Modifications to an Fcγ-Fcε fusion protein alter its effectiveness in the inhibition of FcεRI-mediated functions

Journal of Allergy and Clinical Immunology

Volumn 120, Issue 2, 2007, Pages 462-468

  Allen, Lisa Chan ^a   Kepley, Christopher L ^b   Saxon, Andrew ^a   Zhang, Ke ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b Massey Cancer Center   (United States)

Author keywords

allergy; Fc RIIb; Fc RI; GE2; IgE; IgG

Indexed keywords

FC EPSILON RECEPTOR 1; FC GAMMA RECEPTOR 2B; FC GAMMA RECEPTOR 3; FC RECEPTOR; HYBRID PROTEIN; IMMUNOGLOBULIN E; IMMUNOGLOBULIN RECEPTOR; MUTANT PROTEIN; PROTEIN E2G; PROTEIN GE H; PROTEIN GE S; PROTEIN GE2; UNCLASSIFIED DRUG; FCGR2B PROTEIN, HUMAN; IMMUNOGLOBULIN E RECEPTOR; ISOPROTEIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BASOPHIL; BASOPHIL DEGRANULATION; CONTROLLED STUDY; HISTAMINE RELEASE; HUMAN; HUMAN CELL; MOUSE; NONHUMAN; PASSIVE SKIN ANAPHYLAXIS; PRIORITY JOURNAL; PROTEIN MODIFICATION; RECEPTOR BINDING; ANIMAL; CELL LINE; CHEMISTRY; DEGRANULATION; DRUG ANTAGONISM; DRUG EFFECT; GENETICS; METABOLISM; MUTATION; PHYSIOLOGY; TRANSGENIC MOUSE;

ANIMALS; BASOPHILS; CELL DEGRANULATION; CELL LINE; HUMANS; MICE; MICE, TRANSGENIC; MUTATION; PASSIVE CUTANEOUS ANAPHYLAXIS; PROTEIN ISOFORMS; RECEPTORS, IGE; RECEPTORS, IGG; RECOMBINANT FUSION PROTEINS;

EID: 34547101712     PISSN: 00916749     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jaci.2007.04.019     Document Type: Article

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