-
1
-
-
79952284127
-
Hallmarks of cancer: the next generation
-
Hanahan D., Weinberg R.A. Hallmarks of cancer: the next generation. Cell 2011, 144:646-674.
-
(2011)
Cell
, vol.144
, pp. 646-674
-
-
Hanahan, D.1
Weinberg, R.A.2
-
2
-
-
58149345546
-
Co-evolution of tumor cells and their microenvironment
-
Polyak K., Haviv I., Campbell I.G. Co-evolution of tumor cells and their microenvironment. Trends Genet 2009, 25:30-38.
-
(2009)
Trends Genet
, vol.25
, pp. 30-38
-
-
Polyak, K.1
Haviv, I.2
Campbell, I.G.3
-
3
-
-
43249121177
-
Stromal gene expression predicts clinical outcome in breast cancer
-
Finak G., Bertos N., Pepin F., Sadekova S., Souleimanova M., Zhao H., Chen H., Omeroglu G., Meterissian S., Omeroglu A., et al. Stromal gene expression predicts clinical outcome in breast cancer. Nat Med 2008, 14:518-527.
-
(2008)
Nat Med
, vol.14
, pp. 518-527
-
-
Finak, G.1
Bertos, N.2
Pepin, F.3
Sadekova, S.4
Souleimanova, M.5
Zhao, H.6
Chen, H.7
Omeroglu, G.8
Meterissian, S.9
Omeroglu, A.10
-
4
-
-
77957942216
-
Variations in stromal signatures in breast and colorectal cancer metastases
-
Webster J.A., Beck A.H., Sharma M., Espinosa I., Weigelt B., Schreuder M., Montgomery K.D., Jensen K.C., van de Rijn M., West R. Variations in stromal signatures in breast and colorectal cancer metastases. J Pathol 2010, 222:158-165.
-
(2010)
J Pathol
, vol.222
, pp. 158-165
-
-
Webster, J.A.1
Beck, A.H.2
Sharma, M.3
Espinosa, I.4
Weigelt, B.5
Schreuder, M.6
Montgomery, K.D.7
Jensen, K.C.8
van de Rijn, M.9
West, R.10
-
5
-
-
77955928161
-
Tumors as organs: complex tissues that interface with the entire organism
-
Egeblad M., Nakasone E.S., Werb Z. Tumors as organs: complex tissues that interface with the entire organism. Dev Cell 2010, 18:884-901.
-
(2010)
Dev Cell
, vol.18
, pp. 884-901
-
-
Egeblad, M.1
Nakasone, E.S.2
Werb, Z.3
-
6
-
-
77956460390
-
Environmental control of invasiveness and metastatic dissemination of tumor cells: the role of tumor cell-host cell interactions
-
Calorini L., Bianchini F. Environmental control of invasiveness and metastatic dissemination of tumor cells: the role of tumor cell-host cell interactions. Cell Commun Signal 2010, 8:24.
-
(2010)
Cell Commun Signal
, vol.8
, pp. 24
-
-
Calorini, L.1
Bianchini, F.2
-
7
-
-
77956883321
-
Activation of fibroblasts in cancer stroma
-
Rasanen K., Vaheri A. Activation of fibroblasts in cancer stroma. Exp Cell Res 2010, 316:2713-2722.
-
(2010)
Exp Cell Res
, vol.316
, pp. 2713-2722
-
-
Rasanen, K.1
Vaheri, A.2
-
8
-
-
77950346282
-
Immunity, inflammation, and cancer
-
Grivennikov S.I., Greten F.R., Karin M. Immunity, inflammation, and cancer. Cell 2010, 140:883-899.
-
(2010)
Cell
, vol.140
, pp. 883-899
-
-
Grivennikov, S.I.1
Greten, F.R.2
Karin, M.3
-
9
-
-
39649098678
-
Tumour immunity: effector response to tumour and role of the microenvironment
-
Mantovani A., Romero P., Palucka A.K., Marincola F.M. Tumour immunity: effector response to tumour and role of the microenvironment. Lancet 2008, 371:771-783.
-
(2008)
Lancet
, vol.371
, pp. 771-783
-
-
Mantovani, A.1
Romero, P.2
Palucka, A.K.3
Marincola, F.M.4
-
10
-
-
77953988924
-
Targeting the tumour vasculature: insights from physiological angiogenesis
-
Chung A.S., Lee J., Ferrara N. Targeting the tumour vasculature: insights from physiological angiogenesis. Nat Rev Cancer 2010, 10:505-514.
-
(2010)
Nat Rev Cancer
, vol.10
, pp. 505-514
-
-
Chung, A.S.1
Lee, J.2
Ferrara, N.3
-
11
-
-
3042822267
-
Cancer and the chemokine network
-
Balkwill F. Cancer and the chemokine network. Nat Rev Cancer 2004, 4:540-550.
-
(2004)
Nat Rev Cancer
, vol.4
, pp. 540-550
-
-
Balkwill, F.1
-
12
-
-
31344442461
-
Inflammation-associated immune suppression in cancer: the roles played by cytokines, chemokines and additional mediators
-
Ben-Baruch A. Inflammation-associated immune suppression in cancer: the roles played by cytokines, chemokines and additional mediators. Semin Cancer Biol 2006, 16:38-52.
-
(2006)
Semin Cancer Biol
, vol.16
, pp. 38-52
-
-
Ben-Baruch, A.1
-
13
-
-
47949096781
-
Cancer-related inflammation
-
Mantovani A., Allavena P., Sica A., Balkwill F. Cancer-related inflammation. Nature 2008, 454:436-444.
-
(2008)
Nature
, vol.454
, pp. 436-444
-
-
Mantovani, A.1
Allavena, P.2
Sica, A.3
Balkwill, F.4
-
14
-
-
20444436815
-
Macrophages promote the invasion of breast carcinoma cells via a colony-stimulating factor-1/epidermal growth factor paracrine loop
-
Goswami S., Sahai E., Wyckoff J.B., Cammer M., Cox D., Pixley F.J., Stanley E.R., Segall J.E., Condeelis J.S. Macrophages promote the invasion of breast carcinoma cells via a colony-stimulating factor-1/epidermal growth factor paracrine loop. Cancer Res 2005, 65:5278-5283.
-
(2005)
Cancer Res
, vol.65
, pp. 5278-5283
-
-
Goswami, S.1
Sahai, E.2
Wyckoff, J.B.3
Cammer, M.4
Cox, D.5
Pixley, F.J.6
Stanley, E.R.7
Segall, J.E.8
Condeelis, J.S.9
-
15
-
-
4944229701
-
A paracrine loop between tumor cells and macrophages is required for tumor cell migration in mammary tumors
-
Wyckoff J., Wang W., Lin E.Y., Wang Y., Pixley F., Stanley E.R., Graf T., Pollard J.W., Segall J., Condeelis J. A paracrine loop between tumor cells and macrophages is required for tumor cell migration in mammary tumors. Cancer Res 2004, 64:7022-7029.
-
(2004)
Cancer Res
, vol.64
, pp. 7022-7029
-
-
Wyckoff, J.1
Wang, W.2
Lin, E.Y.3
Wang, Y.4
Pixley, F.5
Stanley, E.R.6
Graf, T.7
Pollard, J.W.8
Segall, J.9
Condeelis, J.10
-
16
-
-
78650563018
-
Autocrine TGF-beta and stromal cell-derived factor-1 (SDF-1) signaling drives the evolution of tumor-promoting mammary stromal myofibroblasts
-
Kojima Y., Acar A., Eaton E.N., Mellody K.T., Scheel C., Ben-Porath I., Onder T.T., Wang Z.C., Richardson A.L., Weinberg R.A., et al. Autocrine TGF-beta and stromal cell-derived factor-1 (SDF-1) signaling drives the evolution of tumor-promoting mammary stromal myofibroblasts. Proc Natl Acad Sci USA 2010, 107:20009-20014.
-
(2010)
Proc Natl Acad Sci USA
, vol.107
, pp. 20009-20014
-
-
Kojima, Y.1
Acar, A.2
Eaton, E.N.3
Mellody, K.T.4
Scheel, C.5
Ben-Porath, I.6
Onder, T.T.7
Wang, Z.C.8
Richardson, A.L.9
Weinberg, R.A.10
-
17
-
-
34948896045
-
Mesenchymal stem cells within tumour stroma promote breast cancer metastasis
-
Karnoub A.E., Dash A.B., Vo A.P., Sullivan A., Brooks M.W., Bell G.W., Richardson A.L., Polyak K., Tubo R., Weinberg R.A. Mesenchymal stem cells within tumour stroma promote breast cancer metastasis. Nature 2007, 449:557-563.
-
(2007)
Nature
, vol.449
, pp. 557-563
-
-
Karnoub, A.E.1
Dash, A.B.2
Vo, A.P.3
Sullivan, A.4
Brooks, M.W.5
Bell, G.W.6
Richardson, A.L.7
Polyak, K.8
Tubo, R.9
Weinberg, R.A.10
-
18
-
-
79251586559
-
Breast cancer cells induce cancer-associated fibroblasts to secrete hepatocyte growth factor to enhance breast tumorigenesis
-
Tyan S.W., Kuo W.H., Huang C.K., Pan C.C., Shew J.Y., Chang K.J., Lee E.Y., Lee W.H. Breast cancer cells induce cancer-associated fibroblasts to secrete hepatocyte growth factor to enhance breast tumorigenesis. PLoS One 2010, 6:e15313.
-
(2010)
PLoS One
, vol.6
-
-
Tyan, S.W.1
Kuo, W.H.2
Huang, C.K.3
Pan, C.C.4
Shew, J.Y.5
Chang, K.J.6
Lee, E.Y.7
Lee, W.H.8
-
19
-
-
5444248307
-
Tenascin-C and SF/HGF produced by myofibroblasts in vitro provide convergent pro-invasive signals to human colon cancer cells through RhoA and Rac
-
De Wever O., Nguyen Q.D., Van Hoorde L., Bracke M., Bruyneel E., Gespach C., Mareel M. Tenascin-C and SF/HGF produced by myofibroblasts in vitro provide convergent pro-invasive signals to human colon cancer cells through RhoA and Rac. FASEB J 2004, 18:1016-1018.
-
(2004)
FASEB J
, vol.18
, pp. 1016-1018
-
-
De Wever, O.1
Nguyen, Q.D.2
Van Hoorde, L.3
Bracke, M.4
Bruyneel, E.5
Gespach, C.6
Mareel, M.7
-
20
-
-
0842288323
-
TGF-beta signaling in fibroblasts modulates the oncogenic potential of adjacent epithelia
-
Bhowmick N.A., Chytil A., Plieth D., Gorska A.E., Dumont N., Shappell S., Washington M.K., Neilson E.G., Moses H.L. TGF-beta signaling in fibroblasts modulates the oncogenic potential of adjacent epithelia. Science 2004, 303:848-851.
-
(2004)
Science
, vol.303
, pp. 848-851
-
-
Bhowmick, N.A.1
Chytil, A.2
Plieth, D.3
Gorska, A.E.4
Dumont, N.5
Shappell, S.6
Washington, M.K.7
Neilson, E.G.8
Moses, H.L.9
-
21
-
-
18844428327
-
Stromal fibroblasts present in invasive human breast carcinomas promote tumor growth and angiogenesis through elevated SDF-1/CXCL12 secretion
-
Orimo A., Gupta P.B., Sgroi D.C., Arenzana-Seisdedos F., Delaunay T., Naeem R., Carey V.J., Richardson A.L., Weinberg R.A. Stromal fibroblasts present in invasive human breast carcinomas promote tumor growth and angiogenesis through elevated SDF-1/CXCL12 secretion. Cell 2005, 121:335-348.
-
(2005)
Cell
, vol.121
, pp. 335-348
-
-
Orimo, A.1
Gupta, P.B.2
Sgroi, D.C.3
Arenzana-Seisdedos, F.4
Delaunay, T.5
Naeem, R.6
Carey, V.J.7
Richardson, A.L.8
Weinberg, R.A.9
-
22
-
-
76349096670
-
Cancer-associated fibroblasts are activated in incipient neoplasia to orchestrate tumor-promoting inflammation in an NF-kappaB-dependent manner
-
Erez N., Truitt M., Olson P., Arron S.T., Hanahan D. Cancer-associated fibroblasts are activated in incipient neoplasia to orchestrate tumor-promoting inflammation in an NF-kappaB-dependent manner. Cancer Cell 2010, 17:135-147.
-
(2010)
Cancer Cell
, vol.17
, pp. 135-147
-
-
Erez, N.1
Truitt, M.2
Olson, P.3
Arron, S.T.4
Hanahan, D.5
-
23
-
-
4644237613
-
Specific recruitment of regulatory T cells in ovarian carcinoma fosters immune privilege and predicts reduced survival
-
Curiel T.J., Coukos G., Zou L., Alvarez X., Cheng P., Mottram P., Evdemon-Hogan M., Conejo-Garcia J.R., Zhang L., Burow M., et al. Specific recruitment of regulatory T cells in ovarian carcinoma fosters immune privilege and predicts reduced survival. Nat Med 2004, 10:942-949.
-
(2004)
Nat Med
, vol.10
, pp. 942-949
-
-
Curiel, T.J.1
Coukos, G.2
Zou, L.3
Alvarez, X.4
Cheng, P.5
Mottram, P.6
Evdemon-Hogan, M.7
Conejo-Garcia, J.R.8
Zhang, L.9
Burow, M.10
-
24
-
-
33646164362
-
Transforming growth factor-beta regulation of immune responses
-
Li M.O., Wan Y.Y., Sanjabi S., Robertson A.K., Flavell R.A. Transforming growth factor-beta regulation of immune responses. Annu Rev Immunol 2006, 24:99-146.
-
(2006)
Annu Rev Immunol
, vol.24
, pp. 99-146
-
-
Li, M.O.1
Wan, Y.Y.2
Sanjabi, S.3
Robertson, A.K.4
Flavell, R.A.5
-
25
-
-
69249222379
-
Polarization of tumor-associated neutrophil phenotype by TGF-beta: "N1" versus "N2" TAN
-
Fridlender Z.G., Sun J., Kim S., Kapoor V., Cheng G., Ling L., Worthen G.S., Albelda S.M. Polarization of tumor-associated neutrophil phenotype by TGF-beta: "N1" versus "N2" TAN. Cancer Cell 2009, 16:183-194.
-
(2009)
Cancer Cell
, vol.16
, pp. 183-194
-
-
Fridlender, Z.G.1
Sun, J.2
Kim, S.3
Kapoor, V.4
Cheng, G.5
Ling, L.6
Worthen, G.S.7
Albelda, S.M.8
-
26
-
-
79952193038
-
Tumour-infiltrating regulatory T cells stimulate mammary cancer metastasis through RANKL-RANK signalling
-
Tan W., Zhang W., Strasner A., Grivennikov S., Cheng J.Q., Hoffman R.M., Karin M. Tumour-infiltrating regulatory T cells stimulate mammary cancer metastasis through RANKL-RANK signalling. Nature 2011, 470:548-553.
-
(2011)
Nature
, vol.470
, pp. 548-553
-
-
Tan, W.1
Zhang, W.2
Strasner, A.3
Grivennikov, S.4
Cheng, J.Q.5
Hoffman, R.M.6
Karin, M.7
-
27
-
-
67651160649
-
CD4(+) T cells regulate pulmonary metastasis of mammary carcinomas by enhancing protumor properties of macrophages
-
DeNardo D.G., Barreto J.B., Andreu P., Vasquez L., Tawfik D., Kolhatkar N., Coussens L.M. CD4(+) T cells regulate pulmonary metastasis of mammary carcinomas by enhancing protumor properties of macrophages. Cancer Cell 2009, 16:91-102.
-
(2009)
Cancer Cell
, vol.16
, pp. 91-102
-
-
DeNardo, D.G.1
Barreto, J.B.2
Andreu, P.3
Vasquez, L.4
Tawfik, D.5
Kolhatkar, N.6
Coussens, L.M.7
-
28
-
-
79551540808
-
Role of the endothelium during tumor cell metastasis: is the endothelium a barrier or a promoter for cell invasion and metastasis?
-
Mierke C.T. Role of the endothelium during tumor cell metastasis: is the endothelium a barrier or a promoter for cell invasion and metastasis?. J Biophys 2008, 2008:183516.
-
(2008)
J Biophys
, vol.2008
, pp. 183516
-
-
Mierke, C.T.1
-
29
-
-
78649637459
-
Chemokines at the crossroads of tumor-fibroblast interactions that promote malignancy
-
Mishra P., Banerjee D., Ben-Baruch A Chemokines at the crossroads of tumor-fibroblast interactions that promote malignancy. J Leukoc Biol 2011, 89:31-39.
-
(2011)
J Leukoc Biol
, vol.89
, pp. 31-39
-
-
Mishra, P.1
Banerjee, D.2
Ben-Baruch, A.3
-
31
-
-
63149088164
-
Trophic macrophages in development and disease
-
Pollard J.W. Trophic macrophages in development and disease. Nat Rev Immunol 2009, 9:259-270.
-
(2009)
Nat Rev Immunol
, vol.9
, pp. 259-270
-
-
Pollard, J.W.1
-
33
-
-
33645739790
-
Tumor stroma and regulation of cancer development
-
Tlsty T.D., Coussens L.M. Tumor stroma and regulation of cancer development. Annu Rev Pathol 2006, 1:119-150.
-
(2006)
Annu Rev Pathol
, vol.1
, pp. 119-150
-
-
Tlsty, T.D.1
Coussens, L.M.2
-
34
-
-
0035835829
-
Heterotypic signaling between epithelial tumor cells and fibroblasts in carcinoma formation
-
Elenbaas B., Weinberg R.A. Heterotypic signaling between epithelial tumor cells and fibroblasts in carcinoma formation. Exp Cell Res 2001, 264:169-184.
-
(2001)
Exp Cell Res
, vol.264
, pp. 169-184
-
-
Elenbaas, B.1
Weinberg, R.A.2
-
35
-
-
77954564655
-
Matricellular proteins: from homeostasis to inflammation, cancer, and metastasis
-
Chiodoni C., Colombo M.P., Sangaletti S Matricellular proteins: from homeostasis to inflammation, cancer, and metastasis. Cancer Metastasis Rev 2010, 29:295-307.
-
(2010)
Cancer Metastasis Rev
, vol.29
, pp. 295-307
-
-
Chiodoni, C.1
Colombo, M.P.2
Sangaletti, S.3
-
36
-
-
24944547482
-
Tensional homeostasis and the malignant phenotype
-
Paszek M.J., Zahir N., Johnson K.R., Lakins J.N., Rozenberg G.I., Gefen A., Reinhart-King C.A., Margulies S.S., Dembo M., Boettiger D., et al. Tensional homeostasis and the malignant phenotype. Cancer Cell 2005, 8:241-254.
-
(2005)
Cancer Cell
, vol.8
, pp. 241-254
-
-
Paszek, M.J.1
Zahir, N.2
Johnson, K.R.3
Lakins, J.N.4
Rozenberg, G.I.5
Gefen, A.6
Reinhart-King, C.A.7
Margulies, S.S.8
Dembo, M.9
Boettiger, D.10
-
37
-
-
70450222098
-
Matrix crosslinking forces tumor progression by enhancing integrin signaling
-
Levental K.R., Yu H., Kass L., Lakins J.N., Egeblad M., Erler J.T., Fong S.F., Csiszar K., Giaccia A., Weninger W., et al. Matrix crosslinking forces tumor progression by enhancing integrin signaling. Cell 2009, 139:891-906.
-
(2009)
Cell
, vol.139
, pp. 891-906
-
-
Levental, K.R.1
Yu, H.2
Kass, L.3
Lakins, J.N.4
Egeblad, M.5
Erler, J.T.6
Fong, S.F.7
Csiszar, K.8
Giaccia, A.9
Weninger, W.10
-
38
-
-
34447309766
-
The myofibroblast: one function, multiple origins
-
Hinz B., Phan S.H., Thannickal V.J., Galli A., Bochaton-Piallat M.L., Gabbiani G. The myofibroblast: one function, multiple origins. Am J Pathol 2007, 170:1807-1816.
-
(2007)
Am J Pathol
, vol.170
, pp. 1807-1816
-
-
Hinz, B.1
Phan, S.H.2
Thannickal, V.J.3
Galli, A.4
Bochaton-Piallat, M.L.5
Gabbiani, G.6
-
39
-
-
37249044357
-
Myofibroblast contraction activates latent TGF-beta1 from the extracellular matrix
-
Wipff P.J., Rifkin D.B., Meister J.J., Hinz B. Myofibroblast contraction activates latent TGF-beta1 from the extracellular matrix. J Cell Biol 2007, 179:1311-1323.
-
(2007)
J Cell Biol
, vol.179
, pp. 1311-1323
-
-
Wipff, P.J.1
Rifkin, D.B.2
Meister, J.J.3
Hinz, B.4
-
40
-
-
33846782878
-
Collagen reorganization at the tumor-stromal interface facilitates local invasion
-
Provenzano P.P., Eliceiri K.W., Campbell J.M., Inman D.R., White J.G., Keely P.J. Collagen reorganization at the tumor-stromal interface facilitates local invasion. BMC Med 2006, 4:38.
-
(2006)
BMC Med
, vol.4
, pp. 38
-
-
Provenzano, P.P.1
Eliceiri, K.W.2
Campbell, J.M.3
Inman, D.R.4
White, J.G.5
Keely, P.J.6
-
41
-
-
34047246527
-
Direct visualization of macrophage-assisted tumor cell intravasation in mammary tumors
-
Wyckoff J.B., Wang Y., Lin E.Y., Li J.F., Goswami S., Stanley E.R., Segall J.E., Pollard J.W., Condeelis J. Direct visualization of macrophage-assisted tumor cell intravasation in mammary tumors. Cancer Res 2007, 67:2649-2656.
-
(2007)
Cancer Res
, vol.67
, pp. 2649-2656
-
-
Wyckoff, J.B.1
Wang, Y.2
Lin, E.Y.3
Li, J.F.4
Goswami, S.5
Stanley, E.R.6
Segall, J.E.7
Pollard, J.W.8
Condeelis, J.9
-
42
-
-
36749013537
-
Fibroblast-led collective invasion of carcinoma cells with differing roles for RhoGTPases in leading and following cells
-
Gaggioli C., Hooper S., Hidalgo-Carcedo C., Grosse R., Marshall J.F., Harrington K., Sahai E. Fibroblast-led collective invasion of carcinoma cells with differing roles for RhoGTPases in leading and following cells. Nat Cell Biol 2007, 9:1392-1400.
-
(2007)
Nat Cell Biol
, vol.9
, pp. 1392-1400
-
-
Gaggioli, C.1
Hooper, S.2
Hidalgo-Carcedo, C.3
Grosse, R.4
Marshall, J.F.5
Harrington, K.6
Sahai, E.7
-
43
-
-
0036512208
-
New functions for the matrix metalloproteinases in cancer progression
-
Egeblad M., Werb Z. New functions for the matrix metalloproteinases in cancer progression. Nat Rev Cancer 2002, 2:161-174.
-
(2002)
Nat Rev Cancer
, vol.2
, pp. 161-174
-
-
Egeblad, M.1
Werb, Z.2
-
44
-
-
33847133438
-
Fibroblast-derived MT1-MMP promotes tumor progression in vitro and in vivo
-
Zhang W., Matrisian L.M., Holmbeck K., Vick C.C., Rosenthal E.L. Fibroblast-derived MT1-MMP promotes tumor progression in vitro and in vivo. BMC Cancer 2006, 6:52.
-
(2006)
BMC Cancer
, vol.6
, pp. 52
-
-
Zhang, W.1
Matrisian, L.M.2
Holmbeck, K.3
Vick, C.C.4
Rosenthal, E.L.5
-
45
-
-
77950950894
-
Macrophage diversity enhances tumor progression and metastasis
-
Qian B.Z., Pollard J.W. Macrophage diversity enhances tumor progression and metastasis. Cell 2011, 141:39-51.
-
(2011)
Cell
, vol.141
, pp. 39-51
-
-
Qian, B.Z.1
Pollard, J.W.2
-
46
-
-
0035815750
-
Authentic matrix vesicles contain active metalloproteases (MMP). a role for matrix vesicle-associated MMP-13 in activation of transforming growth factor-beta
-
D'Angelo M., Billings P.C., Pacifici M., Leboy P.S., Kirsch T. Authentic matrix vesicles contain active metalloproteases (MMP). a role for matrix vesicle-associated MMP-13 in activation of transforming growth factor-beta. J Biol Chem 2001, 276:11347-11353.
-
(2001)
J Biol Chem
, vol.276
, pp. 11347-11353
-
-
D'Angelo, M.1
Billings, P.C.2
Pacifici, M.3
Leboy, P.S.4
Kirsch, T.5
-
47
-
-
34948853273
-
A role for endothelial-derived matrix metalloproteinase-2 in breast cancer cell transmigration across the endothelial-basement membrane barrier
-
Kargozaran H., Yuan S.Y., Breslin J.W., Watson K.D., Gaudreault N., Breen A., Wu M.H. A role for endothelial-derived matrix metalloproteinase-2 in breast cancer cell transmigration across the endothelial-basement membrane barrier. Clin Exp Metastasis 2007, 24:495-502.
-
(2007)
Clin Exp Metastasis
, vol.24
, pp. 495-502
-
-
Kargozaran, H.1
Yuan, S.Y.2
Breslin, J.W.3
Watson, K.D.4
Gaudreault, N.5
Breen, A.6
Wu, M.H.7
-
48
-
-
78649883292
-
Competition amongst Eph receptors regulates contact inhibition of locomotion and invasiveness in prostate cancer cells
-
Astin J.W., Batson J., Kadir S., Charlet J., Persad R.A., Gillatt D., Oxley J.D., Nobes C.D. Competition amongst Eph receptors regulates contact inhibition of locomotion and invasiveness in prostate cancer cells. Nat Cell Biol 2010, 12:1194-1204.
-
(2010)
Nat Cell Biol
, vol.12
, pp. 1194-1204
-
-
Astin, J.W.1
Batson, J.2
Kadir, S.3
Charlet, J.4
Persad, R.A.5
Gillatt, D.6
Oxley, J.D.7
Nobes, C.D.8
-
49
-
-
0033376770
-
Cell adhesion molecules in the development and progression of malignant melanoma
-
Johnson J.P. Cell adhesion molecules in the development and progression of malignant melanoma. Cancer Metastasis Rev 1999, 18:345-357.
-
(1999)
Cancer Metastasis Rev
, vol.18
, pp. 345-357
-
-
Johnson, J.P.1
-
50
-
-
0029670681
-
Identification of alpha v beta 3 as a heterotypic ligand for CD31/PECAM-1
-
Buckley C.D., Doyonnas R., Newton J.P., Blystone S.D., Brown E.J., Watt S.M., Simmons D.L. Identification of alpha v beta 3 as a heterotypic ligand for CD31/PECAM-1. J Cell Sci 1996, 109(Pt 2):437-445.
-
(1996)
J Cell Sci
, vol.109
, Issue.PART 2
, pp. 437-445
-
-
Buckley, C.D.1
Doyonnas, R.2
Newton, J.P.3
Blystone, S.D.4
Brown, E.J.5
Watt, S.M.6
Simmons, D.L.7
-
51
-
-
0030065691
-
Human neural cell adhesion molecule L1 and rat homologue NILE are ligands for integrin alpha v beta 3
-
Montgomery A.M., Becker J.C., Siu C.H., Lemmon V.P., Cheresh D.A., Pancook J.D., Zhao X., Reisfeld R.A. Human neural cell adhesion molecule L1 and rat homologue NILE are ligands for integrin alpha v beta 3. J Cell Biol 1996, 132:475-485.
-
(1996)
J Cell Biol
, vol.132
, pp. 475-485
-
-
Montgomery, A.M.1
Becker, J.C.2
Siu, C.H.3
Lemmon, V.P.4
Cheresh, D.A.5
Pancook, J.D.6
Zhao, X.7
Reisfeld, R.A.8
-
52
-
-
79751472667
-
Tumor-derived JAGGED1 promotes osteolytic bone metastasis of breast cancer by engaging notch signaling in bone cells
-
Sethi N., Dai X., Winter C.G., Kang Y. Tumor-derived JAGGED1 promotes osteolytic bone metastasis of breast cancer by engaging notch signaling in bone cells. Cancer Cell 2011, 19:192-205.
-
(2011)
Cancer Cell
, vol.19
, pp. 192-205
-
-
Sethi, N.1
Dai, X.2
Winter, C.G.3
Kang, Y.4
-
53
-
-
78650050458
-
Endothelial cells as key determinants of the tumor microenvironment: interaction with tumor cells, extracellular matrix and immune killer cells
-
Chouaib S., Kieda C., Benlalam H., Noman M.Z., Mami-Chouaib F., Ruegg C. Endothelial cells as key determinants of the tumor microenvironment: interaction with tumor cells, extracellular matrix and immune killer cells. Crit Rev Immunol 2010, 30:529-545.
-
(2010)
Crit Rev Immunol
, vol.30
, pp. 529-545
-
-
Chouaib, S.1
Kieda, C.2
Benlalam, H.3
Noman, M.Z.4
Mami-Chouaib, F.5
Ruegg, C.6
-
55
-
-
0037478437
-
Hypoxia promotes invasive growth by transcriptional activation of the met protooncogene
-
Pennacchietti S., Michieli P., Galluzzo M., Mazzone M., Giordano S., Comoglio P.M. Hypoxia promotes invasive growth by transcriptional activation of the met protooncogene. Cancer Cell 2003, 3:347-361.
-
(2003)
Cancer Cell
, vol.3
, pp. 347-361
-
-
Pennacchietti, S.1
Michieli, P.2
Galluzzo, M.3
Mazzone, M.4
Giordano, S.5
Comoglio, P.M.6
-
56
-
-
37349079197
-
Systemic spread is an early step in breast cancer
-
Husemann Y., Geigl J.B., Schubert F., Musiani P., Meyer M., Burghart E., Forni G., Eils R., Fehm T., Riethmuller G., et al. Systemic spread is an early step in breast cancer. Cancer Cell 2008, 13:58-68.
-
(2008)
Cancer Cell
, vol.13
, pp. 58-68
-
-
Husemann, Y.1
Geigl, J.B.2
Schubert, F.3
Musiani, P.4
Meyer, M.5
Burghart, E.6
Forni, G.7
Eils, R.8
Fehm, T.9
Riethmuller, G.10
-
57
-
-
63049104211
-
Microenvironmental regulation of metastasis
-
Joyce J.A., Pollard J.W. Microenvironmental regulation of metastasis. Nat Rev Cancer 2009, 9:239-252.
-
(2009)
Nat Rev Cancer
, vol.9
, pp. 239-252
-
-
Joyce, J.A.1
Pollard, J.W.2
-
58
-
-
70450198396
-
Epithelial-mesenchymal transitions in development and disease
-
Thiery J.P., Acloque H., Huang R.Y., Nieto M.A. Epithelial-mesenchymal transitions in development and disease. Cell 2009, 139:871-890.
-
(2009)
Cell
, vol.139
, pp. 871-890
-
-
Thiery, J.P.1
Acloque, H.2
Huang, R.Y.3
Nieto, M.A.4
-
59
-
-
2442649165
-
Enhanced tenascin-C expression and matrix deposition during Ras/TGF-beta-induced progression of mammary tumor cells
-
Maschler S., Grunert S., Danielopol A., Beug H., Wirl G. Enhanced tenascin-C expression and matrix deposition during Ras/TGF-beta-induced progression of mammary tumor cells. Oncogene 2004, 23:3622-3633.
-
(2004)
Oncogene
, vol.23
, pp. 3622-3633
-
-
Maschler, S.1
Grunert, S.2
Danielopol, A.3
Beug, H.4
Wirl, G.5
-
60
-
-
58649092605
-
Matricellular proteins produced by melanocytes and melanomas: in search for functions
-
Fukunaga-Kalabis M., Santiago-Walker A., Herlyn M. Matricellular proteins produced by melanocytes and melanomas: in search for functions. Cancer Microenviron 2008, 1:93-102.
-
(2008)
Cancer Microenviron
, vol.1
, pp. 93-102
-
-
Fukunaga-Kalabis, M.1
Santiago-Walker, A.2
Herlyn, M.3
-
61
-
-
38049115129
-
Endogenous human microRNAs that suppress breast cancer metastasis
-
Tavazoie S.F., Alarcon C., Oskarsson T., Padua D., Wang Q., Bos P.D., Gerald W.L., Massague J. Endogenous human microRNAs that suppress breast cancer metastasis. Nature 2008, 451:147-152.
-
(2008)
Nature
, vol.451
, pp. 147-152
-
-
Tavazoie, S.F.1
Alarcon, C.2
Oskarsson, T.3
Padua, D.4
Wang, Q.5
Bos, P.D.6
Gerald, W.L.7
Massague, J.8
-
62
-
-
28644432204
-
VEGFR1-positive haematopoietic bone marrow progenitors initiate the pre-metastatic niche
-
Kaplan R.N., Riba R.D., Zacharoulis S., Bramley A.H., Vincent L., Costa C., MacDonald D.D., Jin D.K., Shido K., Kerns S.A., et al. VEGFR1-positive haematopoietic bone marrow progenitors initiate the pre-metastatic niche. Nature 2005, 438:820-827.
-
(2005)
Nature
, vol.438
, pp. 820-827
-
-
Kaplan, R.N.1
Riba, R.D.2
Zacharoulis, S.3
Bramley, A.H.4
Vincent, L.5
Costa, C.6
MacDonald, D.D.7
Jin, D.K.8
Shido, K.9
Kerns, S.A.10
-
63
-
-
0036674501
-
Dissemination and growth of cancer cells in metastatic sites
-
Chambers A.F., Groom A.C., MacDonald I.C. Dissemination and growth of cancer cells in metastatic sites. Nat Rev Cancer 2002, 2:563-572.
-
(2002)
Nat Rev Cancer
, vol.2
, pp. 563-572
-
-
Chambers, A.F.1
Groom, A.C.2
MacDonald, I.C.3
-
64
-
-
0035158462
-
Involvement of integrin alpha(v)beta(3) and cell adhesion molecule L1 in transendothelial migration of melanoma cells
-
Voura E.B., Ramjeesingh R.A., Montgomery A.M., Siu C.H. Involvement of integrin alpha(v)beta(3) and cell adhesion molecule L1 in transendothelial migration of melanoma cells. Mol Biol Cell 2001, 12:2699-2710.
-
(2001)
Mol Biol Cell
, vol.12
, pp. 2699-2710
-
-
Voura, E.B.1
Ramjeesingh, R.A.2
Montgomery, A.M.3
Siu, C.H.4
-
65
-
-
0030728116
-
Role of cadherins in the transendothelial migration of melanoma cells in culture
-
Sandig M., Voura E.B., Kalnins V.I., Siu C.H. Role of cadherins in the transendothelial migration of melanoma cells in culture. Cell Motil Cytoskeleton 1997, 38:351-364.
-
(1997)
Cell Motil Cytoskeleton
, vol.38
, pp. 351-364
-
-
Sandig, M.1
Voura, E.B.2
Kalnins, V.I.3
Siu, C.H.4
-
66
-
-
41149178781
-
The tumor cell-host organ interface in the early onset of metastatic organ colonisation
-
Gassmann P., Haier J. The tumor cell-host organ interface in the early onset of metastatic organ colonisation. Clin Exp Metastasis 2008, 25:171-181.
-
(2008)
Clin Exp Metastasis
, vol.25
, pp. 171-181
-
-
Gassmann, P.1
Haier, J.2
-
67
-
-
68749109536
-
A distinct macrophage population mediates metastatic breast cancer cell extravasation, establishment and growth
-
Qian B., Deng Y., Im J.H., Muschel R.J., Zou Y., Li J., Lang R.A., Pollard J.W. A distinct macrophage population mediates metastatic breast cancer cell extravasation, establishment and growth. PLoS One 2009, 4:e6562.
-
(2009)
PLoS One
, vol.4
-
-
Qian, B.1
Deng, Y.2
Im, J.H.3
Muschel, R.J.4
Zou, Y.5
Li, J.6
Lang, R.A.7
Pollard, J.W.8
-
68
-
-
0038488950
-
A multigenic program mediating breast cancer metastasis to bone
-
Kang Y., Siegel P.M., Shu W., Drobnjak M., Kakonen S.M., Cordon-Cardo C., Guise T.A., Massague J. A multigenic program mediating breast cancer metastasis to bone. Cancer Cell 2003, 3:537-549.
-
(2003)
Cancer Cell
, vol.3
, pp. 537-549
-
-
Kang, Y.1
Siegel, P.M.2
Shu, W.3
Drobnjak, M.4
Kakonen, S.M.5
Cordon-Cardo, C.6
Guise, T.A.7
Massague, J.8
-
69
-
-
33845811455
-
Preparing the "soil": the premetastatic niche
-
Kaplan R.N., Rafii S., Lyden D. Preparing the "soil": the premetastatic niche. Cancer Res 2006, 66:11089-11093.
-
(2006)
Cancer Res
, vol.66
, pp. 11089-11093
-
-
Kaplan, R.N.1
Rafii, S.2
Lyden, D.3
-
70
-
-
0036782035
-
MMP9 induction by vascular endothelial growth factor receptor-1 is involved in lung-specific metastasis
-
Hiratsuka S., Nakamura K., Iwai S., Murakami M., Itoh T., Kijima H., Shipley J.M., Senior R.M., Shibuya M. MMP9 induction by vascular endothelial growth factor receptor-1 is involved in lung-specific metastasis. Cancer Cell 2002, 2:289-300.
-
(2002)
Cancer Cell
, vol.2
, pp. 289-300
-
-
Hiratsuka, S.1
Nakamura, K.2
Iwai, S.3
Murakami, M.4
Itoh, T.5
Kijima, H.6
Shipley, J.M.7
Senior, R.M.8
Shibuya, M.9
-
71
-
-
57849100048
-
Hypoxia-induced lysyl oxidase is a critical mediator of bone marrow cell recruitment to form the premetastatic niche
-
Erler J.T., Bennewith K.L., Cox T.R., Lang G., Bird D., Koong A., Le Q.T., Giaccia A.J. Hypoxia-induced lysyl oxidase is a critical mediator of bone marrow cell recruitment to form the premetastatic niche. Cancer Cell 2009, 15:35-44.
-
(2009)
Cancer Cell
, vol.15
, pp. 35-44
-
-
Erler, J.T.1
Bennewith, K.L.2
Cox, T.R.3
Lang, G.4
Bird, D.5
Koong, A.6
Le, Q.T.7
Giaccia, A.J.8
-
72
-
-
33751504690
-
Tumour-mediated upregulation of chemoattractants and recruitment of myeloid cells predetermines lung metastasis
-
Hiratsuka S., Watanabe A., Aburatani H., Maru Y. Tumour-mediated upregulation of chemoattractants and recruitment of myeloid cells predetermines lung metastasis. Nat Cell Biol 2006, 8:1369-1375.
-
(2006)
Nat Cell Biol
, vol.8
, pp. 1369-1375
-
-
Hiratsuka, S.1
Watanabe, A.2
Aburatani, H.3
Maru, Y.4
-
73
-
-
55549128598
-
The S100A8-serum amyloid A3-TLR4 paracrine cascade establishes a pre-metastatic phase
-
Hiratsuka S., Watanabe A., Sakurai Y., Akashi-Takamura S., Ishibashi S., Miyake K., Shibuya M., Akira S., Aburatani H., Maru Y. The S100A8-serum amyloid A3-TLR4 paracrine cascade establishes a pre-metastatic phase. Nat Cell Biol 2008, 10:1349-1355.
-
(2008)
Nat Cell Biol
, vol.10
, pp. 1349-1355
-
-
Hiratsuka, S.1
Watanabe, A.2
Sakurai, Y.3
Akashi-Takamura, S.4
Ishibashi, S.5
Miyake, K.6
Shibuya, M.7
Akira, S.8
Aburatani, H.9
Maru, Y.10
-
74
-
-
0033032317
-
Extracellular matrix proteins protect small cell lung cancer cells against apoptosis: a mechanism for small cell lung cancer growth and drug resistance in vivo
-
Sethi T., Rintoul R.C., Moore S.M., MacKinnon A.C., Salter D., Choo C., Chilvers E.R., Dransfield I., Donnelly S.C., Strieter R., et al. Extracellular matrix proteins protect small cell lung cancer cells against apoptosis: a mechanism for small cell lung cancer growth and drug resistance in vivo. Nat Med 1999, 5:662-668.
-
(1999)
Nat Med
, vol.5
, pp. 662-668
-
-
Sethi, T.1
Rintoul, R.C.2
Moore, S.M.3
MacKinnon, A.C.4
Salter, D.5
Choo, C.6
Chilvers, E.R.7
Dransfield, I.8
Donnelly, S.C.9
Strieter, R.10
-
75
-
-
57849106330
-
PDGF-C mediates the angiogenic and tumorigenic properties of fibroblasts associated with tumors refractory to anti-VEGF treatment
-
Crawford Y., Kasman I., Yu L., Zhong C., Wu X., Modrusan Z., Kaminker J., Ferrara N. PDGF-C mediates the angiogenic and tumorigenic properties of fibroblasts associated with tumors refractory to anti-VEGF treatment. Cancer Cell 2009, 15:21-34.
-
(2009)
Cancer Cell
, vol.15
, pp. 21-34
-
-
Crawford, Y.1
Kasman, I.2
Yu, L.3
Zhong, C.4
Wu, X.5
Modrusan, Z.6
Kaminker, J.7
Ferrara, N.8
-
76
-
-
0034193258
-
Role of extracellular matrix assembly in interstitial transport in solid tumors
-
Netti P.A., Berk D.A., Swartz M.A., Grodzinsky A.J., Jain R.K. Role of extracellular matrix assembly in interstitial transport in solid tumors. Cancer Res 2000, 60:2497-2503.
-
(2000)
Cancer Res
, vol.60
, pp. 2497-2503
-
-
Netti, P.A.1
Berk, D.A.2
Swartz, M.A.3
Grodzinsky, A.J.4
Jain, R.K.5
-
77
-
-
33645066093
-
Degradation of fibrillar collagen in a human melanoma xenograft improves the efficacy of an oncolytic herpes simplex virus vector
-
McKee T.D., Grandi P., Mok W., Alexandrakis G., Insin N., Zimmer J.P., Bawendi M.G., Boucher Y., Breakefield X.O., Jain R.K. Degradation of fibrillar collagen in a human melanoma xenograft improves the efficacy of an oncolytic herpes simplex virus vector. Cancer Res 2006, 66:2509-2513.
-
(2006)
Cancer Res
, vol.66
, pp. 2509-2513
-
-
McKee, T.D.1
Grandi, P.2
Mok, W.3
Alexandrakis, G.4
Insin, N.5
Zimmer, J.P.6
Bawendi, M.G.7
Boucher, Y.8
Breakefield, X.O.9
Jain, R.K.10
-
79
-
-
40449105940
-
Equilibrium between host and cancer caused by effector T cells killing tumor stroma
-
Zhang B., Zhang Y., Bowerman N.A., Schietinger A., Fu Y.X., Kranz D.M., Rowley D.A., Schreiber H. Equilibrium between host and cancer caused by effector T cells killing tumor stroma. Cancer Res 2008, 68:1563-1571.
-
(2008)
Cancer Res
, vol.68
, pp. 1563-1571
-
-
Zhang, B.1
Zhang, Y.2
Bowerman, N.A.3
Schietinger, A.4
Fu, Y.X.5
Kranz, D.M.6
Rowley, D.A.7
Schreiber, H.8
-
80
-
-
33745837774
-
Targeting tumor-associated fibroblasts improves cancer chemotherapy by increasing intratumoral drug uptake
-
Loeffler M., Kruger J.A., Niethammer A.G., Reisfeld R.A. Targeting tumor-associated fibroblasts improves cancer chemotherapy by increasing intratumoral drug uptake. J Clin Invest 2006, 116:1955-1962.
-
(2006)
J Clin Invest
, vol.116
, pp. 1955-1962
-
-
Loeffler, M.1
Kruger, J.A.2
Niethammer, A.G.3
Reisfeld, R.A.4
-
81
-
-
38849202330
-
Functions of paracrine PDGF signaling in the proangiogenic tumor stroma revealed by pharmacological targeting
-
Pietras K., Pahler J., Bergers G., Hanahan D. Functions of paracrine PDGF signaling in the proangiogenic tumor stroma revealed by pharmacological targeting. PLoS Med 2008, 5:e19.
-
(2008)
PLoS Med
, vol.5
-
-
Pietras, K.1
Pahler, J.2
Bergers, G.3
Hanahan, D.4
-
82
-
-
67149143399
-
Inhibition of Hedgehog signaling enhances delivery of chemotherapy in a mouse model of pancreatic cancer
-
Olive K.P., Jacobetz M.A., Davidson C.J., Gopinathan A., McIntyre D., Honess D., Madhu B., Goldgraben M.A., Caldwell M.E., Allard D., et al. Inhibition of Hedgehog signaling enhances delivery of chemotherapy in a mouse model of pancreatic cancer. Science 2009, 324:1457-1461.
-
(2009)
Science
, vol.324
, pp. 1457-1461
-
-
Olive, K.P.1
Jacobetz, M.A.2
Davidson, C.J.3
Gopinathan, A.4
McIntyre, D.5
Honess, D.6
Madhu, B.7
Goldgraben, M.A.8
Caldwell, M.E.9
Allard, D.10
-
83
-
-
33845767868
-
Macrophages regulate the angiogenic switch in a mouse model of breast cancer
-
Lin E.Y., Li J.F., Gnatovskiy L., Deng Y., Zhu L., Grzesik D.A., Qian H., Xue X.N., Pollard J.W. Macrophages regulate the angiogenic switch in a mouse model of breast cancer. Cancer Res 2006, 66:11238-11246.
-
(2006)
Cancer Res
, vol.66
, pp. 11238-11246
-
-
Lin, E.Y.1
Li, J.F.2
Gnatovskiy, L.3
Deng, Y.4
Zhu, L.5
Grzesik, D.A.6
Qian, H.7
Xue, X.N.8
Pollard, J.W.9
-
84
-
-
26644471951
-
Drug resistance by evasion of antiangiogenic targeting of VEGF signaling in late-stage pancreatic islet tumors
-
Casanovas O., Hicklin D.J., Bergers G., Hanahan D. Drug resistance by evasion of antiangiogenic targeting of VEGF signaling in late-stage pancreatic islet tumors. Cancer Cell 2005, 8:299-309.
-
(2005)
Cancer Cell
, vol.8
, pp. 299-309
-
-
Casanovas, O.1
Hicklin, D.J.2
Bergers, G.3
Hanahan, D.4
-
85
-
-
60649106195
-
Antiangiogenic therapy elicits malignant progression of tumors to increased local invasion and distant metastasis
-
Paez-Ribes M., Allen E., Hudock J., Takeda T., Okuyama H., Vinals F., Inoue M., Bergers G., Hanahan D., Casanovas O. Antiangiogenic therapy elicits malignant progression of tumors to increased local invasion and distant metastasis. Cancer Cell 2009, 15:220-231.
-
(2009)
Cancer Cell
, vol.15
, pp. 220-231
-
-
Paez-Ribes, M.1
Allen, E.2
Hudock, J.3
Takeda, T.4
Okuyama, H.5
Vinals, F.6
Inoue, M.7
Bergers, G.8
Hanahan, D.9
Casanovas, O.10
-
86
-
-
77951667987
-
Mechanisms of resistance to antiangiogenesis therapy
-
Azam F., Mehta S., Harris A.L. Mechanisms of resistance to antiangiogenesis therapy. Eur J Cancer 2010, 46:1323-1332.
-
(2010)
Eur J Cancer
, vol.46
, pp. 1323-1332
-
-
Azam, F.1
Mehta, S.2
Harris, A.L.3
|