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Volumn 397, Issue 1, 2000, Pages 93-102

Enantioselective behavioral effects of sibutramine metabolites

Author keywords

Antidepressant; Desmethylsibutramine; Didemethylsibutramine; Food intake; Locomotor activity; Obesity; Sibutramine

Indexed keywords

DRUG METABOLITE; SIBUTRAMINE;

EID: 0034717220     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0014-2999(00)00216-8     Document Type: Article
Times cited : (53)

References (15)
  • 1
    • 0023814888 scopus 로고
    • The pharmacology of sibutramine hydrochloride (BTS 54 524), a new antidepressant which induces rapid nor-adrenergic down-regulation
    • Buckett W.R., Thomas P.C., Luscombe G.P. The pharmacology of sibutramine hydrochloride (BTS 54 524), a new antidepressant which induces rapid nor-adrenergic down-regulation. Prog. Neuro-Psychopharmacol. Biol. Psychiat. 12:1988;575-584.
    • (1988) Prog. Neuro-Psychopharmacol. Biol. Psychiat. , vol.12 , pp. 575-584
    • Buckett, W.R.1    Thomas, P.C.2    Luscombe, G.P.3
  • 3
    • 0026510184 scopus 로고
    • A comparison of the effects of sibutramine hydrochloride, bupropion and methamphetamine on dopaminergic function: Evidence that dopamine is not a pharmacological target for sibutramine
    • Heal D.J., Frankland A.T.J., Gosden J., Hutchins L.J., Prow M.R., Luscombe G.P., Buckett W.R. A comparison of the effects of sibutramine hydrochloride, bupropion and methamphetamine on dopaminergic function: evidence that dopamine is not a pharmacological target for sibutramine. Psychopharmacology. 107:1992;303-309.
    • (1992) Psychopharmacology , vol.107 , pp. 303-309
    • Heal, D.J.1    Frankland, A.T.J.2    Gosden, J.3    Hutchins, L.J.4    Prow, M.R.5    Luscombe, G.P.6    Buckett, W.R.7
  • 4
    • 0031820091 scopus 로고    scopus 로고
    • Sibtramine: A novel anti-obesity drug. A review of the pharmacological evidence to differentiate it from D-amphetamine and D-fenfluramine
    • Heal D.J., Aspley S., Prow M.R., Jackson H.C., Martin K.F., Cheetham S.C. Sibtramine: a novel anti-obesity drug. A review of the pharmacological evidence to differentiate it from D-amphetamine and D-fenfluramine. Int. J. Obes. 22(Suppl. 1):1998;S18-S28.
    • (1998) Int. J. Obes. , vol.22 , Issue.SUPPL. 1 , pp. 18-S28
    • Heal, D.J.1    Aspley, S.2    Prow, M.R.3    Jackson, H.C.4    Martin, K.F.5    Cheetham, S.C.6
  • 5
    • 0030759773 scopus 로고    scopus 로고
    • Investigation of the mechanisms underyling the hypophagic effects of the 5-HT and noradrenaline reuptake inhibitor, sibutramine, in the rat
    • Jackson H.C., Bearham M.C., Hutchins L.J., Mazurkiewicz S.E., Needham A.M., Heal D.J. Investigation of the mechanisms underyling the hypophagic effects of the 5-HT and noradrenaline reuptake inhibitor, sibutramine, in the rat. Br. J. Pharmacol. 121:1997;1613-1618.
    • (1997) Br. J. Pharmacol. , vol.121 , pp. 1613-1618
    • Jackson, H.C.1    Bearham, M.C.2    Hutchins, L.J.3    Mazurkiewicz, S.E.4    Needham, A.M.5    Heal, D.J.6
  • 6
    • 0030860731 scopus 로고    scopus 로고
    • Comparison of the effects of sibutramine and other monoamine reuptake inhibtors on food intake in the rat
    • Jackson H.C., Needham A.M., Hutchins L.J., Mazurkiewicz S.E., Heal D.J. Comparison of the effects of sibutramine and other monoamine reuptake inhibtors on food intake in the rat. Br. J. Pharmacol. 121:1997;1758-1762.
    • (1997) Br. J. Pharmacol. , vol.121 , pp. 1758-1762
    • Jackson, H.C.1    Needham, A.M.2    Hutchins, L.J.3    Mazurkiewicz, S.E.4    Heal, D.J.5
  • 8
    • 0014138387 scopus 로고
    • New rat feeding jar: Use in study of relationships of food intake and body weight
    • Joy R.T., Emma C.P., Mayer J. New rat feeding jar: use in study of relationships of food intake and body weight. J. Appl. Physiol. 23:1967;589-590.
    • (1967) J. Appl. Physiol. , vol.23 , pp. 589-590
    • Joy, R.T.1    Emma, C.P.2    Mayer, J.3
  • 9
    • 0024503310 scopus 로고
    • The contribution of metabolites to the rapid and potent down regulation of rats cortical β-adrenoreceptors by the putative antidepressant sibutramine hydrochloride
    • Luscombe G.P., Hopcroft R.H., Thomas P.C., Buckett W.R. The contribution of metabolites to the rapid and potent down regulation of rats cortical β-adrenoreceptors by the putative antidepressant sibutramine hydrochloride. Neuropharmacology. 28:1989;129-134.
    • (1989) Neuropharmacology , vol.28 , pp. 129-134
    • Luscombe, G.P.1    Hopcroft, R.H.2    Thomas, P.C.3    Buckett, W.R.4
  • 10
    • 0025022589 scopus 로고
    • Effect on radiolabelled-monoamine uptake in vitro of plasma taken from healthy volunteers administered the antidepressant sibutramine HCl
    • Luscombe G.P., Slater N.A., Lyons M.B., Wynne R.D., Scheinbaum M.L., Buckett W.R. Effect on radiolabelled-monoamine uptake in vitro of plasma taken from healthy volunteers administered the antidepressant sibutramine HCl. Psychopharmacology. 100:1990;345-349.
    • (1990) Psychopharmacology , vol.100 , pp. 345-349
    • Luscombe, G.P.1    Slater, N.A.2    Lyons, M.B.3    Wynne, R.D.4    Scheinbaum, M.L.5    Buckett, W.R.6
  • 11
    • 0343583132 scopus 로고
    • Comparison of the effects of sibutramine and D-amphetamine on extracellular dopamine levels in rat nucleus accumbens: An in vivo microdialysis study
    • 346 pp.
    • Martin K.F., Hannon S.D., Czudek C., Heal D.J., Buckett W.R. Comparison of the effects of sibutramine and D-amphetamine on extracellular dopamine levels in rat nucleus accumbens: an in vivo microdialysis study. Br. J. Pharmacol. 114:1995;. 346 pp.
    • (1995) Br. J. Pharmacol. , vol.114
    • Martin, K.F.1    Hannon, S.D.2    Czudek, C.3    Heal, D.J.4    Buckett, W.R.5
  • 12
    • 0028793881 scopus 로고
    • Pharmacological profile of hypericum extract: Effect on serotonin uptake by postsynaptic receptors
    • Perovic S., Müller W.E.G. Pharmacological profile of hypericum extract: effect on serotonin uptake by postsynaptic receptors. Arzneim. Forsh, Drug Res. 45:1995;1145-1148.
    • (1995) Arzneim. Forsh, Drug Res. , vol.45 , pp. 1145-1148
    • Perovic, S.1    Müller, W.E.G.2
  • 13
    • 0017618768 scopus 로고
    • Depression: A new animal model sensitive to antidepressant treatment
    • Porsolt R.D., Le Pichon M., Jalfre M. Depression: a new animal model sensitive to antidepressant treatment. Nature. 266:1977;730-732.
    • (1977) Nature , vol.266 , pp. 730-732
    • Porsolt, R.D.1    Le Pichon, M.2    Jalfre, M.3
  • 14
    • 0030942814 scopus 로고    scopus 로고
    • Sibutramine: A review of the pharmacology of a novel anti-obesity agent
    • Stock M.J. Sibutramine: a review of the pharmacology of a novel anti-obesity agent. Int. J. Obes. 21(Suppl. 1):1997;S25-S29.
    • (1997) Int. J. Obes. , vol.21 , Issue.SUPPL. 1 , pp. 25-S29
    • Stock, M.J.1
  • 15
    • 0023426876 scopus 로고
    • A psychomotor stimulant theory of addiction
    • Wise R.A., Bozarth M.A. A psychomotor stimulant theory of addiction. Psychol. Rev. 94:1987;469-492.
    • (1987) Psychol. Rev. , vol.94 , pp. 469-492
    • Wise, R.A.1    Bozarth, M.A.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.