-
1
-
-
46249115827
-
Interferon-inducible antiviral effectors
-
Sadler AJ, Williams BR, (2008) Interferon-inducible antiviral effectors. Nat Rev Immunol 8: 559-568.
-
(2008)
Nat Rev Immunol
, vol.8
, pp. 559-568
-
-
Sadler, A.J.1
Williams, B.R.2
-
2
-
-
33748455338
-
Type I interferons in host defense
-
Stetson DB, Medzhitov R, (2006) Type I interferons in host defense. Immunity 25: 373-381.
-
(2006)
Immunity
, vol.25
, pp. 373-381
-
-
Stetson, D.B.1
Medzhitov, R.2
-
3
-
-
33750976374
-
5′-Triphosphate RNA Is the Ligand for RIG-I
-
Hornung V, Ellegast J, Kim S, Brzozka K, Jung A, et al. (2006) 5′-Triphosphate RNA Is the Ligand for RIG-I. Science 314: 994-997.
-
(2006)
Science
, vol.314
, pp. 994-997
-
-
Hornung, V.1
Ellegast, J.2
Kim, S.3
Brzozka, K.4
Jung, A.5
-
4
-
-
33646342149
-
Differential roles of MDA5 and RIG-I helicases in the recognition of RNA viruses
-
Kato H, Takeuchi O, Sato S, Yoneyama M, Yamamoto M, et al. (2006) Differential roles of MDA5 and RIG-I helicases in the recognition of RNA viruses. Nature 441: 101-105.
-
(2006)
Nature
, vol.441
, pp. 101-105
-
-
Kato, H.1
Takeuchi, O.2
Sato, S.3
Yoneyama, M.4
Yamamoto, M.5
-
5
-
-
33750984771
-
RIG-I-mediated antiviral responses to single-stranded RNA bearing 5′-phosphates
-
Pichlmair A, Schulz O, Tan CP, Naslund TI, Liljestrom P, et al. (2006) RIG-I-mediated antiviral responses to single-stranded RNA bearing 5′-phosphates. Science 314: 997-1001.
-
(2006)
Science
, vol.314
, pp. 997-1001
-
-
Pichlmair, A.1
Schulz, O.2
Tan, C.P.3
Naslund, T.I.4
Liljestrom, P.5
-
6
-
-
3242813113
-
The RNA helicase RIG-I has an essential function in double-stranded RNA-induced innate antiviral responses
-
Yoneyama M, Kikuchi M, Natsukawa T, Shinobu N, Imaizumi T, et al. (2004) The RNA helicase RIG-I has an essential function in double-stranded RNA-induced innate antiviral responses. Nat Immunol 5: 730-737.
-
(2004)
Nat Immunol
, vol.5
, pp. 730-737
-
-
Yoneyama, M.1
Kikuchi, M.2
Natsukawa, T.3
Shinobu, N.4
Imaizumi, T.5
-
7
-
-
77950476766
-
Sensing and signaling in antiviral innate immunity
-
O'Neill LA, Bowie AG, Sensing and signaling in antiviral innate immunity. Curr Biol 20: R328-333.
-
Curr Biol
, vol.20
-
-
O'Neill, L.A.1
Bowie, A.G.2
-
8
-
-
70349459734
-
RIG-I-dependent sensing of poly(dA:dT) through the induction of an RNA polymerase III-transcribed RNA intermediate
-
Ablasser A, Bauernfeind F, Hartmann G, Latz E, Fitzgerald KA, et al. (2009) RIG-I-dependent sensing of poly(dA:dT) through the induction of an RNA polymerase III-transcribed RNA intermediate. Nat Immunol 10: 1065-1072.
-
(2009)
Nat Immunol
, vol.10
, pp. 1065-1072
-
-
Ablasser, A.1
Bauernfeind, F.2
Hartmann, G.3
Latz, E.4
Fitzgerald, K.A.5
-
9
-
-
60749136484
-
An orthogonal proteomic-genomic screen identifies AIM2 as a cytoplasmic DNA sensor for the inflammasome
-
Burckstummer T, Baumann C, Bluml S, Dixit E, Durnberger G, et al. (2009) An orthogonal proteomic-genomic screen identifies AIM2 as a cytoplasmic DNA sensor for the inflammasome. Nat Immunol 10: 266-272.
-
(2009)
Nat Immunol
, vol.10
, pp. 266-272
-
-
Burckstummer, T.1
Baumann, C.2
Bluml, S.3
Dixit, E.4
Durnberger, G.5
-
10
-
-
68049092912
-
RNA polymerase III detects cytosolic DNA and induces type I interferons through the RIG-I pathway
-
Chiu YH, Macmillan JB, Chen ZJ, (2009) RNA polymerase III detects cytosolic DNA and induces type I interferons through the RIG-I pathway. Cell 138: 576-591.
-
(2009)
Cell
, vol.138
, pp. 576-591
-
-
Chiu, Y.H.1
Macmillan, J.B.2
Chen, Z.J.3
-
11
-
-
63649145255
-
AIM2 activates the inflammasome and cell death in response to cytoplasmic DNA
-
Fernandes-Alnemri T, Yu JW, Datta P, Wu J, Alnemri ES, (2009) AIM2 activates the inflammasome and cell death in response to cytoplasmic DNA. Nature 458: 509-513.
-
(2009)
Nature
, vol.458
, pp. 509-513
-
-
Fernandes-Alnemri, T.1
Yu, J.W.2
Datta, P.3
Wu, J.4
Alnemri, E.S.5
-
12
-
-
60749104535
-
HIN-200 proteins regulate caspase activation in response to foreign cytoplasmic DNA
-
Roberts TL, Idris A, Dunn JA, Kelly GM, Burnton CM, et al. (2009) HIN-200 proteins regulate caspase activation in response to foreign cytoplasmic DNA. Science 323: 1057-1060.
-
(2009)
Science
, vol.323
, pp. 1057-1060
-
-
Roberts, T.L.1
Idris, A.2
Dunn, J.A.3
Kelly, G.M.4
Burnton, C.M.5
-
13
-
-
34547143110
-
DAI (DLM-1/ZBP1) is a cytosolic DNA sensor and an activator of innate immune response
-
Takaoka A, Wang Z, Choi MK, Yanai H, Negishi H, et al. (2007) DAI (DLM-1/ZBP1) is a cytosolic DNA sensor and an activator of innate immune response. Nature.
-
(2007)
Nature
-
-
Takaoka, A.1
Wang, Z.2
Choi, M.K.3
Yanai, H.4
Negishi, H.5
-
14
-
-
77958140656
-
IFI16 is an innate immune sensor for intracellular DNA
-
Unterholzner L, Keating SE, Baran M, Horan KA, Jensen SB, et al. (2010) IFI16 is an innate immune sensor for intracellular DNA. Nat Immunol 11: 997-1004.
-
(2010)
Nat Immunol
, vol.11
, pp. 997-1004
-
-
Unterholzner, L.1
Keating, S.E.2
Baran, M.3
Horan, K.A.4
Jensen, S.B.5
-
15
-
-
63649133278
-
AIM2 recognizes cytosolic dsDNA and forms a caspase-1-activating inflammasome with ASC
-
Hornung V, Ablasser A, Charrel-Dennis M, Bauernfeind F, Horvath G, et al. (2009) AIM2 recognizes cytosolic dsDNA and forms a caspase-1-activating inflammasome with ASC. Nature 458: 514-518.
-
(2009)
Nature
, vol.458
, pp. 514-518
-
-
Hornung, V.1
Ablasser, A.2
Charrel-Dennis, M.3
Bauernfeind, F.4
Horvath, G.5
-
16
-
-
34249058290
-
Modulation of the interferon antiviral response by the TBK1/IKKi adaptor protein TANK
-
Guo B, Cheng G, (2007) Modulation of the interferon antiviral response by the TBK1/IKKi adaptor protein TANK. J Biol Chem 282: 11817-11826.
-
(2007)
J Biol Chem
, vol.282
, pp. 11817-11826
-
-
Guo, B.1
Cheng, G.2
-
17
-
-
34447342317
-
SINTBAD, a novel component of innate antiviral immunity, shares a TBK1-binding domain with NAP1 and TANK
-
Ryzhakov G, Randow F, (2007) SINTBAD, a novel component of innate antiviral immunity, shares a TBK1-binding domain with NAP1 and TANK. EMBO J 26: 3180-3190.
-
(2007)
EMBO J
, vol.26
, pp. 3180-3190
-
-
Ryzhakov, G.1
Randow, F.2
-
18
-
-
33845416390
-
NAK-associated protein 1 participates in both the TLR3 and the cytoplasmic pathways in type I IFN induction
-
Sasai M, Shingai M, Funami K, Yoneyama M, Fujita T, et al. (2006) NAK-associated protein 1 participates in both the TLR3 and the cytoplasmic pathways in type I IFN induction. J Immunol 177: 8676-8683.
-
(2006)
J Immunol
, vol.177
, pp. 8676-8683
-
-
Sasai, M.1
Shingai, M.2
Funami, K.3
Yoneyama, M.4
Fujita, T.5
-
19
-
-
27144440523
-
IPS-1, an adaptor triggering RIG-I- and Mda5-mediated type I interferon induction
-
Kawai T, Takahashi K, Sato S, Coban C, Kumar H, et al. (2005) IPS-1, an adaptor triggering RIG-I- and Mda5-mediated type I interferon induction. Nat Immunol 6: 981-988.
-
(2005)
Nat Immunol
, vol.6
, pp. 981-988
-
-
Kawai, T.1
Takahashi, K.2
Sato, S.3
Coban, C.4
Kumar, H.5
-
20
-
-
27144440476
-
Cardif is an adaptor protein in the RIG-I antiviral pathway and is targeted by hepatitis C virus
-
Meylan E, Curran J, Hofmann K, Moradpour D, Binder M, et al. (2005) Cardif is an adaptor protein in the RIG-I antiviral pathway and is targeted by hepatitis C virus. Nature 437: 1167-1172.
-
(2005)
Nature
, vol.437
, pp. 1167-1172
-
-
Meylan, E.1
Curran, J.2
Hofmann, K.3
Moradpour, D.4
Binder, M.5
-
21
-
-
24144461689
-
Identification and Characterization of MAVS, a Mitochondrial Antiviral Signaling Protein that Activates NF-κB and IRF3
-
Seth RB, Sun L, Ea C-K, Chen ZJ, (2005) Identification and Characterization of MAVS, a Mitochondrial Antiviral Signaling Protein that Activates NF-κB and IRF3. Cell 122: 669-682.
-
(2005)
Cell
, vol.122
, pp. 669-682
-
-
Seth, R.B.1
Sun, L.2
Ea, C.-K.3
Chen, Z.J.4
-
22
-
-
53349178089
-
STING is an endoplasmic reticulum adaptor that facilitates innate immune signalling
-
Ishikawa H, Barber GN, (2008) STING is an endoplasmic reticulum adaptor that facilitates innate immune signalling. Nature 455: 674-678.
-
(2008)
Nature
, vol.455
, pp. 674-678
-
-
Ishikawa, H.1
Barber, G.N.2
-
23
-
-
70349943834
-
STING regulates intracellular DNA-mediated, type I interferon-dependent innate immunity
-
Ishikawa H, Ma Z, Barber GN, (2009) STING regulates intracellular DNA-mediated, type I interferon-dependent innate immunity. Nature 461: 788-792.
-
(2009)
Nature
, vol.461
, pp. 788-792
-
-
Ishikawa, H.1
Ma, Z.2
Barber, G.N.3
-
24
-
-
0345991221
-
TIR-containing adapter molecule (TICAM)-2, a bridging adapter recruiting to toll-like receptor 4 TICAM-1 that induces interferon-beta
-
Oshiumi H, Sasai M, Shida K, Fujita T, Matsumoto M, et al. (2003) TIR-containing adapter molecule (TICAM)-2, a bridging adapter recruiting to toll-like receptor 4 TICAM-1 that induces interferon-beta. J Biol Chem 278: 49751-49762.
-
(2003)
J Biol Chem
, vol.278
, pp. 49751-49762
-
-
Oshiumi, H.1
Sasai, M.2
Shida, K.3
Fujita, T.4
Matsumoto, M.5
-
25
-
-
0043176281
-
Role of adaptor TRIF in the MyD88-independent toll-like receptor signaling pathway
-
Yamamoto M, Sato S, Hemmi H, Hoshino K, Kaisho T, et al. (2003) Role of adaptor TRIF in the MyD88-independent toll-like receptor signaling pathway. Science 301: 640-643.
-
(2003)
Science
, vol.301
, pp. 640-643
-
-
Yamamoto, M.1
Sato, S.2
Hemmi, H.3
Hoshino, K.4
Kaisho, T.5
-
26
-
-
77957022292
-
TRAF3: uncovering the real but restricted role in human
-
Bowie AG, (2010) TRAF3: uncovering the real but restricted role in human. Immunity 33: 293-295.
-
(2010)
Immunity
, vol.33
, pp. 293-295
-
-
Bowie, A.G.1
-
27
-
-
0029618697
-
Identification of a member of the interferon regulatory factor family that binds to the interferon-stimulated response element and activates expression of interferon-induced genes
-
Au WC, Moore PA, Lowther W, Juang YT, Pitha PM, (1995) Identification of a member of the interferon regulatory factor family that binds to the interferon-stimulated response element and activates expression of interferon-induced genes. Proc Natl Acad Sci U S A 92: 11657-11661.
-
(1995)
Proc Natl Acad Sci U S A
, vol.92
, pp. 11657-11661
-
-
Au, W.C.1
Moore, P.A.2
Lowther, W.3
Juang, Y.T.4
Pitha, P.M.5
-
28
-
-
0036092049
-
Transcriptional profiling of interferon regulatory factor 3 target genes: direct involvement in the regulation of interferon-stimulated genes
-
Grandvaux N, Servant MJ, tenOever B, Sen GC, Balachandran S, et al. (2002) Transcriptional profiling of interferon regulatory factor 3 target genes: direct involvement in the regulation of interferon-stimulated genes. J Virol 76: 5532-5539.
-
(2002)
J Virol
, vol.76
, pp. 5532-5539
-
-
Grandvaux, N.1
Servant, M.J.2
tenOever, B.3
Sen, G.C.4
Balachandran, S.5
-
29
-
-
17144404177
-
IRF-7 is the master regulator of type-I interferon-dependent immune responses
-
Honda K, Yanai H, Negishi H, Asagiri M, Sato M, et al. (2005) IRF-7 is the master regulator of type-I interferon-dependent immune responses. Nature 434: 772-777.
-
(2005)
Nature
, vol.434
, pp. 772-777
-
-
Honda, K.1
Yanai, H.2
Negishi, H.3
Asagiri, M.4
Sato, M.5
-
30
-
-
0033680737
-
Distinct and essential roles of transcription factors IRF-3 and IRF-7 in response to viruses for IFN-alpha/beta gene induction
-
Sato M, Suemori H, Hata N, Asagiri M, Ogasawara K, et al. (2000) Distinct and essential roles of transcription factors IRF-3 and IRF-7 in response to viruses for IFN-alpha/beta gene induction. Immunity 13: 539-548.
-
(2000)
Immunity
, vol.13
, pp. 539-548
-
-
Sato, M.1
Suemori, H.2
Hata, N.3
Asagiri, M.4
Ogasawara, K.5
-
31
-
-
5444274514
-
Interferon-alpha induction through Toll-like receptors involves a direct interaction of IRF7 with MyD88 and TRAF6
-
Kawai T, Sato S, Ishii KJ, Coban C, Hemmi H, et al. (2004) Interferon-alpha induction through Toll-like receptors involves a direct interaction of IRF7 with MyD88 and TRAF6. Nat Immunol 5: 1061-1068.
-
(2004)
Nat Immunol
, vol.5
, pp. 1061-1068
-
-
Kawai, T.1
Sato, S.2
Ishii, K.J.3
Coban, C.4
Hemmi, H.5
-
32
-
-
33645841633
-
IkappaB kinase-alpha is critical for interferon-alpha production induced by Toll-like receptors 7 and 9
-
Hoshino K, Sugiyama T, Matsumoto M, Tanaka T, Saito M, et al. (2006) IkappaB kinase-alpha is critical for interferon-alpha production induced by Toll-like receptors 7 and 9. Nature 440: 949-953.
-
(2006)
Nature
, vol.440
, pp. 949-953
-
-
Hoshino, K.1
Sugiyama, T.2
Matsumoto, M.3
Tanaka, T.4
Saito, M.5
-
33
-
-
0028070714
-
Functional role of type I and type II interferons in antiviral defense
-
Muller U, Steinhoff U, Reis LF, Hemmi S, Pavlovic J, et al. (1994) Functional role of type I and type II interferons in antiviral defense. Science 264: 1918-1921.
-
(1994)
Science
, vol.264
, pp. 1918-1921
-
-
Muller, U.1
Steinhoff, U.2
Reis, L.F.3
Hemmi, S.4
Pavlovic, J.5
-
34
-
-
36348940608
-
Interferons and viruses: an interplay between induction, signalling, antiviral responses and virus countermeasures
-
Randall RE, Goodbourn S, (2008) Interferons and viruses: an interplay between induction, signalling, antiviral responses and virus countermeasures. J Gen Virol 89: 1-47.
-
(2008)
J Gen Virol
, vol.89
, pp. 1-47
-
-
Randall, R.E.1
Goodbourn, S.2
-
35
-
-
56749133272
-
Viral evasion and subversion of pattern-recognition receptor signalling
-
Bowie AG, Unterholzner L, (2008) Viral evasion and subversion of pattern-recognition receptor signalling. Nat Rev Immunol 8: 911-922.
-
(2008)
Nat Rev Immunol
, vol.8
, pp. 911-922
-
-
Bowie, A.G.1
Unterholzner, L.2
-
36
-
-
70349260534
-
The interferon system and vaccinia virus evasion mechanisms
-
Perdiguero B, Esteban M, (2009) The interferon system and vaccinia virus evasion mechanisms. J Interferon Cytokine Res 29: 581-598.
-
(2009)
J Interferon Cytokine Res
, vol.29
, pp. 581-598
-
-
Perdiguero, B.1
Esteban, M.2
-
37
-
-
0025828433
-
Nucleotide sequence of 42 kbp of vaccinia virus strain WR from near the right inverted terminal repetition
-
Smith GL, Chan YC, Howard ST, (1991) Nucleotide sequence of 42 kbp of vaccinia virus strain WR from near the right inverted terminal repetition. J Gen Virol 72: 1349-1376.
-
(1991)
J Gen Virol
, vol.72
, pp. 1349-1376
-
-
Smith, G.L.1
Chan, Y.C.2
Howard, S.T.3
-
38
-
-
77949443152
-
A poxvirus Bcl-2-like gene family involved in regulation of host immune response: sequence similarity and evolutionary history
-
Gonzalez JM, Esteban M, (2010) A poxvirus Bcl-2-like gene family involved in regulation of host immune response: sequence similarity and evolutionary history. Virol J 7: 59.
-
(2010)
Virol J
, vol.7
, pp. 59
-
-
Gonzalez, J.M.1
Esteban, M.2
-
39
-
-
70350738244
-
Structural basis for targeting of human RNA helicase DDX3 by poxvirus protein K7
-
Oda S, Schroder M, Khan AR, (2009) Structural basis for targeting of human RNA helicase DDX3 by poxvirus protein K7. Structure 17: 1528-1537.
-
(2009)
Structure
, vol.17
, pp. 1528-1537
-
-
Oda, S.1
Schroder, M.2
Khan, A.R.3
-
40
-
-
50849109845
-
Vaccinia virus proteins A52 and B14 Share a Bcl-2-like fold but have evolved to inhibit NF-kappaB rather than apoptosis
-
Graham SC, Bahar MW, Cooray S, Chen RA, Whalen DM, et al. (2008) Vaccinia virus proteins A52 and B14 Share a Bcl-2-like fold but have evolved to inhibit NF-kappaB rather than apoptosis. PLoS Pathog 4: e1000128.
-
(2008)
PLoS Pathog
, vol.4
-
-
Graham, S.C.1
Bahar, M.W.2
Cooray, S.3
Chen, R.A.4
Whalen, D.M.5
-
41
-
-
33845920705
-
Vaccinia virus N1L protein resembles a B cell lymphoma-2 (Bcl-2) family protein
-
Aoyagi M, Zhai D, Jin C, Aleshin AE, Stec B, et al. (2007) Vaccinia virus N1L protein resembles a B cell lymphoma-2 (Bcl-2) family protein. Protein Sci 16: 118-124.
-
(2007)
Protein Sci
, vol.16
, pp. 118-124
-
-
Aoyagi, M.1
Zhai, D.2
Jin, C.3
Aleshin, A.E.4
Stec, B.5
-
42
-
-
34249787896
-
Functional and structural studies of the vaccinia virus virulence factor N1 reveal a Bcl-2-like anti-apoptotic protein
-
Cooray S, Bahar MW, Abrescia NG, McVey CE, Bartlett NW, et al. (2007) Functional and structural studies of the vaccinia virus virulence factor N1 reveal a Bcl-2-like anti-apoptotic protein. J Gen Virol 88: 1656-1666.
-
(2007)
J Gen Virol
, vol.88
, pp. 1656-1666
-
-
Cooray, S.1
Bahar, M.W.2
Abrescia, N.G.3
McVey, C.E.4
Bartlett, N.W.5
-
43
-
-
52149113769
-
Vaccinia virus anti-apoptotic F1L is a novel Bcl-2-like domain-swapped dimer that binds a highly selective subset of BH3-containing death ligands
-
Kvansakul M, Yang H, Fairlie WD, Czabotar PE, Fischer SF, et al. (2008) Vaccinia virus anti-apoptotic F1L is a novel Bcl-2-like domain-swapped dimer that binds a highly selective subset of BH3-containing death ligands. Cell Death Differ 15: 1564-1571.
-
(2008)
Cell Death Differ
, vol.15
, pp. 1564-1571
-
-
Kvansakul, M.1
Yang, H.2
Fairlie, W.D.3
Czabotar, P.E.4
Fischer, S.F.5
-
44
-
-
58149107158
-
Poxvirus K7 Protein Adopts a Bcl-2 Fold: Biochemical Mapping of Its Interactions with Human DEAD Box RNA Helicase DDX3
-
Kalverda AP, Thompson GS, Vogel A, Schroder M, Bowie AG, et al. (2008) Poxvirus K7 Protein Adopts a Bcl-2 Fold: Biochemical Mapping of Its Interactions with Human DEAD Box RNA Helicase DDX3. J Mol Biol.
-
(2008)
J Mol Biol
-
-
Kalverda, A.P.1
Thompson, G.S.2
Vogel, A.3
Schroder, M.4
Bowie, A.G.5
-
45
-
-
4344600796
-
Poxvirus protein N1L targets the I-kappaB kinase complex, inhibits signaling to NF-kappaB by the tumor necrosis factor superfamily of receptors, and inhibits NF-kappaB and IRF3 signaling by toll-like receptors
-
DiPerna G, Stack J, Bowie AG, Boyd A, Kotwal G, et al. (2004) Poxvirus protein N1L targets the I-kappaB kinase complex, inhibits signaling to NF-kappaB by the tumor necrosis factor superfamily of receptors, and inhibits NF-kappaB and IRF3 signaling by toll-like receptors. J Biol Chem 279: 36570-36578.
-
(2004)
J Biol Chem
, vol.279
, pp. 36570-36578
-
-
DiPerna, G.1
Stack, J.2
Bowie, A.G.3
Boyd, A.4
Kotwal, G.5
-
46
-
-
1642421758
-
Poxvirus genomes: a phylogenetic analysis
-
Gubser C, Hue S, Kellam P, Smith GL, (2004) Poxvirus genomes: a phylogenetic analysis. J Gen Virol 85: 105-117.
-
(2004)
J Gen Virol
, vol.85
, pp. 105-117
-
-
Gubser, C.1
Hue, S.2
Kellam, P.3
Smith, G.L.4
-
47
-
-
40349085775
-
Inhibition of IkappaB kinase by vaccinia virus virulence factor B14
-
Chen RA, Ryzhakov G, Cooray S, Randow F, Smith GL, (2008) Inhibition of IkappaB kinase by vaccinia virus virulence factor B14. PLoS Pathog 4: e22.
-
(2008)
PLoS Pathog
, vol.4
-
-
Chen, R.A.1
Ryzhakov, G.2
Cooray, S.3
Randow, F.4
Smith, G.L.5
-
48
-
-
0031893220
-
Virus-dependent phosphorylation of the IRF-3 transcription factor regulates nuclear translocation, transactivation potential, and proteasome-mediated degradation
-
Lin R, Heylbroeck C, Pitha PM, Hiscott J, (1998) Virus-dependent phosphorylation of the IRF-3 transcription factor regulates nuclear translocation, transactivation potential, and proteasome-mediated degradation. Mol Cell Biol 18: 2986-2996.
-
(1998)
Mol Cell Biol
, vol.18
, pp. 2986-2996
-
-
Lin, R.1
Heylbroeck, C.2
Pitha, P.M.3
Hiscott, J.4
-
49
-
-
33748051738
-
IRFs: master regulators of signalling by Toll-like receptors and cytosolic pattern-recognition receptors
-
Honda K, Taniguchi T, (2006) IRFs: master regulators of signalling by Toll-like receptors and cytosolic pattern-recognition receptors. Nat Rev Immunol 6: 644-658.
-
(2006)
Nat Rev Immunol
, vol.6
, pp. 644-658
-
-
Honda, K.1
Taniguchi, T.2
-
50
-
-
5444274514
-
Interferon-alpha induction through Toll-like receptors involves a direct interaction of IRF7 with MyD88 and TRAF6
-
Kawai T, Sato S, Ishii KJ, Coban C, Hemmi H, et al. (2004) Interferon-alpha induction through Toll-like receptors involves a direct interaction of IRF7 with MyD88 and TRAF6. Nat Immunol 5: 1061-1068.
-
(2004)
Nat Immunol
, vol.5
, pp. 1061-1068
-
-
Kawai, T.1
Sato, S.2
Ishii, K.J.3
Coban, C.4
Hemmi, H.5
-
51
-
-
70350450808
-
The TBK1 adaptor and autophagy receptor NDP52 restricts the proliferation of ubiquitin-coated bacteria
-
Thurston TL, Ryzhakov G, Bloor S, von Muhlinen N, Randow F, (2009) The TBK1 adaptor and autophagy receptor NDP52 restricts the proliferation of ubiquitin-coated bacteria. Nat Immunol 10: 1215-1221.
-
(2009)
Nat Immunol
, vol.10
, pp. 1215-1221
-
-
Thurston, T.L.1
Ryzhakov, G.2
Bloor, S.3
von Muhlinen, N.4
Randow, F.5
-
52
-
-
67649823926
-
Use of the pharmacological inhibitor BX795 to study the regulation and physiological roles of TBK1 and IkappaB kinase epsilon: a distinct upstream kinase mediates Ser-172 phosphorylation and activation
-
Clark K, Plater L, Peggie M, Cohen P, (2009) Use of the pharmacological inhibitor BX795 to study the regulation and physiological roles of TBK1 and IkappaB kinase epsilon: a distinct upstream kinase mediates Ser-172 phosphorylation and activation. J Biol Chem 284: 14136-14146.
-
(2009)
J Biol Chem
, vol.284
, pp. 14136-14146
-
-
Clark, K.1
Plater, L.2
Peggie, M.3
Cohen, P.4
-
53
-
-
20144372620
-
High-throughput mapping of a dynamic signaling network in mammalian cells
-
Barrios-Rodiles M, Brown KR, Ozdamar B, Bose R, Liu Z, et al. (2005) High-throughput mapping of a dynamic signaling network in mammalian cells. Science 307: 1621-1625.
-
(2005)
Science
, vol.307
, pp. 1621-1625
-
-
Barrios-Rodiles, M.1
Brown, K.R.2
Ozdamar, B.3
Bose, R.4
Liu, Z.5
-
54
-
-
41149168106
-
Kinetic analysis of a complete poxvirus transcriptome reveals an immediate-early class of genes
-
Assarsson E, Greenbaum JA, Sundstrom M, Schaffer L, Hammond JA, et al. (2008) Kinetic analysis of a complete poxvirus transcriptome reveals an immediate-early class of genes. Proc Natl Acad Sci U S A 105: 2140-2145.
-
(2008)
Proc Natl Acad Sci U S A
, vol.105
, pp. 2140-2145
-
-
Assarsson, E.1
Greenbaum, J.A.2
Sundstrom, M.3
Schaffer, L.4
Hammond, J.A.5
-
55
-
-
0024094011
-
Vaccinia virus gene D8 encodes a virion transmembrane protein
-
Niles EG, Seto J, (1988) Vaccinia virus gene D8 encodes a virion transmembrane protein. J Virol 62: 3772-3778.
-
(1988)
J Virol
, vol.62
, pp. 3772-3778
-
-
Niles, E.G.1
Seto, J.2
-
56
-
-
17144366260
-
Vaccinia virus protein A46R targets multiple Toll-like-interleukin-1 receptor adaptors and contributes to virulence
-
Stack J, Haga IR, Schroder M, Bartlett NW, Maloney G, et al. (2005) Vaccinia virus protein A46R targets multiple Toll-like-interleukin-1 receptor adaptors and contributes to virulence. J Exp Med 201: 1007-1018.
-
(2005)
J Exp Med
, vol.201
, pp. 1007-1018
-
-
Stack, J.1
Haga, I.R.2
Schroder, M.3
Bartlett, N.W.4
Maloney, G.5
-
57
-
-
0037415598
-
The poxvirus protein A52R targets Toll-like receptor signaling complexes to suppress host defense
-
Harte MT, Haga IR, Maloney G, Gray P, Reading PC, et al. (2003) The poxvirus protein A52R targets Toll-like receptor signaling complexes to suppress host defense. J Exp Med 197: 343-351.
-
(2003)
J Exp Med
, vol.197
, pp. 343-351
-
-
Harte, M.T.1
Haga, I.R.2
Maloney, G.3
Gray, P.4
Reading, P.C.5
-
58
-
-
49149113373
-
Viral targeting of DEAD box protein 3 reveals its role in TBK1/IKKepsilon-mediated IRF activation
-
Schroder M, Baran M, Bowie AG, (2008) Viral targeting of DEAD box protein 3 reveals its role in TBK1/IKKepsilon-mediated IRF activation. EMBO J 27: 2147-2157.
-
(2008)
EMBO J
, vol.27
, pp. 2147-2157
-
-
Schroder, M.1
Baran, M.2
Bowie, A.G.3
-
59
-
-
10744221904
-
Identification of NAP1, a regulatory subunit of IkappaB kinase-related kinases that potentiates NF-kappaB signaling
-
Fujita F, Taniguchi Y, Kato T, Narita Y, Furuya A, et al. (2003) Identification of NAP1, a regulatory subunit of IkappaB kinase-related kinases that potentiates NF-kappaB signaling. Mol Cell Biol 23: 7780-7793.
-
(2003)
Mol Cell Biol
, vol.23
, pp. 7780-7793
-
-
Fujita, F.1
Taniguchi, Y.2
Kato, T.3
Narita, Y.4
Furuya, A.5
-
60
-
-
0033485542
-
NF-kappaB activation by a signaling complex containing TRAF2, TANK and TBK1, a novel IKK-related kinase
-
Pomerantz JL, Baltimore D, (1999) NF-kappaB activation by a signaling complex containing TRAF2, TANK and TBK1, a novel IKK-related kinase. EMBO J 18: 6694-6704.
-
(1999)
EMBO J
, vol.18
, pp. 6694-6704
-
-
Pomerantz, J.L.1
Baltimore, D.2
-
61
-
-
67650230347
-
Severe acute respiratory syndrome coronavirus M protein inhibits type I interferon production by impeding the formation of TRAF3.TANK.TBK1/IKKepsilon complex
-
Siu KL, Kok KH, Ng MH, Poon VK, Yuen KY, et al. (2009) Severe acute respiratory syndrome coronavirus M protein inhibits type I interferon production by impeding the formation of TRAF3.TANK.TBK1/IKKepsilon complex. J Biol Chem 284: 16202-16209.
-
(2009)
J Biol Chem
, vol.284
, pp. 16202-16209
-
-
Siu, K.L.1
Kok, K.H.2
Ng, M.H.3
Poon, V.K.4
Yuen, K.Y.5
-
62
-
-
69249206610
-
Vaccinia virus vaccines: past, present and future
-
Jacobs BL, Langland JO, Kibler KV, Denzler KL, White SD, et al. (2009) Vaccinia virus vaccines: past, present and future. Antiviral Res 84: 1-13.
-
(2009)
Antiviral Res
, vol.84
, pp. 1-13
-
-
Jacobs, B.L.1
Langland, J.O.2
Kibler, K.V.3
Denzler, K.L.4
White, S.D.5
-
63
-
-
57749201655
-
Targeted and armed oncolytic poxviruses: a novel multi-mechanistic therapeutic class for cancer
-
Kirn DH, Thorne SH, (2009) Targeted and armed oncolytic poxviruses: a novel multi-mechanistic therapeutic class for cancer. Nat Rev Cancer 9: 64-71.
-
(2009)
Nat Rev Cancer
, vol.9
, pp. 64-71
-
-
Kirn, D.H.1
Thorne, S.H.2
-
64
-
-
0027980628
-
Vaccinia virus gene A36R encodes a M(r) 43-50 K protein on the surface of extracellular enveloped virus
-
Parkinson JE, Smith GL, (1994) Vaccinia virus gene A36R encodes a M(r) 43-50 K protein on the surface of extracellular enveloped virus. Virology 204: 376-390.
-
(1994)
Virology
, vol.204
, pp. 376-390
-
-
Parkinson, J.E.1
Smith, G.L.2
-
65
-
-
0023941341
-
Escherichia coli gpt gene provides dominant selection for vaccinia virus open reading frame expression vectors
-
Falkner FG, Moss B, (1988) Escherichia coli gpt gene provides dominant selection for vaccinia virus open reading frame expression vectors. J Virol 62: 1849-1854.
-
(1988)
J Virol
, vol.62
, pp. 1849-1854
-
-
Falkner, F.G.1
Moss, B.2
-
66
-
-
0025129596
-
Biological characterization of recombinant vaccinia viruses in mice infected by the respiratory route
-
Williamson JD, Reith RW, Jeffrey LJ, Arrand JR, Mackett M, (1990) Biological characterization of recombinant vaccinia viruses in mice infected by the respiratory route. J Gen Virol 71 (Pt 11): 2761-2767.
-
(1990)
J Gen Virol
, vol.71
, Issue.Pt 11
, pp. 2761-2767
-
-
Williamson, J.D.1
Reith, R.W.2
Jeffrey, L.J.3
Arrand, J.R.4
Mackett, M.5
-
67
-
-
0026646637
-
A soluble receptor for interleukin-1 beta encoded by vaccinia virus: a novel mechanism of virus modulation of the host response to infection
-
Alcami A, Smith GL, (1992) A soluble receptor for interleukin-1 beta encoded by vaccinia virus: a novel mechanism of virus modulation of the host response to infection. Cell 71: 153-167.
-
(1992)
Cell
, vol.71
, pp. 153-167
-
-
Alcami, A.1
Smith, G.L.2
-
68
-
-
0032882443
-
A model for vaccinia virus pathogenesis and immunity based on intradermal injection of mouse ear pinnae
-
Tscharke DC, Smith GL, (1999) A model for vaccinia virus pathogenesis and immunity based on intradermal injection of mouse ear pinnae. J Gen Virol 80 (Pt 10): 2751-2755.
-
(1999)
J Gen Virol
, vol.80
, Issue.Pt 10
, pp. 2751-2755
-
-
Tscharke, D.C.1
Smith, G.L.2
-
69
-
-
0036327752
-
Dermal infection with vaccinia virus reveals roles for virus proteins not seen using other inoculation routes
-
Tscharke DC, Reading PC, Smith GL, (2002) Dermal infection with vaccinia virus reveals roles for virus proteins not seen using other inoculation routes. J Gen Virol 83: 1977-1986.
-
(2002)
J Gen Virol
, vol.83
, pp. 1977-1986
-
-
Tscharke, D.C.1
Reading, P.C.2
Smith, G.L.3
|