Aβ-related angiitis: Primary angiitis of the central nervous system associated with cerebral amyloid angiopathy

Brain

Volumn 128, Issue 3, 2005, Pages 500-515

  Scolding, Neil J ^a   Joseph, Fady ^a   Kirby, Patricia A ^h   Mazanti, Ingrid ^b   Gray, Françoise ⁱ   Mikol, Jacqueline ⁱ   Ellison, David ^c   Hilton, David A ^e   Williams, Timothy L ^d   MacKenzie, James M ^f   Xuereb, John H ^g   Love, Seth ^a,j  

^a UNIVERSITY OF BRISTOL   (United Kingdom)

^b SOUTHAMPTON GENERAL HOSPITAL   (United Kingdom)

^c NEWCASTLE GENERAL HOSPITAL   (United Kingdom)

^d ROYAL VICTORIA INFIRMARY   (United Kingdom)

^e DERRIFORD HOSPITAL   (United Kingdom)

^f ABERDEEN ROYAL INFIRMARY   (United Kingdom)

^g CAMBRIDGE UNIVERSITY HOSPITALS NHS FOUNDATION TRUST   (United Kingdom)

^h UNIVERSITY OF IOWA   (United States)

ⁱ HÔPITAL LARIBOISIÈRE   (France)

^j FRENCHAY HOSPITAL   (United Kingdom)

more..

Author keywords

A related angiitis; Alzheimer's disease; Cerebral amyloid angiopathy; CNS vasculitis; Primary angiitis of the CNS

Indexed keywords

ACICLOVIR; AMYLOID BETA PROTEIN; AZATHIOPRINE; CYCLOPHOSPHAMIDE; DEXAMETHASONE; HEPARIN; IMMUNOGLOBULIN; PREDNISOLONE; STEROID;

ADULT; AGED; ALZHEIMER DISEASE; AMYLOID BETA ANGIITIS; ARTICLE; BRAIN ANGIOGRAPHY; BRAIN CORTEX; BRAIN VASCULITIS; CENTRAL NERVOUS SYSTEM; CEREBROSPINAL FLUID EXAMINATION; CLINICAL ARTICLE; CLINICAL FEATURE; COMPUTER ASSISTED TOMOGRAPHY; FEMALE; GRANULOMATOUS INFLAMMATION; HALLUCINATION; HUMAN; HUMAN TISSUE; IMMUNIZATION; INFLAMMATION; LYMPHOMATOSIS; MALE; MENTAL HEALTH; MICROGLIA; NEUROIMAGING; NEUROPATHOLOGY; NUCLEAR MAGNETIC RESONANCE IMAGING; ONSET AGE; PRIMARY ANGIITIS OF THE CENTRAL NERVOUS SYSTEM; PRIORITY JOURNAL; VASCULAR AMYLOIDOSIS; CASE REPORT; ELECTROENCEPHALOGRAPHY; MIDDLE AGED; PROGNOSIS; TREATMENT OUTCOME;

AGED; AGED, 80 AND OVER; AMYLOID BETA-PROTEIN; CEREBRAL AMYLOID ANGIOPATHY; CEREBRAL ANGIOGRAPHY; ELECTROENCEPHALOGRAPHY; FEMALE; HUMANS; MAGNETIC RESONANCE IMAGING; MALE; MIDDLE AGED; PROGNOSIS; TOMOGRAPHY, X-RAY COMPUTED; TREATMENT OUTCOME; VASCULITIS, CENTRAL NERVOUS SYSTEM;

EID: 20144366048     PISSN: 00068950     EISSN: None     Source Type: Journal    
DOI: 10.1093/brain/awh379     Document Type: Article

References (60)

1. Ahluwalia N, Vellas B. Immunologic and inflammatory mediators and cognitive decline in Alzheimer's disease. Immunol Allergy Clin North Am 2003; 23: 103-15.
2. Alrawi A, Trobe J, Blaivas M, Musch DC. Brain biopsy in primary angiitis of the central nervous system. Neurology 1999; 53; 858-60.
3. Anders KH, Wang ZZ, Kornfeld M, Gray F, Soontornniyomkij V, Reed LA, et al. Giant cell arteritis in association with cerebral amyloid angiopathy: immunohistochemical and molecular studies. Hum Pathol 1997; 28: 1237-46.
4. Anon. Case records of the Massachusetts General Hospital. Weekly clinico-pathological exercises. Case 10-2000. A 63-year-old man with changes in behavior and ataxia. N Engl J Med 2000; 342: 957-65.
5. Bard F, Cannon C, Barbour R, Burke RL, Games D, Grajeda H, et al. Peripherally administered antibodies against amyloid β-peptide enter the central nervous system and reduce pathology in a mouse model of Alzheimer disease. Nat Med 2000; 6: 916-9.
6. Briceno CE, Resch L, Bernstein M. Cerebral amyloid angiopathy presenting as a mass lesion. Stroke 1987; 18: 234-9.
7. Brotman DJ, Eberhart CG, Burger PC, McArthur JC, Hellmann DB. Primary angiitis of the central nervous system and Alzheimer's disease: clinically and pathologically evident in a single patient. J Rheumatol 2000; 27: 2935-7.
8. Calabrese LH, Mallek JA. Primary angiitis of the central nervous system. Report of 8 new cases, review of the literature, and proposal for diagnostic criteria. Medicine 1988; 67: 20-39.
9. Cadavid D, Mena H, Koeller K, Frommelt RA. Cerebral β amyloid angiopathy is a risk factor for cerebral ischemic infarction. A case control study in human brain biopsies. J Neuropathol Exp Neurol 2000; 59: 768-73.
10. Chalmers K, Wilcock GK, Love S. APOE ε4 influences the pathological phenotype of Alzheimer's disease by favouring cerebrovascular over parenchymal accumulation of Aβ protein. Neuropathol Appl Neurobiol 2003; 29: 231-8.
11. Check E. Nerve inflammation halts trial for Alzheimer's drug. Nature 2002; 415: 462.
12. Das P, Howard V, Loosbrock N, Dickson D, Murphy MP, Golde TE. Amyloid-β immunization effectively reduces amyloid deposition in FcRγ-/- knock-out mice. J Neurosci 2003; 23: 8532-8.
13. Eng JA, Frosch MP, Choi K, Rebeck GW, Greenberg SM. Clinical manifestations of cerebral amyloid angiopathy-related inflammation. Ann Neurol 2004; 55: 250-6.
14. Esiri MM, Wilcock GK. Cerebral amyloid angiopathy in dementia and old age. J Neurol Neurosurg Psychiatry 1986; 49: 1221-6.
15. Ferrer I, Boada RM, Sanchez Guerra ML, Rey MJ, Costa-Jussa F. Neuropathology and pathogenesis of encephalitis following amyloid-beta immunization in Alzheimer's disease. Brain Pathol 2004; 14: 11-20.
16. Fountain NB, Eberhard DA. Primary angiitis of the central nervous system associated with cerebral amyloid angiopathy: report of two cases and review of the literature. Neurology 1996; 46: 190-7.
17. Fountain NB, Lopes MB. Control of primary angiitis of the CNS associated with cerebral amyloid angiopathy by cyclophosphamide alone. Neurology 1999; 52: 660-2.
18. Gilles C, Brucher JM, Khoubesserian P, Vanderhaeghen JJ. Cerebral amyloid angiopathy as a cause of multiple intracerebral hemorrhages. Neurology 1984; 34: 730-5.
19. Ginsberg L, Geddes J, Valentine A. Amyloid angiopathy and granulomatous angiitis of the central nervous system: a case responding to corticosteroid treatment. J Neurol 1988; 235: 438-40.
20. Gray F, Dubas F, Roullet E, Escourolle R. Leukoencephalopathy in diffuse hemorrhagic cerebral amyloid angiopathy. Ann Neurol 1985; 18: 54-9.
21. Gray F, Vinters HV, Le NH, Salama J, Delaporte P, Poirier J. Cerebral amyloid angiopathy and granulomatous angiitis: immunohistochemical study using antibodies to the Alzheimer A4 peptide. Hum Pathol 1990; 21: 1290-3.
22. Greenberg SM, Vonsattel JP, Stakes JW, Gruber M, Finklestein SP. The clinical spectrum of cerebral amyloid angiopathy: presentations without lobar hemorrhage. Neurology 1993; 43: 2073-9.
23. Hankey G. Isolated angiitis/angiopathy of the CNS. Prospective diagnostic and therapeutic experience. Cerebrovasc Dis 1991; 1: 2-15.
24. Harkness KA, Coles A, Pohl U, Xuereb JH, Baron JC, Lennox GG. Rapidly reversible dementia in cerebral amyloid inflammatory vasculopathy. Eur J Neurol 2004; 11: 59-62.
25. Imaoka K, Kobayashi S, Fujihara S, Shimode K, Nagasaki M. Leukoencephalopathy with cerebral amyloid angiopathy: a semiquantitative and morphometric study. J Neurol 1999; 246: 661-6.
26. Jacobs DA, Liu GT, Nelson PT, Galetta SL. Primary central nervous system angiitis, amyloid angiopathy, and Alzheimer's pathology presenting with Balint's syndrome. Surv Ophthalmol 2004; 49: 454-9.
27. Janus C, Pearson J, McLaurin J, Mathews PM, Jiang Y, Schmidt SD, et al. Aβ peptide immunization reduces behavioural impairment and plaques in a model of Alzheimer's disease. Nature 2000; 408: 979-82.
28. Joseph FG, Scolding NJ. Cerebral vasculitis-a practical approach. Pract Neurol 2002; 2: 80-93.
29. Le Cos P, Mikol J, Ferrand J, Woimant F, Masters C, Beyreuther K, et al. Granulomatous angiitis and cerebral amyloid angiopathy presenting as a mass lesion. Neuropathol Appl Neurobiol 1991; 17: 149-55.
30. Lie JT. Primary (granulomatous) angiitis of the central nervous system: a clinicopathologic analysis of 15 new cases and a review of the literature. Hum Pathol 1992; 23: 164-71.
31. Lombardo JA, Stern EA, McLellan ME, Kajdasz ST, Hickey GA, Bacskai BJ, et al. Amyloid-β antibody treatment leads to rapid normalization of plaque-induced neuritic alterations. J Neurosci 2003; 23: 10879-83.
32. Love S. Contribution of cerebral amyloid angiopathy to Alzheimer's disease. J Neurol Neurosurg Psychiatry 2004; 75: 1-4.
33. Love S, Nicoll JA, Hughes A, Wilcock GK. APOE and cerebral amyloid angiopathy in the elderly. Neuroreport 2003; 14: 1535-6.
34. Mandybur TI. Cerebral amyloid angiopathy: the vascular pathology and complications. J Neuropathol Exp Neurol 1986; 45: 79-90.
35. Mandybur TI, Balko G. Cerebral amyloid angiopathy with granulomatous angiitis ameliorated by steroid-cytoxan treatment. Clin Neuropharmacol 1992; 15: 241-7.
36. McGeer EG, McGeer PL. Inflammatory processes in Alzheimer's disease. Prog Neuropsychopharmacol Biol Psychiatry 2003; 27: 741-9.
37. Morgan D, Diamond DM, Gottschall PE, Ugen KE, Dickey C, Hardy J, et al. Aβ peptide vaccination prevents memory loss in an animal model of Alzheimer's disease. Nature 2000; 408: 982-5.
38. Murphy MN, Sima AA. Cerebral amyloid angiopathy associated with giant cell arteritis: a case report. Stroke 1985; 16: 514-7.
39. Nicoll JA, Wilkinson D, Holmes C, Steart P, Markham H, Weller RO. Neuropathology of human Alzheimer disease after immunization with amyloid-β peptide: a case report. Nat Med 2003; 9: 448-52.
40. Olichney JM, Hansen LA, Lee JH, Hofstetter CR, Katzman R, Thai LJ. Relationship between severe amyloid angiopathy, apolipoprotein E genotype, and vascular lesions in Alzheimer's disease. Ann N Y Acad Sci 2000; 903: 138-43.
41. Okazaki H, Reagan TJ, Campbell RJ. Clinicopathologic studies of primary cerebral amyloid angiopathy. Mayo Clin Proc 1979; 54: 22-31.
42. Orgogozo JM, Gilman S, Dartigues JF, Laurent B, Puel M, Kirby LC, et al. Subacute meningoencephalitis in a subset of patients with AD after Aβ42 immunization. Neurology 2003; 61: 46-54.
43. Powers JM, Stein BM, Torres RA. Sporadic cerebral amyloid angiopathy with giant cell reaction. Acta Neuropathol (Berl) 1990; 81: 95-8.
44. Probst A, Ulrich J. Amyloid angiopathy combined with granulomatous angiitis of the central nervous system: report on two patients. Clin Neuropathol 1985; 4: 250-9.
45. Reid AH, Maloney AF. Giant cell arteritis and arteriolitis associated with amyloid angiopathy in an elderly mongol. Acta Neuropathol (Berl) 1974; 27: 131-7.
46. Ringheim GE, Conant K. Neurodegenerative disease and the neuroimmune axis (Alzheimer's and Parkinson's disease, and viral infections). J Neuroimmunol 2004; 147: 43-9.
47. Schenk D. Amyloid-β immunotherapy for Alzheimer's disease: the end of the beginning. Nat Rev Neurosci 2002; 3: 824-8.
48. Schenk D, Barbour R, Dunn W, Gordon G, Grajeda H, Guido T, et al. Immunization with amyloid-β attenuates Alzheimer-disease-like pathology in the PDAPP mouse. Nature 1999; 400: 173-7.
49. Schmidley JW. Central and peripheral nervous system angiitis. Oxford: Butterworth Heinemann; 2000.
50. Schwab P, Lidov HG, Schwartz RB, Anderson RJ. Cerebral amyloid angiopathy associated with primary angiitis of the central nervous system: report of 2 cases and review of the literature. Arthritis Rheum 2003; 49: 421-7.
51. Scolding NJ, Jayne DR, Zajicek JP, Meyer PAR, Wraight EP, Lockwood CM. The syndrome of cerebral vasculitis: recognition, diagnosis and management. Q J Med 1997; 90: 61-73.
52. Shintaku M, Osawa K, Toki J, Maeda R, Nishiyama T. A case of granulomatous angiitis of the central nervous system associated with amyloid angiopathy. Acta Neuropathol (Berl) 1986; 70: 340-2.
53. Sigurdsson EM, Scholtzova H, Mehta PD, Frangione B, Wisniewski T. Immunization with a nontoxic/nonfibrillar amyloid-β homologous peptide reduces Alzheimer's disease-associated pathology in transgenic mice. Am J Pathol 2001; 159: 439-47.
54. Streichenberger N, Girard-Madoux P, Verejan I, Pialat J, Vital C, Kopp N. Giant cell angiitis of the central nervous system with amyloid angiopathy. A case report and review of the literature. Clin Exp Pathol 1999; 47: 311-7.
55. Suo Z, Tan J, Placzek A, Crawford F, Fang C, Mullan M. Alzheimer's β-amyloid peptides induce inflammatory cascade in human vascular cells: the roles of cytokines and CD40. Brain Res 1998; 807: 110-7.
56. Tamargo RJ, Connolly ES Jr, McKhann GM, Khandji A, Chang Y, Libien J, et al. Clinicopathological review: primary angiitis of the central nervous system in association with cerebral amyloid angiopathy. Neurosurgery 2003; 53: 136-43.
57. Uchihara T, Akiyama H, Kondo H, Ikeda K. Activated microglial cells are colocalized with perivascular deposits of amyloid-beta protein in Alzheimer's disease brain. Stroke 1997; 28: 1948-50.
58. Vinters HV, Gilbert JJ. Cerebral amyloid angiopathy: incidence and complications in the aging brain. II. The distribution of amyloid vascular changes. Stroke 1983; 14: 924-8.
59. Yamada M, Tsukagoshi H, Otomo E, Hayakawa M. Cerebral amyloid angiopathy in the aged. J Neurol 1987; 234: 371-6.
60. Yamada M, Itoh Y, Shintaku M, Kawamura J, Jensson O, Thorsteinsson L, et al. Immune reactions associated with cerebral amyloid angiopathy. Stroke 1996; 27: 1155-62.