP and SAP kinases in mammalian cells. Trends Cell Biol. 7, 353-361.
2. 2. Lee, J.C., Laydon, J.T., McDonnell, P.C., Gallagher, T.F., Kumar, S., Green, D., McNulty D., Blumenthal, M.J., Heys, J.R., Landvatter, S.W., Strickler, J.E., McLaughlin, M.M., Siemens, I.R., Fisher, S.M., Livi, G.P., White, J.R., Adams, J.L. & Young, P.R. (1994) A protein kinase involved in the regulation of inflammatory cytokine biosynthesis. Nature 372, 739-746.
3. 3. Han, J., Lee, J.-D., Bibbs, L. & Ulevitch, R.J. (1994) A MAP kinase targeted by endotoxin and hyperosmolarity in mammalian cells. Science 265, 808-811.
4. 4. Freshney, N.W., Rawlinson, L., Guesdon, F., Jones, E., Cowley, S., Hsuan, J. & Saklatvala, J. (1994) Interleukin-α activates a novel protein kinase cascade that result in the phosphorylation of Hsp27. Cell 78, 1039-1049.
5. 5. Rouse, J., Cohen, P., Trigon, S., Morange, M., Alonso-Llamazares, A., Zamanillo, D., Hunt, T. & Nebreda, A.R. (1994) A novel kinase cascade triggered by stress and heat shock that stimulates MAPKAP kinase-2 and phosphorylation of the small heat shock proteins. Cell 78, 1027-1037.
6. 6. Clifton, A.D., Young, P.R. & Cohen, P. (1996) A comparison of the substrate specificity of MAPKAP kinase-2 and MAPKAP kinase-3 and their activation by cytokines and cellular stress. FEBS Lett. 392, 209-214.
7. 7. Waskiewicz, A.J., Flynn, A., Proud, C.G. & Cooper, J.A. (1997) Mitogen-activated protein kinases activate the serine/threonine kinases Mnk1 and Mnk2. EMBO J. 16, 1909-1920.
8. 8. Fukunaga, R. & Hunter, T. (1997) MNK1, a new MAP kinase-activated protein kinase, isolated by a novel expression screening method for identifying protein kinase substrates. EMBO J. 16, 1921-1933.
9. 9. Deak, M., Clifton, A.D., Lucocq, J.M. & Alessi, D.R. (1998) Mitogen-and stress-activated protein kinase-1 (MSK1) is directly activated by MAPK and SAPK2/p38, and may mediate activation of CREB. EMBO J. 17, 4426-4441.
10. 10. New, L., Jiang, Y., Zhao, M., Liu, K., Zhu, W., Flood, L.J., Kato, Y., Parry, G.C.N. & Han, J. (1998) PRAK, a novel protein kinase regulated by the p38 MAP kinase. EMBO J. 17, 3372-3384.
11. 11. Jiang, Y., Chen, C., Li, Z., Guo, W., Gegner, J.A., Lin, S. & Han, J. (1996) Characterization of the structure and function of a new mitogen-activated protein kinase (p38β). J. Biol. Chem. 271, 17920-17926.
12. 12. Li, Z., Jiang, Y., Ulevitch, R.J. & Han, J. (1996) The primary structure of p38γ: a new member of p38 group of MAP kinases. Biochem. Biophys. Res. Commun. 228, 334-340.
13. 13. Mertens, S., Craxton, M. & Goedert, M. (1996) SAP kinase-3, a new member of the family of mammalian stress-activated protein kinases. FEBS Lett. 383, 273-276.
14. 14. Cuenda, A., Cohen, P., Buèe-Scherrer, V. & Goedert, M. (1997) Activation of stress-activated protein kinase-3 (SAPK3) by cytokines and cellular stresses is mediated via SAPKK3 (MKK6); comparison of the specificities of SAPK3 and SAPK2 (RK/p38). EMBO J. 16, 295-305.
15. 15. Wang, X.S., Diener, K., Manthey, C.L., Wang, S., Rosenzweig, B., Bray, J., Delaney, J., Cole, C.N., Chan-Hui, P.-Y., Mantlo, N., Lichenstein, H.S., Zukowski, M. & Zhengbin, Y. (1997) Molecular cloning and characterization of a novel p38 mitogen-activated protein kinase. J. Biol. Chem. 272, 23668-23674.
16. 16. Goedert, M., Cuenda, A., Craxton, M., Jakes, R. & Cohen, P. (1997) Activation of the novel stress-activated protein kinase SAPK4 by cytokines and cellular stresses is mediated by SKK3 (MKK6); comparison of its substrate specificity with that of other SAP kinases. EMBO J. 16, 3563-3571.
17. 2). FEBS Lett. 410, 49-53.
18. 2 is phosphorylated and activated by MAP kinase. Cell 72, 269-278.
19. 2 by p42 microtubule-associated protein 2 kinase and protein kinase C. J. Biol. Chem. 268, 1960-1964.
20. 2 expressed in insect cells and present in human monocytes. J. Biol. Chem. 271, 6987-6997.
21. 2 in agonist-stimulated human platelets and HeLa cells. J. Biol. Chem. 273, 4449-4458.
22. 2. In Signal-Activated Phospholipases (Liscovitch, M., ed.), pp. 13-30. R.G. Landes Co., Austin, TX, USA.
23. 2. J. Biol. Chem. 272, 16709-16712.
24. 2. J. Biol. Chem. 271, 27723-27729.
25. 2 are abrogated by an inhibitor of the p38 mitogen-activated proline kinase cascade in human neutrophilis. Biochem. J. 319, 17-20.
26. 2 by 38-kDa mitogen-activated protein kinase in collagen-stimulated human platelets. Eur. J. Biochem. 245, 751-759.
27. 2 to the nuclear envelope and endoplasmatic reticulum. J. Biol. Chem. 270, 30749-30754.
28. 2 from cytosol to the nuclear envelope in rat basophilic leukemia cells stimulated with calcium ionophore or IgE/antigen. J. Biol. Chem. 270, 15359-15367.
29. 2+-dependent translocation domain with homology to PKC and GAP. Cell 65, 1043-1051.
30. 2+-independent catalytic domain. J. Biol. Chem. 269, 18239-18249.
31. 2. J. Biol. Chem. 273, 1596-1604.
32. 2. Biochemistry 37, 8516-8526.
33. 33. Raingeaud, J., Gupta, S., Rogers, J.S., Dickens, M., Han, J., Ulevitch, R.J. & Davis, R.J. (1995) Pro-inflammatory cytokines and environmental stress cause p38 mitogen-activated protein kinase activation by dual phosphorylation on tyrosine and threonine. J. Biol. Chem. 270, 7420-7426.
34. 2 by thrombin and thrombin receptor agonist peptide in human platelets. J. Biol. Chem. 270, 14816-14823.
35. 2 on anionic vesicles in the scooting mode. Biochemistry 36, 3216-3231.
36. 2 is phosphorylated in collagen-and thrombin-stimulated human platelets independent of protein kinase C and mitogen-activated protein kinase. J. Biol. Chem. 270, 25885-25892.
37. 2 in human platelets. J. Biol. Chem. 268, 26796-26804.
38. 2. Biochem. J. 318, 207-212.
39. 39. Kramer, R.M., Roberts, E.F., Strifler, B.A. & Johnstone, E.M. (1995) Thrombin induces activation of p38 MAP kinase in human platelets. J. Biol. Chem. 270, 27395-27398.
40. 2 in regulating arachidonic acid release in macrophages. J. Biol. Chem. 273, 8203-8211.