Mitochondrial 12S rRNA mutations associated with aminoglycoside ototoxicity

Mitochondrion

Volumn 11, Issue 2, 2011, Pages 237-245

  Guan, Min Xin ^a,b,c  

^a CINCINNATI CHILDREN'S HOSPITAL MEDICAL CENTER   (United States)

^b UNIVERSITY OF CINCINNATI COLLEGE OF MEDICINE   (United States)

^c WENZHOU MEDICAL UNIVERSITY   (China)

Author keywords

Aminoglycoside ototoxicity; Deafness; Haplogroup; Mitochondrial 12S rRNA; Modifier genes; Molecular epidemiology; Mutation; Prevention; Variants

Indexed keywords

AMINOGLYCOSIDE ANTIBIOTIC AGENT; MITOCHONDRIAL RNA; RNA 12S;

ANTIBIOTIC THERAPY; BASE PAIRING; BINDING SITE; BIOCHEMISTRY; CELL RESPIRATION; CLINICAL FEATURE; DISEASE SEVERITY; DRUG SAFETY; GENE IDENTIFICATION; GENE MUTATION; HAPLOTYPE; HEARING IMPAIRMENT; HEARING LOSS; HUMAN; MITOCHONDRIAL GENE; MOLECULAR EPIDEMIOLOGY; ONSET AGE; OTOTOXICITY; PENETRANCE; PHENOTYPE; PRIORITY JOURNAL; PROTEIN SYNTHESIS; REVIEW;

AMINOGLYCOSIDES; CARBOHYDRATE SEQUENCE; HEARING LOSS; HUMANS; MITOCHONDRIA; MOLECULAR EPIDEMIOLOGY; MOLECULAR SEQUENCE DATA; MUTATION; RNA, RIBOSOMAL;

EID: 79251600222     PISSN: 15677249     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.mito.2010.10.006     Document Type: Review

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