Hypoglycemic efficacy of pulmonary delivered insulin dry powder aerosol in rats

Acta Pharmacologica Sinica

Volumn 23, Issue 5, 2002, Pages 467-470

  Chen, Xi Jing ^a   Zhu, Jia Bi ^a   Wang, Guang Ji ^a   Zhou, Ming Xia ^a   Xin, Fu Meng ^a   Zhang, Na ^a   Wang, Cheng Xi ^a   Xu, Yue Ning ^a  

^a CHINA PHARMACEUTICAL UNIVERSITY   (China)

Author keywords

Aerosols; Biological availability; Hypoglycemic agents; Insulin

Indexed keywords

GLUCOSE; INSULIN; ANTIDIABETIC AGENT;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DOSE RESPONSE; DRUG ABSORPTION; DRUG DELIVERY SYSTEM; DRUG EFFECT; DRUG EFFICACY; DRUG FORMULATION; DRY POWDER; EVALUATION; GLUCOSE BLOOD LEVEL; MALE; NONHUMAN; RAT; ANIMAL; INHALATIONAL DRUG ADMINISTRATION; METABOLISM; POWDER; SPRAGUE DAWLEY RAT;

ADMINISTRATION, INHALATION; ANIMALS; BLOOD GLUCOSE; HYPOGLYCEMIC AGENTS; INSULIN; MALE; POWDERS; RATS; RATS, SPRAGUE-DAWLEY;

EID: 0036247176     PISSN: 16714083     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (9)

1. Determinants of drug and polypeptide bioavailability from aerosols delivered to the lung
2. Drug delivery takes a deep breath
3. Pulmonary delivery of drugs for bone disorders
4. Intratracheal delivery of peptide and protein agents: Absorption from solution and dry powder by rat lung
5. Inhaled insulin approaching market
6. Pulmonary delivery of free and liposomal insulin
7. Proteolytic enzymes as a limitation for pulmonary absorption of insulin: In vitro and in vivo investigations
8. Oral administration of insulin in solid form to nondiabetic and diabetic dogs
9. Targeted eternal delivery of insulin to rats