메뉴 건너뛰기




Volumn 11, Issue 9, 2011, Pages 904-910

Ceramide transfer protein and cancer

Author keywords

Cancer; Ceramide; Ceramide transfer protein; Shingolipids

Indexed keywords

CERAMIDE; CERAMIDE 1 PHOSPHATE; CERAMIDE TRANSFER PROTEIN; CISPLATIN; CYCLOPHOSPHAMIDE; DOXORUBICIN; FLUOROURACIL; LIPID TRANSFER PROTEIN; PACLITAXEL; SPHINGOLIPID; SPHINGOSINE 1 PHOSPHATE; UNCLASSIFIED DRUG;

EID: 80054061400     PISSN: 18715206     EISSN: 18755992     Source Type: Journal    
DOI: 10.2174/187152011797655087     Document Type: Review
Times cited : (11)

References (68)
  • 1
    • 13244255551 scopus 로고    scopus 로고
    • Enzymes of sphingolipid metabolism in Drosophila melanogaster
    • Acharya, U.; Acharya, J.K., Enzymes of sphingolipid metabolism in Drosophila melanogaster. Cell Mol Life Sci, 2005, 62, (2), 128-142
    • (2005) Cell Mol Life Sci , vol.62 , Issue.2 , pp. 128-142
    • Acharya, U.1    Acharya, J.K.2
  • 2
    • 38549152194 scopus 로고    scopus 로고
    • Principles of bioactive lipid signalling: Lessons from sphingolipids
    • Hannun, Y.A.; Obeid, L.M., Principles of bioactive lipid signalling: lessons from sphingolipids. Nat Rev Mol Cell Biol, 2008, 9, (2), 139-150
    • (2008) Nat Rev Mol Cell Biol , vol.9 , Issue.2 , pp. 139-150
    • Hannun, Y.A.1    Obeid, L.M.2
  • 3
    • 78049507803 scopus 로고    scopus 로고
    • Gangliosides as regulators of cell membrane organization and functions
    • Sonnino, S.; Prinetti, A., Gangliosides as regulators of cell membrane organization and functions. Adv Exp Med Biol, 2010, 688, 165-184
    • (2010) Adv Exp Med Biol , vol.688 , pp. 165-184
    • Sonnino, S.1    Prinetti, A.2
  • 4
    • 27844517355 scopus 로고    scopus 로고
    • Sphingosine 1-phosphate and ceramide 1-phosphate: Expanding roles in cell signaling
    • Chalfant, C.E.; Spiegel, S., Sphingosine 1-phosphate and ceramide 1-phosphate: expanding roles in cell signaling. J Cell Sci, 2005, 118, (Pt 20), 4605-4612
    • (2005) J Cell Sci , vol.118 , Issue.Pt 20 , pp. 4605-4612
    • Chalfant, C.E.1    Spiegel, S.2
  • 5
    • 77956394811 scopus 로고    scopus 로고
    • A lipid matrix model of membrane raft structure
    • Quinn, P.J., A lipid matrix model of membrane raft structure. Progress in lipid research, 2010, 49, (4), 390-406
    • (2010) Progress In Lipid Research , vol.49 , Issue.4 , pp. 390-406
    • Quinn, P.J.1
  • 8
    • 27644537134 scopus 로고    scopus 로고
    • Serine palmitoyl-CoA transferase (SPT) deficiency and sphingolipid levels in mice
    • Hojjati, M.R.; Li, Z.; Jiang, X.-C., Serine palmitoyl-CoA transferase (SPT) deficiency and sphingolipid levels in mice. Biochimica et biophysica acta, 2005, 1737, (1), 44-51
    • (2005) Biochimica Et Biophysica Acta , vol.1737 , Issue.1 , pp. 44-51
    • Hojjati, M.R.1    Li, Z.2    Jiang, X.-C.3
  • 10
    • 78649373124 scopus 로고    scopus 로고
    • Membranes in balance: Mechanisms of sphingolipid homeostasis
    • Breslow, D.K.; Weissman, J.S., Membranes in balance: mechanisms of sphingolipid homeostasis. Molecular cell, 2010, 40, (2), 267-279
    • (2010) Molecular Cell , vol.40 , Issue.2 , pp. 267-279
    • Breslow, D.K.1    Weissman, J.S.2
  • 11
    • 0035842889 scopus 로고    scopus 로고
    • Vesicular and nonvesicular transport of ceramide from ER to the Golgi apparatus in yeast
    • Funato, K.; Riezman, H., Vesicular and nonvesicular transport of ceramide from ER to the Golgi apparatus in yeast. J Cell Biol, 2001, 155, (6), 949-959
    • (2001) J Cell Biol , vol.155 , Issue.6 , pp. 949-959
    • Funato, K.1    Riezman, H.2
  • 12
    • 0026465549 scopus 로고
    • Sphingolipid transport in mitotic HeLa cells
    • Collins, R.N.; Warren, G., Sphingolipid transport in mitotic HeLa cells. J Biol Chem, 1992, 267, (34), 24906-24911
    • (1992) J Biol Chem , vol.267 , Issue.34 , pp. 24906-24911
    • Collins, R.N.1    Warren, G.2
  • 13
    • 0032143958 scopus 로고    scopus 로고
    • Ceramide transport from endoplasmic reticulum to Golgi apparatus is not vesicle-mediated
    • Kok, J.W.; Babia, T.; Klappe, K.; Egea, G.; Hoekstra, D., Ceramide transport from endoplasmic reticulum to Golgi apparatus is not vesicle-mediated. Biochem J, 1998, 333 (Pt 3), 779-786
    • (1998) Biochem J , vol.333 , Issue.Pt 3 , pp. 779-786
    • Kok, J.W.1    Babia, T.2    Klappe, K.3    Egea, G.4    Hoekstra, D.5
  • 14
    • 0027447066 scopus 로고
    • Ceramide excluded from cell-free vesicular lipid transfer from endoplasmic reticulum to Golgi apparatus. Evidence for lipid sorting
    • Moreau, P.; Cassagne, C.; Keenan, T.W.; Morre, D.J., Ceramide excluded from cell-free vesicular lipid transfer from endoplasmic reticulum to Golgi apparatus. Evidence for lipid sorting. Biochim Biophys Acta, 1993, 1146, (1), 9-16
    • (1993) Biochim Biophys Acta , vol.1146 , Issue.1 , pp. 9-16
    • Moreau, P.1    Cassagne, C.2    Keenan, T.W.3    Morre, D.J.4
  • 17
    • 0036517315 scopus 로고    scopus 로고
    • Teaching students to care for and about people with disabilities
    • Wilson, J.S.; Merrill, A.S., Teaching students to care for and about people with disabilities. Nurse Educ, 2002, 27, (2), 89-93
    • (2002) Nurse Educ , vol.27 , Issue.2 , pp. 89-93
    • Wilson, J.S.1    Merrill, A.S.2
  • 18
    • 0033947176 scopus 로고    scopus 로고
    • Sphingolipids
    • Shayman, J.A., Sphingolipids. Kidney Int, 2000, 58, (1), 11-26
    • (2000) Kidney Int , vol.58 , Issue.1 , pp. 11-26
    • Shayman, J.A.1
  • 19
    • 0037071871 scopus 로고    scopus 로고
    • Sphingolipid functions in Saccharomyces cerevisiae
    • Dickson, R.C.; Lester, R.L., Sphingolipid functions in Saccharomyces cerevisiae. Biochim Biophys Acta, 2002, 1583, (1), 13-25
    • (2002) Biochim Biophys Acta , vol.1583 , Issue.1 , pp. 13-25
    • Dickson, R.C.1    Lester, R.L.2
  • 20
    • 0014694821 scopus 로고
    • The occurrence of tetradecasphing-4-enine and hexadecasphing-4-enine as the principal sphingosines of Musca domestica larvae and adults
    • Bieber, L.L.; O'Connor, J.D.; Sweeley, C.C., The occurrence of tetradecasphing-4-enine and hexadecasphing-4-enine as the principal sphingosines of Musca domestica larvae and adults. Biochim Biophys Acta, 1969, 187, (1), 157-159
    • (1969) Biochim Biophys Acta , vol.187 , Issue.1 , pp. 157-159
    • Bieber, L.L.1    O'Connor, J.D.2    Sweeley, C.C.3
  • 21
    • 0015087107 scopus 로고
    • Metabolism of ceramide phosphorylethanolamine, phosphatidylinositol, phosphatidylserine and phosphatidylglycerol by housefly larvae
    • Hildenbrandt, G.R.; Abraham, T.; Bieber, L.L., Metabolism of ceramide phosphorylethanolamine, phosphatidylinositol, phosphatidylserine and phosphatidylglycerol by housefly larvae. Lipids, 1971, 6, (7), 508-516
    • (1971) Lipids , vol.6 , Issue.7 , pp. 508-516
    • Hildenbrandt, G.R.1    Abraham, T.2    Bieber, L.L.3
  • 22
  • 23
    • 33646227441 scopus 로고    scopus 로고
    • Discovery of the molecular machinery CERT for endoplasmic reticulum-to-Golgi trafficking of ceramide
    • Hanada, K., Discovery of the molecular machinery CERT for endoplasmic reticulum-to-Golgi trafficking of ceramide. Mol Cell Biochem, 2006, 286, (1-2), 23-31
    • (2006) Mol Cell Biochem , vol.286 , Issue.1-2 , pp. 23-31
    • Hanada, K.1
  • 24
    • 0025323167 scopus 로고
    • Sphingomyelin synthesis in rat liver occurs predominantly at the cis and medial cisternae of the Golgi apparatus
    • Futerman, A.H.; Stieger, B.; Hubbard, A.L.; Pagano, R.E., Sphingomyelin synthesis in rat liver occurs predominantly at the cis and medial cisternae of the Golgi apparatus. J Biol Chem, 1990, 265, (15), 8650-8657
    • (1990) J Biol Chem , vol.265 , Issue.15 , pp. 8650-8657
    • Futerman, A.H.1    Stieger, B.2    Hubbard, A.L.3    Pagano, R.E.4
  • 25
    • 0025993036 scopus 로고
    • Determination of the intracellular sites and topology of glucosylceramide synthesis in rat liver
    • Futerman, A.H.; Pagano, R.E., Determination of the intracellular sites and topology of glucosylceramide synthesis in rat liver. Biochem J, 1991, 280 (Pt 2), 295-302
    • (1991) Biochem J , vol.280 , Issue.Pt 2 , pp. 295-302
    • Futerman, A.H.1    Pagano, R.E.2
  • 26
    • 0026552908 scopus 로고
    • Glucosylceramide is synthesized at the cytosolic surface of various Golgi subfractions
    • Jeckel, D.; Karrenbauer, A.; Burger, K.N.; van Meer, G.; Wieland, F., Glucosylceramide is synthesized at the cytosolic surface of various Golgi subfractions. J Cell Biol, 1992, 117, (2), 259-267
    • (1992) J Cell Biol , vol.117 , Issue.2 , pp. 259-267
    • Jeckel, D.1    Karrenbauer, A.2    Burger, K.N.3    van Meer, G.4    Wieland, F.5
  • 27
    • 0038050291 scopus 로고    scopus 로고
    • Lipid microdomains, lipid translocation and the organization of intracellular membrane transport (Review)
    • Holthuis, J.C.; van Meer, G.; Huitema, K., Lipid microdomains, lipid translocation and the organization of intracellular membrane transport (Review). Mol Membr Biol, 2003, 20, (3), 231-241
    • (2003) Mol Membr Biol , vol.20 , Issue.3 , pp. 231-241
    • Holthuis, J.C.1    van Meer, G.2    Huitema, K.3
  • 28
    • 38049092598 scopus 로고    scopus 로고
    • Sphingolipids and membrane biology as determined from genetic models
    • Rao, R.P.; Acharya, J.K., Sphingolipids and membrane biology as determined from genetic models. Prostaglandins Other Lipid Mediat, 2008, 85, (1-2), 1-16
    • (2008) Prostaglandins Other Lipid Mediat , vol.85 , Issue.1-2 , pp. 1-16
    • Rao, R.P.1    Acharya, J.K.2
  • 30
    • 0037203319 scopus 로고    scopus 로고
    • Sphingolipids, apoptosis, cancer treatments and the ovary: Investigating a crime against female fertility
    • Tilly, J.L.; Kolesnick, R.N., Sphingolipids, apoptosis, cancer treatments and the ovary: investigating a crime against female fertility. Biochim Biophys Acta, 2002, 1585, (2-3), 135-138
    • (2002) Biochim Biophys Acta , vol.1585 , Issue.2-3 , pp. 135-138
    • Tilly, J.L.1    Kolesnick, R.N.2
  • 33
    • 3543114272 scopus 로고    scopus 로고
    • Biologically active sphingolipids in cancer pathogenesis and treatment
    • Ogretmen, B.; Hannun, Y.A., Biologically active sphingolipids in cancer pathogenesis and treatment. Nat Rev Cancer, 2004, 4, (8), 604-616
    • (2004) Nat Rev Cancer , vol.4 , Issue.8 , pp. 604-616
    • Ogretmen, B.1    Hannun, Y.A.2
  • 34
    • 33847793485 scopus 로고    scopus 로고
    • Sphingosine-1-phosphate protects proliferating endothelial cells from ceramide-induced apoptosis but not from DNA damage-induced mitotic death
    • Bonnaud, S.; Niaudet, C.; Pottier, G.; Gaugler, M.H.; Millour, J.; Barbet, J.; Sabatier, L.; Paris, F., Sphingosine-1-phosphate protects proliferating endothelial cells from ceramide-induced apoptosis but not from DNA damage-induced mitotic death. Cancer Res, 2007, 67, (4), 1803-1811
    • (2007) Cancer Res , vol.67 , Issue.4 , pp. 1803-1811
    • Bonnaud, S.1    Niaudet, C.2    Pottier, G.3    Gaugler, M.H.4    Millour, J.5    Barbet, J.6    Sabatier, L.7    Paris, F.8
  • 35
    • 0034033925 scopus 로고    scopus 로고
    • Down-regulation of ceramide production abrogates ionizing radiation-induced cytochrome c release and apoptosis
    • Chmura, S.J.; Nodzenski, E.; Kharbanda, S.; Pandey, P.; Quintans, J.; Kufe, D.W.; Weichselbaum, R.R., Down-regulation of ceramide production abrogates ionizing radiation-induced cytochrome c release and apoptosis. Mol Pharmacol, 2000, 57, (4), 792-796
    • (2000) Mol Pharmacol , vol.57 , Issue.4 , pp. 792-796
    • Chmura, S.J.1    Nodzenski, E.2    Kharbanda, S.3    Pandey, P.4    Quintans, J.5    Kufe, D.W.6    Weichselbaum, R.R.7
  • 36
    • 33847007670 scopus 로고    scopus 로고
    • Pharmacological inhibition or small interfering RNA targeting acid ceramidase sensitizes hepatoma cells to chemotherapy and reduces tumor growth in vivo
    • Morales, A.; Paris, R.; Villanueva, A.; Llacuna, L.; Garcia-Ruiz, C.; Fernandez-Checa, J.C., Pharmacological inhibition or small interfering RNA targeting acid ceramidase sensitizes hepatoma cells to chemotherapy and reduces tumor growth in vivo. Oncogene, 2007, 26, (6), 905-916
    • (2007) Oncogene , vol.26 , Issue.6 , pp. 905-916
    • Morales, A.1    Paris, R.2    Villanueva, A.3    Llacuna, L.4    Garcia-Ruiz, C.5    Fernandez-Checa, J.C.6
  • 37
    • 1642293929 scopus 로고    scopus 로고
    • Ceramide selectively displaces cholesterol from ordered lipid domains (rafts): Implications for lipid raft structure and function
    • Megha; London, E., Ceramide selectively displaces cholesterol from ordered lipid domains (rafts): implications for lipid raft structure and function. J Biol Chem, 2004, 279, (11), 9997-10004
    • (2004) J Biol Chem , vol.279 , Issue.11 , pp. 9997-10004
    • Megha1    London, E.2
  • 38
    • 58149188064 scopus 로고    scopus 로고
    • Effects of ceramide and other simple sphingolipids on membrane lateral structure
    • Goni, F.M.; Alonso, A., Effects of ceramide and other simple sphingolipids on membrane lateral structure. Biochimica Et Biophysica Acta-Biomembranes, 2009, 1788, (1), 169-177
    • (2009) Biochimica Et Biophysica Acta-Biomembranes , vol.1788 , Issue.1 , pp. 169-177
    • Goni, F.M.1    Alonso, A.2
  • 40
    • 0027965006 scopus 로고
    • Protein kinase C zeta isoform is critical for kappa B-dependent promoter activation by sphingomyelinase
    • Lozano, J.; Berra, E.; Municio, M.M.; Diaz-Meco, M.T.; Dominguez, I.; Sanz, L.; Moscat, J., Protein kinase C zeta isoform is critical for kappa B-dependent promoter activation by sphingomyelinase. J Biol Chem, 1994, 269, (30), 19200-19202
    • (1994) J Biol Chem , vol.269 , Issue.30 , pp. 19200-19202
    • Lozano, J.1    Berra, E.2    Municio, M.M.3    Diaz-Meco, M.T.4    Dominguez, I.5    Sanz, L.6    Moscat, J.7
  • 42
    • 0032514918 scopus 로고    scopus 로고
    • BAD enables ceramide to signal apoptosis via Ras and Raf-1
    • Basu, S.; Bayoumy, S.; Zhang, Y.; Lozano, J.; Kolesnick, R., BAD enables ceramide to signal apoptosis via Ras and Raf-1. J Biol Chem, 1998, 273, (46), 30419-30426
    • (1998) J Biol Chem , vol.273 , Issue.46 , pp. 30419-30426
    • Basu, S.1    Bayoumy, S.2    Zhang, Y.3    Lozano, J.4    Kolesnick, R.5
  • 45
    • 0034634596 scopus 로고    scopus 로고
    • Ceramide directly activates protein kinase C zeta to regulate a stress-activated protein kinase signaling complex
    • Bourbon, N.A.; Yun, J.; Kester, M., Ceramide directly activates protein kinase C zeta to regulate a stress-activated protein kinase signaling complex. J Biol Chem, 2000, 275, (45), 35617-35623
    • (2000) J Biol Chem , vol.275 , Issue.45 , pp. 35617-35623
    • Bourbon, N.A.1    Yun, J.2    Kester, M.3
  • 47
    • 0037203316 scopus 로고    scopus 로고
    • Sphingosine in apoptosis signaling
    • Cuvillier, O., Sphingosine in apoptosis signaling. Biochim Biophys Acta, 2002, 1585, (2-3), 153-162
    • (2002) Biochim Biophys Acta , vol.1585 , Issue.2-3 , pp. 153-162
    • Cuvillier, O.1
  • 48
    • 0038218405 scopus 로고    scopus 로고
    • Sphingosine-1-phosphate: An enigmatic signalling lipid
    • Spiegel, S.; Milstien, S., Sphingosine-1-phosphate: an enigmatic signalling lipid. Nat Rev Mol Cell Biol, 2003, 4, (5), 397-407
    • (2003) Nat Rev Mol Cell Biol , vol.4 , Issue.5 , pp. 397-407
    • Spiegel, S.1    Milstien, S.2
  • 49
    • 33845294390 scopus 로고    scopus 로고
    • A house divided: Ceramide, sphingosine, and sphingosine-1-phosphate in programmed cell death
    • Taha, T.A.; Mullen, T.D.; Obeid, L.M., A house divided: ceramide, sphingosine, and sphingosine-1-phosphate in programmed cell death. Biochim Biophys Acta, 2006, 1758, (12), 2027-2036
    • (2006) Biochim Biophys Acta , vol.1758 , Issue.12 , pp. 2027-2036
    • Taha, T.A.1    Mullen, T.D.2    Obeid, L.M.3
  • 50
    • 77951889353 scopus 로고    scopus 로고
    • Sphingomyelin metabolism at the plasma membrane: Implications for bioactive sphingolipids
    • Milhas, D.; Clarke, C.J.; Hannun, Y.A., Sphingomyelin metabolism at the plasma membrane: implications for bioactive sphingolipids. FEBS Lett, 2009, 584, (9), 1887-1894
    • (2009) FEBS Lett , vol.584 , Issue.9 , pp. 1887-1894
    • Milhas, D.1    Clarke, C.J.2    Hannun, Y.A.3
  • 51
    • 0026540624 scopus 로고
    • Hypoxic injury to oligodendrocytes: Reversible inhibition of ATP-dependent transport of ceramide from the endoplasmic reticulum to the Golgi
    • Kendler, A.; Dawson, G., Hypoxic injury to oligodendrocytes: reversible inhibition of ATP-dependent transport of ceramide from the endoplasmic reticulum to the Golgi. J Neurosci Res, 1992, 31, (2), 205-211
    • (1992) J Neurosci Res , vol.31 , Issue.2 , pp. 205-211
    • Kendler, A.1    Dawson, G.2
  • 52
    • 0032509553 scopus 로고    scopus 로고
    • Mammalian cell mutants resistant to a sphingomyelindirected cytolysin. Genetic and biochemical evidence for complex formation of the LCB1 protein with the LCB2 protein for serine palmitoyltransferase
    • Hanada, K.; Hara, T.; Fukasawa, M.; Yamaji, A.; Umeda, M.; Nishijima, M., Mammalian cell mutants resistant to a sphingomyelindirected cytolysin. Genetic and biochemical evidence for complex formation of the LCB1 protein with the LCB2 protein for serine palmitoyltransferase. J Biol Chem, 1998, 273, (50), 33787-33794
    • (1998) J Biol Chem , vol.273 , Issue.50 , pp. 33787-33794
    • Hanada, K.1    Hara, T.2    Fukasawa, M.3    Yamaji, A.4    Umeda, M.5    Nishijima, M.6
  • 53
    • 0033593788 scopus 로고    scopus 로고
    • Genetic evidence for ATP-dependent endoplasmic reticulum-to-Golgi apparatus trafficking of ceramide for sphingomyelin synthesis in Chinese hamster ovary cells
    • Fukasawa, M.; Nishijima, M.; Hanada, K., Genetic evidence for ATP-dependent endoplasmic reticulum-to-Golgi apparatus trafficking of ceramide for sphingomyelin synthesis in Chinese hamster ovary cells. J Cell Biol, 1999, 144, (4), 673-685
    • (1999) J Cell Biol , vol.144 , Issue.4 , pp. 673-685
    • Fukasawa, M.1    Nishijima, M.2    Hanada, K.3
  • 54
    • 0034602382 scopus 로고    scopus 로고
    • Reduction of sphingomyelin level without accumulation of ceramide in Chinese hamster ovary cells affects detergent-resistant membrane domains and enhances cellular cholesterol efflux to methyl-beta -cyclodextrin
    • Fukasawa, M.; Nishijima, M.; Itabe, H.; Takano, T.; Hanada, K., Reduction of sphingomyelin level without accumulation of ceramide in Chinese hamster ovary cells affects detergent-resistant membrane domains and enhances cellular cholesterol efflux to methyl-beta -cyclodextrin. J Biol Chem, 2000, 275, (44), 34028-34034
    • (2000) J Biol Chem , vol.275 , Issue.44 , pp. 34028-34034
    • Fukasawa, M.1    Nishijima, M.2    Itabe, H.3    Takano, T.4    Hanada, K.5
  • 55
    • 0034730746 scopus 로고    scopus 로고
    • Reconstitution of ATP- and cytosol-dependent transport of de novo synthesized ceramide to the site of sphingomyelin synthesis in semi-intact cells
    • Funakoshi, T.; Yasuda, S.; Fukasawa, M.; Nishijima, M.; Hanada, K., Reconstitution of ATP- and cytosol-dependent transport of de novo synthesized ceramide to the site of sphingomyelin synthesis in semi-intact cells. J Biol Chem, 2000, 275, (39), 29938-29945
    • (2000) J Biol Chem , vol.275 , Issue.39 , pp. 29938-29945
    • Funakoshi, T.1    Yasuda, S.2    Fukasawa, M.3    Nishijima, M.4    Hanada, K.5
  • 56
    • 33749555280 scopus 로고    scopus 로고
    • Efficient trafficking of ceramide from the endoplasmic reticulum to the Golgi apparatus requires a VAMP-associated protein-interacting FFAT motif of CERT
    • Kawano, M.; Kumagai, K.; Nishijima, M.; Hanada, K., Efficient trafficking of ceramide from the endoplasmic reticulum to the Golgi apparatus requires a VAMP-associated protein-interacting FFAT motif of CERT. J Biol Chem, 2006, 281, (40), 30279-30288
    • (2006) J Biol Chem , vol.281 , Issue.40 , pp. 30279-30288
    • Kawano, M.1    Kumagai, K.2    Nishijima, M.3    Hanada, K.4
  • 57
    • 44449129087 scopus 로고    scopus 로고
    • Protein phosphatase 2Cepsilon is an endoplasmic reticulum integral membrane protein that dephosphorylates the ceramide transport protein CERT to enhance its association with organelle membranes
    • Saito, S.; Matsui, H.; Kawano, M.; Kumagai, K.; Tomishige, N.; Hanada, K.; Echigo, S.; Tamura, S.; Kobayashi, T., Protein phosphatase 2Cepsilon is an endoplasmic reticulum integral membrane protein that dephosphorylates the ceramide transport protein CERT to enhance its association with organelle membranes. J Biol Chem, 2008, 283, (10), 6584-6593
    • (2008) J Biol Chem , vol.283 , Issue.10 , pp. 6584-6593
    • Saito, S.1    Matsui, H.2    Kawano, M.3    Kumagai, K.4    Tomishige, N.5    Hanada, K.6    Echigo, S.7    Tamura, S.8    Kobayashi, T.9
  • 58
    • 63049110165 scopus 로고    scopus 로고
    • Casein kinase I{gamma}2 down-regulates trafficking of ceramide in the synthesis of sphingomyelin
    • Tomishige, N.; Kumagai, K.; Kusuda, J.; Nishijima, M.; Hanada, K., Casein kinase I{gamma}2 down-regulates trafficking of ceramide in the synthesis of sphingomyelin. Mol Biol Cell, 2009, 20, (1), 348-357
    • (2009) Mol Biol Cell , vol.20 , Issue.1 , pp. 348-357
    • Tomishige, N.1    Kumagai, K.2    Kusuda, J.3    Nishijima, M.4    Hanada, K.5
  • 59
    • 50649122795 scopus 로고    scopus 로고
    • Goodpasture antigen-binding protein and its spliced variant, ceramide transfer protein, have different functions in the modulation of apoptosis during zebrafish development
    • Granero-Molto, F.; Sarmah, S.; O'Rear, L.; Spagnoli, A.; Abrahamson, D.; Saus, J.; Hudson, B.G.; Knapik, E.W., Goodpasture antigen-binding protein and its spliced variant, ceramide transfer protein, have different functions in the modulation of apoptosis during zebrafish development. J Biol Chem, 2008, 283, (29), 20495-20504
    • (2008) J Biol Chem , vol.283 , Issue.29 , pp. 20495-20504
    • Granero-Molto, F.1    Sarmah, S.2    O'Rear, L.3    Spagnoli, A.4    Abrahamson, D.5    Saus, J.6    Hudson, B.G.7    Knapik, E.W.8
  • 63
    • 0035079539 scopus 로고    scopus 로고
    • Ceramide glycosylation potentiates cellular multidrug resistance
    • Liu, Y.Y.; Han, T.Y.; Giuliano, A.E.; Cabot, M.C., Ceramide glycosylation potentiates cellular multidrug resistance. FASEB J, 2001, 15, (3), 719-730
    • (2001) FASEB J , vol.15 , Issue.3 , pp. 719-730
    • Liu, Y.Y.1    Han, T.Y.2    Giuliano, A.E.3    Cabot, M.C.4
  • 64
    • 18144371163 scopus 로고    scopus 로고
    • Glucosylceramide synthase blockade down-regulates P-glycoprotein and resensitizes multidrug-resistant breast cancer cells to anticancer drugs
    • Gouaze, V.; Liu, Y.Y.; Prickett, C.S.; Yu, J.Y.; Giuliano, A.E.; Cabot, M.C., Glucosylceramide synthase blockade down-regulates P-glycoprotein and resensitizes multidrug-resistant breast cancer cells to anticancer drugs. Cancer Res, 2005, 65, (9), 3861-3867
    • (2005) Cancer Res , vol.65 , Issue.9 , pp. 3861-3867
    • Gouaze, V.1    Liu, Y.Y.2    Prickett, C.S.3    Yu, J.Y.4    Giuliano, A.E.5    Cabot, M.C.6
  • 65
    • 77950341123 scopus 로고    scopus 로고
    • Assessment of an RNA interference screen-derived mitotic and ceramide pathway metagene as a predictor of response to neoadjuvant paclitaxel for primary triplenegative breast cancer: A retrospective analysis of five clinical trials
    • Juul, N.; Szallasi, Z.; Eklund, A.C.; Li, Q.; Burrell, R.A.; Gerlinger, M.; Valero, V.; Andreopoulou, E.; Esteva, F.J.; Symmans, W.F.; Desmedt, C.; Haibe-Kains, B.; Sotiriou, C.; Pusztai, L.; Swanton, C., Assessment of an RNA interference screen-derived mitotic and ceramide pathway metagene as a predictor of response to neoadjuvant paclitaxel for primary triplenegative breast cancer: a retrospective analysis of five clinical trials. Lancet Oncol, 2010, 11, (4), 358-365
    • (2010) Lancet Oncol , vol.11 , Issue.4 , pp. 358-365
    • Juul, N.1    Szallasi, Z.2    Eklund, A.C.3    Li, Q.4    Burrell, R.A.5    Gerlinger, M.6    Valero, V.7    Andreopoulou, E.8    Esteva, F.J.9    Symmans, W.F.10    Desmedt, C.11    Haibe-Kains, B.12    Sotiriou, C.13    Pusztai, L.14    Swanton, C.15
  • 68
    • 14944349359 scopus 로고    scopus 로고
    • Apoptosis of non-smallcell lung cancer cell lines after paclitaxel treatment involves the BH3-only proapoptotic protein Bim
    • Li, R.; Moudgil, T.; Ross, H.J.; Hu, H.M., Apoptosis of non-smallcell lung cancer cell lines after paclitaxel treatment involves the BH3-only proapoptotic protein Bim. Cell Death Differ, 2005, 12, (3), 292-303.
    • (2005) Cell Death Differ , vol.12 , Issue.3 , pp. 292-303
    • Li, R.1    Moudgil, T.2    Ross, H.J.3    Hu, H.M.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.