Stepwise in vitro affinity maturation of Vitaxin, an αvβ3-specific humanized mAb

Proceedings of the National Academy of Sciences of the United States of America

Volumn 95, Issue 11, 1998, Pages 6037-6042

  Wu, Herren ^a   Beuerlein, Gregory ^a   Nie, Ying ^a   Smith, Heidi ^a   Lee, Bruce A ^a,b   Hensler, Mary ^a   Huse, William D ^a   Watkins, Jeffry D ^a  

^a Ixsys Inc   (United States)

^b Biosite Incorporated   (United States)

Author keywords

Angiogenesis; Antibody engineering; Capture lift; Codon based mutagenesis; Phage expression

Indexed keywords

FIBRINOGEN; FIBRINOGEN RECEPTOR; MONOCLONAL ANTIBODY; MONOCLONAL ANTIBODY LM 609; UNCLASSIFIED DRUG; VITRONECTIN;

ANTIGEN BINDING; ARTICLE; CELL ADHESION; COMPLEMENTARITY DETERMINING REGION; HUMAN; HUMAN CELL; LIGAND BINDING; MELANOMA CELL; MUTAGENESIS; PRIORITY JOURNAL;

MAMMALIA;

EID: 0032568558     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.95.11.6037     Document Type: Article

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