Mapping of conformational IgE epitopes with peptide-specific monoclonal antibodies reveals simultaneous binding of different IgE antibodies to a surface patch on the major birch pollen allergen, Bet v 1

Journal of Immunology

Volumn 186, Issue 9, 2011, Pages 5333-5344

  Gieras, Anna ^a   Cejka, Petra ^b   Blatt, Katharina ^a   Focke Tejkl, Margarete ^a   Linhart, Birgit ^a   Flicker, Sabine ^a   Stoecklinger, Angelika ^c   Marth, Katharina ^a   Drescher, Anja ^d   Thalhamer, Josef ^c   Valent, Peter ^a   Majdic, Otto ^b   Valenta, Rudolf ^a  

^a MEDICAL UNIVERSITY OF VIENNA   (Austria)

^b MEDICAL UNIVERSITY OF VIENNA   (Austria)

^c UNIVERSITY OF SALZBURG   (Austria)

^d Biacore/GE Healthcare   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ALLERGEN BET V 1; ASPARAGINYLPHENYLALANYLLYSYLTYROSYLASPARAGINYLTYROSYLSERYLVALYLISOLEUCYLGLUTAMYLGLYCYLGLYCYLPROLYLISOLEUCYLGLYCYLASPARTYLTHREONYLLEUCYLGLUTAMYLLYSYLISOLEUCYLSERYLASPARAGINYLGLUTAMYLISOLEUCYLLYSINE; CYSTYLGLUTAMYLVALYLASPARTYLHISTIDINYLTHREONYLASPARAGINYLPHENYLALANYLLYSYLTYROSYLASPARAGINYLTYROSYLSERYLVALYLISOLEUCYLGLUTAMYLGLYCYLGLYCYLPROLYLISOLEUCYLGLYCYLASPARTYLTHREONYLLEUCYLGLUTAMYLLYSYLISOLEUCYLSERYLASPARAGINYLGLUTAMYLISOLEUCYLLYSINE; CYSTYLGLYCYLPROLYLGLYCYLTYROSYLISOLEUCYLLYSYLLYSYLISOLEUCYLSERYLPHENYLALANYLPROLYLGLUTAMYLGLYCYLPHENYLALANYLLYSYLTYROSYLVALYLLYSYLASPARTYLARGINYLVALYLASPARTYLGLUTAMYLVALYLASPARTYLHISTIDINYLTHREONYLASPARAGINE; GLUTAMYLVALYLASPARTYLHISTIDINYLTHREONYLASPARAGINYLPHENYLALANYLLYSYLTYROSYLASPARAGINYLTYROSYLSERYLVALYLISOLEUCYLGLUTAMYLGLYCINE; GLUTAMYLVALYLASPARTYLHISTIDINYLTHREONYLASPARAGINYLPHENYLALANYLLYSYLTYROSYLASPARAGINYLTYROSYLSERYLVALYLISOLEUCYLGLUTAMYLGLYCYLGLYCYLPROLYLISOLEUCYLGLYCYLASPARTIC ACID; GLUTAMYLVALYLASPARTYLHISTIDINYLTHREONYLASPARAGINYLPHENYLALANYLLYSYLTYROSYLASPARAGINYLTYROSYLSERYLVALYLISOLEUCYLGLUTAMYLGLYCYLGLYCYLPROLYLISOLEUCYLGLYCYLASPARTYLTHREONYLLEUCYLGLUTAMYLLYSYLISOLEUCINE; GLYCYLGLYCYLPROLYLISOLEUCYLGLYCYLASPARTYLTHREONYLLEUCYLGLUTAMYLLYSYLISOLEUCYLSERYLASPARAGINYLGLUTAMYLISOLEUCYLLYSINE; IMMUNOGLOBULIN E ANTIBODY; ISOLEUCYLGLUTAMYLGLYCYLASPARAGINYLGLUTAMYLGLUTAMYLPROLYLGLYCYLTHREONYLISOLEUCYLLYSYLLYSYLISOLEUCYLSERYLPHENYLALANINE; LEUCYLPHENYLALANYLPROLYLLYSYLVALYLALANYLPROLYLGLUTAMINYLALANYLISOLEUCYLSERYLSERYLVALYLGLUTAMYLASPARAGINYLISOLEUCYLGLUTAMYLGLYCYLASPARAGINYLGLUTAMYLGLUTAMYLPROLYLGLYCYLTHREONYLISOLEUCINE; LEUCYLPHENYLALANYLPROLYLLYSYLVALYLALANYLPROLYLGLUTAMINYLALANYLISOLEUCYLSERYLSERYLVALYLGLUTAMYLASPARAGINYLISOLEUCYLGLUTAMYLGLYCYLASPARAGINYLGLUTAMYLGLUTAMYLPROLYLGLYCYLTHREONYLISOLEUCYLLYSYLLYSYLISOLEUCYLSERYLPHENYLALANYLCYSTEINE; MONOCLONAL ANTIBODY; POLLEN ANTIGEN; POLYCLONAL ANTIBODY; SERYLSERYLVALYLGLUTAMYLASPARAGINYLISOLEUCYLGLUTAMYLGLYCYLASPARAGINYLGLUTAMYLGLUTAMYLPROLYLGLYCYLTHREONYLISOLEUCYLLYSYLLYSYLISOLEUCYLSERYLPHENYLALANINE; SYNTHETIC PEPTIDE; TYROSYLASPARAGINYLTYROSYLSERYLVALYLISOLEUCYLGLUTAMYLGLYCYLGLYCYLPROLYLISOLEUCYLGLYCYLASPARTYLTHREONYLLEUCYLGLUTAMYLLYSYLISOLEUCYLSERYLASPARAGINYLGLUTAMYLISOLEUCYLLYSINE; UNCLASSIFIED DRUG; VALYLALANYLPROLYLGLUTAMINYLALANYLISOLEUCYLSERYLSERYLVALYLGLUTAMYLASPARAGINYLISOLEUCYLGLUTAMYLGLYCYLASPARAGINYLGLUTAMYLGLUTAMYLPROLYLGLYCYLTHREONYLISOLEUCYLLYSYLLYSYLISOLEUCYLSERYLPHENYLALANINE;

ALLERGENICITY; ALLERGIC REACTION; AMINO ACID SEQUENCE; ANIMAL EXPERIMENT; ANTIBODY AFFINITY; ANTIBODY SPECIFICITY; ANTIGEN ANTIBODY COMPLEX; ANTIGEN BINDING; ANTIGEN RECOGNITION; ARTICLE; BASOPHIL DEGRANULATION; BINDING SITE; BIRCH; CLINICAL ARTICLE; CONCENTRATION RESPONSE; CONFORMATIONAL TRANSITION; CONTROLLED STUDY; DRUG TARGETING; EPITOPE MAPPING; HUMAN; HUMAN CELL; MAST CELL DEGRANULATION; MOUSE; NONHUMAN; POLLEN ALLERGY; PRIORITY JOURNAL; SURFACE PLASMON RESONANCE;

AMINO ACID SEQUENCE; ANIMALS; ANTIBODIES, MONOCLONAL; ANTIBODY SPECIFICITY; ANTIGENS, PLANT; BASOPHILS; BETULA; BINDING, COMPETITIVE; CROSS REACTIONS; ENZYME-LINKED IMMUNOSORBENT ASSAY; EPITOPE MAPPING; EPITOPES, B-LYMPHOCYTE; HUMANS; HYPERSENSITIVITY; IMMUNOGLOBULIN E; MICE; MICE, INBRED BALB C; MOLECULAR SEQUENCE DATA; PEPTIDES; POLLEN; RABBITS; SEQUENCE HOMOLOGY, AMINO ACID;

EID: 79955549894     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.1000804     Document Type: Article

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