메뉴 건너뛰기




Volumn 98, Issue 2, 2007, Pages 594-601

Aging effects on the limits and stability of long-term synaptic potentiation and depression in rat hippocampal area CA1

Author keywords

[No Author keywords available]

Indexed keywords

AGING; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; ELECTROPHYSIOLOGY; HIPPOCAMPUS; LONG TERM DEPRESSION; LONG TERM POTENTIATION; MALE; NERVE CELL PLASTICITY; NERVE STIMULATION; NONHUMAN; PRIORITY JOURNAL; RAT; SYNAPTIC POTENTIAL; SYNAPTIC TRANSMISSION;

EID: 34547744428     PISSN: 00223077     EISSN: 15221598     Source Type: Journal    
DOI: 10.1152/jn.00249.2007     Document Type: Article
Times cited : (63)

References (63)
  • 1
    • 0033609045 scopus 로고    scopus 로고
    • Age-related defects in spatial memory are correlated with defects in the late phase of hippocampal long-term potentiation in vitro and are attenuated by drugs that enhance the cAMP signaling pathway
    • Bach ME, Barad M, Son H, Zhuo M, Lu YF, Shih R, Mansuy I, Hawkins RD, Kandel ER. Age-related defects in spatial memory are correlated with defects in the late phase of hippocampal long-term potentiation in vitro and are attenuated by drugs that enhance the cAMP signaling pathway. Proc Natl Acad Sci USA 96: 5280-5285, 1999.
    • (1999) Proc Natl Acad Sci USA , vol.96 , pp. 5280-5285
    • Bach, M.E.1    Barad, M.2    Son, H.3    Zhuo, M.4    Lu, Y.F.5    Shih, R.6    Mansuy, I.7    Hawkins, R.D.8    Kandel, E.R.9
  • 2
    • 0018344553 scopus 로고
    • Memory deficits associated with senescence: A neurophysiological and behavioral study in the rat
    • Barnes CA. Memory deficits associated with senescence: a neurophysiological and behavioral study in the rat. J Comp Physiol Psychol 93: 74-104, 1979.
    • (1979) J Comp Physiol Psychol , vol.93 , pp. 74-104
    • Barnes, C.A.1
  • 3
    • 0022403407 scopus 로고
    • An age comparison of the rates of acquisition and forgetting of spatial information in relation to long-term enhancement of hippocampal synapses
    • Barnes CA, McNaughton BL. An age comparison of the rates of acquisition and forgetting of spatial information in relation to long-term enhancement of hippocampal synapses. Behav Neurosci 99: 1040-1048, 1985.
    • (1985) Behav Neurosci , vol.99 , pp. 1040-1048
    • Barnes, C.A.1    McNaughton, B.L.2
  • 4
    • 0034282068 scopus 로고    scopus 로고
    • LTP induction threshold change in old rats at the perforant path - granule cell synapse
    • Barnes CA, Rao G, Houston FP. LTP induction threshold change in old rats at the perforant path - granule cell synapse. Neurobiol Aging 21: 613-620, 2000.
    • (2000) Neurobiol Aging , vol.21 , pp. 613-620
    • Barnes, C.A.1    Rao, G.2    Houston, F.P.3
  • 5
    • 0029976891 scopus 로고    scopus 로고
    • Functional integrity of NMDA-dependent LTP induction mechanisms across the lifespan of F-344 rats
    • Barnes CA, Rao G, McNaughton BL. Functional integrity of NMDA-dependent LTP induction mechanisms across the lifespan of F-344 rats. Learn Mem 3: 124-137, 1996.
    • (1996) Learn Mem , vol.3 , pp. 124-137
    • Barnes, C.A.1    Rao, G.2    McNaughton, B.L.3
  • 6
    • 0019199038 scopus 로고
    • The effects of repetitive low frequency stimulation on control and "potentiated" synaptic responses in the hippocampus
    • Barrionuevo G, Schottler F, Lynch G. The effects of repetitive low frequency stimulation on control and "potentiated" synaptic responses in the hippocampus. Life Sci 27: 2385-2391, 1980.
    • (1980) Life Sci , vol.27 , pp. 2385-2391
    • Barrionuevo, G.1    Schottler, F.2    Lynch, G.3
  • 7
    • 0027476024 scopus 로고
    • A synaptic model of memory: Long-term potentiation in the hippocampus
    • Bliss TV, Collingridge GL. A synaptic model of memory: long-term potentiation in the hippocampus. Nature 361: 31-39, 1993.
    • (1993) Nature , vol.361 , pp. 31-39
    • Bliss, T.V.1    Collingridge, G.L.2
  • 8
    • 0015799240 scopus 로고
    • Long-lasting potentiation of synaptic transmission in the dentate area of the anaesthetized rabbit following stimulation of the perforant path
    • Bliss TV, Lomo T. Long-lasting potentiation of synaptic transmission in the dentate area of the anaesthetized rabbit following stimulation of the perforant path. J Physiol 232: 331-356, 1973.
    • (1973) J Physiol , vol.232 , pp. 331-356
    • Bliss, T.V.1    Lomo, T.2
  • 9
    • 0030757446 scopus 로고    scopus 로고
    • Reversal of LTP in the hippocampal afferent fiber system to the prefrontal cortex in vivo with low-frequency patterns of stimulation that do not produce LTD
    • Burette F, Jay TM, Laroche S. Reversal of LTP in the hippocampal afferent fiber system to the prefrontal cortex in vivo with low-frequency patterns of stimulation that do not produce LTD. J Neurophysiol 78: 1155-1160, 1997.
    • (1997) J Neurophysiol , vol.78 , pp. 1155-1160
    • Burette, F.1    Jay, T.M.2    Laroche, S.3
  • 11
    • 0027193830 scopus 로고
    • Age-related alterations in potentiation in the CA1 region in F344 rats
    • Deupree DL, Bradley J, Turner DA. Age-related alterations in potentiation in the CA1 region in F344 rats. Neurobiol Aging 14: 249-258, 1993.
    • (1993) Neurobiol Aging , vol.14 , pp. 249-258
    • Deupree, D.L.1    Bradley, J.2    Turner, D.A.3
  • 12
    • 0027195617 scopus 로고
    • Bidirectional long-term modification of synaptic effectiveness in the adult and immature hippocampus
    • Dudek SM, Bear MF. Bidirectional long-term modification of synaptic effectiveness in the adult and immature hippocampus. J Neurosci 13: 2910-2918, 1993.
    • (1993) J Neurosci , vol.13 , pp. 2910-2918
    • Dudek, S.M.1    Bear, M.F.2
  • 13
    • 0028846935 scopus 로고
    • Stimulation at 1-5 Hz does not produce long-term depression or depotentiation in the hippocampus of the adult rat in vivo
    • Errington ML, Bliss TV, Richter-Levin G, Yenk K, Doyere V, Laroche S. Stimulation at 1-5 Hz does not produce long-term depression or depotentiation in the hippocampus of the adult rat in vivo. J Neurophysiol 74: 1793-1799, 1995.
    • (1995) J Neurophysiol , vol.74 , pp. 1793-1799
    • Errington, M.L.1    Bliss, T.V.2    Richter-Levin, G.3    Yenk, K.4    Doyere, V.5    Laroche, S.6
  • 14
    • 0032737984 scopus 로고    scopus 로고
    • Involvement of hippocampal synaptic plasticity in age-related memory decline
    • Foster TC. Involvement of hippocampal synaptic plasticity in age-related memory decline. Brain Res Rev 30: 236-249, 1999.
    • (1999) Brain Res Rev , vol.30 , pp. 236-249
    • Foster, T.C.1
  • 15
    • 33947596408 scopus 로고    scopus 로고
    • Susceptibility to induction of long-term depression is associated with impaired memory in aged Fischer 344 rats
    • Foster TC, Kumar A. Susceptibility to induction of long-term depression is associated with impaired memory in aged Fischer 344 rats. Neurobiol Learn Mem 87: 522-535, 2007.
    • (2007) Neurobiol Learn Mem , vol.87 , pp. 522-535
    • Foster, T.C.1    Kumar, A.2
  • 16
    • 0031451847 scopus 로고    scopus 로고
    • 2+-dependent processes: Relation to hippocampal synaptic plasticity
    • 2+-dependent processes: relation to hippocampal synaptic plasticity. Hippocampus 7: 602-612, 1997.
    • (1997) Hippocampus , vol.7 , pp. 602-612
    • Foster, T.C.1    Norris, C.M.2
  • 17
    • 0025779446 scopus 로고
    • Reversal of long-term potentiation (depotentiation) induced by tetanus stimulation of the input to CA1 neurons of guinea pig hippocampal slices
    • Fujii S, Saito K, Miyakawa H, Ito K, Kato H. Reversal of long-term potentiation (depotentiation) induced by tetanus stimulation of the input to CA1 neurons of guinea pig hippocampal slices. Brain Res 555: 112-122, 1991.
    • (1991) Brain Res , vol.555 , pp. 112-122
    • Fujii, S.1    Saito, K.2    Miyakawa, H.3    Ito, K.4    Kato, H.5
  • 18
    • 0028895747 scopus 로고
    • Hippocampal markers of age-related memory dysfunction: Behavioral, electrophysiological and morphological perspectives
    • Geinisman Y, Detoledo-Morrell L, Morrell F, Heller RE. Hippocampal markers of age-related memory dysfunction: behavioral, electrophysiological and morphological perspectives. Prog Neurobiol 45: 223-252, 1995.
    • (1995) Prog Neurobiol , vol.45 , pp. 223-252
    • Geinisman, Y.1    Detoledo-Morrell, L.2    Morrell, F.3    Heller, R.E.4
  • 19
    • 0025373621 scopus 로고
    • Testosterone fails to reverse spatial memory decline in aged rats and impairs retention in young and middle-aged animals
    • Goudsmit E, Van de Poll NE, Swaab DF. Testosterone fails to reverse spatial memory decline in aged rats and impairs retention in young and middle-aged animals. Behav Neural Biol 53: 6-20, 1990.
    • (1990) Behav Neural Biol , vol.53 , pp. 6-20
    • Goudsmit, E.1    Van de Poll, N.E.2    Swaab, D.F.3
  • 20
    • 0037165871 scopus 로고    scopus 로고
    • Age-related and laminar-specific dendritic changes in the medial frontal cortex of the rat
    • Grill JD, Riddle DR. Age-related and laminar-specific dendritic changes in the medial frontal cortex of the rat. Brain Res 937: 8-21, 2002.
    • (2002) Brain Res , vol.937 , pp. 8-21
    • Grill, J.D.1    Riddle, D.R.2
  • 21
    • 0031890179 scopus 로고    scopus 로고
    • Primed facilitation of homosynaptic long-term depression and depotentiation in rat hippocampus
    • Holland LL, Wagner JJ. Primed facilitation of homosynaptic long-term depression and depotentiation in rat hippocampus. J Neurosci 18: 887-894, 1998.
    • (1998) J Neurosci , vol.18 , pp. 887-894
    • Holland, L.L.1    Wagner, J.J.2
  • 22
    • 0036948518 scopus 로고    scopus 로고
    • Alterations in the balance of protein kinase and phosphatase activities and age-related impairments of synaptic transmission and long-term potentiation
    • Hsu KS, Huang CC, Liang YC, Wu HM, Chen YL, Lo SW, Ho WC. Alterations in the balance of protein kinase and phosphatase activities and age-related impairments of synaptic transmission and long-term potentiation. Hippocampus 12: 787-802, 2002.
    • (2002) Hippocampus , vol.12 , pp. 787-802
    • Hsu, K.S.1    Huang, C.C.2    Liang, Y.C.3    Wu, H.M.4    Chen, Y.L.5    Lo, S.W.6    Ho, W.C.7
  • 23
    • 0032484517 scopus 로고    scopus 로고
    • Increasing age reduces expression of long-term depression and dynamic range of transmission plasticity in CA1 field of the rat hippocampus
    • Kamal A, Biessels GJ, Gispen WH, Urban IJ. Increasing age reduces expression of long-term depression and dynamic range of transmission plasticity in CA1 field of the rat hippocampus. Neuroscience 83: 707-715, 1998.
    • (1998) Neuroscience , vol.83 , pp. 707-715
    • Kamal, A.1    Biessels, G.J.2    Gispen, W.H.3    Urban, I.J.4
  • 24
    • 0033978538 scopus 로고    scopus 로고
    • Different forms of LTD in the CA1 region of the hippocampus: Role of age and stimulus protocol
    • Kemp N, McQueen J, Faulkes S, Bashir ZI. Different forms of LTD in the CA1 region of the hippocampus: role of age and stimulus protocol. Eur J Neurosci 12: 360-366, 2000.
    • (2000) Eur J Neurosci , vol.12 , pp. 360-366
    • Kemp, N.1    McQueen, J.2    Faulkes, S.3    Bashir, Z.I.4
  • 26
    • 2442489729 scopus 로고    scopus 로고
    • Enhanced long-term potentiation during aging is masked by processes involving intracellular calcium stores
    • Kumar A, Foster TC. Enhanced long-term potentiation during aging is masked by processes involving intracellular calcium stores. J Neurophysiol 91: 2437-2444, 2004.
    • (2004) J Neurophysiol , vol.91 , pp. 2437-2444
    • Kumar, A.1    Foster, T.C.2
  • 27
    • 11144265809 scopus 로고    scopus 로고
    • Intracellular calcium stores contribute to increased susceptibility to LTD induction during aging
    • Kumar A, Foster TC. Intracellular calcium stores contribute to increased susceptibility to LTD induction during aging. Brain Res 1031: 125-128, 2005.
    • (2005) Brain Res , vol.1031 , pp. 125-128
    • Kumar, A.1    Foster, T.C.2
  • 28
    • 0018146937 scopus 로고
    • Impaired synaptic potentiation processes in the hippocampus of aged, memory-deficient rats
    • Landfield PW, McGaugh JL, Lynch G. Impaired synaptic potentiation processes in the hippocampus of aged, memory-deficient rats. Brain Res 150: 85-101, 1978.
    • (1978) Brain Res , vol.150 , pp. 85-101
    • Landfield, P.W.1    McGaugh, J.L.2    Lynch, G.3
  • 29
    • 0022461612 scopus 로고
    • Patterned stimulation at the theta frequency is optimal for the induction of hippocampal long-term potentiation
    • Larson J, Wong D, Lynch G. Patterned stimulation at the theta frequency is optimal for the induction of hippocampal long-term potentiation. Brain Res 368: 347-350, 1986.
    • (1986) Brain Res , vol.368 , pp. 347-350
    • Larson, J.1    Wong, D.2    Lynch, G.3
  • 30
    • 28044447423 scopus 로고    scopus 로고
    • NMDA receptor-independent long-term depression correlates with successful aging in rats
    • Lee HK, Min SS, Gallagher M, Kirkwood A. NMDA receptor-independent long-term depression correlates with successful aging in rats. Nat Neurosci 8: 1657-1659, 2005.
    • (2005) Nat Neurosci , vol.8 , pp. 1657-1659
    • Lee, H.K.1    Min, S.S.2    Gallagher, M.3    Kirkwood, A.4
  • 31
    • 0025320544 scopus 로고
    • Associative synaptic potentiation and depression: Quantification of dissociable modifications in the hippocampal dentate gyrus favors a particular class of synaptic modification equations
    • Lopez HS, Burger B, Dickstein R, Desmond NL, Levy WB. Associative synaptic potentiation and depression: quantification of dissociable modifications in the hippocampal dentate gyrus favors a particular class of synaptic modification equations. Synapse 5: 33-47, 1990.
    • (1990) Synapse , vol.5 , pp. 33-47
    • Lopez, H.S.1    Burger, B.2    Dickstein, R.3    Desmond, N.L.4    Levy, W.B.5
  • 33
    • 4043069258 scopus 로고    scopus 로고
    • Bi-directional plasticity and age-dependent long-term depression at mouse CA3-CA1 hippocampal synapses
    • Milner AJ, Cummings DM, Spencer JP, Murphy KP. Bi-directional plasticity and age-dependent long-term depression at mouse CA3-CA1 hippocampal synapses. Neurosci Lett 367: 1-5, 2004.
    • (2004) Neurosci Lett , vol.367 , pp. 1-5
    • Milner, A.J.1    Cummings, D.M.2    Spencer, J.P.3    Murphy, K.P.4
  • 34
    • 0034062504 scopus 로고    scopus 로고
    • Deficits in nitric oxide production after tetanic stimulation are related to the reduction of long-term potentiation in Schaffer-CA1 synapses in aged Fischer 344 rats
    • Mori K, Togashi H, Matsumoto M, Yoshioka M. Deficits in nitric oxide production after tetanic stimulation are related to the reduction of long-term potentiation in Schaffer-CA1 synapses in aged Fischer 344 rats. Acta Physiol Scand 169: 79-85, 2000.
    • (2000) Acta Physiol Scand , vol.169 , pp. 79-85
    • Mori, K.1    Togashi, H.2    Matsumoto, M.3    Yoshioka, M.4
  • 37
    • 0023235657 scopus 로고
    • Analysis of survival data on aging rat cohorts: Pitfalls and some practical considerations
    • Mos J, Hollander CF. Analysis of survival data on aging rat cohorts: pitfalls and some practical considerations. Mech Aging Dev 38: 89-105, 1987.
    • (1987) Mech Aging Dev , vol.38 , pp. 89-105
    • Mos, J.1    Hollander, C.F.2
  • 38
    • 0026458086 scopus 로고
    • Mechanisms underlying induction of homosynaptic long-term depression in area CA1 of the hippocampus
    • Mulkey RM, Malenka RC. Mechanisms underlying induction of homosynaptic long-term depression in area CA1 of the hippocampus. Neuron 9: 967-975, 1992.
    • (1992) Neuron , vol.9 , pp. 967-975
    • Mulkey, R.M.1    Malenka, R.C.2
  • 39
    • 0028969947 scopus 로고
    • Heterosynaptic interactions between LTP and LTD in CA1 hippocampal slices
    • Muller D, Hefft S, Figurov A. Heterosynaptic interactions between LTP and LTD in CA1 hippocampal slices. Neuron 14: 599-605, 1995.
    • (1995) Neuron , vol.14 , pp. 599-605
    • Muller, D.1    Hefft, S.2    Figurov, A.3
  • 40
    • 7944235804 scopus 로고    scopus 로고
    • Increased neuronal excitability, synaptic plasticity, and learning in aged Kvbeta1.1 knockout mice
    • Murphy GG, Fedorov NB, Giese KP, Ohno M, Friedman E, Chen R, Silva AJ. Increased neuronal excitability, synaptic plasticity, and learning in aged Kvbeta1.1 knockout mice. Curr Biol 14: 1907-1915, 2004.
    • (2004) Curr Biol , vol.14 , pp. 1907-1915
    • Murphy, G.G.1    Fedorov, N.B.2    Giese, K.P.3    Ohno, M.4    Friedman, E.5    Chen, R.6    Silva, A.J.7
  • 41
    • 0031732014 scopus 로고    scopus 로고
    • Alterations in the balance of protein kinase/phosphatase activities parallel reduced synaptic strength during aging
    • Norris CM, Halpain S, Foster TC. Alterations in the balance of protein kinase/phosphatase activities parallel reduced synaptic strength during aging. J Neurophysiol 80: 1567-1570, 1998.
    • (1998) J Neurophysiol , vol.80 , pp. 1567-1570
    • Norris, C.M.1    Halpain, S.2    Foster, T.C.3
  • 42
    • 0029795945 scopus 로고    scopus 로고
    • Increased susceptibility to induction of long-term depression and long- term potentiation reversal during aging
    • Norris CM, Korol DL, Foster TC. Increased susceptibility to induction of long-term depression and long- term potentiation reversal during aging. J Neurosci 16: 5382-5392, 1996.
    • (1996) J Neurosci , vol.16 , pp. 5382-5392
    • Norris, C.M.1    Korol, D.L.2    Foster, T.C.3
  • 43
    • 0028464990 scopus 로고
    • Low-frequency stimulation erases LTP through an NMDA receptor-mediated activation of protein phosphatases
    • O'Dell TJ, Kandel ER. Low-frequency stimulation erases LTP through an NMDA receptor-mediated activation of protein phosphatases. Learn Mem 1: 129-139, 1994.
    • (1994) Learn Mem , vol.1 , pp. 129-139
    • O'Dell, T.J.1    Kandel, E.R.2
  • 44
    • 0030995998 scopus 로고    scopus 로고
    • Two distinct forms of long-term depression coexist in CA1 hippocampal pyramidal cells
    • Oliet SH, Malenka RC, Nicoll RA. Two distinct forms of long-term depression coexist in CA1 hippocampal pyramidal cells. Neuron 18: 969-982, 1997.
    • (1997) Neuron , vol.18 , pp. 969-982
    • Oliet, S.H.1    Malenka, R.C.2    Nicoll, R.A.3
  • 45
    • 0037936789 scopus 로고    scopus 로고
    • Impact of aging on hippocampal function: Plasticity, network dynamics, and cognition
    • Rosenzweig ES, Barnes CA. Impact of aging on hippocampal function: plasticity, network dynamics, and cognition. Prog Neurobiol 69: 143-179, 2003.
    • (2003) Prog Neurobiol , vol.69 , pp. 143-179
    • Rosenzweig, E.S.1    Barnes, C.A.2
  • 46
    • 0030686555 scopus 로고    scopus 로고
    • Role of temporal summation in age-related long-term potentiation-induction deficits
    • Rosenzweig ES, Rao G, McNaughton BL, Barnes CA. Role of temporal summation in age-related long-term potentiation-induction deficits. Hippocampus 7: 549-558, 1997.
    • (1997) Hippocampus , vol.7 , pp. 549-558
    • Rosenzweig, E.S.1    Rao, G.2    McNaughton, B.L.3    Barnes, C.A.4
  • 47
    • 0031893277 scopus 로고    scopus 로고
    • Aging differentially alters forms of long-term potentiation in rat hippocampal area CA1
    • Shankar S, Teyler TJ, Robbins N. Aging differentially alters forms of long-term potentiation in rat hippocampal area CA1. J Neurophysiol 79: 334-341, 1998.
    • (1998) J Neurophysiol , vol.79 , pp. 334-341
    • Shankar, S.1    Teyler, T.J.2    Robbins, N.3
  • 48
    • 0032873827 scopus 로고    scopus 로고
    • Hippocampus as a memory map: Synaptic plasticity and memory encoding by hippocampal neurons
    • Shapiro ML, Eichenbaum H. Hippocampus as a memory map: synaptic plasticity and memory encoding by hippocampal neurons. Hippocampus 9: 365-384, 1999.
    • (1999) Hippocampus , vol.9 , pp. 365-384
    • Shapiro, M.L.1    Eichenbaum, H.2
  • 49
    • 0029989471 scopus 로고    scopus 로고
    • LTD, LTP, and the sliding threshold for long-term synaptic plasticity
    • Stanton PK. LTD, LTP, and the sliding threshold for long-term synaptic plasticity. Hippocampus 6: 35-42, 1996.
    • (1996) Hippocampus , vol.6 , pp. 35-42
    • Stanton, P.K.1
  • 50
    • 0028102787 scopus 로고
    • Excitatory stimulation during postsynaptic inhibition induces long-term depression in hippocampus in vivo
    • Thiels E, Barrionuevo G, Berger TW. Excitatory stimulation during postsynaptic inhibition induces long-term depression in hippocampus in vivo. J Neurophysiol 72: 3009-3016, 1994.
    • (1994) J Neurophysiol , vol.72 , pp. 3009-3016
    • Thiels, E.1    Barrionuevo, G.2    Berger, T.W.3
  • 51
    • 0037448150 scopus 로고    scopus 로고
    • Chronic ethanol treatment reduces the magnitude of hippocampal LTD in the adult rat
    • Thinschmidt JS, Walker DW, King MA. Chronic ethanol treatment reduces the magnitude of hippocampal LTD in the adult rat. Synapse 48: 189-197, 2003.
    • (2003) Synapse , vol.48 , pp. 189-197
    • Thinschmidt, J.S.1    Walker, D.W.2    King, M.A.3
  • 52
    • 0037112195 scopus 로고    scopus 로고
    • Theta-frequency synaptic potentiation in CA1 in vitro distinguishes cognitively impaired from unimpaired aged Fischer 344 rats
    • Tombaugh GC, Rowe WB, Chow AR, Michael TH, Rose GM. Theta-frequency synaptic potentiation in CA1 in vitro distinguishes cognitively impaired from unimpaired aged Fischer 344 rats. J Neurosci 22: 9932-9940, 2002.
    • (2002) J Neurosci , vol.22 , pp. 9932-9940
    • Tombaugh, G.C.1    Rowe, W.B.2    Chow, A.R.3    Michael, T.H.4    Rose, G.M.5
  • 53
    • 0027164007 scopus 로고
    • Decreased number of vasopressin immunoreactive neurons in the medial amygdala and locus coeruleus of the aged rat
    • Van Zwieten EJ, Kos WT, Ravid R, Swaab DF. Decreased number of vasopressin immunoreactive neurons in the medial amygdala and locus coeruleus of the aged rat. Neurobiol Aging 14: 245-248, 1993.
    • (1993) Neurobiol Aging , vol.14 , pp. 245-248
    • Van Zwieten, E.J.1    Kos, W.T.2    Ravid, R.3    Swaab, D.F.4
  • 54
    • 0027360012 scopus 로고
    • Age dependence of homosynaptic non-NMDA mediated long-term depression in field CA1 of rat hippocampal slices
    • Velisek L, Moshe SL, Stanton PK. Age dependence of homosynaptic non-NMDA mediated long-term depression in field CA1 of rat hippocampal slices. Brain Res Dev Brain Res 75: 253-260, 1993.
    • (1993) Brain Res Dev Brain Res , vol.75 , pp. 253-260
    • Velisek, L.1    Moshe, S.L.2    Stanton, P.K.3
  • 55
    • 0034352088 scopus 로고    scopus 로고
    • 17beta-estradiol suppresses expression of long-term depression in aged rats
    • Vouimba RM, Foy MR, Foy JG, Thompson RF. 17beta-estradiol suppresses expression of long-term depression in aged rats. Brain Res Bull 53: 783-787, 2000.
    • (2000) Brain Res Bull , vol.53 , pp. 783-787
    • Vouimba, R.M.1    Foy, M.R.2    Foy, J.G.3    Thompson, R.F.4
  • 56
    • 0028954506 scopus 로고
    • GABAergic and developmental influences on homosynaptic LTD and depotentiation in rat hippocampus
    • Wagner JJ, Alger BE. GABAergic and developmental influences on homosynaptic LTD and depotentiation in rat hippocampus. J Neurosci 15: 1577-1586, 1995.
    • (1995) J Neurosci , vol.15 , pp. 1577-1586
    • Wagner, J.J.1    Alger, B.E.2
  • 57
    • 0029989470 scopus 로고    scopus 로고
    • Homosynaptic LTD and depotentiation: Do they differ in name only?
    • Wagner JJ, Alger BE. Homosynaptic LTD and depotentiation: do they differ in name only? Hippocampus 6: 24-29, 1996.
    • (1996) Hippocampus , vol.6 , pp. 24-29
    • Wagner, J.J.1    Alger, B.E.2
  • 58
    • 0036522980 scopus 로고    scopus 로고
    • Long-term depression in the developing hippocampus: Low induction threshold and synapse nonspecificity
    • Wasling P, Hanse E, Gustafsson B. Long-term depression in the developing hippocampus: low induction threshold and synapse nonspecificity. J Neurosci 22: 1823-1830, 2002.
    • (2002) J Neurosci , vol.22 , pp. 1823-1830
    • Wasling, P.1    Hanse, E.2    Gustafsson, B.3
  • 59
    • 0037333634 scopus 로고    scopus 로고
    • Age-related changes in theta frequency stimulation-induced long-term potentiation
    • Watabe AM, O'Dell TJ. Age-related changes in theta frequency stimulation-induced long-term potentiation. Neurobiol Aging 24: 267-272, 2003.
    • (2003) Neurobiol Aging , vol.24 , pp. 267-272
    • Watabe, A.M.1    O'Dell, T.J.2
  • 60
    • 0027221606 scopus 로고
    • Priming of homosynaptic long-term depression in hippocampus by previous synaptic activity
    • Wexler EM, Stanton PK. Priming of homosynaptic long-term depression in hippocampus by previous synaptic activity. Neuroreport 4: 591-594, 1993.
    • (1993) Neuroreport , vol.4 , pp. 591-594
    • Wexler, E.M.1    Stanton, P.K.2
  • 61
    • 1342290210 scopus 로고    scopus 로고
    • The effects of rAAV2-mediated NGF gene delivery in adult and aged rats
    • Wu K, Meyers CA, Guerra NK, King MA, Meyer EM. The effects of rAAV2-mediated NGF gene delivery in adult and aged rats. Mol Ther 9: 262-269, 2004.
    • (2004) Mol Ther , vol.9 , pp. 262-269
    • Wu, K.1    Meyers, C.A.2    Guerra, N.K.3    King, M.A.4    Meyer, E.M.5
  • 62
    • 3042546220 scopus 로고    scopus 로고
    • Reversal and consolidation of activity-induced synaptic modifications
    • Zhou Q, Poo MM. Reversal and consolidation of activity-induced synaptic modifications. Trends Neurosci 27: 378-383, 2004.
    • (2004) Trends Neurosci , vol.27 , pp. 378-383
    • Zhou, Q.1    Poo, M.M.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.