Concurrent hippocampal induction of MHC II pathway components and glial activation with advanced aging is not correlated with cognitive impairment

Journal of Neuroinflammation

Volumn 8, Issue , 2011, Pages

  VanGuilder, Heather D ^a   Bixler, Georgina V ^a   Brucklacher, Robert M ^a   Farley, Julie A ^b   Yan, Han ^b   Warrington, Junie P ^b   Sonntag, William E ^b   Freeman, Willard M ^a  

^a PENN STATE COLLEGE OF MEDICINE   (United States)

^b UNIVERSITY OF ARKANSAS FOR MEDICAL SCIENCES   (United States)

Author keywords

Aging; Cognitive decline; Hippocampus; Morris water maze; Neuroinflammation; Para inflammation

Indexed keywords

BIOLOGICAL MARKER; CD74 ANTIGEN; COMPLEMENT; GLIAL FIBRILLARY ACIDIC PROTEIN; IBA1 PROTEIN; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 2; TOLL LIKE RECEPTOR; UNCLASSIFIED DRUG; HLA ANTIGEN CLASS 2; TRANSCRIPTOME;

ADULT ANIMAL; AGED; AGING; ANIMAL EXPERIMENT; ANIMAL TISSUE; ANTIGEN PRESENTATION; ARTICLE; ASTROCYTE; BRAIN SYNAPTOSOME; CELL ACTIVATION; COGNITIVE DEFECT; CONTROLLED STUDY; DENTATE GYRUS; GENE; GENE EXPRESSION; GLIA CELL; HIPPOCAMPAL CA1 REGION; HIPPOCAMPAL CA3 REGION; HIPPOCAMPUS; IMMUNOHISTOCHEMISTRY; LEARNING; MALE; MAZE TEST; NERVOUS SYSTEM INFLAMMATION; NONHUMAN; POLYMERASE CHAIN REACTION; PROTEIN EXPRESSION; RAT; SPATIAL MEMORY; TRANSCRIPTOMICS; UPREGULATION; ANIMAL; ANIMAL BEHAVIOR; CYTOLOGY; FISCHER 344 RAT; GENE EXPRESSION PROFILING; GLIA; HUMAN; IMMUNOLOGY; MAJOR HISTOCOMPATIBILITY COMPLEX; METABOLISM; MICROARRAY ANALYSIS; PATHOPHYSIOLOGY; PHYSIOLOGY; PSYCHOLOGICAL ASPECT;

AGING; ANIMALS; BEHAVIOR, ANIMAL; BIOLOGICAL MARKERS; COGNITION DISORDERS; GENE EXPRESSION PROFILING; GENES, MHC CLASS II; HIPPOCAMPUS; HISTOCOMPATIBILITY ANTIGENS CLASS II; HUMANS; MAJOR HISTOCOMPATIBILITY COMPLEX; MALE; MAZE LEARNING; MICROARRAY ANALYSIS; NEUROGLIA; RATS; RATS, INBRED F344; TRANSCRIPTOME;

EID: 80053629791     PISSN: None     EISSN: 17422094     Source Type: Journal    
DOI: 10.1186/1742-2094-8-138     Document Type: Article

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