-
1
-
-
0020700160
-
Serologic aspects of IgG4 antibodies. I. Prolonged immunization results in an IgG4-restricted response
-
Aalberse RC, van der Gaag R, van Leeuwen J (1983) Serologic aspects of IgG4 antibodies. I. Prolonged immunization results in an IgG4-restricted response. J Immunol 130(2):722-726 (Pubitemid 13186294)
-
(1983)
Journal of Immunology
, vol.130
, Issue.2
, pp. 722-726
-
-
Aalberse, R.C.1
Van Der Gaag, R.2
Van Leeuwen, J.3
-
2
-
-
39549088649
-
Neonatal FcR expression in bone marrow-derived cells functions to protect serum IgG from catabolism
-
Akilesh S, Christianson GJ, Roopenian DC, Shaw AS (2007) Neonatal FcR expression in bone marrow-derived cells functions to protect serum IgG from catabolism. J Immunol 179(7): 4580-4588
-
(2007)
J Immunol
, vol.179
, Issue.7
, pp. 4580-4588
-
-
Akilesh, S.1
Christianson, G.J.2
Roopenian, D.C.3
Shaw, A.S.4
-
3
-
-
34547101712
-
Modifications to an Fcγ-Fcε fusion protein alterits effectiveness in the inhibition of FcεRI-mediated functions
-
DOI 10.1016/j.jaci.2007.04.019, PII S0091674907008093
-
Allen LC, Kepley CL, Saxon A, Zhang K (2007) Modifications to an Fcgamma-Fcvarepsilon fusion protein alter its effectiveness in the inhibition of FcvarepsilonRI-mediated functions. J Allergy Clin Immunol 120(2):462-468 (Pubitemid 47102381)
-
(2007)
Journal of Allergy and Clinical Immunology
, vol.120
, Issue.2
, pp. 462-468
-
-
Allen, L.C.1
Kepley, C.L.2
Saxon, A.3
Zhang, K.4
-
4
-
-
0018756849
-
Immunoregulatory function of specific IgG. II. Clinical evaluations of combined active and passive immunotherapy
-
Bernstein IL, Michael JG, Malkiel S, Sweet LC, Brackett RG (1979) Immunoregulatory function of specific IgG. II. Clinical evaluation of combined active and passive immunotherapy. Int Arch Allergy Appl Immunol 58(1):30-37 (Pubitemid 9105184)
-
(1979)
International Archives of Allergy and Applied Immunology
, vol.58
, Issue.1
, pp. 30-37
-
-
Bernstein, I.L.1
Michael, J.G.2
Malkiel, S.3
-
5
-
-
0025179309
-
Evaluation of immunotherapy-induced changes in specific IgE, IgG and IgG subclasses in birch pollen allergic patients by means of immunoblotting. Correlation with clinical response
-
Birkner T, Rumpold H, Jarolim E, Ebner H, Breitenbach M, Skvaril F, Scheiner O, Kraft D (1990) Evaluation of immunotherapy-induced changes in specific IgE, IgG and IgG subclasses in birch pollen allergic patients by means of immunoblotting. Correlation with clinical response. Allergy 45(6):418-426 (Pubitemid 20286256)
-
(1990)
Allergy: European Journal of Allergy and Clinical Immunology
, vol.45
, Issue.6
, pp. 418-426
-
-
Birkner, T.1
Rumpold, H.2
Jarolim, E.3
Ebner, H.4
Breitenbach, M.5
Skvaril, F.6
Scheiner, O.7
Kraft, D.8
-
6
-
-
18244403172
-
Is immunotherapy-induced birch-pollen-specific IgG4 a marker for decreased allergen-specific sensitivity?
-
DOI 10.1159/000084227
-
Bodtger U, Ejrnaes AM, Hummelshoj L, Jacobi HH, Poulsen LK, Svenson M (2005) Is immunotherapy-induced birch-pollen-specific IgG4 a marker for decreased allergen-specific sensitivity? Int Arch Allergy Immunol 136(4):340-346 (Pubitemid 41094497)
-
(2005)
International Archives of Allergy and Immunology
, vol.136
, Issue.4
, pp. 340-346
-
-
Bodtger, U.1
Ejrnaes, A.M.2
Hummelshoj, L.3
Jacobi, H.H.4
Poulsen, L.K.5
Svenson, M.6
-
7
-
-
0023193540
-
Combination of passive and active immunization in honeybee venom immunotherapy
-
DOI 10.1016/0091-6749(87)90245-4
-
Bousquet J, Fontez A, Aznar R, Robinet-Levy M, Michel FB (1987) Combination of passive and active immunization in honeybee venom immunotherapy. J Allergy Clin Immunol 79(6):947-954 (Pubitemid 17085589)
-
(1987)
Journal of Allergy and Clinical Immunology
, vol.79
, Issue.6
, pp. 947-954
-
-
Bousquet, J.1
Fontez, A.2
Aznar, R.3
-
8
-
-
77950956393
-
IgG antibodies produced during subcutaneous allergen immunotherapy mediate inhibition of basophil activation via a mechanism involving both FcgammaRIIA and FcgammaRIIB
-
Cady CT, Powell MS, Harbeck RJ, Giclas PC, Murphy JR, Katial RK, Weber RW, Hogarth PM, Johnson S, Bonvini E, Koenig S, Cambier JC (2010) IgG antibodies produced during subcutaneous allergen immunotherapy mediate inhibition of basophil activation via a mechanism involving both FcgammaRIIA and FcgammaRIIB. Immunol Lett 130(1-2):57-65
-
(2010)
Immunol Lett
, vol.130
, Issue.1-2
, pp. 57-65
-
-
Cady, C.T.1
Powell, M.S.2
Harbeck, R.J.3
Giclas, P.C.4
Murphy, J.R.5
Katial, R.K.6
Weber, R.W.7
Hogarth, P.M.8
Johnson, S.9
Bonvini, E.10
Koenig, S.11
Cambier, J.C.12
-
9
-
-
0032868653
-
Therapeutic antibody fragments with prolonged in vivo half-lives
-
DOI 10.1038/11717
-
Chapman AP, Antoniw P, Spitali M, West S, Stephens S, King DJ (1999) Therapeutic antibody fragments with prolonged in vivo half-lives. Nat Biotechnol 17(8):780-783 (Pubitemid 29365106)
-
(1999)
Nature Biotechnology
, vol.17
, Issue.8
, pp. 780-783
-
-
Chapman, A.P.1
Antoniw, P.2
Spitali, M.3
West, S.4
Stephens, S.5
King, D.J.6
-
10
-
-
58149083084
-
Modifying antibody specificity by chain shuffling of V/V between antibodies with related specificities
-
Christensen PA, Danielczyk A, Ravn P, Larsen M, Stahn R, Karsten U, Goletz S (2009) Modifying antibody specificity by chain shuffling of V/V between antibodies with related specificities. Scand J Immunol 69(1):1-10
-
(2009)
Scand J Immunol
, vol.69
, Issue.1
, pp. 1-10
-
-
Christensen, P.A.1
Danielczyk, A.2
Ravn, P.3
Larsen, M.4
Stahn, R.5
Karsten, U.6
Goletz, S.7
-
11
-
-
77952240186
-
Modulating the pharmacokinetics of therapeutic antibodies
-
Constantinou A, Chen C, Deonarain MP (2010) Modulating the pharmacokinetics of therapeutic antibodies. Biotechnol Lett 32(5):609-622
-
(2010)
Biotechnol Lett
, vol.32
, Issue.5
, pp. 609-622
-
-
Constantinou, A.1
Chen, C.2
Deonarain, M.P.3
-
12
-
-
34247569209
-
Serological evidence of immunity with coexisting sensitization in hay fever type of humanallergy
-
Cooke R (1935) Serological evidence of immunity with coexisting sensitization in hay fever type of humanallergy. J Exp Med 62:733-750
-
(1935)
J Exp Med
, vol.62
, pp. 733-750
-
-
Cooke, R.1
-
13
-
-
77953039047
-
A randomized, controlled, phase 2 study of AMG 317, an IL-4Ralpha antagonist, in patients with asthma
-
Corren J, Busse W, Meltzer EO, Mansfield L, Bensch G, Fahrenholz J, Wenzel SE, Chon Y, Dunn M, Weng HH, Lin SL (2010) A randomized, controlled, phase 2 study of AMG 317, an IL-4Ralpha antagonist, in patients with asthma. Am J Respir Crit Care Med 181(8):788-796
-
(2010)
Am J Respir Crit Care Med
, vol.181
, Issue.8
, pp. 788-796
-
-
Corren, J.1
Busse, W.2
Meltzer, E.O.3
Mansfield, L.4
Bensch, G.5
Fahrenholz, J.6
Wenzel, S.E.7
Chon, Y.8
Dunn, M.9
Weng, H.H.10
Lin, S.L.11
-
14
-
-
33749436870
-
Immunotherapy with a ragweed-toll-like receptor 9 agonist vaccine for allergic rhinitis
-
DOI 10.1056/NEJMoa052916
-
Creticos PS, Schroeder JT, Hamilton RG, Balcer-Whaley SL, Khattignavong AP, Lindblad R, Li H, Coffman R, Seyfert V, Eiden JJ, Broide D (2006) Immunotherapy with a ragweed-toll-like receptor 9 agonist vaccine for allergic rhinitis. N Engl J Med 355(14):1445-1455 (Pubitemid 44511559)
-
(2006)
New England Journal of Medicine
, vol.355
, Issue.14
, pp. 1445-1455
-
-
Creticos, P.S.1
Schroeder, J.T.2
Hamilton, R.G.3
Balcer-Whaley, S.L.4
Khattignavong, A.P.5
Lindblad, R.6
Li, H.7
Coffman, R.8
Seyfert, V.9
Eiden, J.J.10
Broide, D.11
-
15
-
-
0343415612
-
Molecular characterization of human IgG monoclonal antibodies specific for the major birch pollen allergen Bet v 1. Anti-allergen IgG can enhance the anaphylactic reaction
-
DOI 10.1016/S0014-5793(99)01703-2, PII S0014579399017032
-
Denepoux S, Eibensteiner PB, Steinberger P, Vrtala S, Visco V, Weyer A, Kraft D, Banchereau J, Valenta R, Lebecque S (2000) Molecular characterization of human IgG monoclonal antibodies specific for the major birch pollen allergen Bet v 1. Anti-allergen IgG can enhance the anaphylactic reaction. FEBS Lett 465(1):39-46 (Pubitemid 30012112)
-
(2000)
FEBS Letters
, vol.465
, Issue.1
, pp. 39-46
-
-
Denepoux, S.1
Eibensteiner, P.B.2
Steinberger, P.3
Vrtala, S.4
Visco, V.5
Weyer, A.6
Kraft, D.7
Banchereau, J.8
Valenta, R.9
Lebecque, S.10
-
16
-
-
85004905442
-
High IgG4 antibody level is associated with failure of immunotherapy with inhalant allergens
-
Djurup R, Malling HJ (1987) High IgG4 antibody level is associated with failure of immunotherapy with inhalant allergens. Clin Allergy 17(5):459-468
-
(1987)
Clin Allergy
, vol.17
, Issue.5
, pp. 459-468
-
-
Djurup, R.1
Malling, H.J.2
-
17
-
-
2942623847
-
The blocking activity of birch pollen-specific immunotherapy-induced IgG4 is not qualitatively superior to that of other IgG subclasses
-
DOI 10.1016/j.molimm.2004.04.018, PII S0161589004001336
-
Ejrnaes AM, Bodtger U, Larsen JN, Svenson M (2004) The blocking activity of birch pollen-specific immunotherapy-induced IgG4 is not qualitatively superior to that of other IgG subclasses. Mol Immunol 41(5):471-478 (Pubitemid 38746657)
-
(2004)
Molecular Immunology
, vol.41
, Issue.5
, pp. 471-478
-
-
Ejrnaes, A.M.1
Bodtger, U.2
Larsen, J.N.3
Svenson, M.4
-
18
-
-
33644781575
-
Inhibition of rBet v 1-induced basophil histamine release with specific immunotherapy -induced serum immunoglobulin G: No evidence that FcγRIIB signalling is important
-
DOI 10.1111/j.1365-2222.2006.02442.x
-
Ejrnaes AM, Svenson M, Lund G, Larsen JN, Jacobi H (2006) Inhibition of rBet v 1-induced basophil histamine release with specific immunotherapy-induced serum immunoglobulin G: no evidence that FcgammaRIIB signalling is important. Clin Exp Allergy 36(3):273-282 (Pubitemid 43344708)
-
(2006)
Clinical and Experimental Allergy
, vol.36
, Issue.3
, pp. 273-282
-
-
Ejrnaes, A.M.1
Svenson, M.2
Lund, G.3
Larsen, J.N.4
Jacobi, H.5
-
19
-
-
64649099284
-
Affinity maturation of a humanized rat antibody for anti-RAGE therapy: Comprehensive mutagenesis reveals a high level of mutational plasticity both inside and outside the complementarity-determining regions
-
Finlay WJ, Cunningham O, Lambert MA, Darmanin-Sheehan A, Liu X, Fennell BJ, Mahon CM, Cummins E, Wade JM, O'Sullivan CM, Tan XY, Piche N, Pittman DD, Paulsen J, Tchistiakova L, Kodangattil S, Gill D, Hufton SE (2009) Affinity maturation of a humanized rat antibody for anti-RAGE therapy: comprehensive mutagenesis reveals a high level of mutational plasticity both inside and outside the complementarity-determining regions. J Mol Biol 388(3):541-558
-
(2009)
J Mol Biol
, vol.388
, Issue.3
, pp. 541-558
-
-
Finlay, W.J.1
Cunningham, O.2
Lambert, M.A.3
Darmanin-Sheehan, A.4
Liu, X.5
Fennell, B.J.6
Mahon, C.M.7
Cummins, E.8
Wade, J.M.9
O'Sullivan, C.M.10
Tan, X.Y.11
Piche, N.12
Pittman, D.D.13
Paulsen, J.14
Tchistiakova, L.15
Kodangattil, S.16
Gill, D.17
Hufton, S.E.18
-
20
-
-
0141958643
-
Renaissance of the blocking antibody concept in type I allergy
-
DOI 10.1159/000073260
-
Flicker S, Valenta R (2003) Renaissance of the blocking antibody concept in type I allergy. Int Arch Allergy Immunol 132(1):13-24 (Pubitemid 37256012)
-
(2003)
International Archives of Allergy and Immunology
, vol.132
, Issue.1
, pp. 13-24
-
-
Flicker, S.1
Valenta, R.2
-
21
-
-
0034292355
-
A human monoclonal IgE antibody defines a highly allergenic fragment of the major timothy grass pollen allergen, Phl p 5: Molecular, immunological, and structural characterization of the epitope-containing domain
-
Flicker S, Vrtala S, Steinberger P, Vangelista L, Bufe A, Petersen A, Ghannadan M, Sperr WR, Valent P, Norderhaug L, Bohle B, Stockinger H, Suphioglu C, Ong EK, Kraft D, Valenta R (2000) A human monoclonal IgE antibody defines a highly allergenic fragment of the major timothy grass pollen allergen, Phl p 5: molecular, immunological, and structural characterization of the epitope-containing domain. J Immunol 165(7):3849-3859 (Pubitemid 32057292)
-
(2000)
Journal of Immunology
, vol.165
, Issue.7
, pp. 3849-3859
-
-
Flicker, S.1
Vrtala, S.2
Steinberger, P.3
Vangelista, L.4
Bufe, A.5
Petersen, A.6
Ghannadan, M.7
Sperr, W.R.8
Valent, P.9
Norderhaug, L.10
Bohle, B.11
Stockinger, H.12
Suphioglu, C.13
Eng Kok Ong14
Kraft, D.15
Valenta, R.16
-
22
-
-
0036687715
-
1 antibody
-
DOI 10.1002/1521-4141(200208)32:8<2156::AID-IMMU2156>3.0.CO;2-A
-
Flicker S, Steinberger P, Norderhaug L, Sperr WR, Majlesi Y, Valent P, Kraft D, Valenta R (2002) Conversion of grass pollen allergen-specific human IgE into a protective IgG(1) antibody. Eur J Immunol 32(8):2156-2162 (Pubitemid 34965878)
-
(2002)
European Journal of Immunology
, vol.32
, Issue.8
, pp. 2156-2162
-
-
Flicker, S.1
Steinberger, P.2
Norderhaug, L.3
Sperr, W.R.4
Majlesi, Y.5
Valent, P.6
Kraft, D.7
Valenta, R.8
-
23
-
-
33646941045
-
Spatial clustering of the IgE epitopes on the major timothy grass pollen allergen Phl p 1: Importance for allergenic activity
-
DOI 10.1016/j.jaci.2006.02.012, PII S0091674906003241
-
Flicker S, Steinberger P, Ball T, Krauth MT, Verdino P, Valent P, Almo S, Valenta R (2006) Spatial clustering of the IgE epitopes on the major timothy grass pollen allergen Phl p 1: importance for allergenic activity. J Allergy Clin Immunol 117(6):1336-1343 (Pubitemid 43795725)
-
(2006)
Journal of Allergy and Clinical Immunology
, vol.117
, Issue.6
, pp. 1336-1343
-
-
Flicker, S.1
Steinberger, P.2
Ball, T.3
Krauth, M.-T.4
Verdino, P.5
Valent, P.6
Almo, S.7
Valenta, R.8
-
24
-
-
38349099945
-
Molecular characterization of a human immunoglobulin G4 antibody specific for the major birch pollen allergen, Bet v 1
-
Flicker S, Steinberger P, Eibensteiner PB, Lebecque S, Kraft D, Valenta R (2008) Molecular characterization of a human immunoglobulin G4 antibody specific for the major birch pollen allergen, Bet v 1. Clin Exp Allergy 38 (2):365-373
-
(2008)
Clin Exp Allergy
, vol.38
, Issue.2
, pp. 365-373
-
-
Flicker, S.1
Steinberger, P.2
Eibensteiner, P.B.3
Lebecque, S.4
Kraft, D.5
Valenta, R.6
-
25
-
-
71149100473
-
Placental transfer of allergen-specific IgG but not IgE from a specific immunotherapy-treated mother
-
e1
-
Flicker S, Marth K, Kofler H, Valenta R (2009) Placental transfer of allergen-specific IgG but not IgE from a specific immunotherapy-treated mother. J Allergy Clin Immunol 124(6):1358-1360 e1
-
(2009)
J Allergy Clin Immunol
, vol.124
, Issue.6
, pp. 1358-1360
-
-
Flicker, S.1
Marth, K.2
Kofler, H.3
Valenta, R.4
-
26
-
-
68349114852
-
Analysis of the antibody responses induced by subcutaneous injection immunother-apy with birch and Fagales pollen extracts adsorbed onto aluminum hydroxide
-
Gadermaier E, Flicker S, Aberer W, Egger C, Reider N, Focke M, Vrtala S, Kundi M, Valenta R (2010a) Analysis of the antibody responses induced by subcutaneous injection immunother-apy with birch and Fagales pollen extracts adsorbed onto aluminum hydroxide. Int Arch Allergy Immunol 151(1):17-27
-
(2010)
Int Arch Allergy Immunol
, vol.151
, Issue.1
, pp. 17-27
-
-
Gadermaier, E.1
Flicker, S.2
Aberer, W.3
Egger, C.4
Reider, N.5
Focke, M.6
Vrtala, S.7
Kundi, M.8
Valenta, R.9
-
27
-
-
80053498822
-
Evidence that the heavy-chain determines the specificity of IgE antibodies in allergy
-
Kansai, Japan, International Immunology Meeting Abstracts (2010) doi:10.1093/intimm/dxq108
-
Gadermaier E, Flicker S, Steinberger P, Valenta R (2010b) Evidence that the heavy-chain determines the specificity of IgE antibodies in allergy. 14th international congress of immunology, Kansai, Japan, International Immunology Meeting Abstracts (2010) 22 (Suppl 1 Pt 1): i138-i141. doi:10.1093/intimm/dxq108
-
(2010)
14th International Congress of Immunology
, vol.22
, Issue.SUPPL. 1 PART 1
-
-
Gadermaier, E.1
Flicker, S.2
Steinberger, P.3
Valenta, R.4
-
28
-
-
79961126849
-
Recombinant allergen-based monitoring of antibody responses during injection grass pollen immunotherapy and after 5 years of discontinuation
-
doi:10.1111/j.1398-9995.2011.02592.x
-
Gadermaier E, Staikuniene J, Scheiblhofer S, Thalhamer J, Kundi M, Westritschnig K, Swoboda I, Flicker S, Valenta R (2011) Recombinant allergen-based monitoring of antibody responses during injection grass pollen immunotherapy and after 5 years of discontinuation. Allergy doi:10.1111/j.1398- 9995.2011.02592.x
-
(2011)
Allergy
-
-
Gadermaier, E.1
Staikuniene, J.2
Scheiblhofer, S.3
Thalhamer, J.4
Kundi, M.5
Westritschnig, K.6
Swoboda, I.7
Flicker, S.8
Valenta, R.9
-
29
-
-
0036201914
-
Transcytosis and catabolism of antibody
-
Ghetie V, Ward ES (2002) Transcytosis and catabolism of antibody. Immunol Res 25(2):97-113 (Pubitemid 34264097)
-
(2002)
Immunologic Research
, vol.25
, Issue.2
, pp. 97-113
-
-
Ghetie, V.1
Ward, E.S.2
-
30
-
-
0029927482
-
Abnormally short serum half-lives of IgG in β2-microglobulin- deficient mice
-
DOI 10.1002/eji.1830260327
-
Ghetie V, Hubbard JG, Kim JK, Tsen MF, Lee Y, Ward ES (1996) Abnormally short serum half-lives of IgG in beta 2-microglobulin-deficient mice. Eur J Immunol 26(3):690-696 (Pubitemid 26091401)
-
(1996)
European Journal of Immunology
, vol.26
, Issue.3
, pp. 690-696
-
-
Ghetie, V.1
Hubbard, J.G.2
Kim, J.-K.3
Tsen, M.-F.4
Lee, Y.5
Ward, E.S.6
-
31
-
-
79955549894
-
Mapping of conformational IgE epitopes with peptide-specific monoclonal antibodies reveals simultaneous binding of different IgE antibodies to a surface patch on the major birch pollen allergen, Bet v 1
-
Gieras A, Cejka P, Blatt K, Focke-Tejkl M, Linhart B, Flicker S, Stoecklinger A, Marth K, Drescher A, Thalhamer J, Valent P, Majdic O, Valenta R (2011) Mapping of conformational IgE epitopes with peptide-specific monoclonal antibodies reveals simultaneous binding of different IgE antibodies to a surface patch on the major birch pollen allergen, Bet v 1. J Immunol 186(9):5333-5344
-
(2011)
J Immunol
, vol.186
, Issue.9
, pp. 5333-5344
-
-
Gieras, A.1
Cejka, P.2
Blatt, K.3
Focke-Tejkl, M.4
Linhart, B.5
Flicker, S.6
Stoecklinger, A.7
Marth, K.8
Drescher, A.9
Thalhamer, J.10
Valent, P.11
Majdic, O.12
Valenta, R.13
-
32
-
-
0027082901
-
Antibody engineering by codon-based mutagenesis in a filamentous phage vector system
-
Glaser SM, Yelton DE, Huse WD (1992) Antibody engineering by codon-based mutagenesis in a filamentous phage vector system. J Immunol 149(12):3903-3913 (Pubitemid 23068871)
-
(1992)
Journal of Immunology
, vol.149
, Issue.12
, pp. 3903-3913
-
-
Glaser, S.M.1
Yelton, D.E.2
Huse, W.D.3
-
33
-
-
0025740045
-
Effect of maternal immunotherapy on immediate skin test reactivity, specific rye i IgG and IgE antibody, and total IgE of the children
-
Glovsky MM, Ghekiere L, Rejzek E (1991) Effect of maternal immunotherapy on immediate skin test reactivity, specific rye I IgG and IgE antibody, and total IgE of the children. Ann Allergy 67(1):21-24
-
(1991)
Ann Allergy
, vol.67
, Issue.1
, pp. 21-24
-
-
Glovsky, M.M.1
Ghekiere, L.2
Rejzek, E.3
-
34
-
-
77950517325
-
The safety and side effects of monoclonal antibodies
-
Hansel TT, Kropshofer H, Singer T, Mitchell JA, George AJ (2010) The safety and side effects of monoclonal antibodies. Nat Rev Drug Discov 9(4):325-338
-
(2010)
Nat Rev Drug Discov
, vol.9
, Issue.4
, pp. 325-338
-
-
Hansel, T.T.1
Kropshofer, H.2
Singer, T.3
Mitchell, J.A.4
George, A.J.5
-
35
-
-
0016441705
-
Maximal rise in IgE antibody following ragweed pollination season
-
Henderson LL, Larson JB, Gleich GJ (1975) Maximal rise in IgE antibody following ragweed pollination season. J Allergy Clin Immunol 55(1):10-15
-
(1975)
J Allergy Clin Immunol
, vol.55
, Issue.1
, pp. 10-15
-
-
Henderson, L.L.1
Larson, J.B.2
Gleich, G.J.3
-
36
-
-
70449106421
-
Effects of omalizumab on markers of inflammation in patients with allergic asthma
-
Holgate S, Smith N, Massanari M, Jimenez P (2009) Effects of omalizumab on markers of inflammation in patients with allergic asthma. Allergy 64(12):1728-1736
-
(2009)
Allergy
, vol.64
, Issue.12
, pp. 1728-1736
-
-
Holgate, S.1
Smith, N.2
Massanari, M.3
Jimenez, P.4
-
37
-
-
0024833055
-
Generation of a large combinatorial library of the immunoglobulin repertoire in phage lambda
-
Huse WD, Sastry L, Iverson SA, Kang AS, Alting-Mees M, Burton DR, Benkovic SJ, Lerner RA (1989) Generation of a large combinatorial library of the immunoglobulin repertoire in phage lambda. Science 246(4935):1275-1281 (Pubitemid 20066710)
-
(1989)
Science
, vol.246
, Issue.4935
, pp. 1275-1281
-
-
Huse, W.D.1
Sastry, L.2
Iverson, S.A.3
Kang, A.S.4
Alting-Mees, M.5
Burton, D.R.6
Benkovic, S.J.7
Lerner, R.A.8
-
38
-
-
4043152040
-
Isolation of high-affinity human IgE and IgG antibodies recognising Bet v 1 and Humicola lanuginosa lipase from combinatorial phage libraries
-
DOI 10.1016/j.molimm.2004.05.009, PII S0161589004001993
-
Jakobsen CG, Bodtger U, Kristensen P, Poulsen LK, Roggen EL (2004) Isolation of high-affinity human IgE and IgG antibodies recognising Bet v 1 and Humicola lanuginosa lipase from combinatorial phage libraries. Mol Immunol 41(10):941-953 (Pubitemid 39070323)
-
(2004)
Molecular Immunology
, vol.41
, Issue.10
, pp. 941-953
-
-
Jakobsen, C.G.1
Bodtger, U.2
Kristensen, P.3
Poulsen, L.K.4
Roggen, E.L.5
-
39
-
-
14844351310
-
Vaccination for birch pollen allergy: Comparison of the affinities of specific immunoglobulins E, G1 and G4 measured by surface plasmon resonance
-
DOI 10.1111/j.1365-2222.2005.02160.x
-
Jakobsen CG, Bodtger U, Poulsen LK, Roggen EL (2005) Vaccination for birch pollen allergy: comparison of the affinities of specific immunoglobulins E, G1 and G4 measured by surface plasmon resonance. Clin Exp Allergy 35(2):193-198 (Pubitemid 40353782)
-
(2005)
Clinical and Experimental Allergy
, vol.35
, Issue.2
, pp. 193-198
-
-
Jakobsen, C.G.1
Bodtger, U.2
Poulsen, L.K.3
Roggen, E.L.4
-
40
-
-
34748865088
-
Antibody therapeutics: Isotype and glycoform selection
-
DOI 10.1517/14712598.7.9.1401
-
Jefferis R (2007) Antibody therapeutics: isotype and glycoform selection. Expert Opin Biol Ther 7(9):1401-1413 (Pubitemid 47475656)
-
(2007)
Expert Opinion on Biological Therapy
, vol.7
, Issue.9
, pp. 1401-1413
-
-
Jefferis, R.1
-
41
-
-
61649087668
-
Glycosylation as a strategy to improve antibody-based therapeutics
-
Jefferis R (2009a) Glycosylation as a strategy to improve antibody-based therapeutics. Nat Rev Drug Discov 8(3):226-234
-
(2009)
Nat Rev Drug Discov
, vol.8
, Issue.3
, pp. 226-234
-
-
Jefferis, R.1
-
42
-
-
67649394336
-
Recombinant antibody therapeutics: The impact of glycosylation on mechanisms of action
-
Jefferis R (2009b) Recombinant antibody therapeutics: the impact of glycosylation on mechanisms of action. Trends Pharmacol Sci 30(7):356-362
-
(2009)
Trends Pharmacol Sci
, vol.30
, Issue.7
, pp. 356-362
-
-
Jefferis, R.1
-
43
-
-
0033981703
-
Cord blood levels of immunoglobulin G subclass antibodies to food and inhalant allergens in relation to maternal atopy and the development of atopic disease during the first 8 years of life
-
DOI 10.1046/j.1365-2222.2000.00771.x
-
Jenmalm MC, Bjorksten B (2000) Cord blood levels of immunoglobulin G subclass antibodies to food and inhalant allergens in relation to maternal atopy and the development of atopic disease during the first 8 years of life. Clin Exp Allergy 30(1):34-40 (Pubitemid 30093878)
-
(2000)
Clinical and Experimental Allergy
, vol.30
, Issue.1
, pp. 34-40
-
-
Jenmalm, M.C.1
Bjorksten, B.2
-
44
-
-
24644509434
-
Allergen-specific immunotherapy with recombinant grass pollen allergens
-
DOI 10.1016/j.jaci.2005.06.004, PII S0091674905014867
-
Jutel M, Jaeger L, Suck R, Meyer H, Fiebig H, Cromwell O (2005) Allergen-specific immunotherapy with recombinant grass pollen allergens. J Allergy Clin Immunol 116(3): 608-613 (Pubitemid 41267135)
-
(2005)
Journal of Allergy and Clinical Immunology
, vol.116
, Issue.3
, pp. 608-613
-
-
Jutel, M.1
Jaeger, L.2
Suck, R.3
Meyer, H.4
Fiebig, H.5
Cromwell, O.6
-
45
-
-
70349751393
-
Selection of recombinant IgE antibodies binding the beta-lactoglobulin allergen in a conformation-dependent manner
-
Jylha S, Makinen-Kiljunen S, Haahtela T, Soderlund H, Takkinen K, Laukkanen ML (2009) Selection of recombinant IgE antibodies binding the beta-lactoglobulin allergen in a conformation-dependent manner. J Immunol Methods 350(1-2):63-70
-
(2009)
J Immunol Methods
, vol.350
, Issue.1-2
, pp. 63-70
-
-
Jylha, S.1
Makinen-Kiljunen, S.2
Haahtela, T.3
Soderlund, H.4
Takkinen, K.5
Laukkanen, M.L.6
-
46
-
-
37549011828
-
Guided selection of human antibody light chains against TAG-72 using a phage display chain shuffling approach
-
Kim SJ, Hong HJ (2007) Guided selection of human antibody light chains against TAG-72 using a phage display chain shuffling approach. J Microbiol 45(6):572-577
-
(2007)
J Microbiol
, vol.45
, Issue.6
, pp. 572-577
-
-
Kim, S.J.1
Hong, H.J.2
-
47
-
-
27144509153
-
Specific immunotherapy with recombinant brich pollen allergen rBet v 1-FV is clinically efficacious
-
Klimek L, Bachert C, Doemer C, Meyer H, Narkus A (2005) Specific immunotherapy with recombinant brich pollen allergen rBet v 1-FV is clinically efficacious. Allergy Clin Immunol Int (suppl 1):15
-
(2005)
Allergy Clin Immunol Int
, Issue.SUPPL. 1
, pp. 15
-
-
Klimek, L.1
Bachert, C.2
Doemer, C.3
Meyer, H.4
Narkus, A.5
-
48
-
-
0035045651
-
Promiscuous use of light chains by human IgE antibodies specific for three major grass pollen allergens
-
DOI 10.1159/000053660
-
Laffer S, Steinberger P, Kraft D, Valenta R (2001) Promiscuous use of light chains by human IgE antibodies specific for three major grass pollen allergens. Int Arch Allergy Immunol 124(1-3): 29-30 (Pubitemid 32304753)
-
(2001)
International Archives of Allergy and Immunology
, vol.124
, Issue.1-3
, pp. 29-30
-
-
Laffer, S.1
Steinberger, P.2
Kraft, D.3
Valenta, R.4
-
49
-
-
33749016485
-
Immunological mechanisms of allergen-specific immunotherapy
-
DOI 10.1038/nri1934, PII NRI1934
-
Larche M, Akdis CA, Valenta R (2006) Immunological mechanisms of allergen-specific immunotherapy. Nat Rev Immunol 6(10):761-771 (Pubitemid 44453462)
-
(2006)
Nature Reviews Immunology
, vol.6
, Issue.10
, pp. 761-771
-
-
Larche, M.1
Akdis, C.A.2
Valenta, R.3
-
50
-
-
17344388013
-
Immunologic characterization of monoclonal antibodies that modulate human IgE binding to the major birch pollen allergen Bet v 1
-
DOI 10.1016/S0091-6749(97)70056-3
-
Lebecque S, Dolecek C, Laffer S, Visco V, Denepoux S, Pin JJ, Guret C, Boltz-Nitulescu G, Weyer A, Valenta R (1997) Immunologic characterization of monoclonal antibodies that modulate human IgE binding to the major birch pollen allergen Bet v 1. J Allergy Clin Immunol 99(3):374-384 (Pubitemid 27123918)
-
(1997)
Journal of Allergy and Clinical Immunology
, vol.99
, Issue.3
, pp. 374-384
-
-
Lebecque, S.1
Dolecek, C.2
Laffer, S.3
Visco, V.4
Denepoux, S.5
Pin, J.-J.6
Guret, C.7
Boltz-Nitulescu, G.8
Weyer, A.9
Valenta, R.10
-
51
-
-
53049108650
-
Crystal structure of a dimerized cockroach allergen Bla g 2 complexed with a monoclonal antibody
-
Li M, Gustchina A, Alexandratos J, Wlodawer A, Wunschmann S, Kepley CL, Chapman MD, Pomes A (2008) Crystal structure of a dimerized cockroach allergen Bla g 2 complexed with a monoclonal antibody. J Biol Chem 283(33):22806-22814
-
(2008)
J Biol Chem
, vol.283
, Issue.33
, pp. 22806-22814
-
-
Li, M.1
Gustchina, A.2
Alexandratos, J.3
Wlodawer, A.4
Wunschmann, S.5
Kepley, C.L.6
Chapman, M.D.7
Pomes, A.8
-
52
-
-
0002866703
-
Immunological studies of pollinosis. I. The presence of two antibodies related to the same pollen antigen in the serum of treated hay fever patients
-
Loveless M (1940) Immunological studies of pollinosis. I. The presence of two antibodies related to the same pollen antigen in the serum of treated hay fever patients. J Immunol 38:25-50
-
(1940)
J Immunol
, vol.38
, pp. 25-50
-
-
Loveless, M.1
-
53
-
-
34248226333
-
The mast cell IgG receptors and their roles in tissue inflammation
-
DOI 10.1111/j.1600-065X.2007.00510.x
-
Malbec O, Daeron M (2007) The mast cell IgG receptors and their roles in tissue inflammation. Immunol Rev 217:206-221 (Pubitemid 46718144)
-
(2007)
Immunological Reviews
, vol.217
, Issue.1
, pp. 206-221
-
-
Malbec, O.1
Daeron, M.2
-
54
-
-
0025226085
-
Phage antibodies: Filamentous phage displaying antibody variable domains
-
McCafferty J, Griffiths AD, Winter G, Chiswell DJ (1990) Phage antibodies: filamentous phage displaying antibody variable domains. Nature 348(6301):552-554 (Pubitemid 120015109)
-
(1990)
Nature
, vol.348
, Issue.6301
, pp. 552-554
-
-
McCafferty, J.1
Griffiths, A.D.2
Winter, G.3
Chiswell, D.J.4
-
55
-
-
38949131194
-
A mouse Fcgamma-Fcepsilon protein that inhibits mast cells through activation of FcgammaRIIB, SH2 domain-containing inositol phosphatase 1, and SH2 domain-containing protein tyrosine phosphatases
-
Mertsching E, Bafetti L, Hess H, Perper S, Giza K, Allen LC, Negrou E, Hathaway K, Hopp J, Chung J, Perret D, Shields M, Saxon A, Kehry MR (2008) A mouse Fcgamma-Fcepsilon protein that inhibits mast cells through activation of FcgammaRIIB, SH2 domain-containing inositol phosphatase 1, and SH2 domain-containing protein tyrosine phosphatases. J Allergy Clin Immunol 121(2):441-447
-
(2008)
J Allergy Clin Immunol
, vol.121
, Issue.2
, pp. 441-447
-
-
Mertsching, E.1
Bafetti, L.2
Hess, H.3
Perper, S.4
Giza, K.5
Allen, L.C.6
Negrou, E.7
Hathaway, K.8
Hopp, J.9
Chung, J.10
Perret, D.11
Shields, M.12
Saxon, A.13
Kehry, M.R.14
-
56
-
-
0034235234
-
Dominant epitopes and allergic cross-reactivity: Complex formation between a Fab fragment of a monoclonal murine IgG antibody and the major allergen from birch pollen bet v 1
-
Mirza O, Henriksen A, Ipsen H, Larsen JN, Wissenbach M, Spangfort MD, Gajhede M (2000) Dominant epitopes and allergic cross-reactivity: complex formation between a Fab fragment of a monoclonal murine IgG antibody and the major allergen from birch pollen Bet v 1. J Immunol 165(1):331-338 (Pubitemid 30429524)
-
(2000)
Journal of Immunology
, vol.165
, Issue.1
, pp. 331-338
-
-
Mirza, O.1
Henriksen, A.2
Ipsen, H.3
Larsen, J.N.4
Wissenbach, M.5
Spangfort, M.D.6
Gajhede, M.7
-
57
-
-
33745092820
-
Allergen-specific polyclonal antibodies reduce allergic disease in a mouse model of allergic asthma
-
DOI 10.1159/000093283
-
Moerch U, Haahr Hansen M, Vest Hansen NJ, Rasmussen LK, Oleksiewicz MB, Frandsen TP, Haurum JS, Bregenholt S (2006) Allergen-specific polyclonal antibodies reduce allergic disease in a mouse model of allergic asthma. Int Arch Allergy Immunol 140(3):261-269 (Pubitemid 43883140)
-
(2006)
International Archives of Allergy and Immunology
, vol.140
, Issue.3
, pp. 261-269
-
-
Moerch, U.1
Hansen, H.M.2
Vest Hansen, N.J.3
Rasmussen, L.K.4
Oleksiewicz, M.B.5
Frandsen, T.P.6
Haurum, J.S.7
Bregenholt, S.8
-
58
-
-
0043264799
-
Allergen-specific immunotherapy with a monophosphoryl lipid A-adjuvanted vaccine: Reduced seasonally boosted immunoglobulin E production and inhibition of basophil histamine release by therapy-induced blocking antibodies
-
DOI 10.1046/j.1365-2222.2003.01699.x
-
Mothes N, Heinzkill M, Drachenberg KJ, Sperr WR, Krauth MT, Majlesi Y, Semper H, Valent P, Niederberger V, Kraft D, Valenta R (2003) Allergen-specific immunotherapy with a monophosphoryl lipid A-adjuvanted vaccine: reduced seasonally boosted immunoglobulin E production and inhibition of basophil histamine release by therapy-induced blocking antibodies. Clin Exp Allergy 33(9):1198-1208 (Pubitemid 37108522)
-
(2003)
Clinical and Experimental Allergy
, vol.33
, Issue.9
, pp. 1198-1208
-
-
Mothes, N.1
Heinzkill, M.2
Drachenberg, K.J.3
Sperr, W.R.4
Krauth, M.T.5
Majlesi, Y.6
Semper, H.7
Valent, P.8
Niederberger, V.9
Kraft, D.10
Valenta, R.11
-
59
-
-
0022616683
-
Combined active and passive immunotherapy in honeybee-sting allergy
-
Muller UR, Morris T, Bischof M, Friedli H, Skarvil F (1986) Combined active and passive immunotherapy in honeybee-sting allergy. J Allergy Clin Immunol 78(1 Pt 1):115-122 (Pubitemid 16099933)
-
(1986)
Journal of Allergy and Clinical Immunology
, vol.78
, Issue.I1
, pp. 115-122
-
-
Muller, U.R.1
Morris, T.2
Bischof, M.3
-
60
-
-
5144222703
-
Vaccination with genetically engineered allergens prevents progression of allergic disease
-
DOI 10.1073/pnas.0404735101
-
Niederberger V, Horak F, Vrtala S, Spitzauer S, Krauth MT, Valent P, Reisinger J, Pelzmann M, Hayek B, Kronqvist M, Gafvelin G, Gronlund H, Purohit A, Suck R, Fiebig H, Cromwell O, Pauli G, van Hage-Hamsten M, Valenta R (2004) Vaccination with genetically engineered allergens prevents progression of allergic disease. Proc Natl Acad Sci USA 101(suppl 2):14677-14682 (Pubitemid 39346742)
-
(2004)
Proceedings of the National Academy of Sciences of the United States of America
, vol.101
, Issue.SUPPL. 2
, pp. 14677-14682
-
-
Niederberger, V.1
Horak, F.2
Vrtala, S.3
Spitzauer, S.4
Krauth, M.-T.5
Valent, P.6
Reisinger, J.7
Pelzmann, M.8
Hayek, B.9
Kronqvist, M.10
Gafvelin, G.11
Gronlund, H.12
Purohit, A.13
Suck, R.14
Fiebig, H.15
Cromwell, O.16
Pauli, G.17
Van Hage-Hamsten, M.18
Valenta, R.19
-
61
-
-
34047152536
-
Vaccination with genetically modified birch pollen allergens: Immune and clinical effects on oral allergy syndrome
-
DOI 10.1016/j.jaci.2006.12.661, PII S0091674907001650
-
Niederberger V, Reisinger J, Valent P, Krauth MT, Pauli G, van Hage M, Cromwell O, Horak F, Valenta R (2007a) Vaccination with genetically modified birch pollen allergens: immune and clinical effects on oral allergy syndrome. J Allergy Clin Immunol 119(4):1013-1016 (Pubitemid 46546426)
-
(2007)
Journal of Allergy and Clinical Immunology
, vol.119
, Issue.4
, pp. 1013-1016
-
-
Niederberger, V.1
Reisinger, J.2
Valent, P.3
Krauth, M.-T.4
Pauli, G.5
Van Hage, M.6
Cromwell, O.7
Horak, F.8
Valenta, R.9
-
62
-
-
33846239232
-
Antigens drive memory IgE responses in human allergy via the nasal mucosa
-
DOI 10.1159/000096439
-
Niederberger V, Ring J, Rakoski J, Jager S, Spitzauer S, Valent P, Horak F, Kundi M, Valenta R (2007b) Antigens drive memory IgE responses in human allergy via the nasal mucosa. Int Arch Allergy Immunol 142(2):133-144 (Pubitemid 46095925)
-
(2007)
International Archives of Allergy and Immunology
, vol.142
, Issue.2
, pp. 133-144
-
-
Niederberger, V.1
Ring, J.2
Rakoski, J.3
Jager, S.4
Spitzauer, S.5
Valent, P.6
Horak, F.7
Kundi, M.8
Valenta, R.9
-
63
-
-
35748953107
-
Molecular Interactions between a Recombinant IgE Antibody and the β-Lactoglobulin Allergen
-
DOI 10.1016/j.str.2007.09.012, PII S0969212607003383
-
Niemi M, Jylha S, Laukkanen ML, Soderlund H, Makinen-Kiljunen S, Kallio JM, Hakulinen N, Haahtela T, Takkinen K, Rouvinen J (2007) Molecular interactions between a recombinant IgE antibody and the beta-lactoglobulin allergen. Structure 15(11):1413-1421 (Pubitemid 350051924)
-
(2007)
Structure
, vol.15
, Issue.11
, pp. 1413-1421
-
-
Niemi, M.1
Jylha, S.2
Laukkanen, M.-L.3
Soderlund, H.4
Makinen-Kiljunen, S.5
Kallio, J.M.6
Hakulinen, N.7
Haahtela, T.8
Takkinen, K.9
Rouvinen, J.10
-
64
-
-
34047171268
-
Identification of a B-cell Epitope of Hyaluronidase, a Major Bee Venom Allergen, from its Crystal Structure in Complex with a Specific Fab
-
DOI 10.1016/j.jmb.2007.02.036, PII S0022283607002173
-
Padavattan S, Schirmer T, Schmidt M, Akdis C, Valenta R, Mittermann I, Soldatova L, Slater J, Mueller U, Markovic-Housley Z (2007) Identification of a B-cell epitope of hyaluronidase, a major bee venom allergen, from its crystal structure in complex with a specific Fab. J Mol Biol 368(3):742-752 (Pubitemid 46527617)
-
(2007)
Journal of Molecular Biology
, vol.368
, Issue.3
, pp. 742-752
-
-
Padavattan, S.1
Schirmer, T.2
Schmidt, M.3
Akdis, C.4
Valenta, R.5
Mittermann, I.6
Soldatova, L.7
Slater, J.8
Mueller, U.9
Markovic-Housley, Z.10
-
65
-
-
61449212919
-
High-affinity IgE recognition of a conformational epitope of the major respiratory allergen Phl p 2 as revealed by X-ray crystallography
-
Padavattan S, Flicker S, Schirmer T, Madritsch C, Randow S, Reese G, Vieths S, Lupinek C, Ebner C, Valenta R, Markovic-Housley Z (2009) High-affinity IgE recognition of a conformational epitope of the major respiratory allergen Phl p 2 as revealed by X-ray crystallography. J Immunol 182(4):2141-2151
-
(2009)
J Immunol
, vol.182
, Issue.4
, pp. 2141-2151
-
-
Padavattan, S.1
Flicker, S.2
Schirmer, T.3
Madritsch, C.4
Randow, S.5
Reese, G.6
Vieths, S.7
Lupinek, C.8
Ebner, C.9
Valenta, R.10
Markovic-Housley, Z.11
-
66
-
-
49149107253
-
Efficacy of recombinant birch pollen vaccine for the treatment of birch-allergic rhinoconjunctivitis
-
Pauli G, Larsen TH, Rak S, Horak F, Pastorello E, Valenta R, Purohit A, Arvidsson M, Kavina A, Schroeder JW, Mothes N, Spitzauer S, Montagut A, Galvain S, Melac M, Andre C, Poulsen LK, Malling HJ (2008) Efficacy of recombinant birch pollen vaccine for the treatment of birch-allergic rhinoconjunctivitis. J Allergy Clin Immunol 122(5):951-960
-
(2008)
J Allergy Clin Immunol
, vol.122
, Issue.5
, pp. 951-960
-
-
Pauli, G.1
Larsen, T.H.2
Rak, S.3
Horak, F.4
Pastorello, E.5
Valenta, R.6
Purohit, A.7
Arvidsson, M.8
Kavina, A.9
Schroeder, J.W.10
Mothes, N.11
Spitzauer, S.12
Montagut, A.13
Galvain, S.14
Melac, M.15
Andre, C.16
Poulsen, L.K.17
Malling, H.J.18
-
67
-
-
33344476078
-
A focused antibody library for improved hapten recognition
-
DOI 10.1016/j.jmb.2006.01.004, PII S0022283606000209
-
Persson H, Lantto J, Ohlin M (2006) A focused antibody library for improved hapten recognition. J Mol Biol 357(2):607-620 (Pubitemid 43290759)
-
(2006)
Journal of Molecular Biology
, vol.357
, Issue.2
, pp. 607-620
-
-
Persson, H.1
Lantto, J.2
Ohlin, M.3
-
68
-
-
47649099663
-
In vitro evolution of an antibody fragment population to find high-affinity hapten binders
-
DOI 10.1093/protein/gzn024
-
Persson H, Wallmark H, Ljungars A, Hallborn J, Ohlin M (2008) In vitro evolution of an antibody fragment population to find high-affinity hapten binders. Protein Eng Des Sel 21(8):485-493 (Pubitemid 352019919)
-
(2008)
Protein Engineering, Design and Selection
, vol.21
, Issue.8
, pp. 485-493
-
-
Persson, H.1
Wallmark, H.2
Ljungars, A.3
Hallborn, J.4
Ohlin, M.5
-
69
-
-
0023774406
-
Immunotherapy with partially purified and standardized tree pollen extracts. I. Clinical results from a three-year double-blind study of patients treated with pollen extracts either of birch or combinations of alder, birch and hazel
-
Petersen BN, Janniche H, Munch EP, Wihl JA, Bowadt H, Ipsen H, Lowenstein H (1988) Immunotherapy with partially purified and standardized tree pollen extracts. I. Clinical results from a three-year double-blind study of patients treated with pollen extracts either of birch or combinations of alder, birch and hazel. Allergy 43(5):353-362
-
(1988)
Allergy
, vol.43
, Issue.5
, pp. 353-362
-
-
Petersen, B.N.1
Janniche, H.2
Munch, E.P.3
Wihl, J.A.4
Bowadt, H.5
Ipsen, H.6
Lowenstein, H.7
-
70
-
-
33845364560
-
Enhanced half-life of genetically engineered human IgG1 antibodies in a humanized FcRn mouse model: Potential application in humorally mediated autoimmune disease
-
DOI 10.1093/intimm/dxl110
-
Petkova SB, Akilesh S, Sproule TJ, Christianson GJ, Al Khabbaz H, Brown AC, Presta LG, Meng YG, Roopenian DC (2006) Enhanced half-life of genetically engineered human IgG1 antibodies in a humanized FcRn mouse model: potential application in humorally mediated autoimmune disease. Int Immunol 18(12):1759-1769 (Pubitemid 44884038)
-
(2006)
International Immunology
, vol.18
, Issue.12
, pp. 1759-1769
-
-
Petkova, S.B.1
Akilesh, S.2
Sproule, T.J.3
Christianson, G.J.4
Al Khabbaz, H.5
Brown, A.C.6
Presta, L.G.7
Meng, Y.G.8
Roopenian, D.C.9
-
71
-
-
56549103486
-
Maternal tolerance achieved during pregnancy is transferred to the offspring via breast milk and persistently protects the offspring from allergic asthma
-
Polte T, Hansen G (2008) Maternal tolerance achieved during pregnancy is transferred to the offspring via breast milk and persistently protects the offspring from allergic asthma. Clin Exp Allergy 38(12):1950-1958
-
(2008)
Clin Exp Allergy
, vol.38
, Issue.12
, pp. 1950-1958
-
-
Polte, T.1
Hansen, G.2
-
72
-
-
55449099354
-
Allergy prevention starts before conception: Mater-nofetal transfer of tolerance protects against the development of asthma
-
e5
-
Polte T, Hennig C, Hansen G (2008) Allergy prevention starts before conception: mater-nofetal transfer of tolerance protects against the development of asthma. J Allergy Clin Immunol 122(5):1022-1030 e5
-
(2008)
J Allergy Clin Immunol
, vol.122
, Issue.5
, pp. 1022-1030
-
-
Polte, T.1
Hennig, C.2
Hansen, G.3
-
73
-
-
0001391552
-
Studien über die Überempfindlichkeit
-
Prausnitz C, Küstner H (1921) Studien über die Überempfindlichkeit. Zbl Bakt 86:160-169
-
(1921)
Zbl Bakt
, vol.86
, pp. 160-169
-
-
Prausnitz, C.1
Küstner, H.2
-
74
-
-
38449117854
-
Analysis of epitope-specific immune responses induced by vaccination with structurally folded and unfolded recombinant Bet v 1 allergen derivatives in man
-
Pree I, Reisinger J, Focke M, Vrtala S, Pauli G, van Hage M, Cromwell O, Gadermaier E, Egger C, Reider N, Horak F, Valenta R, Niederberger V (2007) Analysis of epitope-specific immune responses induced by vaccination with structurally folded and unfolded recombinant Bet v 1 allergen derivatives in man. J Immunol 179(8):5309-5316
-
(2007)
J Immunol
, vol.179
, Issue.8
, pp. 5309-5316
-
-
Pree, I.1
Reisinger, J.2
Focke, M.3
Vrtala, S.4
Pauli, G.5
Van Hage, M.6
Cromwell, O.7
Gadermaier, E.8
Egger, C.9
Reider, N.10
Horak, F.11
Valenta, R.12
Niederberger, V.13
-
75
-
-
77955380658
-
Inhibition of CD23-dependent facilitated allergen binding to B cells following vaccination with genetically modified hypoallergenic Bet v 1 molecules
-
Pree I, Shamji MH, Kimber I, Valenta R, Durham SR, Niederberger V (2010) Inhibition of CD23-dependent facilitated allergen binding to B cells following vaccination with genetically modified hypoallergenic Bet v 1 molecules. Clin Exp Allergy 40(9):1346-1352
-
(2010)
Clin Exp Allergy
, vol.40
, Issue.9
, pp. 1346-1352
-
-
Pree, I.1
Shamji, M.H.2
Kimber, I.3
Valenta, R.4
Durham, S.R.5
Niederberger, V.6
-
76
-
-
33747616656
-
Engineering of therapeutic antibodies to minimize immunogenicity and optimize function
-
DOI 10.1016/j.addr.2006.01.026, PII S0169409X06000858
-
Presta LG (2006) Engineering of therapeutic antibodies to minimize immunogenicity and optimize function. Adv Drug Deliv Rev 58(5-6):640-656 (Pubitemid 44262411)
-
(2006)
Advanced Drug Delivery Reviews
, vol.58
, Issue.5-6
, pp. 640-656
-
-
Presta, L.G.1
-
77
-
-
48549105161
-
Molecular engineering and design of therapeutic antibodies
-
Presta LG (2008) Molecular engineering and design of therapeutic antibodies. Curr Opin Immunol 20(4):460-470
-
(2008)
Curr Opin Immunol
, vol.20
, Issue.4
, pp. 460-470
-
-
Presta, L.G.1
-
78
-
-
46849121475
-
Clinical effects of immunotherapy with genetically modified recombinant birch pollen Bet v 1 derivatives
-
Purohit A, Niederberger V, Kronqvist M, Horak F, Gronneberg R, Suck R, Weber B, Fiebig H, van Hage M, Pauli G, Valenta R, Cromwell O (2008) Clinical effects of immunotherapy with genetically modified recombinant birch pollen Bet v 1 derivatives. Clin Exp Allergy 38(9):1514-1525
-
(2008)
Clin Exp Allergy
, vol.38
, Issue.9
, pp. 1514-1525
-
-
Purohit, A.1
Niederberger, V.2
Kronqvist, M.3
Horak, F.4
Gronneberg, R.5
Suck, R.6
Weber, B.7
Fiebig, H.8
Van Hage, M.9
Pauli, G.10
Valenta, R.11
Cromwell, O.12
-
79
-
-
41449094497
-
Allergens are distributed into few protein families and possess a restricted number of biochemical functions
-
e7
-
Radauer C, Bublin M, Wagner S, Mari A, Breiteneder H (2008) Allergens are distributed into few protein families and possess a restricted number of biochemical functions. J Allergy Clin Immunol 121(4):847-852 e7
-
(2008)
J Allergy Clin Immunol
, vol.121
, Issue.4
, pp. 847-852
-
-
Radauer, C.1
Bublin, M.2
Wagner, S.3
Mari, A.4
Breiteneder, H.5
-
80
-
-
7944222460
-
Light-chain shuffling results in successful phage display selection of functional prokaryotic-expressed antibody fragments to N-glycolyl GM3 ganglioside
-
DOI 10.1016/j.jim.2004.07.002, PII S0022175904002376
-
Rojas G, Talavera A, Munoz Y, Rengifo E, Krengel U, Angstrom J, Gavilondo J, Moreno E (2004) Light-chain shuffling results in successful phage display selection of functional prokaryotic-expressed antibody fragments to N-glycolyl GM3 ganglioside. J Immunol Methods 293(1-2):71-83 (Pubitemid 39468333)
-
(2004)
Journal of Immunological Methods
, vol.293
, Issue.1-2
, pp. 71-83
-
-
Rojas, G.1
Talavera, A.2
Munoz, Y.3
Rengifo, E.4
Krengel, U.5
Angstrom, J.6
Gavilondo, J.7
Moreno, E.8
-
81
-
-
34548229364
-
FcRn: The neonatal Fc receptor comes of age
-
DOI 10.1038/nri2155, PII NRI2155
-
Roopenian DC, Akilesh S (2007) FcRn: the neonatal Fc receptor comes of age. Nat Rev Immunol 7(9):715-725 (Pubitemid 47327396)
-
(2007)
Nature Reviews Immunology
, vol.7
, Issue.9
, pp. 715-725
-
-
Roopenian, D.C.1
Akilesh, S.2
-
82
-
-
0033829661
-
Antibodies for the prevention and treatment of viral diseases
-
Sawyer LA (2000) Antibodies for the prevention and treatment of viral diseases. Antiviral Res 47(2):57-77
-
(2000)
Antiviral Res
, vol.47
, Issue.2
, pp. 57-77
-
-
Sawyer, L.A.1
-
83
-
-
0041633800
-
Airway IgG counteracts specific and bystander allergen-triggered pulmonary inflammation by a mechanism dependent on FcγR and IFN-γ
-
Sehra S, Pynaert G, Tournoy K, Haegeman A, Matthys P, Tagawa Y, Pauwels R, Grooten J (2003) Airway IgG counteracts specific and bystander allergen-triggered pulmonary inflammation by a mechanism dependent on Fc gamma R and IFN-gamma. J Immunol 171(4):2080-2089 (Pubitemid 36966492)
-
(2003)
Journal of Immunology
, vol.171
, Issue.4
, pp. 2080-2089
-
-
Sehra, S.1
Pynaert, G.2
Tournoy, K.3
Haegeman, A.4
Matthys, P.5
Tagawa, Y.6
Pauwels, R.7
Grooten, J.8
-
84
-
-
0029919595
-
Construction of a combinatorial IgE library from an allergic patient. Isolation and characterization of human IgE Fabs with specificity for the major timothy grass pollen allergen, Phl p 5
-
Steinberger P, Kraft D, Valenta R (1996) Construction of a combinatorial IgE library from an allergic patient. Isolation and characterization of human IgE Fabs with specificity for the major timothy grass pollen allergen, Phl p 5. J Biol Chem 271(18):10967-10972
-
(1996)
J Biol Chem
, vol.271
, Issue.18
, pp. 10967-10972
-
-
Steinberger, P.1
Kraft, D.2
Valenta, R.3
-
85
-
-
33644638676
-
IgG-blocking antibodies inhibit IgE-mediated anaphylaxis in vivo through both antigen interception and FcγRIIb cross-linking
-
DOI 10.1172/JCI25575
-
Strait RT, Morris SC, Finkelman FD (2006) IgG-blocking antibodies inhibit IgE-mediated anaphylaxis in vivo through both antigen interception and Fc gamma RIIb cross-linking. J Clin Invest 116(3):833-841 (Pubitemid 43326893)
-
(2006)
Journal of Clinical Investigation
, vol.116
, Issue.3
, pp. 833-841
-
-
Strait, R.T.1
Morris, S.C.2
Finkelman, F.D.3
-
86
-
-
3042778582
-
A bispecific antibody against human IgE and human FcγRII that inhibits antigen-induced histamine release by human mast cells and basophils
-
DOI 10.1111/j.1398-9995.2004.00332.x
-
Tam SW, Demissie S, Thomas D, Daeron M (2004) A bispecific antibody against human IgE and human FcgammaRII that inhibits antigen-induced histamine release by human mast cells and basophils. Allergy 59(7):772-780 (Pubitemid 38850354)
-
(2004)
Allergy: European Journal of Allergy and Clinical Immunology
, vol.59
, Issue.7
, pp. 772-780
-
-
Tam, S.W.1
Demissie, S.2
Thomas, D.3
Daeron, M.4
-
87
-
-
77955922546
-
Mechanisms of allergen-specific desensitization
-
Uermosi C, Beerli RR, Bauer M, Manolova V, Dietmeier K, Buser RB, Kundig TM, Saudan P, Bachmann MF (2010) Mechanisms of allergen-specific desensitization. J Allergy Clin Immunol 126(2):375-383
-
(2010)
J Allergy Clin Immunol
, vol.126
, Issue.2
, pp. 375-383
-
-
Uermosi, C.1
Beerli, R.R.2
Bauer, M.3
Manolova, V.4
Dietmeier, K.5
Buser, R.B.6
Kundig, T.M.7
Saudan, P.8
Bachmann, M.F.9
-
88
-
-
0141886182
-
Critical role of preconceptional immunization for protective and nonpathological specific immunity in murine neonates
-
Uthoff H, Spenner A, Reckelkamm W, Ahrens B, Wolk G, Hackler R, Hardung F, Schaefer J, Scheffold A, Renz H, Herz U (2003) Critical role of preconceptional immunization for protective and nonpathological specific immunity in murine neonates. J Immunol 171(7):3485-3492 (Pubitemid 37254550)
-
(2003)
Journal of Immunology
, vol.171
, Issue.7
, pp. 3485-3492
-
-
Uthoff, H.1
Spenner, A.2
Reckelkamm, W.3
Ahrens, B.4
Wolk, G.5
Hackler, R.6
Hardung, F.7
Schaefer, J.8
Scheffold, A.9
Renz, H.10
Herz, U.11
-
89
-
-
0029586091
-
Recombinant allergens for diagnosis and therapy of allergic diseases
-
DOI 10.1016/0952-7915(95)80043-3
-
Valenta R, Kraft D (1995) Recombinant allergens for diagnosis and therapy of allergic diseases. Curr Opin Immunol 7(6):751-756 (Pubitemid 26038513)
-
(1995)
Current Opinion in Immunology
, vol.7
, Issue.6
, pp. 751-756
-
-
Valenta, R.1
Kraft, D.2
-
90
-
-
0036888370
-
From allergen structure to new forms of allergen-specific immunotherapy
-
DOI 10.1016/S0952-7915(02)00402-8
-
Valenta R, Kraft D (2002) From allergen structure to new forms of allergen-specific immunotherapy. Curr Opin Immunol 14(6):718-727 (Pubitemid 35292418)
-
(2002)
Current Opinion in Immunology
, vol.14
, Issue.6
, pp. 718-727
-
-
Valenta, R.1
Kraft, D.2
-
91
-
-
0029978549
-
Immunological and structural similarities among allergens: Prerequisite for a specific and component-based therapy of allergy
-
Valenta R, Steinberger P, Duchene M, Kraft D (1996) Immunological and structural similarities among allergens: prerequisite for a specific and component-based therapy of allergy. Immunol Cell Biol 74(2):187-194 (Pubitemid 26173825)
-
(1996)
Immunology and Cell Biology
, vol.74
, Issue.2
, pp. 187-194
-
-
Valenta, R.1
Steinberger, P.2
Duchene, M.3
Kraft, D.4
-
92
-
-
77952301906
-
From allergen genes to allergy vaccines
-
Valenta R, Ferreira F, Focke-Tejkl M, Linhart B, Niederberger V, Swoboda I, Vrtala S (2010) From allergen genes to allergy vaccines. Ann Rev Immunol 28:211-214
-
(2010)
Ann Rev Immunol
, vol.28
, pp. 211-214
-
-
Valenta, R.1
Ferreira, F.2
Focke-Tejkl, M.3
Linhart, B.4
Niederberger, V.5
Swoboda, I.6
Vrtala, S.7
-
93
-
-
0033197966
-
+ T cells by inhibiting serum-IgE-facilitated allergen presentation
-
Van Neerven RJ, Wikborg T, Lund G, Jacobsen B, Brinch-Nielsen A, Arnved J, Ipsen H (1999) Blocking antibodies induced by specific allergy vaccination prevent the activation of CD4+ T cells by inhibiting serum-IgE-facilitated allergen presentation. J Immunol 163(5):2944-2952 (Pubitemid 29399227)
-
(1999)
Journal of Immunology
, vol.163
, Issue.5
, pp. 2944-2952
-
-
Van Neerven, R.J.J.1
Wikborg, T.2
Lund, G.3
Jacobsen, B.4
Brinch-Nielsen, A.5
Arnved, J.6
Ipsen, H.7
-
94
-
-
1642265044
-
A double-blind, placebo-controlled birch allergy vaccination study: Inhibition of CD23-mediated serum-immunoglobulin E-facilitated allergen presentation
-
DOI 10.1111/j.1365-2222.2004.01899.x
-
Van Neerven RJ, Arvidsson M, Ipsen H, Sparholt SH, Rak S, Wurtzen PA (2004) A double-blind, placebo-controlled birch allergy vaccination study: inhibition of CD23-mediated serum-immunoglobulin E-facilitated allergen presentation. Clin Exp Allergy 34(3):420-428 (Pubitemid 38373005)
-
(2004)
Clinical and Experimental Allergy
, vol.34
, Issue.3
, pp. 420-428
-
-
Van Neerven, R.J.J.1
Arvidssont, M.2
Ipsen, H.3
Sparholt, S.H.4
Rak, S.5
Wurtzen, P.A.6
-
95
-
-
77949482579
-
Maternal immunization with ovalbumin prevents neonatal allergy development and up-regulates inhibitory receptor Fc gamma RIIB expression on B cells
-
Victor JR, Muniz BP, Fusaro AE, de Brito CA, Taniguchi EF, Duarte AJ, Sato MN (2010) Maternal immunization with ovalbumin prevents neonatal allergy development and up-regulates inhibitory receptor Fc gamma RIIB expression on B cells. BMC Immunol 11:11
-
(2010)
BMC Immunol
, vol.11
, pp. 11
-
-
Victor, J.R.1
Muniz, B.P.2
Fusaro, A.E.3
De Brito, C.A.4
Taniguchi, E.F.5
Duarte, A.J.6
Sato, M.N.7
-
96
-
-
8944234849
-
Human IgG monoclonal antibodies that modulate the binding of specific IgE to birch pollen Bet v 1
-
Visco V, Dolecek C, Denepoux S, Le Mao J, Guret C, Rousset F, Guinnepain MT, Kraft D, Valenta R, Weyer A, Banchereau J, Labecque S (1996) Human IgG monoclonal antibodies that modulate the binding of specific IgE to birch pollen Bet v 1. J Immunol 157(2):956-962 (Pubitemid 26235287)
-
(1996)
Journal of Immunology
, vol.157
, Issue.2
, pp. 956-962
-
-
Visco, V.1
Dolecek, C.2
Denepoux, S.3
Le Mao, J.4
Guret, C.5
Rousset, F.6
Guinnepain, M.-T.7
Kraft, D.8
Valenta, R.9
Weyer, A.10
Banchereau, J.11
Lebecque, S.12
-
97
-
-
0026264771
-
The mechanism of diphtheria immunity and tetanus immunity in animals 1890
-
1319-1320
-
Von Behring E, Kitasato S (1991) The mechanism of diphtheria immunity and tetanus immunity in animals. 1890. Mol Immunol 28(12):1317 1319-1320
-
(1991)
Mol Immunol
, vol.28
, Issue.12
, pp. 1317
-
-
Von Behring, E.1
Kitasato, S.2
-
99
-
-
0043258973
-
Inhibition of allergen-IgE binding to B cells by IgG antibodies after grass pollen immunotherapy
-
DOI 10.1016/S0091-6749(03)02022-0
-
Wachholz PA, Soni NK, Till SJ, Durham SR (2003) Inhibition of allergen-IgE binding to B cells by IgG antibodies after grass pollen immunotherapy. J Allergy Clin Immunol 112(5):915-922 (Pubitemid 37412059)
-
(2003)
Journal of Allergy and Clinical Immunology
, vol.112
, Issue.5
, pp. 915-922
-
-
Wachholz, P.A.1
Soni, N.K.2
Till, S.J.3
Durham, S.R.4
-
101
-
-
0032568558
-
Stepwise in vitro affinity maturation of Vitaxin, an alphav beta3-specific humanized mAb
-
Wu H, Beuerlein G, Nie Y, Smith H, Lee BA, Hensler M, Huse WD, Watkins JD (1998) Stepwise in vitro affinity maturation of Vitaxin, an alphav beta3-specific humanized mAb. Proc Natl Acad Sci USA 95(11):6037-6042
-
(1998)
Proc Natl Acad Sci USA
, vol.95
, Issue.11
, pp. 6037-6042
-
-
Wu, H.1
Beuerlein, G.2
Nie, Y.3
Smith, H.4
Lee, B.A.5
Hensler, M.6
Huse, W.D.7
Watkins, J.D.8
-
102
-
-
67649207267
-
Engineering human IgG1 affinity to human neonatal Fc receptor: Impact of affinity improvement on pharmacokinetics in primates
-
Yeung YA, Leabman MK, Marvin JS, Qiu J, Adams CW, Lien S, Starovasnik MA, Lowman HB (2009) Engineering human IgG1 affinity to human neonatal Fc receptor: impact of affinity improvement on pharmacokinetics in primates. J Immunol 182(12):7663-7671
-
(2009)
J Immunol
, vol.182
, Issue.12
, pp. 7663-7671
-
-
Yeung, Y.A.1
Leabman, M.K.2
Marvin, J.S.3
Qiu, J.4
Adams, C.W.5
Lien, S.6
Starovasnik, M.A.7
Lowman, H.B.8
-
103
-
-
4344605211
-
Inhibition of allergen-specific IgE reactivity by a human Ig Fcγ-Fcε bifunctional fusion protein
-
DOI 10.1016/j.jaci.2004.03.058, PII S0091674904014083
-
Zhang K, Kepley CL, Terada T, Zhu D, Perez H, Saxon A (2004) Inhibition of allergen-specific IgE reactivity by a human Ig Fcgamma-Fcepsilon bifunctional fusion protein. J Allergy Clin Immunol 114(2):321-327 (Pubitemid 39119031)
-
(2004)
Journal of Allergy and Clinical Immunology
, vol.114
, Issue.2
, pp. 321-327
-
-
Zhang, K.1
Kepley, C.L.2
Terada, T.3
Zhu, D.4
Perez, H.5
Saxon, A.6
-
104
-
-
0036100524
-
A novel human immunoglobulin Fcγ-Fcε bifunctional fusion protein inhibits FcεRI-mediated degranulation
-
DOI 10.1038/nm0502-518
-
Zhu D, Kepley CL, Zhang M, Zhang K, Saxon A (2002) A novel human immunoglobulin Fc gamma Fc epsilon bifunctional fusion protein inhibits Fc epsilon RI-mediated degranulation. Nat Med 8(5):518-521 (Pubitemid 34546756)
-
(2002)
Nature Medicine
, vol.8
, Issue.5
, pp. 518-521
-
-
Zhu, D.1
Kepley, C.L.2
Zhang, M.3
Zhang, K.4
Saxon, A.5
|