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Volumn 81, Issue 1, 2012, Pages 49-54

Generation of bioactive recombinant Ancylostoma caninum anticoagulant peptide c2

Author keywords

Ancylostoma caninum anticoagulant peptide c2; Expression; Gene clone; Intein; Purification

Indexed keywords

ANTICOAGULANT PROTEIN, ANCYLOSTOMA CANINUM; CHITIN; HELMINTH PROTEIN; HYBRID PROTEIN; INTEIN; SERINE PROTEINASE INHIBITOR;

EID: 80053456960     PISSN: 10465928     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.pep.2011.08.029     Document Type: Article
Times cited : (2)

References (30)
  • 1
    • 27644556400 scopus 로고    scopus 로고
    • Clots, kinins and coronaries
    • DOI 10.1016/j.atherosclerosis.2005.05.038, PII S002191500500359X
    • N.L. Cruden, and D.E. Newby Clots, kinins and coronaries Atherosclerosis 183 2005 189 198 (Pubitemid 41579268)
    • (2005) Atherosclerosis , vol.183 , Issue.2 , pp. 189-198
    • Cruden, N.L.M.1    Newby, D.E.2
  • 2
    • 33746854743 scopus 로고    scopus 로고
    • Flow effects on coagulation and thrombosis
    • DOI 10.1161/01.ATV.0000229658.76797.30, PII 0004360520060800000009
    • J.J. Hathcock Flow effects on coagulation and thrombosis Arterioscler. Thromb. Vasc. Biol. 26 2006 1729 1737 (Pubitemid 44305325)
    • (2006) Arteriosclerosis, Thrombosis, and Vascular Biology , vol.26 , Issue.8 , pp. 1729-1737
    • Hathcock, J.J.1
  • 3
    • 33751381292 scopus 로고    scopus 로고
    • Drug Insight: Antithrombotic therapy after percutaneous coronary intervention in patients with an indication for anticoagulation
    • DOI 10.1038/ncpcardio0712, PII NCPCARDIO0712
    • G. Helft, M. Gilard, C. Le Feuvre, and A.G. Zaman Drug insight: antithrombotic therapy after percutaneous coronary intervention in patients with an indication for anticoagulation Nat. Clin. Pract. Cardiovasc. Med. 3 2006 673 680 (Pubitemid 44811527)
    • (2006) Nature Clinical Practice Cardiovascular Medicine , vol.3 , Issue.12 , pp. 673-680
    • Helft, G.1    Gilard, M.2    Le Feuvre, C.3    Zaman, A.G.4
  • 4
    • 0026432629 scopus 로고
    • Oral anticoagulant drugs
    • J. Hirsh Oral anticoagulant drugs N. Engl. J. Med. 324 1991 1865 1875
    • (1991) N. Engl. J. Med. , vol.324 , pp. 1865-1875
    • Hirsh, J.1
  • 5
  • 6
    • 11244337244 scopus 로고    scopus 로고
    • New anticoagulants
    • DOI 10.1182/blood-2003-12-4195
    • J. Hirsh, M. O'Donnell, and J.I. Weitz New anticoagulants Blood 105 2005 453 463 (Pubitemid 40070721)
    • (2005) Blood , vol.105 , Issue.2 , pp. 453-463
    • Hirsh, J.1    O'Donneill, M.2    Weitz, J.I.3
  • 7
    • 0027216868 scopus 로고
    • Structural and functional characterization of tick anticoagulant peptide (TAP): A potent and selective inhibitor of blood coagulation factor Xa
    • G.P. Vlasuk Structural and functional characterization of tick anticoagulant peptide (TAP): a potent and selective inhibitor of blood coagulation factor Xa Thromb. Haemost. 70 1993 212 216 (Pubitemid 23225484)
    • (1993) Thrombosis and Haemostasis , vol.70 , Issue.1 , pp. 212-216
    • Vlasuk, G.P.1
  • 8
    • 0025683260 scopus 로고
    • Tick anticoagulant peptide: Kinetic analysis of the recombinant inhibitor with blood coagulation factor Xa
    • S.P. Jordan, L. Waxman, D.E. Smith, and G.P. Vlasuk Tick anticoagulant peptide: kinetic analysis of the recombinant inhibitor with blood coagulation factor Xa Biochemistry 29 1990 11095 11100
    • (1990) Biochemistry , vol.29 , pp. 11095-11100
    • Jordan, S.P.1    Waxman, L.2    Smith, D.E.3    Vlasuk, G.P.4
  • 10
    • 0027196767 scopus 로고
    • The serine protease inhibitor family from Ascaris suum: Chemical determination of the five disulfide bridges
    • DOI 10.1006/abbi.1993.1297
    • V.D. Bernard, and R.J. Peanasky The serine protease inhibitor family from Ascaris suum: chemical determination of the five disulfide bridges Arch. Biochem. Biophys. 303 1993 367 376 (Pubitemid 23199835)
    • (1993) Archives of Biochemistry and Biophysics , vol.303 , Issue.2 , pp. 367-376
    • Bernard, V.D.1    Peanasky, R.J.2
  • 12
    • 0037155248 scopus 로고    scopus 로고
    • Molecular characterization of Ancylostoma inhibitors of coagulation factor Xa. Hookworm anticoagulant activity in vitro predicts parasite bloodfeeding in vivo
    • DOI 10.1074/jbc.M109908200
    • L.M. Harrison, A. Nerlinger, R.D. Bungiro, J.L. Cordova, P. Kuzmic, and M. Cappello Molecular characterization of Ancylostoma inhibitors of coagulation factor Xa. Hookworm anticoagulant activity in vitro predicts parasite bloodfeeding in vivo J. Biol. Chem. 277 2002 6223 6229 (Pubitemid 34968413)
    • (2002) Journal of Biological Chemistry , vol.277 , Issue.8 , pp. 6223-6229
    • Harrison, L.M.1    Nerlinger, A.2    Bungiro, R.D.3    Cordova, J.L.4    Kuzmic, P.5    Cappello, M.6
  • 13
    • 0035971227 scopus 로고    scopus 로고
    • Role of zymogen and activated factor X as scaffolds for the inhibition of the blood coagulation factor VIIa-tissue factor complex by recombinant nematode anticoagulant protein c2
    • P.W. Bergum, A. Cruikshank, S.L. Maki, C.R. Kelly, W. Ruf, and G.P. Vlasuk Role of zymogen and activated factor X as scaffolds for the inhibition of the blood coagulation factor VIIa-tissue factor complex by recombinant nematode anticoagulant protein c2 J. Biol. Chem. 276 2001 10063 10071
    • (2001) J. Biol. Chem. , vol.276 , pp. 10063-10071
    • Bergum, P.W.1    Cruikshank, A.2    Maki, S.L.3    Kelly, C.R.4    Ruf, W.5    Vlasuk, G.P.6
  • 14
    • 0037135531 scopus 로고    scopus 로고
    • Nematode anticoagulant protein c2 reveals a site on factor Xa that is important for macromolecular substrate binding to human prothrombinase
    • DOI 10.1074/jbc.M202507200
    • S.K. Buddai, L. Toulokhonova, P.W. Bergum, G.P. Vlasuk, and S. Krishnaswamy Nematode anticoagulant protein c2 reveals a site on factor Xa that is important for macromolecular substrate binding to human prothrombinase J. Biol. Chem. 277 2002 26689 26698 (Pubitemid 34967168)
    • (2002) Journal of Biological Chemistry , vol.277 , Issue.29 , pp. 26689-26698
    • Buddai, S.K.1    Toulokhonova, L.2    Bergum, P.W.3    Vlasuk, G.P.4    Krishnaswamy, S.5
  • 15
    • 0035800075 scopus 로고    scopus 로고
    • Dose-response study of recombinant factor VIIa/tissue factor inhibitor recombinant nematode anticoagulant protein c2 in prevention of postoperative venous thromboembolism in patients undergoing total knee replacement
    • A. Lee, G. Agnelli, H. Buller, J. Ginsberg, J. Heit, W. Rote, G. Vlasuk, L. Costantini, J. Julian, P. Comp, J. van Der Meer, F. Piovella, G. Raskob, and M. Gent Dose-response study of recombinant factor VIIa/tissue factor inhibitor recombinant nematode anticoagulant protein c2 in prevention of postoperative venous thromboembolism in patients undergoing total knee replacement Circulation 104 2001 74 78 (Pubitemid 32623292)
    • (2001) Circulation , vol.104 , Issue.1 , pp. 74-78
    • Lee, A.1    Agnelli, G.2    Buller, H.3    Ginsberg, J.4    Heit, J.5    Rote, W.6    Vlasuk, G.7    Costantini, L.8    Julian, J.9    Comp, P.10    Van Der Meer, J.11    Piovella, F.12    Raskob, G.13    Gent, M.14
  • 16
    • 0033614484 scopus 로고    scopus 로고
    • Characterization of a self-splicing mini-intein and its conversion into autocatalytic N- and C-terminal cleavage elements: Facile production of protein building blocks for protein ligation
    • DOI 10.1016/S0378-1119(99)00103-1, PII S0378111999001031
    • S. Mathys, T.C. Evans, I.C. Chute, H. Wu, S. Chong, J. Benner, X.Q. Liu, and M.Q. Xu Characterization of a self-splicing mini-intein and its conversion into autocatalytic N- and C-terminal cleavage elements: facile production of protein building blocks for protein ligation Gene 231 1999 1 13 (Pubitemid 29307767)
    • (1999) Gene , vol.231 , Issue.1-2 , pp. 1-13
    • Mathys, S.1    Evans Jr., T.C.2    Chute, I.C.3    Wu, H.4    Chong, S.5    Benner, J.6    Liu, X.-Q.7    Xu, M.-Q.8
  • 18
    • 0141862287 scopus 로고    scopus 로고
    • Recombinant nematode anticoagulant protein c2 and other inhibitors targeting blood coagulation factor VIIa/tissue factor
    • DOI 10.1046/j.1365-2796.2003.01224.x
    • A.Y. Lee, and G.P. Vlasuk Recombinant nematode anticoagulant protein c2 and other inhibitors targeting blood coagulation factor VIIa/tissue factor J. Intern. Med. 254 2003 313 321 (Pubitemid 37211255)
    • (2003) Journal of Internal Medicine , vol.254 , Issue.4 , pp. 313-321
    • Lee, A.Y.Y.1    Vlasuk, G.P.2
  • 19
    • 0036873001 scopus 로고    scopus 로고
    • Inhibition of factor VIIa/tissue factor with nematode anticoagulant protein c2: From unique mechanism to a promising new clinical anticoagulant
    • DOI 10.1016/S1050-1738(02)00185-8, PII S1050173802001858
    • G.P. Vlasuk, and W.E. Rote Inhibition of factor VIIa/tissue factor with nematode anticoagulant protein c2: from unique mechanism to a promising new clinical anticoagulant Trends Cardiovasc. Med. 12 2002 325 331 (Pubitemid 36092122)
    • (2002) Trends in Cardiovascular Medicine , vol.12 , Issue.8 , pp. 325-331
    • Vlasuk, G.P.1    Rote, W.E.2
  • 20
    • 0038633316 scopus 로고    scopus 로고
    • Activation of coagulation by administration of recombinant factor VIIa elicits interleukin 6 (IL-6) and IL-8 release in healthy human subjects
    • DOI 10.1128/CDLI.10.3.495-497.2003
    • E. de Jonge, P.W. Friederich, G.P. Vlasuk, W.E. Rote, M.B. Vroom, M. Levi, and T. van der Poll Activation of coagulation by administration of recombinant factor VIIa elicits interleukin 6 (IL-6) and IL-8 release in healthy human subjects Clin. Diagn. Lab. Immunol. 10 2003 495 497 (Pubitemid 36592987)
    • (2003) Clinical and Diagnostic Laboratory Immunology , vol.10 , Issue.3 , pp. 495-497
    • De Jonge, E.1    Friederich, P.W.2    Vlasuk, G.P.3    Rote, W.E.4    Vroom, M.B.5    Levi, M.6    Van Der Poll, T.7
  • 22
    • 3342988385 scopus 로고    scopus 로고
    • Ancylostoma ceylanicum anticoagulant peptide-1: Role of the predicted reactive site amino acid in mediating inhibition of coagulation factors Xa and VIIa
    • DOI 10.1016/j.molbiopara.2004.05.011, PII S0166685104001550
    • J. Mieszczanek, L.M. Harrison, and M. Cappello Ancylostoma ceylanicum anticoagulant peptide-1: role of the predicted reactive site amino acid in mediating inhibition of coagulation factors Xa and VIIa Mol. Biochem. Parasitol. 137 2004 151 159 (Pubitemid 38987952)
    • (2004) Molecular and Biochemical Parasitology , vol.137 , Issue.1 , pp. 151-159
    • Mieszczanek, J.1    Harrison, L.M.2    Cappello, M.3
  • 23
    • 0030249127 scopus 로고    scopus 로고
    • Ancylostoma caninum anticoagulant peptide: Cloning by PCR and expression of soluble, active protein in E. coli
    • DOI 10.1016/0166-6851(96)02658-8
    • M. Cappello, J.M. Hawdon, B.F. Jones, W.P. Kennedy, and P.J. Hotez Ancylostoma caninum anticoagulant peptide: cloning by PCR and expression of soluble, active protein in E. coli Mol. Biochem. Parasitol. 80 1996 113 117 (Pubitemid 26284391)
    • (1996) Molecular and Biochemical Parasitology , vol.80 , Issue.1 , pp. 113-117
    • Cappello, M.1    Hawdon, J.M.2    Jones, B.F.3    Kennedy, W.P.4    Hotez, P.J.5
  • 24
    • 0033894562 scopus 로고    scopus 로고
    • Protein splicing and its applications
    • DOI 10.1016/S0958-1669(00)00113-0
    • F.B. Perler, and E. Adam Protein splicing and its applications Curr. Opin. Biotechnol. 11 2000 377 383 (Pubitemid 30598931)
    • (2000) Current Opinion in Biotechnology , vol.11 , Issue.4 , pp. 377-383
    • Perler, F.B.1    Adam, E.2
  • 25
    • 3342972815 scopus 로고    scopus 로고
    • Formation of tissue factor-factor VIIa-factor Xa complex promotes cellular signaling and migration of human breast cancer cells
    • DOI 10.1111/j.1538-7836.2004.00545.x
    • X. Jiang, M.A. Bailly, T.S. Panetti, M. Cappello, W.H. Konigsberg, and M.E. Bromberg Formation of tissue factor-factor VIIa-factor Xa complex promotes cellular signaling and migration of human breast cancer cells J. Thromb. Haemost. 2 2004 93 101 (Pubitemid 40185625)
    • (2004) Journal of Thrombosis and Haemostasis , vol.2 , Issue.1 , pp. 93-101
    • Jiang, X.1    Bailly, M.A.2    Panetti, T.S.3    Cappello, M.4    Konigsberg, W.H.5    Bromberg, M.E.6
  • 26
    • 0037567437 scopus 로고    scopus 로고
    • Tissue factor/factor VIIa inhibitors block angiogenesis and tumor growth through a nonhemostatic mechanism
    • T.A. Hembrough, G.M. Swartz, A. Papathanassiu, G.P. Vlasuk, W.E. Rote, S.J. Green, and V.S. Pribluda Tissue factor/factor VIIa inhibitors block angiogenesis and tumor growth through a nonhemostatic mechanism Cancer Res. 63 2003 2997 3000 (Pubitemid 36667175)
    • (2003) Cancer Research , vol.63 , Issue.11 , pp. 2997-3000
    • Hembrough, T.A.1    Swartz, G.M.2    Papathanassiu, A.3    Vlasuk, G.P.4    Rote, W.E.5    Green, S.J.6    Pribluda, V.S.7
  • 27
    • 0036243671 scopus 로고    scopus 로고
    • Tissue factor - A therapeutic target for thrombotic disorders
    • DOI 10.1517/14728222.6.2.159
    • D.S. Houston Tissue factor - a therapeutic target for thrombotic disorders Expert Opin. Ther. Targets 6 2002 159 174 (Pubitemid 34477459)
    • (2002) Expert Opinion on Therapeutic Targets , vol.6 , Issue.2 , pp. 159-174
    • Houston, D.S.1
  • 28
    • 0036796103 scopus 로고    scopus 로고
    • Recombinant nematode anticoagulant protein c2, a novel inhibitor of tissue factor-factor VIIa activity, abrogates endotoxin-induced coagulation in chimpanzees
    • A.H. Moons, R.J. Peters, H. Cate, K.A. Bauer, G.P. Vlasuk, H.R. Buller, and M. Levi Recombinant nematode anticoagulant protein c2, a novel inhibitor of tissue factor-factor VIIa activity, abrogates endotoxin-induced coagulation in chimpanzees Thromb. Haemost. 88 2002 627 631 (Pubitemid 35174005)
    • (2002) Thrombosis and Haemostasis , vol.88 , Issue.4 , pp. 627-631
    • Moons, A.H.M.1    Peters, R.J.G.2    Ten Cate, H.3    Bauer, K.A.4    Vlasuk, G.P.5    Buller, H.R.6    Levi, M.7
  • 30
    • 10744222633 scopus 로고    scopus 로고
    • Treatment of Ebola virus infection with a recombinant inhibitor of factor VIIa/tissue factor: A study in rhesus monkeys
    • DOI 10.1016/S0140-6736(03)15012-X
    • T.W. Geisbert, L.E. Hensley, P.B. Jahrling, T. Larsen, J.B. Geisbert, J. Paragas, H.A. Young, T.M. Fredeking, W.E. Rote, and G.P. Vlasuk Treatment of Ebola virus infection with a recombinant inhibitor of factor VIIa/tissue factor: a study in rhesus monkeys Lancet 362 2003 1953 1958 (Pubitemid 37548417)
    • (2003) Lancet , vol.362 , Issue.9400 , pp. 1953-1958
    • Geisbert, T.W.1    Hensley, L.E.2    Jahrling, P.B.3    Larsen, T.4    Geisbert, J.B.5    Paragas, J.6    Young, H.A.7    Fredeking, T.M.8    Rote, W.E.9    Vlasuk, G.P.10


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.