Inverse agonism at α2A adrenoceptors augments the hypophagic effect of sibutramine in rats

Obesity

Volumn 19, Issue 10, 2011, Pages 1979-1986

  Janhunen, Sanna K ^a,b   Van Der Zwaal, Esther M ^a   La Fleur, Susanne E ^a,c   Adan, Roger A H ^a  

^a UNIVERSITY MEDICAL CENTER UTRECHT   (Netherlands)

^b ORION CORPORATION   (Finland)

^c UNIVERSITY OF AMSTERDAM   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

2 (1 METHYL 2 ISOINDOLINYLMETHYL) 2 IMIDAZOLINE; 2 (2 METHOXY 1,4 BENZODIOXAN 2 YL) 2 IMIDAZOLINE; 2 [[2 (2,6 DIMETHOXYPHENOXY)ETHYL]AMINOMETHYL] 1,4 BENZODIOXAN; 2,3,6,7 TETRAHYDRO 1' METHYL 5 [[2' METHYL 4' (5 METHYL 1,2,4 OXADIAZOL 3 YL) 4 BIPHENYLYL]CARBONYL]SPIRO[FURO[2,3 F]INDOLE 3,4' PIPERIDINE]; ALPHA 1A ADRENERGIC RECEPTOR; ALPHA 2A ADRENERGIC RECEPTOR; ATIPAMEZOLE; IMILOXAN; METERGOLINE; SEROTONIN 1 RECEPTOR; SEROTONIN 1B RECEPTOR; SEROTONIN 2 RECEPTOR; SEROTONIN 2C RECEPTOR; SEROTONIN 7 RECEPTOR; SIBUTRAMINE;

ADRENERGIC RECEPTOR BLOCKING; ANIMAL EXPERIMENT; ARTICLE; CALORIC INTAKE; CALORIC RESTRICTION; CONTROLLED STUDY; DRUG ACTIVITY; ENERGY EXPENDITURE; FLUID INTAKE; HYPOPHAGIC EFFECT; LOCOMOTION; MALE; MEAL FREQUENCY; MEAL SIZE; NONHUMAN; NUTRITIONAL PARAMETERS; RAT; SATIETY; WEIGHT REDUCTION;

ADRENERGIC ALPHA-AGONISTS; ADRENERGIC ALPHA-ANTAGONISTS; ANIMALS; APPETITE DEPRESSANTS; CYCLOBUTANES; ENERGY INTAKE; FEEDING BEHAVIOR; HYPERPHAGIA; LOCOMOTION; MALE; METERGOLINE; NOREPINEPHRINE; OBESITY; PRAZOSIN; RATS; RATS, WISTAR; RECEPTORS, ADRENERGIC, ALPHA-2; RECEPTORS, SEROTONIN; SATIETY RESPONSE; SEROTONIN RECEPTOR AGONISTS;

RATTUS;

EID: 80053224125     PISSN: 19307381     EISSN: 1930739X     Source Type: Journal    
DOI: 10.1038/oby.2011.51     Document Type: Article

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