-
1
-
-
13244255551
-
Enzymes of sphingolipid metabolism in Drosophila melanogaster
-
Acharya, U.; Acharya, J.K., Enzymes of sphingolipid metabolism in Drosophila melanogaster. Cell Mol Life Sci, 2005, 62, (2), 128-142
-
(2005)
Cell Mol Life Sci
, vol.62
, Issue.2
, pp. 128-142
-
-
Acharya, U.1
Acharya, J.K.2
-
2
-
-
38549152194
-
Principles of bioactive lipid signalling: Lessons from sphingolipids
-
Hannun, Y.A.; Obeid, L.M., Principles of bioactive lipid signalling: lessons from sphingolipids. Nat Rev Mol Cell Biol, 2008, 9, (2), 139-150
-
(2008)
Nat Rev Mol Cell Biol
, vol.9
, Issue.2
, pp. 139-150
-
-
Hannun, Y.A.1
Obeid, L.M.2
-
3
-
-
78049507803
-
Gangliosides as regulators of cell membrane organization and functions
-
Sonnino, S.; Prinetti, A., Gangliosides as regulators of cell membrane organization and functions. Adv Exp Med Biol, 2010, 688, 165-184
-
(2010)
Adv Exp Med Biol
, vol.688
, pp. 165-184
-
-
Sonnino, S.1
Prinetti, A.2
-
4
-
-
27844517355
-
Sphingosine 1-phosphate and ceramide 1-phosphate: Expanding roles in cell signaling
-
Chalfant, C.E.; Spiegel, S., Sphingosine 1-phosphate and ceramide 1-phosphate: expanding roles in cell signaling. J Cell Sci, 2005, 118, (Pt 20), 4605-4612
-
(2005)
J Cell Sci
, vol.118
, Issue.Pt 20
, pp. 4605-4612
-
-
Chalfant, C.E.1
Spiegel, S.2
-
5
-
-
77956394811
-
A lipid matrix model of membrane raft structure
-
Quinn, P.J., A lipid matrix model of membrane raft structure. Progress in lipid research, 2010, 49, (4), 390-406
-
(2010)
Progress In Lipid Research
, vol.49
, Issue.4
, pp. 390-406
-
-
Quinn, P.J.1
-
6
-
-
59849097154
-
Mitochondrial degeneration and not apoptosis is the primary cause of embryonic lethality in ceramide transfer protein mutant mice
-
Wang, X.; Rao, R.P.; Kosakowska-Cholody, T.; Masood, M.A.; Southon, E.; Zhang, H.; Berthet, C.; Nagashim, K.; Veenstra, T.K.; Tessarollo, L.; Acharya, U.; Acharya, J.K., Mitochondrial degeneration and not apoptosis is the primary cause of embryonic lethality in ceramide transfer protein mutant mice. J Cell Biol, 2009, 184, (1), 143-158
-
(2009)
J Cell Biol
, vol.184
, Issue.1
, pp. 143-158
-
-
Wang, X.1
Rao, R.P.2
Kosakowska-Cholody, T.3
Masood, M.A.4
Southon, E.5
Zhang, H.6
Berthet, C.7
Nagashim, K.8
Veenstra, T.K.9
Tessarollo, L.10
Acharya, U.11
Acharya, J.K.12
-
7
-
-
34547453153
-
Ceramide transfer protein function is essential for normal oxidative stress response and lifespan
-
Rao, R.P.; Yuan, C.; Allegood, J.C.; Rawat, S.S.; Edwards, M.B.; Wang, X.; Merrill, A.H., Jr.; Acharya, U.; Acharya, J.K., Ceramide transfer protein function is essential for normal oxidative stress response and lifespan. Proc Natl Acad Sci U S A, 2007, 104, (27), 11364-11369
-
(2007)
Proc Natl Acad Sci U S A
, vol.104
, Issue.27
, pp. 11364-11369
-
-
Rao, R.P.1
Yuan, C.2
Allegood, J.C.3
Rawat, S.S.4
Edwards, M.B.5
Wang, X.6
Merrill Jr., A.H.7
Acharya, U.8
Acharya, J.K.9
-
8
-
-
27644537134
-
Serine palmitoyl-CoA transferase (SPT) deficiency and sphingolipid levels in mice
-
Hojjati, M.R.; Li, Z.; Jiang, X.-C., Serine palmitoyl-CoA transferase (SPT) deficiency and sphingolipid levels in mice. Biochimica et biophysica acta, 2005, 1737, (1), 44-51
-
(2005)
Biochimica Et Biophysica Acta
, vol.1737
, Issue.1
, pp. 44-51
-
-
Hojjati, M.R.1
Li, Z.2
Jiang, X.-C.3
-
9
-
-
78049498377
-
Sphingolipid transport
-
Riboni, L.; Giussani, P.; Viani, P., Sphingolipid transport. Advances in experimental medicine and biology, 2010, 688, 24-45
-
(2010)
Advances In Experimental Medicine and Biology
, vol.688
, pp. 24-45
-
-
Riboni, L.1
Giussani, P.2
Viani, P.3
-
10
-
-
78649373124
-
Membranes in balance: Mechanisms of sphingolipid homeostasis
-
Breslow, D.K.; Weissman, J.S., Membranes in balance: mechanisms of sphingolipid homeostasis. Molecular cell, 2010, 40, (2), 267-279
-
(2010)
Molecular Cell
, vol.40
, Issue.2
, pp. 267-279
-
-
Breslow, D.K.1
Weissman, J.S.2
-
11
-
-
0035842889
-
Vesicular and nonvesicular transport of ceramide from ER to the Golgi apparatus in yeast
-
Funato, K.; Riezman, H., Vesicular and nonvesicular transport of ceramide from ER to the Golgi apparatus in yeast. J Cell Biol, 2001, 155, (6), 949-959
-
(2001)
J Cell Biol
, vol.155
, Issue.6
, pp. 949-959
-
-
Funato, K.1
Riezman, H.2
-
12
-
-
0026465549
-
Sphingolipid transport in mitotic HeLa cells
-
Collins, R.N.; Warren, G., Sphingolipid transport in mitotic HeLa cells. J Biol Chem, 1992, 267, (34), 24906-24911
-
(1992)
J Biol Chem
, vol.267
, Issue.34
, pp. 24906-24911
-
-
Collins, R.N.1
Warren, G.2
-
13
-
-
0032143958
-
Ceramide transport from endoplasmic reticulum to Golgi apparatus is not vesicle-mediated
-
Kok, J.W.; Babia, T.; Klappe, K.; Egea, G.; Hoekstra, D., Ceramide transport from endoplasmic reticulum to Golgi apparatus is not vesicle-mediated. Biochem J, 1998, 333 (Pt 3), 779-786
-
(1998)
Biochem J
, vol.333
, Issue.Pt 3
, pp. 779-786
-
-
Kok, J.W.1
Babia, T.2
Klappe, K.3
Egea, G.4
Hoekstra, D.5
-
14
-
-
0027447066
-
Ceramide excluded from cell-free vesicular lipid transfer from endoplasmic reticulum to Golgi apparatus. Evidence for lipid sorting
-
Moreau, P.; Cassagne, C.; Keenan, T.W.; Morre, D.J., Ceramide excluded from cell-free vesicular lipid transfer from endoplasmic reticulum to Golgi apparatus. Evidence for lipid sorting. Biochim Biophys Acta, 1993, 1146, (1), 9-16
-
(1993)
Biochim Biophys Acta
, vol.1146
, Issue.1
, pp. 9-16
-
-
Moreau, P.1
Cassagne, C.2
Keenan, T.W.3
Morre, D.J.4
-
15
-
-
0347611095
-
Molecular machinery for non-vesicular trafficking of ceramide
-
Hanada, K.; Kumagai, K.; Yasuda, S.; Miura, Y.; Kawano, M.; Fukasawa, M.; Nishijima, M., Molecular machinery for non-vesicular trafficking of ceramide. Nature, 2003, 426, (6968), 803-809
-
(2003)
Nature
, vol.426
, Issue.6968
, pp. 803-809
-
-
Hanada, K.1
Kumagai, K.2
Yasuda, S.3
Miura, Y.4
Kawano, M.5
Fukasawa, M.6
Nishijima, M.7
-
16
-
-
78049510823
-
Cancer treatment strategies targeting sphingolipid metabolism
-
Oskouian, B.; Saba, J.D., Cancer treatment strategies targeting sphingolipid metabolism. Advances in experimental medicine and biology, 2010, 688, 185-205
-
(2010)
Advances In Experimental Medicine and Biology
, vol.688
, pp. 185-205
-
-
Oskouian, B.1
Saba, J.D.2
-
17
-
-
0036517315
-
Teaching students to care for and about people with disabilities
-
Wilson, J.S.; Merrill, A.S., Teaching students to care for and about people with disabilities. Nurse Educ, 2002, 27, (2), 89-93
-
(2002)
Nurse Educ
, vol.27
, Issue.2
, pp. 89-93
-
-
Wilson, J.S.1
Merrill, A.S.2
-
18
-
-
0033947176
-
Sphingolipids
-
Shayman, J.A., Sphingolipids. Kidney Int, 2000, 58, (1), 11-26
-
(2000)
Kidney Int
, vol.58
, Issue.1
, pp. 11-26
-
-
Shayman, J.A.1
-
19
-
-
0037071871
-
Sphingolipid functions in Saccharomyces cerevisiae
-
Dickson, R.C.; Lester, R.L., Sphingolipid functions in Saccharomyces cerevisiae. Biochim Biophys Acta, 2002, 1583, (1), 13-25
-
(2002)
Biochim Biophys Acta
, vol.1583
, Issue.1
, pp. 13-25
-
-
Dickson, R.C.1
Lester, R.L.2
-
20
-
-
0014694821
-
The occurrence of tetradecasphing-4-enine and hexadecasphing-4-enine as the principal sphingosines of Musca domestica larvae and adults
-
Bieber, L.L.; O'Connor, J.D.; Sweeley, C.C., The occurrence of tetradecasphing-4-enine and hexadecasphing-4-enine as the principal sphingosines of Musca domestica larvae and adults. Biochim Biophys Acta, 1969, 187, (1), 157-159
-
(1969)
Biochim Biophys Acta
, vol.187
, Issue.1
, pp. 157-159
-
-
Bieber, L.L.1
O'Connor, J.D.2
Sweeley, C.C.3
-
21
-
-
0015087107
-
Metabolism of ceramide phosphorylethanolamine, phosphatidylinositol, phosphatidylserine and phosphatidylglycerol by housefly larvae
-
Hildenbrandt, G.R.; Abraham, T.; Bieber, L.L., Metabolism of ceramide phosphorylethanolamine, phosphatidylinositol, phosphatidylserine and phosphatidylglycerol by housefly larvae. Lipids, 1971, 6, (7), 508-516
-
(1971)
Lipids
, vol.6
, Issue.7
, pp. 508-516
-
-
Hildenbrandt, G.R.1
Abraham, T.2
Bieber, L.L.3
-
22
-
-
2342510923
-
Yeast sphingolipid metabolism: Clues and connections
-
Sims, K.J.; Spassieva, S.D.; Voit, E.O.; Obeid, L.M., Yeast sphingolipid metabolism: clues and connections. Biochem Cell Biol, 2004, 82, (1), 45-61
-
(2004)
Biochem Cell Biol
, vol.82
, Issue.1
, pp. 45-61
-
-
Sims, K.J.1
Spassieva, S.D.2
Voit, E.O.3
Obeid, L.M.4
-
23
-
-
33646227441
-
Discovery of the molecular machinery CERT for endoplasmic reticulum-to-Golgi trafficking of ceramide
-
Hanada, K., Discovery of the molecular machinery CERT for endoplasmic reticulum-to-Golgi trafficking of ceramide. Mol Cell Biochem, 2006, 286, (1-2), 23-31
-
(2006)
Mol Cell Biochem
, vol.286
, Issue.1-2
, pp. 23-31
-
-
Hanada, K.1
-
24
-
-
0025323167
-
Sphingomyelin synthesis in rat liver occurs predominantly at the cis and medial cisternae of the Golgi apparatus
-
Futerman, A.H.; Stieger, B.; Hubbard, A.L.; Pagano, R.E., Sphingomyelin synthesis in rat liver occurs predominantly at the cis and medial cisternae of the Golgi apparatus. J Biol Chem, 1990, 265, (15), 8650-8657
-
(1990)
J Biol Chem
, vol.265
, Issue.15
, pp. 8650-8657
-
-
Futerman, A.H.1
Stieger, B.2
Hubbard, A.L.3
Pagano, R.E.4
-
25
-
-
0025993036
-
Determination of the intracellular sites and topology of glucosylceramide synthesis in rat liver
-
Futerman, A.H.; Pagano, R.E., Determination of the intracellular sites and topology of glucosylceramide synthesis in rat liver. Biochem J, 1991, 280 (Pt 2), 295-302
-
(1991)
Biochem J
, vol.280
, Issue.Pt 2
, pp. 295-302
-
-
Futerman, A.H.1
Pagano, R.E.2
-
26
-
-
0026552908
-
Glucosylceramide is synthesized at the cytosolic surface of various Golgi subfractions
-
Jeckel, D.; Karrenbauer, A.; Burger, K.N.; van Meer, G.; Wieland, F., Glucosylceramide is synthesized at the cytosolic surface of various Golgi subfractions. J Cell Biol, 1992, 117, (2), 259-267
-
(1992)
J Cell Biol
, vol.117
, Issue.2
, pp. 259-267
-
-
Jeckel, D.1
Karrenbauer, A.2
Burger, K.N.3
van Meer, G.4
Wieland, F.5
-
27
-
-
0038050291
-
Lipid microdomains, lipid translocation and the organization of intracellular membrane transport (Review)
-
Holthuis, J.C.; van Meer, G.; Huitema, K., Lipid microdomains, lipid translocation and the organization of intracellular membrane transport (Review). Mol Membr Biol, 2003, 20, (3), 231-241
-
(2003)
Mol Membr Biol
, vol.20
, Issue.3
, pp. 231-241
-
-
Holthuis, J.C.1
van Meer, G.2
Huitema, K.3
-
28
-
-
38049092598
-
Sphingolipids and membrane biology as determined from genetic models
-
Rao, R.P.; Acharya, J.K., Sphingolipids and membrane biology as determined from genetic models. Prostaglandins Other Lipid Mediat, 2008, 85, (1-2), 1-16
-
(2008)
Prostaglandins Other Lipid Mediat
, vol.85
, Issue.1-2
, pp. 1-16
-
-
Rao, R.P.1
Acharya, J.K.2
-
29
-
-
33751064261
-
Combined therapeutic use of AdGFPFasL and small molecule inhibitors of ceramide metabolism in prostate and head and neck cancers: A status report
-
Norris, J.S.; Bielawska, A.; Day, T.; El-Zawahri, A.; ElOjeimy, S.; Hannun, Y.; Holman, D.; Hyer, M.; Landon, C.; Lowe, S.; Dong, J.Y.; McKillop, J.; Norris, K.; Obeid, L.; Rubinchik, S.; Tavassoli, M.; Tomlinson, S.; Voelkel-Johnson, C.; Liu, X., Combined therapeutic use of AdGFPFasL and small molecule inhibitors of ceramide metabolism in prostate and head and neck cancers: a status report. Cancer Gene Ther, 2006, 13, (12), 1045-1051
-
(2006)
Cancer Gene Ther
, vol.13
, Issue.12
, pp. 1045-1051
-
-
Norris, J.S.1
Bielawska, A.2
Day, T.3
El-Zawahri, A.4
Elojeimy, S.5
Hannun, Y.6
Holman, D.7
Hyer, M.8
Landon, C.9
Lowe, S.10
Dong, J.Y.11
McKillop, J.12
Norris, K.13
Obeid, L.14
Rubinchik, S.15
Tavassoli, M.16
Tomlinson, S.17
Voelkel-Johnson, C.18
Liu, X.19
-
30
-
-
0037203319
-
Sphingolipids, apoptosis, cancer treatments and the ovary: Investigating a crime against female fertility
-
Tilly, J.L.; Kolesnick, R.N., Sphingolipids, apoptosis, cancer treatments and the ovary: investigating a crime against female fertility. Biochim Biophys Acta, 2002, 1585, (2-3), 135-138
-
(2002)
Biochim Biophys Acta
, vol.1585
, Issue.2-3
, pp. 135-138
-
-
Tilly, J.L.1
Kolesnick, R.N.2
-
31
-
-
47149105082
-
Mutations in the neutral sphingomyelinase gene SMPD3 implicate the ceramide pathway in human leukemias
-
Kim, W.J.; Okimoto, R.A.; Purton, L.E.; Goodwin, M.; Haserlat, S.M.; Dayyani, F.; Sweetser, D.A.; McClatchey, A.I.; Bernard, O.A.; Look, A.T.; Bell, D.W.; Scadden, D.T.; Haber, D.A., Mutations in the neutral sphingomyelinase gene SMPD3 implicate the ceramide pathway in human leukemias. Blood, 2008, 111, (9), 4716-4722
-
(2008)
Blood
, vol.111
, Issue.9
, pp. 4716-4722
-
-
Kim, W.J.1
Okimoto, R.A.2
Purton, L.E.3
Goodwin, M.4
Haserlat, S.M.5
Dayyani, F.6
Sweetser, D.A.7
McClatchey, A.I.8
Bernard, O.A.9
Look, A.T.10
Bell, D.W.11
Scadden, D.T.12
Haber, D.A.13
-
32
-
-
52949143502
-
Microarray analysis of altered sphingolipid metabolism reveals prognostic significance of sphingosine kinase 1 in breast cancer
-
Ruckhaberle, E.; Rody, A.; Engels, K.; Gaetje, R.; von Minckwitz, G.; Schiffmann, S.; Grosch, S.; Geisslinger, G.; Holtrich, U.; Karn, T.; Kaufmann, M., Microarray analysis of altered sphingolipid metabolism reveals prognostic significance of sphingosine kinase 1 in breast cancer. Breast Cancer Res Treat, 2008, 112, (1), 41-52
-
(2008)
Breast Cancer Res Treat
, vol.112
, Issue.1
, pp. 41-52
-
-
Ruckhaberle, E.1
Rody, A.2
Engels, K.3
Gaetje, R.4
von Minckwitz, G.5
Schiffmann, S.6
Grosch, S.7
Geisslinger, G.8
Holtrich, U.9
Karn, T.10
Kaufmann, M.11
-
33
-
-
3543114272
-
Biologically active sphingolipids in cancer pathogenesis and treatment
-
Ogretmen, B.; Hannun, Y.A., Biologically active sphingolipids in cancer pathogenesis and treatment. Nat Rev Cancer, 2004, 4, (8), 604-616
-
(2004)
Nat Rev Cancer
, vol.4
, Issue.8
, pp. 604-616
-
-
Ogretmen, B.1
Hannun, Y.A.2
-
34
-
-
33847793485
-
Sphingosine-1-phosphate protects proliferating endothelial cells from ceramide-induced apoptosis but not from DNA damage-induced mitotic death
-
Bonnaud, S.; Niaudet, C.; Pottier, G.; Gaugler, M.H.; Millour, J.; Barbet, J.; Sabatier, L.; Paris, F., Sphingosine-1-phosphate protects proliferating endothelial cells from ceramide-induced apoptosis but not from DNA damage-induced mitotic death. Cancer Res, 2007, 67, (4), 1803-1811
-
(2007)
Cancer Res
, vol.67
, Issue.4
, pp. 1803-1811
-
-
Bonnaud, S.1
Niaudet, C.2
Pottier, G.3
Gaugler, M.H.4
Millour, J.5
Barbet, J.6
Sabatier, L.7
Paris, F.8
-
35
-
-
0034033925
-
Down-regulation of ceramide production abrogates ionizing radiation-induced cytochrome c release and apoptosis
-
Chmura, S.J.; Nodzenski, E.; Kharbanda, S.; Pandey, P.; Quintans, J.; Kufe, D.W.; Weichselbaum, R.R., Down-regulation of ceramide production abrogates ionizing radiation-induced cytochrome c release and apoptosis. Mol Pharmacol, 2000, 57, (4), 792-796
-
(2000)
Mol Pharmacol
, vol.57
, Issue.4
, pp. 792-796
-
-
Chmura, S.J.1
Nodzenski, E.2
Kharbanda, S.3
Pandey, P.4
Quintans, J.5
Kufe, D.W.6
Weichselbaum, R.R.7
-
36
-
-
33847007670
-
Pharmacological inhibition or small interfering RNA targeting acid ceramidase sensitizes hepatoma cells to chemotherapy and reduces tumor growth in vivo
-
Morales, A.; Paris, R.; Villanueva, A.; Llacuna, L.; Garcia-Ruiz, C.; Fernandez-Checa, J.C., Pharmacological inhibition or small interfering RNA targeting acid ceramidase sensitizes hepatoma cells to chemotherapy and reduces tumor growth in vivo. Oncogene, 2007, 26, (6), 905-916
-
(2007)
Oncogene
, vol.26
, Issue.6
, pp. 905-916
-
-
Morales, A.1
Paris, R.2
Villanueva, A.3
Llacuna, L.4
Garcia-Ruiz, C.5
Fernandez-Checa, J.C.6
-
37
-
-
1642293929
-
Ceramide selectively displaces cholesterol from ordered lipid domains (rafts): Implications for lipid raft structure and function
-
Megha; London, E., Ceramide selectively displaces cholesterol from ordered lipid domains (rafts): implications for lipid raft structure and function. J Biol Chem, 2004, 279, (11), 9997-10004
-
(2004)
J Biol Chem
, vol.279
, Issue.11
, pp. 9997-10004
-
-
Megha1
London, E.2
-
38
-
-
58149188064
-
Effects of ceramide and other simple sphingolipids on membrane lateral structure
-
Goni, F.M.; Alonso, A., Effects of ceramide and other simple sphingolipids on membrane lateral structure. Biochimica Et Biophysica Acta-Biomembranes, 2009, 1788, (1), 169-177
-
(2009)
Biochimica Et Biophysica Acta-Biomembranes
, vol.1788
, Issue.1
, pp. 169-177
-
-
Goni, F.M.1
Alonso, A.2
-
39
-
-
73949113416
-
Ceramide kinase regulates phospholipase C and phosphatidylinositol 4, 5, bisphosphate in phototransduction
-
Dasgupta, U.; Bamba, T.; Chiantia, S.; Karim, P.; Tayoun, A.N.; Yonamine, I.; Rawat, S.S.; Rao, R.P.; Nagashima, K.; Fukusaki, E.; Puri, V.; Dolph, P.J.; Schwille, P.; Acharya, J.K.; Acharya, U., Ceramide kinase regulates phospholipase C and phosphatidylinositol 4, 5, bisphosphate in phototransduction. Proc Natl Acad Sci U S A, 2009, 106, (47), 20063-20068
-
(2009)
Proc Natl Acad Sci U S A
, vol.106
, Issue.47
, pp. 20063-20068
-
-
Dasgupta, U.1
Bamba, T.2
Chiantia, S.3
Karim, P.4
Tayoun, A.N.5
Yonamine, I.6
Rawat, S.S.7
Rao, R.P.8
Nagashima, K.9
Fukusaki, E.10
Puri, V.11
Dolph, P.J.12
Schwille, P.13
Acharya, J.K.14
Acharya, U.15
-
40
-
-
0027965006
-
Protein kinase C zeta isoform is critical for kappa B-dependent promoter activation by sphingomyelinase
-
Lozano, J.; Berra, E.; Municio, M.M.; Diaz-Meco, M.T.; Dominguez, I.; Sanz, L.; Moscat, J., Protein kinase C zeta isoform is critical for kappa B-dependent promoter activation by sphingomyelinase. J Biol Chem, 1994, 269, (30), 19200-19202
-
(1994)
J Biol Chem
, vol.269
, Issue.30
, pp. 19200-19202
-
-
Lozano, J.1
Berra, E.2
Municio, M.M.3
Diaz-Meco, M.T.4
Dominguez, I.5
Sanz, L.6
Moscat, J.7
-
41
-
-
0343742670
-
Kinase suppressor of Ras is ceramide-activated protein kinase
-
Zhang, Y.; Yao, B.; Delikat, S.; Bayoumy, S.; Lin, X.H.; Basu, S.; McGinley, M.; Chan-Hui, P.Y.; Lichenstein, H.; Kolesnick, R., Kinase suppressor of Ras is ceramide-activated protein kinase. Cell, 1997, 89, (1), 63-72
-
(1997)
Cell
, vol.89
, Issue.1
, pp. 63-72
-
-
Zhang, Y.1
Yao, B.2
Delikat, S.3
Bayoumy, S.4
Lin, X.H.5
Basu, S.6
McGinley, M.7
Chan-Hui, P.Y.8
Lichenstein, H.9
Kolesnick, R.10
-
42
-
-
0032514918
-
BAD enables ceramide to signal apoptosis via Ras and Raf-1
-
Basu, S.; Bayoumy, S.; Zhang, Y.; Lozano, J.; Kolesnick, R., BAD enables ceramide to signal apoptosis via Ras and Raf-1. J Biol Chem, 1998, 273, (46), 30419-30426
-
(1998)
J Biol Chem
, vol.273
, Issue.46
, pp. 30419-30426
-
-
Basu, S.1
Bayoumy, S.2
Zhang, Y.3
Lozano, J.4
Kolesnick, R.5
-
43
-
-
0033214095
-
Cathepsin D targeted by acid sphingomyelinase-derived ceramide
-
Heinrich, M.; Wickel, M.; Schneider-Brachert, W.; Sandberg, C.; Gahr, J.; Schwandner, R.; Weber, T.; Saftig, P.; Peters, C.; Brunner, J.; Kronke, M.; Schutze, S., Cathepsin D targeted by acid sphingomyelinase-derived ceramide. EMBO J, 1999, 18, (19), 5252-5263
-
(1999)
EMBO J
, vol.18
, Issue.19
, pp. 5252-5263
-
-
Heinrich, M.1
Wickel, M.2
Schneider-Brachert, W.3
Sandberg, C.4
Gahr, J.5
Schwandner, R.6
Weber, T.7
Saftig, P.8
Peters, C.9
Brunner, J.10
Kronke, M.11
Schutze, S.12
-
44
-
-
2442661614
-
Cathepsin D links TNFinduced acid sphingomyelinase to Bid-mediated caspase-9 and -3 activation
-
Heinrich, M.; Neumeyer, J.; Jakob, M.; Hallas, C.; Tchikov, V.; Winoto-Morbach, S.; Wickel, M.; Schneider-Brachert, W.; Trauzold, A.; Hethke, A.; Schutze, S., Cathepsin D links TNFinduced acid sphingomyelinase to Bid-mediated caspase-9 and -3 activation. Cell Death Differ, 2004, 11, (5), 550-563
-
(2004)
Cell Death Differ
, vol.11
, Issue.5
, pp. 550-563
-
-
Heinrich, M.1
Neumeyer, J.2
Jakob, M.3
Hallas, C.4
Tchikov, V.5
Winoto-Morbach, S.6
Wickel, M.7
Schneider-Brachert, W.8
Trauzold, A.9
Hethke, A.10
Schutze, S.11
-
45
-
-
0034634596
-
Ceramide directly activates protein kinase C zeta to regulate a stress-activated protein kinase signaling complex
-
Bourbon, N.A.; Yun, J.; Kester, M., Ceramide directly activates protein kinase C zeta to regulate a stress-activated protein kinase signaling complex. J Biol Chem, 2000, 275, (45), 35617-35623
-
(2000)
J Biol Chem
, vol.275
, Issue.45
, pp. 35617-35623
-
-
Bourbon, N.A.1
Yun, J.2
Kester, M.3
-
46
-
-
79955799347
-
A role of sphingosine kinase 1 in head and neck carcinogenesis
-
Shirai, K.; Kaneshiro, T.; Wada, M.; Furuya, H.; Bielawski, J.; Hannun, Y.A.; Obeid, L.M.; Ogretmen, B.; Kawamori, T., A role of sphingosine kinase 1 in head and neck carcinogenesis. Cancer Prev Res (Phila), 2011, 4, (3), 454-462
-
(2011)
Cancer Prev Res (Phila)
, vol.4
, Issue.3
, pp. 454-462
-
-
Shirai, K.1
Kaneshiro, T.2
Wada, M.3
Furuya, H.4
Bielawski, J.5
Hannun, Y.A.6
Obeid, L.M.7
Ogretmen, B.8
Kawamori, T.9
-
47
-
-
0037203316
-
Sphingosine in apoptosis signaling
-
Cuvillier, O., Sphingosine in apoptosis signaling. Biochim Biophys Acta, 2002, 1585, (2-3), 153-162
-
(2002)
Biochim Biophys Acta
, vol.1585
, Issue.2-3
, pp. 153-162
-
-
Cuvillier, O.1
-
48
-
-
0038218405
-
Sphingosine-1-phosphate: An enigmatic signalling lipid
-
Spiegel, S.; Milstien, S., Sphingosine-1-phosphate: an enigmatic signalling lipid. Nat Rev Mol Cell Biol, 2003, 4, (5), 397-407
-
(2003)
Nat Rev Mol Cell Biol
, vol.4
, Issue.5
, pp. 397-407
-
-
Spiegel, S.1
Milstien, S.2
-
49
-
-
33845294390
-
A house divided: Ceramide, sphingosine, and sphingosine-1-phosphate in programmed cell death
-
Taha, T.A.; Mullen, T.D.; Obeid, L.M., A house divided: ceramide, sphingosine, and sphingosine-1-phosphate in programmed cell death. Biochim Biophys Acta, 2006, 1758, (12), 2027-2036
-
(2006)
Biochim Biophys Acta
, vol.1758
, Issue.12
, pp. 2027-2036
-
-
Taha, T.A.1
Mullen, T.D.2
Obeid, L.M.3
-
50
-
-
77951889353
-
Sphingomyelin metabolism at the plasma membrane: Implications for bioactive sphingolipids
-
Milhas, D.; Clarke, C.J.; Hannun, Y.A., Sphingomyelin metabolism at the plasma membrane: implications for bioactive sphingolipids. FEBS Lett, 2009, 584, (9), 1887-1894
-
(2009)
FEBS Lett
, vol.584
, Issue.9
, pp. 1887-1894
-
-
Milhas, D.1
Clarke, C.J.2
Hannun, Y.A.3
-
51
-
-
0026540624
-
Hypoxic injury to oligodendrocytes: Reversible inhibition of ATP-dependent transport of ceramide from the endoplasmic reticulum to the Golgi
-
Kendler, A.; Dawson, G., Hypoxic injury to oligodendrocytes: reversible inhibition of ATP-dependent transport of ceramide from the endoplasmic reticulum to the Golgi. J Neurosci Res, 1992, 31, (2), 205-211
-
(1992)
J Neurosci Res
, vol.31
, Issue.2
, pp. 205-211
-
-
Kendler, A.1
Dawson, G.2
-
52
-
-
0032509553
-
Mammalian cell mutants resistant to a sphingomyelindirected cytolysin. Genetic and biochemical evidence for complex formation of the LCB1 protein with the LCB2 protein for serine palmitoyltransferase
-
Hanada, K.; Hara, T.; Fukasawa, M.; Yamaji, A.; Umeda, M.; Nishijima, M., Mammalian cell mutants resistant to a sphingomyelindirected cytolysin. Genetic and biochemical evidence for complex formation of the LCB1 protein with the LCB2 protein for serine palmitoyltransferase. J Biol Chem, 1998, 273, (50), 33787-33794
-
(1998)
J Biol Chem
, vol.273
, Issue.50
, pp. 33787-33794
-
-
Hanada, K.1
Hara, T.2
Fukasawa, M.3
Yamaji, A.4
Umeda, M.5
Nishijima, M.6
-
53
-
-
0033593788
-
Genetic evidence for ATP-dependent endoplasmic reticulum-to-Golgi apparatus trafficking of ceramide for sphingomyelin synthesis in Chinese hamster ovary cells
-
Fukasawa, M.; Nishijima, M.; Hanada, K., Genetic evidence for ATP-dependent endoplasmic reticulum-to-Golgi apparatus trafficking of ceramide for sphingomyelin synthesis in Chinese hamster ovary cells. J Cell Biol, 1999, 144, (4), 673-685
-
(1999)
J Cell Biol
, vol.144
, Issue.4
, pp. 673-685
-
-
Fukasawa, M.1
Nishijima, M.2
Hanada, K.3
-
54
-
-
0034602382
-
Reduction of sphingomyelin level without accumulation of ceramide in Chinese hamster ovary cells affects detergent-resistant membrane domains and enhances cellular cholesterol efflux to methyl-beta -cyclodextrin
-
Fukasawa, M.; Nishijima, M.; Itabe, H.; Takano, T.; Hanada, K., Reduction of sphingomyelin level without accumulation of ceramide in Chinese hamster ovary cells affects detergent-resistant membrane domains and enhances cellular cholesterol efflux to methyl-beta -cyclodextrin. J Biol Chem, 2000, 275, (44), 34028-34034
-
(2000)
J Biol Chem
, vol.275
, Issue.44
, pp. 34028-34034
-
-
Fukasawa, M.1
Nishijima, M.2
Itabe, H.3
Takano, T.4
Hanada, K.5
-
55
-
-
0034730746
-
Reconstitution of ATP- and cytosol-dependent transport of de novo synthesized ceramide to the site of sphingomyelin synthesis in semi-intact cells
-
Funakoshi, T.; Yasuda, S.; Fukasawa, M.; Nishijima, M.; Hanada, K., Reconstitution of ATP- and cytosol-dependent transport of de novo synthesized ceramide to the site of sphingomyelin synthesis in semi-intact cells. J Biol Chem, 2000, 275, (39), 29938-29945
-
(2000)
J Biol Chem
, vol.275
, Issue.39
, pp. 29938-29945
-
-
Funakoshi, T.1
Yasuda, S.2
Fukasawa, M.3
Nishijima, M.4
Hanada, K.5
-
56
-
-
33749555280
-
Efficient trafficking of ceramide from the endoplasmic reticulum to the Golgi apparatus requires a VAMP-associated protein-interacting FFAT motif of CERT
-
Kawano, M.; Kumagai, K.; Nishijima, M.; Hanada, K., Efficient trafficking of ceramide from the endoplasmic reticulum to the Golgi apparatus requires a VAMP-associated protein-interacting FFAT motif of CERT. J Biol Chem, 2006, 281, (40), 30279-30288
-
(2006)
J Biol Chem
, vol.281
, Issue.40
, pp. 30279-30288
-
-
Kawano, M.1
Kumagai, K.2
Nishijima, M.3
Hanada, K.4
-
57
-
-
44449129087
-
Protein phosphatase 2Cepsilon is an endoplasmic reticulum integral membrane protein that dephosphorylates the ceramide transport protein CERT to enhance its association with organelle membranes
-
Saito, S.; Matsui, H.; Kawano, M.; Kumagai, K.; Tomishige, N.; Hanada, K.; Echigo, S.; Tamura, S.; Kobayashi, T., Protein phosphatase 2Cepsilon is an endoplasmic reticulum integral membrane protein that dephosphorylates the ceramide transport protein CERT to enhance its association with organelle membranes. J Biol Chem, 2008, 283, (10), 6584-6593
-
(2008)
J Biol Chem
, vol.283
, Issue.10
, pp. 6584-6593
-
-
Saito, S.1
Matsui, H.2
Kawano, M.3
Kumagai, K.4
Tomishige, N.5
Hanada, K.6
Echigo, S.7
Tamura, S.8
Kobayashi, T.9
-
58
-
-
63049110165
-
Casein kinase I{gamma}2 down-regulates trafficking of ceramide in the synthesis of sphingomyelin
-
Tomishige, N.; Kumagai, K.; Kusuda, J.; Nishijima, M.; Hanada, K., Casein kinase I{gamma}2 down-regulates trafficking of ceramide in the synthesis of sphingomyelin. Mol Biol Cell, 2009, 20, (1), 348-357
-
(2009)
Mol Biol Cell
, vol.20
, Issue.1
, pp. 348-357
-
-
Tomishige, N.1
Kumagai, K.2
Kusuda, J.3
Nishijima, M.4
Hanada, K.5
-
59
-
-
50649122795
-
Goodpasture antigen-binding protein and its spliced variant, ceramide transfer protein, have different functions in the modulation of apoptosis during zebrafish development
-
Granero-Molto, F.; Sarmah, S.; O'Rear, L.; Spagnoli, A.; Abrahamson, D.; Saus, J.; Hudson, B.G.; Knapik, E.W., Goodpasture antigen-binding protein and its spliced variant, ceramide transfer protein, have different functions in the modulation of apoptosis during zebrafish development. J Biol Chem, 2008, 283, (29), 20495-20504
-
(2008)
J Biol Chem
, vol.283
, Issue.29
, pp. 20495-20504
-
-
Granero-Molto, F.1
Sarmah, S.2
O'Rear, L.3
Spagnoli, A.4
Abrahamson, D.5
Saus, J.6
Hudson, B.G.7
Knapik, E.W.8
-
60
-
-
0026781889
-
Intracellular processes associated with glycoprotein transport and processing
-
Slomiany, A.; Grzelinska, E.; Grabska, M.; Yamaki, K.; Tamura, S.; Kasinathan, C.; Slomiany, B.L., Intracellular processes associated with glycoprotein transport and processing. Archives of biochemistry and biophysics, 1992, 298, (1), 167-175
-
(1992)
Archives of Biochemistry and Biophysics
, vol.298
, Issue.1
, pp. 167-175
-
-
Slomiany, A.1
Grzelinska, E.2
Grabska, M.3
Yamaki, K.4
Tamura, S.5
Kasinathan, C.6
Slomiany, B.L.7
-
61
-
-
67449147119
-
Sphingomyelin synthase-related protein SMSr controls ceramide homeostasis in the ER
-
Vacaru, A.M.; Tafesse, F.G.; Ternes, P.; Kondylis, V.; Hermansson, M.; Brouwers, J.F.; Somerharju, P.; Rabouille, C.; Holthuis, J.C., Sphingomyelin synthase-related protein SMSr controls ceramide homeostasis in the ER. J Cell Biol, 2009, 185, (6), 1013-1027
-
(2009)
J Cell Biol
, vol.185
, Issue.6
, pp. 1013-1027
-
-
Vacaru, A.M.1
Tafesse, F.G.2
Ternes, P.3
Kondylis, V.4
Hermansson, M.5
Brouwers, J.F.6
Somerharju, P.7
Rabouille, C.8
Holthuis, J.C.9
-
62
-
-
34249828179
-
Regulators of mitotic arrest and ceramide metabolism are determinants of sensitivity to paclitaxel and other chemotherapeutic drugs
-
Swanton, C.; Marani, M.; Pardo, O.; Warne, P.H.; Kelly, G.; Sahai, E.; Elustondo, F.; Chang, J.; Temple, J.; Ahmed, A.A.; Brenton, J.D.; Downward, J.; Nicke, B., Regulators of mitotic arrest and ceramide metabolism are determinants of sensitivity to paclitaxel and other chemotherapeutic drugs. Cancer Cell, 2007, 11, (6), 498-512
-
(2007)
Cancer Cell
, vol.11
, Issue.6
, pp. 498-512
-
-
Swanton, C.1
Marani, M.2
Pardo, O.3
Warne, P.H.4
Kelly, G.5
Sahai, E.6
Elustondo, F.7
Chang, J.8
Temple, J.9
Ahmed, A.A.10
Brenton, J.D.11
Downward, J.12
Nicke, B.13
-
63
-
-
0035079539
-
Ceramide glycosylation potentiates cellular multidrug resistance
-
Liu, Y.Y.; Han, T.Y.; Giuliano, A.E.; Cabot, M.C., Ceramide glycosylation potentiates cellular multidrug resistance. FASEB J, 2001, 15, (3), 719-730
-
(2001)
FASEB J
, vol.15
, Issue.3
, pp. 719-730
-
-
Liu, Y.Y.1
Han, T.Y.2
Giuliano, A.E.3
Cabot, M.C.4
-
64
-
-
18144371163
-
Glucosylceramide synthase blockade down-regulates P-glycoprotein and resensitizes multidrug-resistant breast cancer cells to anticancer drugs
-
Gouaze, V.; Liu, Y.Y.; Prickett, C.S.; Yu, J.Y.; Giuliano, A.E.; Cabot, M.C., Glucosylceramide synthase blockade down-regulates P-glycoprotein and resensitizes multidrug-resistant breast cancer cells to anticancer drugs. Cancer Res, 2005, 65, (9), 3861-3867
-
(2005)
Cancer Res
, vol.65
, Issue.9
, pp. 3861-3867
-
-
Gouaze, V.1
Liu, Y.Y.2
Prickett, C.S.3
Yu, J.Y.4
Giuliano, A.E.5
Cabot, M.C.6
-
65
-
-
77950341123
-
Assessment of an RNA interference screen-derived mitotic and ceramide pathway metagene as a predictor of response to neoadjuvant paclitaxel for primary triplenegative breast cancer: A retrospective analysis of five clinical trials
-
Juul, N.; Szallasi, Z.; Eklund, A.C.; Li, Q.; Burrell, R.A.; Gerlinger, M.; Valero, V.; Andreopoulou, E.; Esteva, F.J.; Symmans, W.F.; Desmedt, C.; Haibe-Kains, B.; Sotiriou, C.; Pusztai, L.; Swanton, C., Assessment of an RNA interference screen-derived mitotic and ceramide pathway metagene as a predictor of response to neoadjuvant paclitaxel for primary triplenegative breast cancer: a retrospective analysis of five clinical trials. Lancet Oncol, 2010, 11, (4), 358-365
-
(2010)
Lancet Oncol
, vol.11
, Issue.4
, pp. 358-365
-
-
Juul, N.1
Szallasi, Z.2
Eklund, A.C.3
Li, Q.4
Burrell, R.A.5
Gerlinger, M.6
Valero, V.7
Andreopoulou, E.8
Esteva, F.J.9
Symmans, W.F.10
Desmedt, C.11
Haibe-Kains, B.12
Sotiriou, C.13
Pusztai, L.14
Swanton, C.15
-
66
-
-
33749022800
-
Structural and functional features and significance of the physical linkage between ER and mitochondria
-
Csordas, G.; Renken, C.; Varnai, P.; Walter, L.; Weaver, D.; Buttle, K.F.; Balla, T.; Mannella, C.A.; Hajnoczky, G., Structural and functional features and significance of the physical linkage between ER and mitochondria. J Cell Biol, 2006, 174, (7), 915-921
-
(2006)
J Cell Biol
, vol.174
, Issue.7
, pp. 915-921
-
-
Csordas, G.1
Renken, C.2
Varnai, P.3
Walter, L.4
Weaver, D.5
Buttle, K.F.6
Balla, T.7
Mannella, C.A.8
Hajnoczky, G.9
-
67
-
-
77957560607
-
The BH3-only protein Bad confers breast cancer taxane sensitivity through a nonapoptotic mechanism
-
Craik, A.C.; Veldhoen, R.A.; Czernick, M.; Buckland, T.W.; Kyselytzia, K.; Ghosh, S.; Lai, R.; Damaraju, S.; Underhill, D.A.; Mackey, J.R.; Goping, I.S., The BH3-only protein Bad confers breast cancer taxane sensitivity through a nonapoptotic mechanism. Oncogene, 2010, 29, (39), 5381-5391
-
(2010)
Oncogene
, vol.29
, Issue.39
, pp. 5381-5391
-
-
Craik, A.C.1
Veldhoen, R.A.2
Czernick, M.3
Buckland, T.W.4
Kyselytzia, K.5
Ghosh, S.6
Lai, R.7
Damaraju, S.8
Underhill, D.A.9
Mackey, J.R.10
Goping, I.S.11
-
68
-
-
14944349359
-
Apoptosis of non-smallcell lung cancer cell lines after paclitaxel treatment involves the BH3-only proapoptotic protein Bim
-
Li, R.; Moudgil, T.; Ross, H.J.; Hu, H.M., Apoptosis of non-smallcell lung cancer cell lines after paclitaxel treatment involves the BH3-only proapoptotic protein Bim. Cell Death Differ, 2005, 12, (3), 292-303.
-
(2005)
Cell Death Differ
, vol.12
, Issue.3
, pp. 292-303
-
-
Li, R.1
Moudgil, T.2
Ross, H.J.3
Hu, H.M.4
|