Raptor and rheb negatively regulate skeletal myogenesis through suppression of insulin receptor substrate 1 (IRS1)

Journal of Biological Chemistry

Volumn 286, Issue 41, 2011, Pages 35675-35682

  Ge, Yejing ^a   Yoon, Mee Sup ^a   Chen, Jie ^a  

^a UNIVERSITY OF ILLINOIS AT URBANA CHAMPAIGN   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AKT ACTIVATION; CELLULAR PATHWAY; INSULIN RECEPTOR SUBSTRATE-1; MAMMALIAN TARGET OF RAPAMYCIN (MTOR); MTOR SIGNALING; MYOBLASTS; MYOGENESIS; OVER-EXPRESSION; PROTEIN LEVEL; SIGNALING COMPONENTS; SIGNALING MECHANISMS; SKELETAL MYOGENESIS;

ACTIVATION ANALYSIS; MAMMALS; PHOSPHORYLATION; SIGNALING;

ANTIBIOTICS;

INSULIN RECEPTOR SUBSTRATE 1; MAMMALIAN TARGET OF RAPAMYCIN; MAMMALIAN TARGET OF RAPAMYCIN COMPLEX 1; PROTEIN KINASE B; RAPTOR PROTEIN; REGULATOR PROTEIN; RHEB PROTEIN; S6 KINASE; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CELL DIFFERENTIATION; CONTROLLED STUDY; MOUSE; MUSCLE DEVELOPMENT; MYOBLAST; NONHUMAN; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; REGULATORY MECHANISM; SIGNAL TRANSDUCTION; SKELETAL MUSCLE;

ANIMALS; CARRIER PROTEINS; CELL DIFFERENTIATION; CELL LINE; GENE KNOCKDOWN TECHNIQUES; HUMANS; INSULIN RECEPTOR SUBSTRATE PROTEINS; MICE; MONOMERIC GTP-BINDING PROTEINS; MUSCLE DEVELOPMENT; MUSCLE, SKELETAL; MYOBLASTS, SKELETAL; NEUROPEPTIDES; PHOSPHATIDYLINOSITOL 3-KINASES; PHOSPHORYLATION; PROTO-ONCOGENE PROTEINS C-AKT; RIBOSOMAL PROTEIN S6 KINASES, 90-KDA; SIGNAL TRANSDUCTION; TOR SERINE-THREONINE KINASES;

MAMMALIA; RAPTORES;

EID: 80053926886     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M111.262881     Document Type: Article

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