Biomarkers as management tools for industries in the pork production chain

Journal on Chain and Network Science

Volumn 11, Issue 2, 2011, Pages 155-166

  Te Pas, Marinus ^a   Hoekman, Arend ^a   Smits, Mari ^a  

^a WAGENINGEN UNIVERSITY   (Netherlands)

Author keywords

biomarkers; chain management; omics technologies; pork production chain

Indexed keywords

EID: 80053989493     PISSN: 15691829     EISSN: 22244662     Source Type: Journal    
DOI: 10.3920/JCNS2011.Qpork6     Document Type: Article

References (58)

1. Aldwin, C.A. 2000. Stress, coping and development an integrative perspective. The Guilford Press, Guilford Publications Inc. New York, NY, USA, 441pp.
2. Bayol, S.A., B.H. Simbi and N.C. Stickland 2005. A maternal cafeteria diet during gestation and lactation promotes adiposity and impairs skeletal muscle development and metabolism in rat offspring at weaning. Journal of Physiology 567: 951-961.
3. Bendixen, E. 2005. The use of proteomics in meat science. Meat Science 71: 138-149.
4. Cagnazzo, M., M.F.W. Te Pas, J. Priem, A. de Wit, M.H. Pool, R. Davoli and V. Russo 2006. Comparison of prenatal muscle tissue expression profiles of two pig breeds differing in muscle characteristics. Journal of Animal Science 84: 1-10.
5. Calus, M.P.L. and R.F. Veerkamp 2007. Accuracy of breeding values when using and ignoring the polygenic effect in genomic breeding value estimation with a marker density of one SNP per cM. Journal of Animal Breeding and Genetics 124: 362-368.
6. Dalloul, R.A., J.A. Long, A.V. Zimin, L. Aslam, K. Beal, L. Ann Blomberg, P. Bouffard, D.W. Burt, O. Crasta, R.P. Crooijmans, K. Cooper, R.A. Coulombe, S. De, M.E. Delany, J.B. Dodgson, J.J. Dong, C. Evans, K.M. Frederickson, P. Flicek, L. Florea, O. Folkerts, M.A. Groenen, T.T. Harkins, J. Herrero, S. Hoffmann, H.J. Megens, A. Jiang, P. de Jong, P. Kaiser, H. Kim, K.W., Kim, S. Kim, D. Langenberger, M.K. Lee, T. Lee, S. Mane, G. Marcais, M. Marz, A.P. McElroy, T. Modise, M. Nefedov, C. Notredame, I.R. Paton, W.S. Payne, G. Pertea, D. Prickett, D. Puiu, D. Qioa, E. Raineri, M. Ruffier, S.L. Salzberg, M.C. Schatz, C. Scheuring, C.J. Schmidt, S. Schroeder, S.M. Searle, E.J. Smith, J. Smith, T.S. Sonstegard, P.F. Stadler, H. Tafer, Z.J. Tu, C.P. Van Tassell, A.J. Vilella, K.P. Williams, J.A. Yorke, L. Zhang, H.B. Zhang, X. Zhang, Y. Zhang and K.M. Reed, 2010. Multi-platform next-generation sequencing of the domestic turkey (Meleagris gallopavo): genome assembly and analysis. Public Library of Science Biology 8: e1000475 DOI:
7. Fossi, M.C., L. Marsili, M. Junin, H. Castello, J.A. Lorenzani, S. Casini, C. Savelli and C. Leonzio 1997. Use of nondestructive biomarkers and residue analysis to assess the health status of endangered species of pinnipeds in the south-west Atlantic. Marine Pollution Bulletin 34: 157-162.
8. Frost, R.A. and C.H. Lang 2008. Regulation of muscle growth by pathogen-associated molecules. Journal of Animal Science 86: E84-E93.
9. Fujii, J., K. Otsu, F, Zorzato, S. de Leon, V.K. Khanna, J.E. Weiler, P.J. O'Brien and D.H. MacLennan 1991. Identification of a mutation in porcine ryanodine receptor associated with malignant hyperthermia. Science 253: 448-451.
10. Gammeltoft, S. 1984. Insulin receptors: binding kinetics and structure-function relationship of insulin. Physiological Reviews 64: 1321-1378.
11. Goodsaid, F. and F. Frueh, 2007. Biomarker Qualification Pilot Process at the US Food and Drug Administration. American Association of Pharmaceutical Scientists Journal 9, Article 10 http://www.aapsj.org
12. Grandin, T. 1997. Assessment of stress during handling and transport. Journal of Animal Science 75: 249-257.
13. Gravett, M.G., M.J. Novy, R.G. Rosenfeld, A.P. Reddy, T. Jacob, M. Turner, A. McCormack, J.A. Lapidus, J., Hitti, D.A. Eschenbach, C.T. Roberts, Jr. and S.R. Nagalla 2004. Diagnosis of Intra-amniotic Infection by Proteomic Profiling and Identification of Novel Biomarkers. Journal of the American Medical Aaaociation 292: 462-469.
14. International Chicken Genome Sequencing Consortium (ICGSC) 2004. Sequence and comparative analysis of the chicken genome provide unique perspectives on vertebrate evolution. Nature 432: 695-716.
15. Jung, P. 2011. Product Biomonitoring and Responsible Reporting. Environ Health Perspectives 119: A58-A59.
16. Kaufmann, D., A. Hofer, J.P. Bidanel and N. Künzi 2000. Genetic parameters for individual birth and weaning weight and for litter size of Large White pigs. Journal of Animal Breeding and Genetics 117: 121-128.
17. Lander, E.S., et al 2001. Initial sequencing and analysis of the human genome. Nature 409: 860-921.
18. López, M.G., 2006. Authenticity: The case of tequila. In: Ebeler, S.E., G.R. Takeoka and P. Winterhalter (eds.) Authentication of food and wine, ACS Symposium Series, Vol. 952, Chapter 18, pp 273-287. Chapter DOI:
19. Lopez-Albors, O., M.D. Ayala, F. Gil, A. Garcia-Alcazar, E. Abellan, R. Latorre, G. Ramirez-Zarzosa and J.M. Vazquez 2003. Early temperature effects on muscle growth dynamics and histochemical profile of muscle fibres of sea bass Dicentrarchus labrax L., during larval and juvenile stages. Aquaculture 220: 385-406.
20. Madec, F., R. Geers, P. Vesseur, N. Kjeldsen and T. Blaha 2001. Traceability in the pig production chain. Scientific and Technical Review International Office of Eoizootics 20: 523-537.
21. Meuwissen, T.H.E. and M.E. Goddard 1996. The use of marker haplotypes in animal breeding schemes. Genetics Selection Evolution 28: 161-176.
22. Middelbos, I.S., B.M. Vester, L.K. Karr-Lilienthal, L.B. Schook and K.S. Swanson, 2009. Age and diet affect gene expression profile in canine skeletal muscle. Public Library of Science ONE 4: e4481. doi:
23. Moffat, B.A., T.L. Chenevert, C.R. Meyer, P.E. Mckeever, D.E. Hall, B.A., Hoff, T.D. Johnson, A. Rehemtulla and B.D. Ross 2006. The functional diffusion map: an imaging biomarker for the early prediction of cancer treatment outcome. Neoplasia, 8: 259-267.
24. Moore, M.N., J.I. Allen and A. McVeigh 2006. Environmental prognostics: an integrated model supporting lysosomal stress responses as predictive biomarkers of animal health status. Marine Environmental Research 61: 278-304.
25. Moore, R.E., J. Kirwan, M.K. Doherty and P.D. Whitfield 2007. Biomarker discovery in animal health and disease: the application of post-genomic technologies biomarker insights 2: 185-196.
26. Mullen, A.M., P.C. Stapleton, D. Corcoran, R.M. Hamill, and A. White 2006. Understanding meat quality through the application of genomic and proteomic approaches. Meat Science 74: 3-16.
27. Nagahata, H. 2004. Bovine leukocyte adhesion deficiency: a review. The Journal of Veterinary Medical Science/the Japanese Society of Veterinary Science 66: 1475-1482.
28. Nass, S.J. and B. Stillman 2003. Large-scale biomedical science: exploring strategies for future research. National Academies Press, Washington, DC, USA.
29. Nebel, R.L., W.D. Whittier, B.G. Cassell and J.H. Britt 1987. Comparison of on-farm and laboratory milk progesterone assays for identifying errors in detection of estrus and diagnosis of pregnancy. Journal of Dairy Science 70: 1471-1476.
30. Pérez, M.P., J. Palacio, M.P. Santolaria, M.C. Acena, G. Chalcón, J.H. Calvo, P. Zaragoza, J.A. Beltran and S. García-Belenguer 2002. Effect of transport time on welfare and meat quality in pigs. Meat Science 61: 425-433.
31. Phillips, D.I.W., P.M. Clark, C.N. Hales and C. Osmond 1994. Understanding oral glucose tolerance: comparison of glucose or insulin measurements during the oral glucose tolerance test with specific measurements of insulin resistance and insulin secretion. Diabetic Medicine 11: 286-292.
32. Primrose, S., M. Woolfe and S. Rollinson 2010. Food forensics: methods for determining the authenticity of foodstuffs. Trends in Food Science & Technology 21: 582-590.
33. Reggiani, C. and F. Mascarello 2004. Fibre type identification and functional characterization in adult livestock animals. In: Te Pas, M.F.W., M.E. Everts and H.P. Haagsman (eds.) Muscle development of livestock animals - physiology, genetics, and meat quality. CABI publishers, Wallingford, Oxfordshire, UK, p 39-68.
34. Rehfeldt, C., I. Adamovic and G. Kuhn 2007. Effects of dietary daidzein supplementation of pregnant sows on carcass and meat quality and skeletal muscle cellularity of the progeny Meat Science 75: 103-111.
35. Rehfeldt, C., I. Fiedler and N.C. Stickland 2004. Number and size of muscle fibres in relation to meat production. In: Te Pas, M.F.W., M.E. Everts and H.P. Haagsman (eds.) Muscle development of livestock animals - physiology, genetics, and meat quality. CABI publishers, Wallingford, Oxfordshire, UK, p 1-38.
36. Sandercock, D.A., R.R. Hunter, G.R. Nute, M.A. Mitchell and P.M. Hocking 2001. Acute heat stress-induced alterations in blood acid-base status and skeletal muscle membrane integrity in broiler chickens at two ages: implications for meat quality. Poultry Science 80: 418-425.
37. Schokker, D., A.J.W. Hoekman, M.A. Smits and J.M.J. Rebel 2009. Gene expression patterns associated with chicken jejunal development. Developmental & Comparative Immunology 33: 1156-1164.
38. Sellier, P. and G. Monin 1994. Genetics of pig meat quality: a review. Journal of Muscle Foods 5: 187-219.
39. Shrivastava, S. and D. Dash, 2009. Applying nanotechnology to human health: revolution in biomedical sciences. Journal of Nanotechnology, Volume 2009, Article ID 184702, 14 pages. doi:
40. Stickland, N.C., S. Bayol, C. Ashton and C. Rehfeldt 2004. Manipulation of muscle fibre number during prenatal development. In: Te Pas, M.F.W., M.E. Everts and H.P. Haagsman (eds.) Muscle development of livestock animals - physiology, genetics, and meat quality. CABI publishers, Wallingford, Oxfordshire, UK, p 69-82.
41. Swanson, B.N. 2002. Delivery of high-quality biomarker assays. Disease Markers 18: 47-56.
42. Te Pas, M.F.W. and A.J.W. Hoekman 2011. Developing biomarkers to improve, detect and monitor high pork quality. In: Pork nutrition and health, Nova Publishers, Hauppauge, New York, USA, in press.
43. Te Pas, M.F.W. and A.Soumillion 2001. The use of physiologic and functional genomic information of the regulation of the determination of skeletal muscle mass in livestock breeding strategies to enhance meat production. Current Genomics 2: 285-304.
44. Te Pas, M.F.W., A. De Wit, J. Priem, M. Cagnazzo, R. Davoli, V. Russo and M.H. Pool 2005. Transcriptome expression profiles in prenatal pigs in relation to myogenesis. Journal of Muscle Research and Cell Motility 26: 157-165.
45. Te Pas, M.F.W., A. Soumillion, F.L. Harders, F.J. Verburg, T.J. Van den Bosch, P. Galesloot and T.H.E. Meuwissen 1999. Influences of myogenin genotype on birth weight, growth rate, carcass weight, backfat thickness and lean weight of pigs. Journal of Animal Science 77: 2352-2356.
46. Te Pas, M.F.W., E. Keuning, B. Hulsegge, A.H. Hoving-Bolink, G. Evans and H.A. Mulder 2010. Longissimus muscle transcriptome profiles related to carcass and meat quality traits in fresh meat Pietrain carcasses. Journal of Animal Science 88: 4044-4055.
47. Te Pas, M.F.W., E. Keuning, D.J.M. Van de Wiel, J.F. Young, N. Oksbjerg and L. Kruijt 2011. Proteome profiles of Longissimus and Biceps femoris porcine muscles related to exercise and resting. Journal of Life Science, in press.
48. Te Pas, M.F.W., I. Hulsegge and M.H. Pool 2007a. Pathway analysis: combining microarray data and physiological data to study myogenesis. Archiv Tierzucht/Archives Animal Breeding, Dummerstorf, special issue 50: 27-31.
49. Te Pas, M.F.W., I. Hulsegge, M.H. Pool, A. Coster, H.H. Heuven and L.L.G. Janss 2007b. Biochemical pathways analysis of microarray results: regulation of myogenesis. BMC Developmental Biology 7 doi:
50. Te Pas, M.F.W., J. Jansen, K.C.J.A. Broekman, H. Reimert and H.C.M. Heuven 2008. Post mortem proteome degradation profiles of longissimus muscle in Yorkshire and Duroc. Archiv Tierzucht/Archives Animal Breeding, Dummerstorf, 51: 62-68.
51. Te Pas, M.F.W., J. Jansen, K.C.J.A. Broekman, H. Reimert and H.C.M. Heuven 2009. Post mortem proteome degradation profiles of longissimus muscle in Yorkshire and Duroc pigs and its relationship with pork quality traits. Meat Science 83: 744-751.
52. Te Pas, M.F.W., M.H. Pool, I. Hulsegge and L.L.G. Janss 2006. Analysis of the differential transcriptome expression profiles during prenatal muscle tissue development. Archiv Tierzucht/Archives Animal Breeding, Dummerstorf, special issue 49: 110-115.
53. Tisch, R. and H. McDevitt 1996. Insulin dependent diabetes mellitus. Cell 85: 291-297.
54. Van Woldragen, M., P. Balk, R. Hall, M. Nijenhuis, H. Van den Broeck, O. Vorst and A. Poelman 2003. Applied genomics: an innovative tool to improve quality in chains: predicting mealiness in apples: a case study: proceedings of the international conference on quality in chains: an integrated view on fruit and vegetable quality. Acta horticulturae 1: 387-394.
55. Warriss, P.D., S.N. Brown, J.E. Edwards, M.H. Anil and D.P. Fordham 1992. Time in lairage needed by pigs to recover from the stress of transport. Veterinary Record 131: 194-196.
56. Wilkes, D., S.Q. Xie, N.C. Stickland, H. Alami-Durante, M. Kentouri, A. Sterioti, G. Koumoundouros, B. Fauconneau and G. Goldspink 2001. Temperature and myogenic factor transcript levels during early development determines muscle growth potential in rainbow trout (Oncorhynchus mykiss) and sea bass (Dicentrarchus labrax). Journal of Experimental Biology 204: 2763-2771.
57. Wilson, K.J. and E. De la Vega 2005. The potential of microarrays to assist shrimp breeding and production: a review. Australian Journal of Experimental Agriculture 45: 901-911.
58. Wood, J.D., G.R. Nute, R.I. Richardson, F.M. Whittington, O. Southwood, G. Plastow, R. Mansbridge, N. Da Costa and K.C. Chang 2004. Effects of breed, diet and muscle on fat deposition and eating quality in pigs. Meat Science 67: 651-667.