-
1
-
-
0035066332
-
Alzheimer's disease: genes, proteins, and therapy
-
Selkoe DJ. Alzheimer's disease: genes, proteins, and therapy. Physiol Rev 2001; 81: 741-766.
-
(2001)
Physiol Rev
, vol.81
, pp. 741-766
-
-
Selkoe, D.J.1
-
2
-
-
3943092621
-
Pathways towards and away from Alzheimer's disease
-
Mattson MP. Pathways towards and away from Alzheimer's disease. Nature 2004; 430: 631-639.
-
(2004)
Nature
, vol.430
, pp. 631-639
-
-
Mattson, M.P.1
-
3
-
-
34250819839
-
Intracellular amyloid-beta in Alzheimer's disease
-
LaFerla FM, Green KN, Oddo S. Intracellular amyloid-beta in Alzheimer's disease. Nat Rev Neurosci 2007; 8: 499-509.
-
(2007)
Nat Rev Neurosci
, vol.8
, pp. 499-509
-
-
LaFerla, F.M.1
Green, K.N.2
Oddo, S.3
-
4
-
-
39149122810
-
Amyloid beta, mitochondrial dysfunction and synaptic damage: implications for cognitive decline in aging and Alzheimer's disease
-
Reddy PH, Beal MF. Amyloid beta, mitochondrial dysfunction and synaptic damage: implications for cognitive decline in aging and Alzheimer's disease. Trends Mol Med 2008; 14: 45-53.
-
(2008)
Trends Mol Med
, vol.14
, pp. 45-53
-
-
Reddy, P.H.1
Beal, M.F.2
-
5
-
-
12944259210
-
Cerebral metabolic and cognitive decline in persons at genetic risk for Alzheimer's disease
-
Small GW, Ercoli LM, Silverman DH etal. Cerebral metabolic and cognitive decline in persons at genetic risk for Alzheimer's disease. Proc Natl Acad Sci U S A 2000; 97: 6037-6042.
-
(2000)
Proc Natl Acad Sci U S A
, vol.97
, pp. 6037-6042
-
-
Small, G.W.1
Ercoli, L.M.2
Silverman, D.H.3
-
6
-
-
0035845499
-
Prediction of cognitive decline in normal elderly subjects with 2-[(18)F]fluoro-2-deoxy-D-glucose/poitron-emission tomography (FDG/PET)
-
DeLeon MJ, Convit A, Wolf OT etal. Prediction of cognitive decline in normal elderly subjects with 2-[(18)F]fluoro-2-deoxy-D-glucose/poitron-emission tomography (FDG/PET). Proc Natl Acad Sci U S A 2001; 98: 10966-10971.
-
(2001)
Proc Natl Acad Sci U S A
, vol.98
, pp. 10966-10971
-
-
DeLeon, M.J.1
Convit, A.2
Wolf, O.T.3
-
7
-
-
0035853154
-
Declining brain activity in cognitively normal apolipoprotein E epsilon 4 heterozygotes: a foundation for using positron emission tomography to efficiently test treatments to prevent Alzheimer's disease
-
Reiman EM, Caselli RJ, Chen K, Alexander GE, Bandy D, Frost J. Declining brain activity in cognitively normal apolipoprotein E epsilon 4 heterozygotes: a foundation for using positron emission tomography to efficiently test treatments to prevent Alzheimer's disease. Proc Natl Acad Sci U S A 2001; 98: 3334-3339.
-
(2001)
Proc Natl Acad Sci U S A
, vol.98
, pp. 3334-3339
-
-
Reiman, E.M.1
Caselli, R.J.2
Chen, K.3
Alexander, G.E.4
Bandy, D.5
Frost, J.6
-
8
-
-
38149006292
-
Hippocampal hypometabolism predicts cognitive decline from normal aging
-
Mosconi L, DeSanti S, Li J etal. Hippocampal hypometabolism predicts cognitive decline from normal aging. Neurobiol Aging 2008; 29: 676-692.
-
(2008)
Neurobiol Aging
, vol.29
, pp. 676-692
-
-
Mosconi, L.1
DeSanti, S.2
Li, J.3
-
9
-
-
0032983691
-
Activities of key glycolytic enzymes in the brains of patients with Alzheimer's disease
-
Bigl M, Brückner MK, Arendt T, Bigl V, Eschrich K. Activities of key glycolytic enzymes in the brains of patients with Alzheimer's disease. J Neural Transm 1999; 106: 499-511.
-
(1999)
J Neural Transm
, vol.106
, pp. 499-511
-
-
Bigl, M.1
Brückner, M.K.2
Arendt, T.3
Bigl, V.4
Eschrich, K.5
-
10
-
-
0034864615
-
Amyloid β-peptide inhibits neuronal glucose uptake by preventing exocytosis
-
Uemura E, Greenlee HW. Amyloid β-peptide inhibits neuronal glucose uptake by preventing exocytosis. Exp Neurol 2001; 170: 270-276.
-
(2001)
Exp Neurol
, vol.170
, pp. 270-276
-
-
Uemura, E.1
Greenlee, H.W.2
-
11
-
-
0036218260
-
Amyloid β-peptide decreases neuronal glucose uptake despite causing increase in GLUT3 mRNA transcription and GLUT3 translocation to the plasma membrane
-
Prapong T, Buss J, Hsu WH, Heine P, Greenlee HW, Uemura E. Amyloid β-peptide decreases neuronal glucose uptake despite causing increase in GLUT3 mRNA transcription and GLUT3 translocation to the plasma membrane. Exp Neurol 2002; 174: 253-258.
-
(2002)
Exp Neurol
, vol.174
, pp. 253-258
-
-
Prapong, T.1
Buss, J.2
Hsu, W.H.3
Heine, P.4
Greenlee, H.W.5
Uemura, E.6
-
13
-
-
0037041426
-
Naturally secreted oligomers of amyloid β protein potently inhibit hippocampal long-term potentiation in vivo
-
Walsh DM, Klyubin I, Fadeeva JV etal. Naturally secreted oligomers of amyloid β protein potently inhibit hippocampal long-term potentiation in vivo. Nature 2002; 418: 535-539.
-
(2002)
Nature
, vol.418
, pp. 535-539
-
-
Walsh, D.M.1
Klyubin, I.2
Fadeeva, J.V.3
-
14
-
-
0037200117
-
Oligomeric and fibrillar species of amyloid-β peptides differentially affect neuronal viability
-
Dahlgren KN, Manelli AM, Stine WB Jr, Baker LK, Krafft GA, LaDu MJ. Oligomeric and fibrillar species of amyloid-β peptides differentially affect neuronal viability. J Biol Chem 2002; 277: 32046-32053.
-
(2002)
J Biol Chem
, vol.277
, pp. 32046-32053
-
-
Dahlgren, K.N.1
Manelli, A.M.2
Stine Jr, W.B.3
Baker, L.K.4
Krafft, G.A.5
LaDu, M.J.6
-
15
-
-
29044449855
-
Risk of dementia in diabetes mellitus: a systematic review
-
Biessels GJ, Staekenborg S, Brunner E, Brayne C, Scheltens P. Risk of dementia in diabetes mellitus: a systematic review. Lancet Neurol 2006; 5: 64-74.
-
(2006)
Lancet Neurol
, vol.5
, pp. 64-74
-
-
Biessels, G.J.1
Staekenborg, S.2
Brunner, E.3
Brayne, C.4
Scheltens, P.5
-
16
-
-
33748698462
-
Association of metabolic syndrome with Alzheimer disease: a population-based study
-
Vanhanen M, Koivisto K, Moilanen L etal. Association of metabolic syndrome with Alzheimer disease: a population-based study. Neurology 2006; 67: 843-847.
-
(2006)
Neurology
, vol.67
, pp. 843-847
-
-
Vanhanen, M.1
Koivisto, K.2
Moilanen, L.3
-
17
-
-
34147178368
-
The epidemiology of adiposity and dementia
-
Whitmer RA. The epidemiology of adiposity and dementia. Curr Alzheimer Res 2007; 4: 117-122.
-
(2007)
Curr Alzheimer Res
, vol.4
, pp. 117-122
-
-
Whitmer, R.A.1
-
18
-
-
38049110692
-
Amyloid beta oligomers induce impairment of neuronal insulin receptors
-
Zhao WQ, DeFelice FG, Fernandez S etal. Amyloid beta oligomers induce impairment of neuronal insulin receptors. FASEB J 2008; 22: 246-260.
-
(2008)
FASEB J
, vol.22
, pp. 246-260
-
-
Zhao, W.Q.1
DeFelice, F.G.2
Fernandez, S.3
-
19
-
-
30644475475
-
1-40 induces NMDA-dependent degradation of postsynaptic density-95 at glutamatergic synapses
-
1-40 induces NMDA-dependent degradation of postsynaptic density-95 at glutamatergic synapses. J Neurosci 2005; 25: 11061-11070.
-
(2005)
J Neurosci
, vol.25
, pp. 11061-11070
-
-
Roselli, F.1
Tirard, M.2
Lu, J.3
-
20
-
-
20044370990
-
Curcumin inhibits formation of amyloid β oligomers and fibrils, binds plaques, and reduces amyloid in vivo
-
Fusheng Y, Giselle PL, Aynun NB etal. Curcumin inhibits formation of amyloid β oligomers and fibrils, binds plaques, and reduces amyloid in vivo. J Biol Chem 2005; 280: 5892-5901.
-
(2005)
J Biol Chem
, vol.280
, pp. 5892-5901
-
-
Fusheng, Y.1
Giselle, P.L.2
Aynun, N.B.3
-
21
-
-
0027226219
-
Optimized survival of hippocampal neurons in B27-supplemented Neurobasal, a new serum free medium combination
-
Brewer GJ, Torricelli JR, Evege EK, Price PJ. Optimized survival of hippocampal neurons in B27-supplemented Neurobasal, a new serum free medium combination. J Neurosci Res 1993; 35: 567-576.
-
(1993)
J Neurosci Res
, vol.35
, pp. 567-576
-
-
Brewer, G.J.1
Torricelli, J.R.2
Evege, E.K.3
Price, P.J.4
-
22
-
-
33644943399
-
A nonradioisotope, enzymatic assay for 2-deoxyglucose uptake in L6 skeletal muscle cells cultured in a 96-well microplate
-
Yamamoto N, Sato T, Kawasaki K, Murosaki S, Yamamoto Y. A nonradioisotope, enzymatic assay for 2-deoxyglucose uptake in L6 skeletal muscle cells cultured in a 96-well microplate. Anal Biochem 2006; 351: 139-145.
-
(2006)
Anal Biochem
, vol.351
, pp. 139-145
-
-
Yamamoto, N.1
Sato, T.2
Kawasaki, K.3
Murosaki, S.4
Yamamoto, Y.5
-
23
-
-
0036068126
-
Synaptic adaptation to repeated hypoglycemia depends on the utilization of monocarboxylates in Guinea pig hippocampal slices
-
Sakurai T, Yang B, Takata T, Yokono K. Synaptic adaptation to repeated hypoglycemia depends on the utilization of monocarboxylates in Guinea pig hippocampal slices. Diabetes 2002; 51: 430-438.
-
(2002)
Diabetes
, vol.51
, pp. 430-438
-
-
Sakurai, T.1
Yang, B.2
Takata, T.3
Yokono, K.4
-
24
-
-
77957810913
-
Amyloid-β neurotoxicity restricts glucose window for neuronal survival in rat hippocampal slice cultures
-
Wang X, Song X, Takata T, Miichi Y, Yokono K, Sakurai T. Amyloid-β neurotoxicity restricts glucose window for neuronal survival in rat hippocampal slice cultures. Exp Geront 2010; 45: 904-908.
-
(2010)
Exp Geront
, vol.45
, pp. 904-908
-
-
Wang, X.1
Song, X.2
Takata, T.3
Miichi, Y.4
Yokono, K.5
Sakurai, T.6
-
25
-
-
1842734654
-
Glucose transporter expression in the central nervous system: relationship to synaptic function
-
McEwena BS, Reagan LP. Glucose transporter expression in the central nervous system: relationship to synaptic function. Eur J Pharmacol 2004; 490: 13- 24.
-
(2004)
Eur J Pharmacol
, vol.490
, pp. 13-24
-
-
McEwena, B.S.1
Reagan, L.P.2
-
26
-
-
0035213226
-
Human C-peptide dose dependently prevents early neuropathy in the BB/Wor-rat
-
Zhang W, Yorek M, Pierson CR, Murakawa Y, Breidenbach A, Sima AAF. Human C-peptide dose dependently prevents early neuropathy in the BB/Wor-rat. Int J Exp Diabetes Res 2001; 2: 187-193.
-
(2001)
Int J Exp Diabetes Res
, vol.2
, pp. 187-193
-
-
Zhang, W.1
Yorek, M.2
Pierson, C.R.3
Murakawa, Y.4
Breidenbach, A.5
Sima, A.A.F.6
-
27
-
-
33846910806
-
Is lactate food for neurons? Comparison of monocarboxylater substrate in brain and muscle
-
Bergersen LH. Is lactate food for neurons? Comparison of monocarboxylater substrate in brain and muscle. Neuroscience 2007; 145: 11-19.
-
(2007)
Neuroscience
, vol.145
, pp. 11-19
-
-
Bergersen, L.H.1
-
28
-
-
35448984525
-
Different effects of monocarboxylates on neuronal survival and β-amyloid toxicity
-
Wang XN, Takata T, Sakurai T, Yokono K. Different effects of monocarboxylates on neuronal survival and β-amyloid toxicity. Eur J Neurosci 2007; 26: 2142-2150.
-
(2007)
Eur J Neurosci
, vol.26
, pp. 2142-2150
-
-
Wang, X.N.1
Takata, T.2
Sakurai, T.3
Yokono, K.4
-
29
-
-
78650719636
-
Amyloid-β Triggers the Release of Neuronal Hexokinase 1 from Mitochondria
-
Saraiva LM, da Silva GS, Galina A etal. Amyloid-β Triggers the Release of Neuronal Hexokinase 1 from Mitochondria. PLoS ONE 2010; 5: e15230.
-
(2010)
PLoS ONE
, vol.5
-
-
Saraiva, L.M.1
da Silva, G.S.2
Galina, A.3
-
30
-
-
67649803186
-
Amyloid beta, mitochondrial structural and functional dynamics in Alzheimer's disease
-
Reddy PH. Amyloid beta, mitochondrial structural and functional dynamics in Alzheimer's disease. Exp Neurol 2009; 218: 286-292.
-
(2009)
Exp Neurol
, vol.218
, pp. 286-292
-
-
Reddy, P.H.1
-
31
-
-
77749308402
-
Amyloid oligomers: formation and toxicity of Abeta oligomers
-
Sakono M, Zako T. Amyloid oligomers: formation and toxicity of Abeta oligomers. FEBS J 2010; 277: 1348-1358.
-
(2010)
FEBS J
, vol.277
, pp. 1348-1358
-
-
Sakono, M.1
Zako, T.2
-
32
-
-
36348935683
-
Soluble Abeta inhibits specific signal transduction cascades common to the insulin receptor pathway
-
Townsend M, Mehta T, Selkoe DJ. Soluble Abeta inhibits specific signal transduction cascades common to the insulin receptor pathway. J Biol Chem 2007; 282: 33305-33312.
-
(2007)
J Biol Chem
, vol.282
, pp. 33305-33312
-
-
Townsend, M.1
Mehta, T.2
Selkoe, D.J.3
-
33
-
-
44049089139
-
Amyloid-beta binds to the extracellular cysteine-rich domain of Frizzled and inhibits Wnt / beta-catenin signaling
-
Magdesian MH, Carvalho MM, Mendes FA etal. Amyloid-beta binds to the extracellular cysteine-rich domain of Frizzled and inhibits Wnt / beta-catenin signaling. J Biol Chem 2008; 283: 9359-9368.
-
(2008)
J Biol Chem
, vol.283
, pp. 9359-9368
-
-
Magdesian, M.H.1
Carvalho, M.M.2
Mendes, F.A.3
-
34
-
-
38549141544
-
Amyloid beta oligomers (A beta(1-42) globulomer) suppress spontaneous synaptic activity by inhibition of P / Q-type calcium currents
-
Nimmrich V, Grimm C, Draguhn A etal. Amyloid beta oligomers (A beta(1-42) globulomer) suppress spontaneous synaptic activity by inhibition of P / Q-type calcium currents. J Neurosci 2008; 28: 788-797.
-
(2008)
J Neurosci
, vol.28
, pp. 788-797
-
-
Nimmrich, V.1
Grimm, C.2
Draguhn, A.3
-
35
-
-
50649114611
-
Amyloid-beta dynamics correlate with neurological status in the injured human brain
-
Brody D, Magnoni S, Schwetye K etal. Amyloid-beta dynamics correlate with neurological status in the injured human brain. Science 2008; 321: 1221-1224.
-
(2008)
Science
, vol.321
, pp. 1221-1224
-
-
Brody, D.1
Magnoni, S.2
Schwetye, K.3
-
36
-
-
73949089674
-
Amyloid seeds formed by cellular uptake, concentration, and aggregation of the amyloid-beta peptide
-
Hu X, Crick SL, Bu G, Frieden C, Pappu RV, Lee JM. Amyloid seeds formed by cellular uptake, concentration, and aggregation of the amyloid-beta peptide. Proc Natl Acad Sci U S A 2009; 106: 20324-20329.
-
(2009)
Proc Natl Acad Sci U S A
, vol.106
, pp. 20324-20329
-
-
Hu, X.1
Crick, S.L.2
Bu, G.3
Frieden, C.4
Pappu, R.V.5
Lee, J.M.6
-
37
-
-
60549084867
-
Protection of synapses against Alzheimer's-linked toxins: insulin signaling prevents the pathogenic binding of Aβ oligomers
-
De Felice FG, Vieira MNN, Bomfim TR etal. Protection of synapses against Alzheimer's-linked toxins: insulin signaling prevents the pathogenic binding of Aβ oligomers. Proc Natl Acad Sci U S A 2009; 106: 1971-1976.
-
(2009)
Proc Natl Acad Sci U S A
, vol.106
, pp. 1971-1976
-
-
De Felice, F.G.1
Vieira, M.N.N.2
Bomfim, T.R.3
-
38
-
-
1842734649
-
Modulation of memory by insulin and glucose: neuropsychological observations in Alzheimer's disease
-
Watson GS, Craft S. Modulation of memory by insulin and glucose: neuropsychological observations in Alzheimer's disease. Eur J Pharmacol 2004; 490: 97-113.
-
(2004)
Eur J Pharmacol
, vol.490
, pp. 97-113
-
-
Watson, G.S.1
Craft, S.2
|