Enhanced bioavailability after oral and pulmonary administration of baicalein nanocrystal

International Journal of Pharmaceutics

Volumn 420, Issue 1, 2011, Pages 180-188

  Zhang, Jianjun ^a   Lv, Huixia ^a   Jiang, Kun ^a   Gao, Yuan ^a  

^a CHINA PHARMACEUTICAL UNIVERSITY   (China)

Author keywords

Anti solvent recrystallization; Baicalein; Bioavailability; High pressure homogenization; Nanocrystal; Pulmonary administration

Indexed keywords

BAICALEIN; NANOCRYSTAL;

ANIMAL EXPERIMENT; ARTICLE; CRYSTALLIZATION; DIFFERENTIAL SCANNING CALORIMETRY; DRUG ABSORPTION; DRUG BIOAVAILABILITY; DRUG DELIVERY SYSTEM; DRUG DETERMINATION; DRUG DISTRIBUTION; DRUG SOLUBILITY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; IN VITRO STUDY; IN VIVO STUDY; MALE; NONHUMAN; PARTICLE SIZE; PLASMA CONCENTRATION-TIME CURVE; PRIORITY JOURNAL; RAT; SCANNING ELECTRON MICROSCOPY; SCUTELLARIA BAICALENSIS; TIME TO MAXIMUM PLASMA CONCENTRATION; X RAY POWDER DIFFRACTION; ZETA POTENTIAL;

ABSORPTION; ADMINISTRATION, INHALATION; ADMINISTRATION, ORAL; ANIMALS; BIOLOGICAL AVAILABILITY; CALORIMETRY, DIFFERENTIAL SCANNING; CHEMISTRY, PHARMACEUTICAL; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; CRYSTALLOGRAPHY, X-RAY; DRUGS, CHINESE HERBAL; EXCIPIENTS; FLAVANONES; INJECTIONS, INTRAVENOUS; MALE; MICROSCOPY, ELECTRON, SCANNING; NANOPARTICLES; NANOTECHNOLOGY; PARTICLE SIZE; POWDER DIFFRACTION; RATS; RATS, SPRAGUE-DAWLEY; SOLUBILITY; SOLVENTS; SURFACE PROPERTIES; TECHNOLOGY, PHARMACEUTICAL;

EID: 80054701884     PISSN: 03785173     EISSN: 18733476     Source Type: Journal    
DOI: 10.1016/j.ijpharm.2011.08.023     Document Type: Article

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