-
1
-
-
0037066466
-
-
S. Mandala, R. Hajdu, J. Bergstrom, E. Quackenbush, J. Xie, J. Milligan, R. Thornton, G.-J. Shei, D. Card, C. Keohane, M. Rosenbach, J. Hale, C.L. Lynch, K. Rupprecht, W. Parsons, and H. Rosen Science 296 2002 346 349
-
(2002)
Science
, vol.296
, pp. 346-349
-
-
Mandala, S.1
Hajdu, R.2
Bergstrom, J.3
Quackenbush, E.4
Xie, J.5
Milligan, J.6
Thornton, R.7
Shei, G.-J.8
Card, D.9
Keohane, C.10
Rosenbach, M.11
Hale, J.12
Lynch, C.L.13
Rupprecht, K.14
Parsons, W.15
Rosen, H.16
-
2
-
-
0034696075
-
-
T. Fujita, N. Matsumoto, S. Uchida, T. Kohno, T. Shimizu, R. Hirose, K. Yanada, W. Kurio, and K. Watabe Bioorg. Med. Chem. Lett. 10 2000 337 339
-
(2000)
Bioorg. Med. Chem. Lett.
, vol.10
, pp. 337-339
-
-
Fujita, T.1
Matsumoto, N.2
Uchida, S.3
Kohno, T.4
Shimizu, T.5
Hirose, R.6
Yanada, K.7
Kurio, W.8
Watabe, K.9
-
6
-
-
63149102747
-
-
G. Evindar, A.L. Satz, S.G. Bernier, M.J. Kavarana, E. Doyle, J. Lorusso, N. Taghizadeh, K. Halley, A. Hutchings, M.S. Kelley, A.D. Wright, A.K. Saha, G. Hannig, B.A. Morgan, and W.F. Westlin Bioorg. Med. Chem. Lett. 19 2009 2315 2319
-
(2009)
Bioorg. Med. Chem. Lett.
, vol.19
, pp. 2315-2319
-
-
Evindar, G.1
Satz, A.L.2
Bernier, S.G.3
Kavarana, M.J.4
Doyle, E.5
Lorusso, J.6
Taghizadeh, N.7
Halley, K.8
Hutchings, A.9
Kelley, M.S.10
Wright, A.D.11
Saha, A.K.12
Hannig, G.13
Morgan, B.A.14
Westlin, W.F.15
-
7
-
-
23444460121
-
-
R. Albert, K. Hinterding, V. Brinkmann, D. Guerini, C. Müller-Hartwieg, H. Knecht, C. Simeon, M. Streiff, T. Wagner, K. Welzenbach, F. Zécri, M. Zollinger, N. Cooke, and E. Francotte J. Med. Chem. 48 2005 5373 5377
-
(2005)
J. Med. Chem.
, vol.48
, pp. 5373-5377
-
-
Albert, R.1
Hinterding, K.2
Brinkmann, V.3
Guerini, D.4
Müller-Hartwieg, C.5
Knecht, H.6
Simeon, C.7
Streiff, M.8
Wagner, T.9
Welzenbach, K.10
Zécri, F.11
Zollinger, M.12
Cooke, N.13
Francotte, E.14
-
11
-
-
76149093586
-
-
L. Kappos, E.W. Radue, P. O'Connor, C. Polman, R. Hohlfeld, P. Calabresi, K. Selmaj, C. Agoropoulou, M. Leyk, L. Zhang-Auberson, and P. Burtin N. Engl. J. Med. 362 2010 387 401
-
(2010)
N. Engl. J. Med.
, vol.362
, pp. 387-401
-
-
Kappos, L.1
Radue, E.W.2
O'Connor, P.3
Polman, C.4
Hohlfeld, R.5
Calabresi, P.6
Selmaj, K.7
Agoropoulou, C.8
Leyk, M.9
Zhang-Auberson, L.10
Burtin, P.11
-
12
-
-
76149140914
-
-
J.A. Cohen, F. Barkhof, G. Comi, H.P. Hartung, B.O. Khatri, X. Montalban, J. Pelletier, R. Capra, P. Gallo, G. Izquierdo, K. Tiel-Wilck, A. De Vera, J. Jin, T. Stites, S. Wu, S. Aradhye, and L. Kappos N. Engl. J. Med. 362 2010 402 415
-
(2010)
N. Engl. J. Med.
, vol.362
, pp. 402-415
-
-
Cohen, J.A.1
Barkhof, F.2
Comi, G.3
Hartung, H.P.4
Khatri, B.O.5
Montalban, X.6
Pelletier, J.7
Capra, R.8
Gallo, P.9
Izquierdo, G.10
Tiel-Wilck, K.11
De Vera, A.12
Jin, J.13
Stites, T.14
Wu, S.15
Aradhye, S.16
Kappos, L.17
-
13
-
-
79551674537
-
-
J.W. Choi, S.E. Gardell, D.R. Herr, R. Rivera, C.W. Lee, K. Noguchi, S.T. Teo, Y.C. Yung, M. Lu, G. Kennedy, and J. Chun Proc. Natl. Acad. Sci. 108 2011 751 756
-
(2011)
Proc. Natl. Acad. Sci.
, vol.108
, pp. 751-756
-
-
Choi, J.W.1
Gardell, S.E.2
Herr, D.R.3
Rivera, R.4
Lee, C.W.5
Noguchi, K.6
Teo, S.T.7
Yung, Y.C.8
Lu, M.9
Kennedy, G.10
Chun, J.11
-
14
-
-
78049480679
-
-
V. Brinkmann, A. Billich, T. Baumruker, P. Heining, R. Schmouder, G. Francis, S. Arahye, and P. Burtin Nat. Rev. Drug Disc. 9 2010 883 897
-
(2010)
Nat. Rev. Drug Disc.
, vol.9
, pp. 883-897
-
-
Brinkmann, V.1
Billich, A.2
Baumruker, T.3
Heining, P.4
Schmouder, R.5
Francis, G.6
Arahye, S.7
Burtin, P.8
-
16
-
-
78449267550
-
-
D. Pchejetski, T. Bohler, L. Brizuela, L. Sauer, N. Doumerc, M. Golzio, V. Salunkhe, J. Teissie, B. Malavaud, J. Waxman, and O. Cuvillier Am. Assoc. Cancer Res. 9 2010 8651 8661
-
(2010)
Am. Assoc. Cancer Res.
, vol.9
, pp. 8651-8661
-
-
Pchejetski, D.1
Bohler, T.2
Brizuela, L.3
Sauer, L.4
Doumerc, N.5
Golzio, M.6
Salunkhe, V.7
Teissie, J.8
Malavaud, B.9
Waxman, J.10
Cuvillier, O.11
-
17
-
-
77954535502
-
-
F. Tonelli, K.G. Lim, C. Loveridge, J. Long, S.M. Pitson, G. Tigyi, R. Bittman, S. Pyne, and N.J. Pyne Cell. Signalling 22 2010 1536 1542
-
(2010)
Cell. Signalling
, vol.22
, pp. 1536-1542
-
-
Tonelli, F.1
Lim, K.G.2
Loveridge, C.3
Long, J.4
Pitson, S.M.5
Tigyi, G.6
Bittman, R.7
Pyne, S.8
Pyne, N.J.9
-
18
-
-
77954514553
-
-
W.J. Valentine, G.N. Kiss, J. Liu, S. E, M. Gotoh, K. Murakami-Murofushi, T.C. Pham, D.L. Baker, A.L. Parrill, X. Lu, C. Sun, R. Bittman, N.J. Pyne, and G. Tigyi Cell. Signalling 22 2010 1543 1553
-
(2010)
Cell. Signalling
, vol.22
, pp. 1543-1553
-
-
Valentine, W.J.1
Kiss, G.N.2
Liu, J.3
Gotoh, S.E.M.4
Murakami-Murofushi, K.5
Pham, T.C.6
Baker, D.L.7
Parrill, A.L.8
Lu, X.9
Sun, C.10
Bittman, R.11
Pyne, N.J.12
Tigyi, G.13
-
19
-
-
69049084440
-
-
M. Bektas, S.P. Johnson, W.E. Poe, D.D. Bigner, and H.S. Friedman Cancer Chemother. Pharmaol. 64 2009 1053 1058
-
(2009)
Cancer Chemother. Pharmaol.
, vol.64
, pp. 1053-1058
-
-
Bektas, M.1
Johnson, S.P.2
Poe, W.E.3
Bigner, D.D.4
Friedman, H.S.5
-
20
-
-
33644893873
-
-
For prior syntheses of FTY720 employing TRIS see Ref. 7 and
-
For prior syntheses of FTY720 employing TRIS see Ref. 7 and: S. Kim, H. Lee, M. Lee, and T. Lee Synthesis 2006 753 755
-
(2006)
Synthesis
, pp. 753-755
-
-
Kim, S.1
Lee, H.2
Lee, M.3
Lee, T.4
-
21
-
-
0028943870
-
-
For other syntheses of FTY720 see
-
For other syntheses of FTY720 see: K. Adachi, T. Kohara, N. Nakao, M. Arita, K. Chiba, T. Mishina, S. Sasaki, and T. Fujita Bioorg. Med. Chem. Lett. 5 1995 853 865
-
(1995)
Bioorg. Med. Chem. Lett.
, vol.5
, pp. 853-865
-
-
Adachi, K.1
Kohara, T.2
Nakao, N.3
Arita, M.4
Chiba, K.5
Mishina, T.6
Sasaki, S.7
Fujita, T.8
-
22
-
-
17144435270
-
-
M. Kiuchi, K. Adachi, T. Kohara, M. Minoguchi, T. Hanano, Y. Aoki, T. Mishina, M. Arita, N. Nakao, M. Ohtsuki, Y. Hoshino, K. Teshima, K. Chiba, S. Sasaki, and T. Fujita J. Med. Chem. 43 2000 2946 2961
-
(2000)
J. Med. Chem.
, vol.43
, pp. 2946-2961
-
-
Kiuchi, M.1
Adachi, K.2
Kohara, T.3
Minoguchi, M.4
Hanano, T.5
Aoki, Y.6
Mishina, T.7
Arita, M.8
Nakao, N.9
Ohtsuki, M.10
Hoshino, Y.11
Teshima, K.12
Chiba, K.13
Sasaki, S.14
Fujita, T.15
-
25
-
-
0042238070
-
-
K. Hinterding, S. Cottens, R. Albert, F. Zecri, P. Buehlmayer, C. Spanka, V. Brinkmann, P. Nussbaumer, P. Ettmayer, K. Hoegenauer, N. Gray, and S. Pan Synthesis 2003 1667 1670
-
(2003)
Synthesis
, pp. 1667-1670
-
-
Hinterding, K.1
Cottens, S.2
Albert, R.3
Zecri, F.4
Buehlmayer, P.5
Spanka, C.6
Brinkmann, V.7
Nussbaumer, P.8
Ettmayer, P.9
Hoegenauer, K.10
Gray, N.11
Pan, S.12
-
26
-
-
4444334770
-
-
J.J. Hale, L. Yan, W.E. Neway, R. Hajdu, J.D. Bergstrom, J.A. Milligan, G.-J. Shei, G.L. Chrebet, R.A. Thornton, D. Card, M. Rosenbach, H. Rosen, and S. Mandala Bioorg. Med. Chem. 12 2004 4803 4807
-
(2004)
Bioorg. Med. Chem.
, vol.12
, pp. 4803-4807
-
-
Hale, J.J.1
Yan, L.2
Neway, W.E.3
Hajdu, R.4
Bergstrom, J.D.5
Milligan, J.A.6
Shei, G.-J.7
Chrebet, G.L.8
Thornton, R.A.9
Card, D.10
Rosenbach, M.11
Rosen, H.12
Mandala, S.13
-
31
-
-
79952574651
-
-
For syntheses of analogues of FTY720 see, (Note: the formation and analysis of the obtained cis/trans isomers is not reported by these authors)
-
For syntheses of analogues of FTY720 see R.Y.Y. Ko, J.C.K. Chu, and P. Chiu Tetrahedron 67 2011 2542 2547 (Note: the formation and analysis of the obtained cis/trans isomers is not reported by these authors)
-
(2011)
Tetrahedron
, vol.67
, pp. 2542-2547
-
-
Ko, R.Y.Y.1
Chu, J.C.K.2
Chiu, P.3
-
33
-
-
20844443104
-
-
M. Kiuchi, K. Adachi, A. Tomatsu, M. Chino, S. Takeda, Y. Tanaka, Y. Maeda, N. Sato, N. Mitsutomi, K. Sugahara, and K. Chiba Bioorg. Med. Chem. 13 2005 425 432
-
(2005)
Bioorg. Med. Chem.
, vol.13
, pp. 425-432
-
-
Kiuchi, M.1
Adachi, K.2
Tomatsu, A.3
Chino, M.4
Takeda, S.5
Tanaka, Y.6
Maeda, Y.7
Sato, N.8
Mitsutomi, N.9
Sugahara, K.10
Chiba, K.11
-
34
-
-
2442534745
-
-
J.J. Hale, W. Neway, S.G. Mills, R. Hajdu, C.A. Keohane, M. Rosenbach, J. Milligan, G.-J. Shei, G. Chrebet, J. Bergstrom, D. Card, G.C. Koo, S.L. Koprak, J.J. Jackson, H. Rosen, and S. Mandala Bioorg. Med. Chem. Lett. 14 2004 3351 3355
-
(2004)
Bioorg. Med. Chem. Lett.
, vol.14
, pp. 3351-3355
-
-
Hale, J.J.1
Neway, W.2
Mills, S.G.3
Hajdu, R.4
Keohane, C.A.5
Rosenbach, M.6
Milligan, J.7
Shei, G.-J.8
Chrebet, G.9
Bergstrom, J.10
Card, D.11
Koo, G.C.12
Koprak, S.L.13
Jackson, J.J.14
Rosen, H.15
Mandala, S.16
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