Protein Conformations Can Be Probed in Top-Down HDX MS Experiments Utilizing Electron Transfer Dissociation of Protein Ions Without Hydrogen Scrambling

Journal of the American Society for Mass Spectrometry

Volumn 20, Issue 8, 2009, Pages 1514-1517

  Abzalimov, Rinat R ^a   Kaplan, Desmond A ^b   Easterling, Michael L ^b   Kaltashov, Igor A ^a  

^a UNIVERSITY OF MASSACHUSETTS   (United States)

^b BRUKER DALTONIK GMBH   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

DENATURING CONDITIONS; DEUTERIUM CONTENT; ELECTRON-TRANSFER DISSOCIATION; FLEXIBLE SEGMENTS; FLUORANTHENE; FRAGMENT IONS; GASPHASE; HIGHER-ORDER STRUCTURE; HYDROGEN SCRAMBLING; HYDROGEN/DEUTERIUM EXCHANGE; INTACT PROTEINS; ISOTOPIC LABELING; LOCAL INFORMATION; N-TERMINAL; PROTEIN CONFORMATION; PROTEIN IONS; PROTEIN MOLECULES; PROTEIN SEGMENTS; RADICAL ANIONS; TOPDOWN;

CONFORMATIONS; DEUTERIUM; DISSOCIATION; ELECTROSPRAY IONIZATION; FREE RADICAL REACTIONS; HYDROGEN; ION EXCHANGE; IONIZATION OF GASES; LABELS;

IONS;

DEUTERIUM; HYDROGEN;

AMINO TERMINAL SEQUENCE; ARTICLE; DEUTERIUM HYDROGEN EXCHANGE; DISSOCIATION; ELECTRON TRANSPORT; ELECTROSPRAY MASS SPECTROMETRY; MOLECULAR DYNAMICS; MOLECULAR PROBE; PROTEIN CONFORMATION; PROTEIN STRUCTURE;

ELECTRON TRANSPORT; HYDROGEN; PROTEIN CONFORMATION; PROTEINS; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION;

EID: 67650763014     PISSN: 10440305     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jasms.2009.04.006     Document Type: Article

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