Docking and free energy simulations to predict conformational domains involved in hCG-LH receptor interactions using recombinant antibodies

Proteins: Structure, Function and Bioinformatics

Volumn 79, Issue 11, 2011, Pages 3108-3122

  Majumdar, Ritankar ^a   Railkar, Reema ^a   Dighe, Rajan R ^a  

^a INDIAN INSTITUTE OF SCIENCE   (India)

Author keywords

Association dissociation kinetics; Glycoprotein hormones; GPCR; MM PBSA; Molecular dynamics; Phage display; Residue contact; ScFv modeling

Indexed keywords

CHORIONIC GONADOTROPIN; LUTEINIZING HORMONE RECEPTOR; SINGLE CHAIN FRAGMENT VARIABLE ANTIBODY;

ARTICLE; CONFORMATION; CRYSTAL STRUCTURE; ENZYME LINKED IMMUNOSORBENT ASSAY; EPITOPE MAPPING; HORMONE RECEPTOR INTERACTION; HUMAN; HUMAN CELL; IN VITRO STUDY; MOLECULAR DOCKING; MOLECULAR DYNAMICS; MOLECULAR MECHANICS; PRIORITY JOURNAL; SEQUENCE ANALYSIS; SIMULATION;

AMINO ACID SEQUENCE; ANTIGEN-ANTIBODY REACTIONS; CHORIONIC GONADOTROPIN; COMPUTER SIMULATION; EPITOPE MAPPING; EPITOPES; HUMANS; KINETICS; MOLECULAR DYNAMICS SIMULATION; PEPTIDE LIBRARY; RECEPTORS, LH; RECOMBINANT PROTEINS; SINGLE-CHAIN ANTIBODIES;

RUMEX;

EID: 80053970782     PISSN: 08873585     EISSN: 10970134     Source Type: Journal    
DOI: 10.1002/prot.23138     Document Type: Article

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