-
1
-
-
0035252592
-
E2Fs regulate the expression of genes involved in differentiation, development, proliferation and apoptosis
-
PMID:11159908; DOI:10.1101/gad.864201
-
Müller H, Bracken AP, Vernell R, Moroni MC, Christians F, Grassilli E, et al. E2Fs regulate the expression of genes involved in differentiation, development, proliferation and apoptosis. Genes Dev 2001; 15:267-85; PMID:11159908; DOI:10.1101/gad.864201.
-
(2001)
Genes Dev
, vol.15
, pp. 267-285
-
-
Müller, H.1
Bracken, A.P.2
Vernell, R.3
Moroni, M.C.4
Christians, F.5
Grassilli, E.6
-
2
-
-
0034949169
-
Role for E2F in the control of both DNA replication and mitotic functions as revealed from DNA microarray analysis
-
PMID:11416145; DOI:10.1128/MCB.21.14.4684-99.2001
-
Ishida S, Huang E, Zuzan H, Spang R, Leone G, West M, et al. Role for E2F in the control of both DNA replication and mitotic functions as revealed from DNA microarray analysis. Mol Cell Biol 2001; 21:4684-99; PMID:11416145; DOI:10.1128/MCB.21.14.4684-99.2001.
-
(2001)
Mol Cell Biol
, vol.21
, pp. 4684-4699
-
-
Ishida, S.1
Huang, E.2
Zuzan, H.3
Spang, R.4
Leone, G.5
West, M.6
-
3
-
-
50149108858
-
Conserved functions of the pRB and E2F families
-
PMID:18719710; DOI:10.1038/nrm2469
-
van den Heuvel S, Dyson N. Conserved functions of the pRB and E2F families. Nat Rev Mol Cell Biol 2008; 9:713-24; PMID:18719710; DOI:10.1038/nrm2469.
-
(2008)
Nat Rev Mol Cell Biol
, vol.9
, pp. 713-724
-
-
Van Den Heuvel, S.1
Dyson, N.2
-
4
-
-
0034737290
-
1and S phase of the cell cycle is regulated by repressor complexes containing HDAC-Rb-hSWI/SNF and Rb-hSWI/SNF
-
PMID:10778858; DOI:10.1016/S0092-8674(00)80625-X
-
1 and S phase of the cell cycle is regulated by repressor complexes containing HDAC-Rb-hSWI/SNF and Rb-hSWI/SNF. Cell 2000; 101:79-89; PMID:10778858; DOI:10.1016/S0092-8674(00)80625-X.
-
(2000)
Cell
, vol.101
, pp. 79-89
-
-
Zhang, H.S.1
Gavin, M.2
Dahiya, A.3
Postigo, A.A.4
Ma, D.5
Luo, R.X.6
-
5
-
-
0028222124
-
p53 and E2F-1 cooperate to mediate apoptosis
-
PMID:8170954; DOI:10.1073/pnas.91.9.3602
-
Wu X, Levine AJ. p53 and E2F-1 cooperate to mediate apoptosis. Proc Natl Acad Sci USA 1994; 91:3602-6; PMID:8170954; DOI:10.1073/pnas.91.9.3602.
-
(1994)
Proc Natl Acad Sci USA
, vol.91
, pp. 3602-3606
-
-
Wu, X.1
Levine, A.J.2
-
6
-
-
0028169994
-
p53-dependent apoptosis suppresses tumor growth progress in vivo
-
PMID:8069917; DOI:10.1016/0092-8674(94)90534-7
-
Symonds H, Krall L, Remington L, Saenz-Robles M, Lowe S, Jacks T, et al. p53-dependent apoptosis suppresses tumor growth progress in vivo. Cell 1994; 78:703-11; PMID:8069917; DOI:10.1016/0092-8674(94)90534-7.
-
(1994)
Cell
, vol.78
, pp. 703-711
-
-
Symonds, H.1
Krall, L.2
Remington, L.3
Saenz-Robles, M.4
Lowe, S.5
Jacks, T.6
-
8
-
-
0141814666
-
Specificity in the activation and control of transcription factor E2Fdependent apoptosis
-
PMID:12954980; DOI:10.1073/pnas.1831408100
-
Hallstrom TC, Nevins JR. Specificity in the activation and control of transcription factor E2Fdependent apoptosis. Proc Natl Acad Sci USA 2003; 100:10848-53; PMID:12954980; DOI:10.1073/pnas.1831408100.
-
(2003)
Proc Natl Acad Sci USA
, vol.100
, pp. 10848-10853
-
-
Hallstrom, T.C.1
Nevins, J.R.2
-
9
-
-
37349070024
-
An E2F1-dependent gene expression program that determines the balance between proliferation and cell death
-
PMID:18167336; DOI:10.1016/j.ccr.2007.11.031
-
Hallstrom TC, Mori S, Nevins JR. An E2F1-dependent gene expression program that determines the balance between proliferation and cell death. Cancer Cell 2008; 13:11-22; PMID:18167336; DOI:10.1016/j.ccr.2007.11.031.
-
(2008)
Cancer Cell
, vol.13
, pp. 11-22
-
-
Hallstrom, T.C.1
Mori, S.2
Nevins, J.R.3
-
10
-
-
11144358645
-
High frequency of mutations of the PIK3CA gene in human cancers
-
PMID:15016963; DOI:10.1126/science.1096502
-
Samuels Y, Wang Z, Bardelli A, Silliman N, Ptak J, Szabo S, et al. High frequency of mutations of the PIK3CA gene in human cancers. Science 2004; 304:554; PMID:15016963; DOI:10.1126/science.1096502.
-
(2004)
Science
, vol.304
, pp. 554
-
-
Samuels, Y.1
Wang, Z.2
Bardelli, A.3
Silliman, N.4
Ptak, J.5
Szabo, S.6
-
11
-
-
33644776551
-
Jab1 is a specificity factor for E2F1-induced apoptosis
-
PMID:16481464; DOI:10.1101/gad.1345006
-
Hallstrom TC, Nevins JR. Jab1 is a specificity factor for E2F1-induced apoptosis. Genes Dev 2006; 20:613-23; PMID:16481464; DOI:10.1101/gad.1345006.
-
(2006)
Genes Dev
, vol.20
, pp. 613-623
-
-
Hallstrom, T.C.1
Nevins, J.R.2
-
12
-
-
0029761277
-
A new group of conserved coactivators that increase the specificity of Ap-1 transcription factors
-
PMID:8837781; DOI:10.1038/383453a0
-
Claret FX, Hibi M, Dhut S, Toda T, Karin M. A new group of conserved coactivators that increase the specificity of Ap-1 transcription factors. Nature 1996; 383:453-7; PMID:8837781; DOI:10.1038/383453a0.
-
(1996)
Nature
, vol.383
, pp. 453-457
-
-
Claret, F.X.1
Hibi, M.2
Dhut, S.3
Toda, T.4
Karin, M.5
-
13
-
-
0028365625
-
Arabidopsis COP9 is a component of a novel signaling complex mediating light control of development
-
PMID:8033203; DOI:10.1016/0092-8674(94)90578-9
-
Wei N, Chamovitz DA, Deng XW. Arabidopsis COP9 is a component of a novel signaling complex mediating light control of development. Cell 1994; 78:117-24; PMID:8033203; DOI:10.1016/0092-8674(94)90578-9.
-
(1994)
Cell
, vol.78
, pp. 117-124
-
-
Wei, N.1
Chamovitz, D.A.2
Deng, X.W.3
-
14
-
-
0030581153
-
The COP9 complex, a novel multisubunit nuclear regulator involved in light control of a plant developmental switch
-
PMID:8689678; DOI:10.1016/S0092-8674(00)80082-3
-
Chamovitz DA, Wei N, Osterlund MT, Von Arnim AG, Staub JM, Matsui M, et al. The COP9 complex, a novel multisubunit nuclear regulator involved in light control of a plant developmental switch. Cell 1996; 86:115-21; PMID:8689678; DOI:10.1016/S0092-8674(00)80082-3.
-
(1996)
Cell
, vol.86
, pp. 115-121
-
-
Chamovitz, D.A.1
Wei, N.2
Osterlund, M.T.3
Von Arnim, A.G.4
Staub, J.M.5
Matsui, M.6
-
15
-
-
0032203713
-
Arabidopsis homologs of a c-Jun coactivator are present both in monomeric form and in the COP9 complex, and their abundance is differentially affected by the pleiotropic cop/det/fus mutations
-
PMID:9811788
-
Kwok SF, Solano R, Tsuge T, Chamovitz DA, Ecker JR, Matsui M, et al. Arabidopsis homologs of a c-Jun coactivator are present both in monomeric form and in the COP9 complex, and their abundance is differentially affected by the pleiotropic cop/det/fus mutations. Plant Cell 1998; 10:1779-90; PMID:9811788.
-
(1998)
Plant Cell
, vol.10
, pp. 1779-1790
-
-
Kwok, S.F.1
Solano, R.2
Tsuge, T.3
Chamovitz, D.A.4
Ecker, J.R.5
Matsui, M.6
-
16
-
-
13844259319
-
Small Jab1-containing subcomplex is regulated in an anchorage- and cell cycle-dependent manner, which is abrogated by ras transformation
-
PMID:15710389; DOI:10.1016/j.febslet.2004.12.076
-
Fukumoto A, Tomoda K, Kubota M, Kato JY, Yoneda-Kato N. Small Jab1-containing subcomplex is regulated in an anchorage- and cell cycle-dependent manner, which is abrogated by ras transformation. FEBS Lett 2005; 579:1047-54; PMID:15710389; DOI:10.1016/j.febslet.2004.12.076.
-
(2005)
FEBS Lett
, vol.579
, pp. 1047-1054
-
-
Fukumoto, A.1
Tomoda, K.2
Kubota, M.3
Kato, J.Y.4
Yoneda-Kato, N.5
-
17
-
-
56449094567
-
The COP9 signalosome: More than a protease
-
PMID:18926707; DOI:10.1016/j.tibs.2008.09.004
-
Wei N, Serino G, Deng XW. The COP9 signalosome: more than a protease. Trends Biochem Sci 2008; 33:592-600; PMID:18926707; DOI:10.1016/j.tibs.2008.09. 004.
-
(2008)
Trends Biochem Sci
, vol.33
, pp. 592-600
-
-
Wei, N.1
Serino, G.2
Deng, X.W.3
-
18
-
-
77957914630
-
JAB1/CSN5: A new player in cell cycle control and cancer
-
PMID:20955608; DOI:10.1186/1747-1028-5-26
-
Shackleford TJ, Claret FX. JAB1/CSN5: a new player in cell cycle control and cancer. Cell Div 2010; 5:26; PMID:20955608; DOI:10.1186/1747-1028-5-26.
-
(2010)
Cell Div
, vol.5
, pp. 26
-
-
Shackleford, T.J.1
Claret, F.X.2
-
19
-
-
33644503868
-
Identification of pathways regulating cell size and cell cycle progression by RNAi
-
PMID:16496002; DOI:10.1038/nature04469
-
Björklund M, Taipale M, Varjosalo M, Saharinen J, Lahdenperä J, Taipale J. Identification of pathways regulating cell size and cell cycle progression by RNAi. Nature 2006; 439:1009-13; PMID:16496002; DOI:10.1038/nature04469.
-
(2006)
Nature
, vol.439
, pp. 1009-1013
-
-
Björklund, M.1
Taipale, M.2
Varjosalo, M.3
Saharinen, J.4
Lahdenperä, J.5
Taipale, J.6
-
20
-
-
38849098442
-
Cancer proliferation gene discovery through functional genomics
-
PMID:18239126; DOI:10.1126/science.1149200
-
Schlabach MR, Luo J, Solimini NL, Hu G, Xu Q, Li MZ, et al. Cancer proliferation gene discovery through functional genomics. Science 2008; 319:620-4; PMID:18239126; DOI:10.1126/science.1149200.
-
(2008)
Science
, vol.319
, pp. 620-624
-
-
Schlabach, M.R.1
Luo, J.2
Solimini, N.L.3
Hu, G.4
Xu, Q.5
Li, M.Z.6
-
21
-
-
0033545636
-
Kip1 is instigated by Jab1
-
PMID:10086358; DOI:10.1038/18230
-
Kip1 is instigated by Jab1. Nature 1999; 398:160-5; PMID:10086358; DOI:10.1038/18230.
-
(1999)
Nature
, vol.398
, pp. 160-165
-
-
Tomoda, K.1
Kubota, Y.2
Kato, J.3
-
22
-
-
0037567489
-
Jun activation domain-binding protein 1 expression in breast cancer inversely correlates with the cell cycle inhibitor p27(Kip1)
-
PMID:12782606
-
Kouvaraki MA, Rassidakis GZ, Tian L, Kumar R, Kittas C, Claret FX. Jun activation domain-binding protein 1 expression in breast cancer inversely correlates with the cell cycle inhibitor p27(Kip1). Cancer Res 2003; 63:2977-81; PMID:12782606.
-
(2003)
Cancer Res
, vol.63
, pp. 2977-2981
-
-
Kouvaraki, M.A.1
Rassidakis, G.Z.2
Tian, L.3
Kumar, R.4
Kittas, C.5
Claret, F.X.6
-
23
-
-
0344629812
-
Jun activation domain binding protein 1 expression is associated with low p27(Kip1) levels in node-negative breast cancer
-
PMID:14654548
-
Esteva FJ, Sahin AA, Rassidakis GZ, Yuan LX, Smith TL, Yang Y, et al. Jun activation domain binding protein 1 expression is associated with low p27(Kip1) levels in node-negative breast cancer. Clin Cancer Res 2003; 9:5652-9; PMID:14654548.
-
(2003)
Clin Cancer Res
, vol.9
, pp. 5652-5659
-
-
Esteva, F.J.1
Sahin, A.A.2
Rassidakis, G.Z.3
Yuan, L.X.4
Smith, T.L.5
Yang, Y.6
-
24
-
-
31144459985
-
Oncogenic pathway signatures in human cancers as a guide to targeted therapies
-
PMID:16273092; DOI:10.1038/nature04296
-
Bild AH, Yao G, Chang JT, Wang Q, Potti A, Chasse D, et al. Oncogenic pathway signatures in human cancers as a guide to targeted therapies. Nature 2006; 439:353-7; PMID:16273092; DOI:10.1038/nature04296.
-
(2006)
Nature
, vol.439
, pp. 353-357
-
-
Bild, A.H.1
Yao, G.2
Chang, J.T.3
Wang, Q.4
Potti, A.5
Chasse, D.6
-
25
-
-
0344441259
-
Distinct recruitment of E2F family members to specific E2F-binding sites mediates activation and repression of the E2F1 promoter
-
PMID:14576826; DOI:10.1038/sj.onc.1206840
-
Araki K, Nakajima Y, Eto K, Ikeda MA. Distinct recruitment of E2F family members to specific E2F-binding sites mediates activation and repression of the E2F1 promoter. Oncogene 2003; 22:7632-41; PMID:14576826; DOI:10.1038/sj.onc. 1206840.
-
(2003)
Oncogene
, vol.22
, pp. 7632-7641
-
-
Araki, K.1
Nakajima, Y.2
Eto, K.3
Ikeda, M.A.4
-
26
-
-
0038246295
-
Identification of the e box factor TFE3 as a functional partner for the E2F3 transcription factor
-
PMID:12748276; DOI:10.1128/MCB.23.11.3707-20.2003
-
Giangrande PH, Hallstrom TC, Tunyaplin C, Calame K, Nevins JR. Identification of the E box factor TFE3 as a functional partner for the E2F3 transcription factor. Mol Cell Biol 2003; 23:3707-20; PMID:12748276; DOI:10.1128/MCB.23.11.3707-20.2003.
-
(2003)
Mol Cell Biol
, vol.23
, pp. 3707-3720
-
-
Giangrande, P.H.1
Hallstrom, T.C.2
Tunyaplin, C.3
Calame, K.4
Nevins, J.R.5
-
27
-
-
0036846197
-
Interaction of YY1 with E2Fs, mediated by RYBP, provides a mechanism for specificity of E2F function
-
PMID:12411495; DOI:10.1093/emboj/cdf577
-
Schlisio S, Halperin T, Vidal M, Nevins JR. Interaction of YY1 with E2Fs, mediated by RYBP, provides a mechanism for specificity of E2F function. EMBO J 2002; 21:5775-86; PMID:12411495; DOI:10.1093/emboj/cdf577.
-
(2002)
EMBO J
, vol.21
, pp. 5775-5786
-
-
Schlisio, S.1
Halperin, T.2
Vidal, M.3
Nevins, J.R.4
-
28
-
-
10044254753
-
2/M
-
PMID:15510213; DOI:10.1038/sj.emboj.7600459
-
2/M. EMBO J 2004; 23:4615-26; PMID:15510213; DOI:10.1038/sj.emboj.7600459.
-
(2004)
EMBO J
, vol.23
, pp. 4615-4626
-
-
Zhu, W.1
Giangrande, P.2
Nevins, J.R.3
-
29
-
-
0035794541
-
COP9 signalosomespecific phosphorylation targets p53 to degradation by the ubiquitin system
-
PMID:11285227; DOI:10.1093/emboj/20.7.1630
-
Bech-Otschir D, Kraft R, Huang X, Henklein P, Kapelari B, Pollmann C, et al. COP9 signalosomespecific phosphorylation targets p53 to degradation by the ubiquitin system. EMBO J 2001; 20:1630-9; PMID:11285227; DOI:10.1093/emboj/20.7. 1630.
-
(2001)
EMBO J
, vol.20
, pp. 1630-1639
-
-
Bech-Otschir, D.1
Kraft, R.2
Huang, X.3
Henklein, P.4
Kapelari, B.5
Pollmann, C.6
-
30
-
-
0037016769
-
Jab1 interacts directly with HIF-1alpha and regulates its stability
-
PMID:11707426; DOI:10.1074/jbc.C100442200
-
Bae MK, Ahn MY, Jeong JW, Bae MH, Lee YM, Bae SK, et al. Jab1 interacts directly with HIF-1alpha and regulates its stability. J Biol Chem 2002; 277:9-12; PMID:11707426; DOI:10.1074/jbc.C100442200.
-
(2002)
J Biol Chem
, vol.277
, pp. 9-12
-
-
Bae, M.K.1
Ahn, M.Y.2
Jeong, J.W.3
Bae, M.H.4
Lee, Y.M.5
Bae, S.K.6
-
31
-
-
0036198412
-
Jab1 antagonizes TGFbeta signaling by inducing Smad4 degradation
-
PMID:11818334; DOI:10.1093/embo-reports/kvf024
-
Wan M, Cao X, Wu Y, Bai S, Wu L, Shi X, et al. Jab1 antagonizes TGFbeta signaling by inducing Smad4 degradation. EMBO Rep 2002; 3:171-6; PMID:11818334; DOI:10.1093/embo-reports/kvf024.
-
(2002)
EMBO Rep
, vol.3
, pp. 171-176
-
-
Wan, M.1
Cao, X.2
Wu, Y.3
Bai, S.4
Wu, L.5
Shi, X.6
-
32
-
-
1542314268
-
Jab1/CSN5, a component of the COP9 signalosome, regulates transforming growth factor beta signaling by binding to Smad7 and promoting its degradation
-
PMID:14993265; DOI:10.1128/MCB.24.6.2251-62.2004
-
Kim BC, Lee HJ, Park SH, Lee SR, Karpova TS, McNally JG, et al. Jab1/CSN5, a component of the COP9 signalosome, regulates transforming growth factor beta signaling by binding to Smad7 and promoting its degradation. Mol Cell Biol 2004; 24:2251-62; PMID:14993265; DOI:10.1128/MCB.24.6.2251-62.2004.
-
(2004)
Mol Cell Biol
, vol.24
, pp. 2251-2262
-
-
Kim, B.C.1
Lee, H.J.2
Park, S.H.3
Lee, S.R.4
Karpova, T.S.5
McNally, J.G.6
-
33
-
-
18944391961
-
CSN5/Jab1 is involved in ligand-dependent degradation of estrogen receptor {alpha} by the proteasome
-
PMID:15899841; DOI:10.1128/MCB.25.11.4349-58.2005
-
Calligé M, Kieffer I, Richard-Foy H. CSN5/Jab1 is involved in ligand-dependent degradation of estrogen receptor {alpha} by the proteasome. Mol Cell Biol 2005; 25:4349-58; PMID:15899841; DOI:10.1128/MCB.25.11.4349-58.2005.
-
(2005)
Mol Cell Biol
, vol.25
, pp. 4349-4358
-
-
Calligé, M.1
Kieffer, I.2
Richard-Foy, H.3
-
34
-
-
0034708820
-
JAB1 interacts with both the progesterone receptor and SRC-1
-
PMID:10722692; DOI:10.1074/ jbc.275.12.8540
-
Chauchereau A, Georgiakaki M, Perrin-Wolff M, Milgrom E, Loosfelt H. JAB1 interacts with both the progesterone receptor and SRC-1. J Biol Chem 2000; 275:8540-8; PMID:10722692; DOI:10.1074/ jbc.275.12.8540.
-
(2000)
J Biol Chem
, vol.275
, pp. 8540-8548
-
-
Chauchereau, A.1
Georgiakaki, M.2
Perrin-Wolff, M.3
Milgrom, E.4
Loosfelt, H.5
-
35
-
-
35548940309
-
COP9 signalosome subunit 8 is essential for peripheral T cell homeostasis and antigen receptor-induced entry into the cell cycle from quiescence
-
PMID:17906629; DOI:10.1038/ni1514
-
Menon S, Chi H, Zhang H, Deng XW, Flavell RNW. COP9 signalosome subunit 8 is essential for peripheral T cell homeostasis and antigen receptor-induced entry into the cell cycle from quiescence. Nat Immunol 2007; 8:1236-45; PMID:17906629; DOI:10.1038/ni1514.
-
(2007)
Nat Immunol
, vol.8
, pp. 1236-1245
-
-
Menon, S.1
Chi, H.2
Zhang, H.3
Deng, X.W.4
Flavell, R.N.W.5
-
36
-
-
33751384465
-
A systems approach to interpreting genomic signatures
-
PMID:17000751; DOI:10.1093/bioinformatics/btl483
-
Chang JT, Nevins G Jr. a systems approach to interpreting genomic signatures. Bioinformatics 2006; 22:2926-33; PMID:17000751; DOI:10.1093/ bioinformatics/btl483.
-
(2006)
Bioinformatics
, vol.22
, pp. 2926-2933
-
-
Chang, J.T.1
Nevins Jr., G.2
-
37
-
-
33847661809
-
Protocol for the fast chromatin immunoprecipitation (ChIP) method
-
PMID:17406230; DOI:10.1038/nprot.2006.27
-
Nelson JD, Denisenko O, Bomsztyk K. Protocol for the fast chromatin immunoprecipitation (ChIP) method. Nat Protoc 2006; 1:179-85; PMID:17406230; DOI:10.1038/nprot.2006.27.
-
(2006)
Nat Protoc
, vol.1
, pp. 179-185
-
-
Nelson, J.D.1
Denisenko, O.2
Bomsztyk, K.3
|