메뉴 건너뛰기




Volumn 116, Issue 3, 2006, Pages 833-841

IgG-blocking antibodies inhibit IgE-mediated anaphylaxis in vivo through both antigen interception and FcγRIIb cross-linking

Author keywords

[No Author keywords available]

Indexed keywords

ALLERGEN; ANTIGEN; BLOCKING ANTIBODY; EPITOPE; FC RECEPTOR IIB; FC RECEPTOR III; IMMUNOGLOBULIN ANTIBODY; IMMUNOGLOBULIN E; IMMUNOGLOBULIN G ANTIBODY; IMMUNOGLOBULIN RECEPTOR; UNCLASSIFIED DRUG;

EID: 33644638676     PISSN: 00219738     EISSN: 15588238     Source Type: Journal    
DOI: 10.1172/JCI25575     Document Type: Article
Times cited : (249)

References (54)
  • 1
    • 0141958643 scopus 로고    scopus 로고
    • Renaissance of the blocking antibody concept in type I allergy
    • Flicker, S., and Valenta, R. 2003. Renaissance of the blocking antibody concept in type I allergy. Int. Arch. Allergy Immunol. 132:13-24.
    • (2003) Int. Arch. Allergy Immunol. , vol.132 , pp. 13-24
    • Flicker, S.1    Valenta, R.2
  • 2
    • 0001944764 scopus 로고    scopus 로고
    • Allergy
    • W.E. Paul, editor. Lippincott-Raven. Philadelphia, Pennsylvania, USA
    • Galli, S., and Lantz, C. 1999. Allergy. In Fundamental immunology. W.E. Paul, editor. Lippincott-Raven. Philadelphia, Pennsylvania, USA. 1127-1174.
    • (1999) Fundamental Immunology , pp. 1127-1174
    • Galli, S.1    Lantz, C.2
  • 3
    • 0028842110 scopus 로고
    • Regulation of high-affinity IgE receptor-mediated mast cell activation by murine low-affinity IgG receptors
    • Daeron, M., Malbec, O., Latour, S., Arock, M., and Fridman, W.H. 1995. Regulation of high-affinity IgE receptor-mediated mast cell activation by murine low-affinity IgG receptors. J. Clin. Invest. 95:577-585.
    • (1995) J. Clin. Invest. , vol.95 , pp. 577-585
    • Daeron, M.1    Malbec, O.2    Latour, S.3    Arock, M.4    Fridman, W.H.5
  • 4
    • 0038664354 scopus 로고    scopus 로고
    • The effect of specific immunotherapy on T-cell receptor repertoire in patients with allergy to house-dust mite
    • Sade, K., Kivity, S., Levy, A., and Fireman, E. 2003. The effect of specific immunotherapy on T-cell receptor repertoire in patients with allergy to house-dust mite. Allergy. 58:430-434.
    • (2003) Allergy , vol.58 , pp. 430-434
    • Sade, K.1    Kivity, S.2    Levy, A.3    Fireman, E.4
  • 5
    • 0033197966 scopus 로고    scopus 로고
    • + T cells by inhibiting serum-IgE-facilitated allergen presentation
    • + T cells by inhibiting serum-IgE-facilitated allergen presentation. J. Immunol. 163:2944-2952.
    • (1999) J. Immunol. , vol.163 , pp. 2944-2952
    • Van Neerven, R.J.1
  • 6
    • 0031784380 scopus 로고    scopus 로고
    • Immunologic changes associated with allergen immunotherapy
    • Durham, S.R., and Till, S.J. 1998. Immunologic changes associated with allergen immunotherapy. J. Allergy Clin. Immunol. 102:157-164.
    • (1998) J. Allergy Clin. Immunol. , vol.102 , pp. 157-164
    • Durham, S.R.1    Till, S.J.2
  • 8
    • 0019976840 scopus 로고
    • Clinical relevance of the venom-specific immunoglobulin G antibody level during immunotherapy
    • Golden, D.B., et al. 1982. Clinical relevance of the venom-specific immunoglobulin G antibody level during immunotherapy. J. Allergy Clin. Immunol. 69:489-493.
    • (1982) J. Allergy Clin. Immunol. , vol.69 , pp. 489-493
    • Golden, D.B.1
  • 9
    • 85004788407 scopus 로고
    • Venom-specific IgE and IgG antibodies as a measure of the degree of protection in insect-sting-sensitive patients
    • Urbanek, R., Krauss, U., Ziupa, J., and Smedegard, G. 1983. Venom-specific IgE and IgG antibodies as a measure of the degree of protection in insect-sting-sensitive patients. Clin. Allergy. 13:229-234.
    • (1983) Clin. Allergy , vol.13 , pp. 229-234
    • Urbanek, R.1    Krauss, U.2    Ziupa, J.3    Smedegard, G.4
  • 10
    • 0024599075 scopus 로고
    • IgG and IgE antibodies after immunotherapy with bee and wasp venom
    • Kemeny, D.M., et al. 1989. IgG and IgE antibodies after immunotherapy with bee and wasp venom. Int. Arch. Allergy Appl. Immunol. 88:247-249.
    • (1989) Int. Arch. Allergy Appl. Immunol. , vol.88 , pp. 247-249
    • Kemeny, D.M.1
  • 11
    • 0026713346 scopus 로고
    • Clinical correlation of the venom-specific IgG antibody level during maintenance venom immunotherapy
    • Golden, D.B., et al. 1992. Clinical correlation of the venom-specific IgG antibody level during maintenance venom immunotherapy. J. Allergy Clin. Immunol. 90:386-393.
    • (1992) J. Allergy Clin. Immunol. , vol.90 , pp. 386-393
    • Golden, D.B.1
  • 12
    • 0027337596 scopus 로고
    • Venom-specific IgG antibodies in bee and wasp allergy: Lack of correlation with protection from stings
    • Ewan, P.W., Deighton, J., Wilson, A.B., and Lachmann, P.J. 1993. Venom-specific IgG antibodies in bee and wasp allergy: lack of correlation with protection from stings. Clin. Exp. Allergy. 23:647-660.
    • (1993) Clin. Exp. Allergy , vol.23 , pp. 647-660
    • Ewan, P.W.1    Deighton, J.2    Wilson, A.B.3    Lachmann, P.J.4
  • 14
    • 10744232817 scopus 로고    scopus 로고
    • Grass pollen immunotherapy induces mucosal and peripheral IL-10 responses and blocking IgG activity
    • Nouri-Aria, K.T., et al. 2004. Grass pollen immunotherapy induces mucosal and peripheral IL-10 responses and blocking IgG activity. J. Immunol. 172:3252-3259.
    • (2004) J. Immunol. , vol.172 , pp. 3252-3259
    • Nouri-Aria, K.T.1
  • 15
    • 0019985216 scopus 로고
    • Polyclonal activation of the murine immune system by an antibody to IgD. II. Generation of polyclonal antibody production and cells with surface IgG
    • Finkelman, F.D., et al. 1982. Polyclonal activation of the murine immune system by an antibody to IgD. II. Generation of polyclonal antibody production and cells with surface IgG. J. Immunol. 129:638-646.
    • (1982) J. Immunol. , vol.129 , pp. 638-646
    • Finkelman, F.D.1
  • 16
    • 0025847697 scopus 로고
    • Secondary immunoglobulin responses of BALB/c mice previously stimulated with goat anti-mouse IgD
    • Champion, B.R., Buckham, S., Page, K., Obray, H., and Zanders, E.D. 1991. Secondary immunoglobulin responses of BALB/c mice previously stimulated with goat anti-mouse IgD. Immunology. 72:336-343.
    • (1991) Immunology , vol.72 , pp. 336-343
    • Champion, B.R.1    Buckham, S.2    Page, K.3    Obray, H.4    Zanders, E.D.5
  • 17
    • 0023266170 scopus 로고
    • Polyclonal activation of the murine immune system by a goat antibody to mouse IgD. IX. Induction of a polyclonal IgE response
    • Finkelman, F.D., Snapper, C.M., Mountz, J.D., and Katona, I.M. 1987. Polyclonal activation of the murine immune system by a goat antibody to mouse IgD. IX. Induction of a polyclonal IgE response. J. Immunol. 138:2826-2830.
    • (1987) J. Immunol. , vol.138 , pp. 2826-2830
    • Finkelman, F.D.1    Snapper, C.M.2    Mountz, J.D.3    Katona, I.M.4
  • 18
    • 0026002789 scopus 로고
    • Cytokine gene expression after in vivo primary immunization with goat antibody to mouse IgD antibody
    • Svetic, A., et al. 1991. Cytokine gene expression after in vivo primary immunization with goat antibody to mouse IgD antibody. J. Immunol. 147:2391-2397.
    • (1991) J. Immunol. , vol.147 , pp. 2391-2397
    • Svetic, A.1
  • 19
    • 0023226671 scopus 로고
    • Polyclonal activation of the murine immune system by an antibody to IgD. VIII. Stimulation of IgD secretion
    • Mountz, J.D., Smith, J., Snapper, C.M., Mushinski, J.F., and Finkelman, F.D. 1987. Polyclonal activation of the murine immune system by an antibody to IgD. VIII. Stimulation of IgD secretion. J. Immunol. 139:2172-2178.
    • (1987) J. Immunol. , vol.139 , pp. 2172-2178
    • Mountz, J.D.1    Smith, J.2    Snapper, C.M.3    Mushinski, J.F.4    Finkelman, F.D.5
  • 21
    • 0025201735 scopus 로고
    • Rapid stimulation of large specific antibody responses with conjugates of antigen and anti-IgD antibody
    • Lees, A., et al. 1990. Rapid stimulation of large specific antibody responses with conjugates of antigen and anti-IgD antibody. J. Immunol. 145:3594-3600.
    • (1990) J. Immunol. , vol.145 , pp. 3594-3600
    • Lees, A.1
  • 22
    • 0031851660 scopus 로고    scopus 로고
    • Gadolinium chloride removes pulmonary intravascular macrophages and curtails the degree of ovine lentivirus-induced lymphoid interstitial pneumonia
    • Singh, B., and de la Concha-Bermejillo, A. 1998. Gadolinium chloride removes pulmonary intravascular macrophages and curtails the degree of ovine lentivirus-induced lymphoid interstitial pneumonia. Int. J. Exp. Pathol. 79:151-162.
    • (1998) Int. J. Exp. Pathol. , vol.79 , pp. 151-162
    • Singh, B.1    De La Concha-Bermejillo, A.2
  • 23
    • 0030255211 scopus 로고    scopus 로고
    • Gadolinium chloride alters the acinar distribution of phagocytosis and balance between pro- and anti-inflammatory cytokines
    • Rai, R.M., Zhang, J.X., Clemens, M.G., and Diehl, A.M. 1996. Gadolinium chloride alters the acinar distribution of phagocytosis and balance between pro- and anti-inflammatory cytokines. Shock. 6:243-247.
    • (1996) Shock , vol.6 , pp. 243-247
    • Rai, R.M.1    Zhang, J.X.2    Clemens, M.G.3    Diehl, A.M.4
  • 24
    • 0028289877 scopus 로고
    • Inhibition of anaphylactic shock by gadolinium chloride-induced Kupffer cell blockade
    • Lazar, G., Jr., et al. 1994. Inhibition of anaphylactic shock by gadolinium chloride-induced Kupffer cell blockade. Agents Actions. 41:C97-C98.
    • (1994) Agents Actions , vol.41
    • Lazar Jr., G.1
  • 25
    • 5444254615 scopus 로고    scopus 로고
    • Basophils initiate IL-4 production during a memory T-dependent response
    • Khodoun, M.V., Orekhova, T., Potter, C., Morris, S., and Finkelman, F.D. 2004. Basophils initiate IL-4 production during a memory T-dependent response. J. Exp. Med. 200:857-870.
    • (2004) J. Exp. Med. , vol.200 , pp. 857-870
    • Khodoun, M.V.1    Orekhova, T.2    Potter, C.3    Morris, S.4    Finkelman, F.D.5
  • 26
    • 0033577901 scopus 로고    scopus 로고
    • Modulation of immunoglobulin (Ig)E-mediated systemic anaphylaxis by low-affinity Fc receptors for IgG
    • Ujike, A., et al. 1999. Modulation of immunoglobulin (Ig)E-mediated systemic anaphylaxis by low-affinity Fc receptors for IgG. J. Exp. Med. 189:1573-1579.
    • (1999) J. Exp. Med. , vol.189 , pp. 1573-1579
    • Ujike, A.1
  • 27
    • 0030031886 scopus 로고    scopus 로고
    • Augmented humoral and anaphylactic responses in FcγRII-deficient mice
    • Takai, T., Ono, M., Hikida, M., Ohmori, H., and Ravetch, J.V. 1996. Augmented humoral and anaphylactic responses in FcγRII-deficient mice. Nature. 379:346-349.
    • (1996) Nature , vol.379 , pp. 346-349
    • Takai, T.1    Ono, M.2    Hikida, M.3    Ohmori, H.4    Ravetch, J.V.5
  • 28
    • 4344605211 scopus 로고    scopus 로고
    • Inhibition of allergen-specific IgE reactivity by a human Ig Fcγ-Fcε bifunctional fusion protein
    • Zhang, K., et al. 2004. Inhibition of allergen-specific IgE reactivity by a human Ig Fcγ-Fcε bifunctional fusion protein. J. Allergy Clin. Immunol. 114:321-327.
    • (2004) J. Allergy Clin. Immunol. , vol.114 , pp. 321-327
    • Zhang, K.1
  • 29
    • 9644266790 scopus 로고    scopus 로고
    • Genetically engineered negative signaling molecules in the immunomodulation of allergic diseases
    • Saxon, A., Zhu, D., Zhang, K., Allen, L.C., and Kepley, C.L. 2004. Genetically engineered negative signaling molecules in the immunomodulation of allergic diseases. Curr. Opin. Allergy Clin. Immunol. 4:563-568.
    • (2004) Curr. Opin. Allergy Clin. Immunol. , vol.4 , pp. 563-568
    • Saxon, A.1    Zhu, D.2    Zhang, K.3    Allen, L.C.4    Kepley, C.L.5
  • 30
    • 2442679050 scopus 로고    scopus 로고
    • A promoter haplotype of the immunoreceptor tyrosine-based inhibitory motif-bearing FcγRIIb alters receptor expression and associates with autoimmunity. II. Differential binding of GATA4 and Yin-Yang1 transcription factors and correlated receptor expression and function
    • Su, K., et al. 2004. A promoter haplotype of the immunoreceptor tyrosine-based inhibitory motif-bearing FcγRIIb alters receptor expression and associates with autoimmunity. II. Differential binding of GATA4 and Yin-Yang1 transcription factors and correlated receptor expression and function. J. Immunol. 172:7192-7199.
    • (2004) J. Immunol. , vol.172 , pp. 7192-7199
    • Su, K.1
  • 31
    • 0242579484 scopus 로고    scopus 로고
    • A novel polymorphism in the FcγRIIB (CD32B) transmembrane region alters receptor signaling
    • Li, X., et al. 2003. A novel polymorphism in the FcγRIIB (CD32B) transmembrane region alters receptor signaling. Arthritis Rheum. 48:3242-3252.
    • (2003) Arthritis Rheum. , vol.48 , pp. 3242-3252
    • Li, X.1
  • 33
    • 14844293584 scopus 로고    scopus 로고
    • Pathogenesis and management of anaphylaxis: Current status and future challenges
    • Galli, S.J. 2005. Pathogenesis and management of anaphylaxis: current status and future challenges. J. Allergy Clin. Immunol. 115:571-574.
    • (2005) J. Allergy Clin. Immunol. , vol.115 , pp. 571-574
    • Galli, S.J.1
  • 34
    • 14844337103 scopus 로고    scopus 로고
    • Targeting the IgE molecule in allergic and asthmatic diseases: Review of the IgE molecule and clinical efficacy
    • Poole, J.A., Matangkasombut, P., and Rosenwasser, L.J. 2005. Targeting the IgE molecule in allergic and asthmatic diseases: review of the IgE molecule and clinical efficacy [review]. J. Allergy Clin. Immunol. 115(Suppl. 3):S376-S385.
    • (2005) J. Allergy Clin. Immunol. , vol.115 , Issue.3 SUPPL.
    • Poole, J.A.1    Matangkasombut, P.2    Rosenwasser, L.J.3
  • 35
    • 17644388057 scopus 로고    scopus 로고
    • A chimeric human-cat fusion protein blocks cat-induced allergy
    • Zhu, D., et al. 2005. A chimeric human-cat fusion protein blocks cat-induced allergy. Nat. Med. 11:446-449.
    • (2005) Nat. Med. , vol.11 , pp. 446-449
    • Zhu, D.1
  • 36
    • 0036513314 scopus 로고    scopus 로고
    • The potential of peptide immunotherapy in allergy and asthma
    • Ali, F.R., Kay, A.B., and Larche, M. 2002. The potential of peptide immunotherapy in allergy and asthma. Curr. Allergy Asthma Rep. 2:151-158.
    • (2002) Curr. Allergy Asthma Rep. , vol.2 , pp. 151-158
    • Ali, F.R.1    Kay, A.B.2    Larche, M.3
  • 37
    • 0037395291 scopus 로고    scopus 로고
    • Allergen-specific T-cell tolerance induction with allergen-derived long synthetic peptides: Results of a phase I trial
    • Fellrath, J.M., et al. 2003. Allergen-specific T-cell tolerance induction with allergen-derived long synthetic peptides: results of a phase I trial. J. Allergy Clin. Immunol. 111:854-861.
    • (2003) J. Allergy Clin. Immunol. , vol.111 , pp. 854-861
    • Fellrath, J.M.1
  • 38
    • 0020504592 scopus 로고
    • Antibodies to purified bee venom proteins and peptides. II. A detailed study of changes in IgE and IgG antibodies to individual bee venom antigens
    • Kemeny, D.M., MacKenzie-Mills, M., Harries, M.G., Youlten, L.J., and Lessof, M.H. 1983. Antibodies to purified bee venom proteins and peptides. II. A detailed study of changes in IgE and IgG antibodies to individual bee venom antigens. J. Allergy Clin. Immunol. 72:376-385.
    • (1983) J. Allergy Clin. Immunol. , vol.72 , pp. 376-385
    • Kemeny, D.M.1    MacKenzie-Mills, M.2    Harries, M.G.3    Youlten, L.J.4    Lessof, M.H.5
  • 39
    • 0037210385 scopus 로고    scopus 로고
    • Vaccination for birch pollen allergy. Induction of affinity-matured or blocking IgG antibodies does not account for the reduced binding of IgE to Bet v 1
    • Svenson, M., et al. 2003. Vaccination for birch pollen allergy. Induction of affinity-matured or blocking IgG antibodies does not account for the reduced binding of IgE to Bet v 1. Mol. Immunol. 39:603-612.
    • (2003) Mol. Immunol. , vol.39 , pp. 603-612
    • Svenson, M.1
  • 40
    • 2942557008 scopus 로고    scopus 로고
    • Allergen rush immunotherapy increases interleukin (IL)-12 production and IL-12Rβ2 chain expression in patients with allergic asthma
    • Tazaki, T., et al. 2004. Allergen rush immunotherapy increases interleukin (IL)-12 production and IL-12Rβ2 chain expression in patients with allergic asthma. Cell. Immunol. 228:20-26.
    • (2004) Cell. Immunol. , vol.228 , pp. 20-26
    • Tazaki, T.1
  • 41
    • 0037833502 scopus 로고    scopus 로고
    • Immunomodulation during sublingual therapy in allergic children
    • Ippoliti, F., et al. 2003. Immunomodulation during sublingual therapy in allergic children. Pediatr. Allergy Immunol. 14:216-221.
    • (2003) Pediatr. Allergy Immunol. , vol.14 , pp. 216-221
    • Ippoliti, F.1
  • 42
    • 0036164580 scopus 로고    scopus 로고
    • Grass pollen immunotherapy for hayfever is associated with increases in local nasal but not peripheral Th1:Th2 cytokine ratios
    • Wachholz, P.A., et al. 2002. Grass pollen immunotherapy for hayfever is associated with increases in local nasal but not peripheral Th1:Th2 cytokine ratios. Immunology. 105:56-62.
    • (2002) Immunology , vol.105 , pp. 56-62
    • Wachholz, P.A.1
  • 43
    • 0018096538 scopus 로고
    • Decrease of mast cells in W/Wv mice and their increase by bone marrow transplantation
    • Kitamura, Y., Go, S., and Hatanaka, K. 1978. Decrease of mast cells in W/Wv mice and their increase by bone marrow transplantation. Blood. 52:447-452.
    • (1978) Blood , vol.52 , pp. 447-452
    • Kitamura, Y.1    Go, S.2    Hatanaka, K.3
  • 44
    • 0028071646 scopus 로고
    • Active anaphylaxis in IgE-deficient mice
    • Oettgen, H.C., et al. 1994. Active anaphylaxis in IgE-deficient mice. Nature. 370:367-370.
    • (1994) Nature , vol.370 , pp. 367-370
    • Oettgen, H.C.1
  • 45
    • 0019942891 scopus 로고
    • Polyclonal activation of the murine immune system by an antibody to IgD. I. Increase in cell size and DNA synthesis
    • Finkelman, F.D., Scher, I., Mond, J.J., Kung, J.T., and Metcalf, E.S. 1982. Polyclonal activation of the murine immune system by an antibody to IgD. I. Increase in cell size and DNA synthesis. J. Immunol. 129:629-637.
    • (1982) J. Immunol. , vol.129 , pp. 629-637
    • Finkelman, F.D.1    Scher, I.2    Mond, J.J.3    Kung, J.T.4    Metcalf, E.S.5
  • 46
    • 0018291288 scopus 로고
    • Characterization of a monoclonal antibody directed against mouse macrophage and lymphocyte Fc receptors
    • Unkeless, J.C. 1979. Characterization of a monoclonal antibody directed against mouse macrophage and lymphocyte Fc receptors. J. Exp. Med. 150:580-596.
    • (1979) J. Exp. Med. , vol.150 , pp. 580-596
    • Unkeless, J.C.1
  • 47
    • 0021175924 scopus 로고
    • Inhibition of IgE binding to mast cells and basophils by monoclonal antibodies to murine IgE
    • Baniyash, M., and Eshhar, Z. 1984. Inhibition of IgE binding to mast cells and basophils by monoclonal antibodies to murine IgE. Eur. J. Immunol. 14:799-807.
    • (1984) Eur. J. Immunol. , vol.14 , pp. 799-807
    • Baniyash, M.1    Eshhar, Z.2
  • 48
    • 0019452362 scopus 로고
    • Thirteen hybridomas secreting hapten-specific immunoglobulin E from mice with Iga or Igb heavy chain haplotype
    • Rudolph, A.K., Burrows, P.D., and Wabl, M.R. 1981. Thirteen hybridomas secreting hapten-specific immunoglobulin E from mice with Iga or Igb heavy chain haplotype. Eur. J. Immunol. 11:527-529.
    • (1981) Eur. J. Immunol. , vol.11 , pp. 527-529
    • Rudolph, A.K.1    Burrows, P.D.2    Wabl, M.R.3
  • 49
    • 0019509127 scopus 로고
    • IgD-secreting murine plasmacytomas: Identification and partial characterization of two IgD myeloma proteins
    • Finkelman, F.D., Kessler, S.W., Mushinski, J.F., and Potter, M. 1981. IgD-secreting murine plasmacytomas: identification and partial characterization of two IgD myeloma proteins. J. Immunol. 126:680-687.
    • (1981) J. Immunol. , vol.126 , pp. 680-687
    • Finkelman, F.D.1    Kessler, S.W.2    Mushinski, J.F.3    Potter, M.4
  • 50
    • 0027239843 scopus 로고
    • Anti-cytokine antibodies as carrier proteins. Prolongation of in vivo effects of exogenous cytokines by injection of cytokine-anti-cytokine antibody complexes
    • Finkelman, F.D., et al. 1993. Anti-cytokine antibodies as carrier proteins. Prolongation of in vivo effects of exogenous cytokines by injection of cytokine-anti-cytokine antibody complexes. J. Immunol. 151:1235-1244.
    • (1993) J. Immunol. , vol.151 , pp. 1235-1244
    • Finkelman, F.D.1
  • 51
    • 0032738991 scopus 로고    scopus 로고
    • Development of an assay to measure in vivo cytokine production in the mouse
    • Finkelman, F.D., and Morris, S.C. 1999. Development of an assay to measure in vivo cytokine production in the mouse. Int. Immunol. 11:1811-1818.
    • (1999) Int. Immunol. , vol.11 , pp. 1811-1818
    • Finkelman, F.D.1    Morris, S.C.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.