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Volumn 69, Issue 11, 2004, Pages 3950-3952

Iron-catalyzed cross-coupling reactions. A scalable synthesis of the immunosuppressive agent FTY720

Author keywords

[No Author keywords available]

Indexed keywords

BENZENE; DERIVATIVES; IRON; MAGNESIUM COMPOUNDS; SYNTHESIS (CHEMICAL);

EID: 2442680336     PISSN: 00223263     EISSN: None     Source Type: Journal    
DOI: 10.1021/jo049885d     Document Type: Article
Times cited : (143)

References (81)
  • 1
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    • Diederich, F., Stang, P. J., Eds.; Wiley-VCH: Weinheim
    • (a) Metal-catalyzed Cross-coupling Reactions; Diederich, F., Stang, P. J., Eds.; Wiley-VCH: Weinheim, 1998.
    • (1998) Metal-catalyzed Cross-coupling Reactions
  • 2
    • 0003535745 scopus 로고    scopus 로고
    • Miyaura, N., Ed.; Top. Curr. Chem.; Springer: Berlin
    • (b) Cross-Coupling Reactions: A Practical Guide; Miyaura, N., Ed.; Top. Curr. Chem.; Springer: Berlin, 2002; Vol. 219.
    • (2002) Cross-Coupling Reactions: A Practical Guide , vol.219
  • 3
    • 0000891348 scopus 로고
    • Trost, B. M., Fleming, I., Eds.; Pergamon: Oxford
    • (c) Knight, D. W. In Comprehensive Organic Synthesis; Trost, B. M., Fleming, I., Eds.; Pergamon: Oxford, 1991; Vol. 3; pp 481-520.
    • (1991) Comprehensive Organic Synthesis , vol.3 , pp. 481-520
    • Knight, D.W.1
  • 54
    • 1642361256 scopus 로고    scopus 로고
    • See, however, the highly efficient iron-catalyzed cross-coupling of arylmagnesium halides with alkyl halides disclosed recently: (a) Nakamura, M.; Matsuo, K.; Ito, S.; Nakamura, E. J. Am. Chem. Soc. 2004, 126, 3686-3687.
    • (2004) J. Am. Chem. Soc. , vol.126 , pp. 3686-3687
    • Nakamura, M.1    Matsuo, K.2    Ito, S.3    Nakamura, E.4
  • 65
    • 85039531395 scopus 로고    scopus 로고
    • See: http://www.transplantationschweiz.ch/d/fty720/.
  • 70
    • 85039517055 scopus 로고    scopus 로고
    • EP 0627406 (Yoshitomi Pharmaceutical), 1994-12-07
    • (a) EP 0627406 (Yoshitomi Pharmaceutical), 1994-12-07.
  • 71
    • 85039542172 scopus 로고    scopus 로고
    • JP11310556 (Yoshitomi Pharmaceutical), 1999-11-09
    • (b) JP11310556 (Yoshitomi Pharmaceutical), 1999-11-09.
  • 72
    • 85039537353 scopus 로고    scopus 로고
    • PCT/CN00/00046 (Hangzhou Zhongmei Huadong Pharmaceutical Co. Ltd.), 2000-11-03
    • (c) PCT/CN00/00046 (Hangzhou Zhongmei Huadong Pharmaceutical Co. Ltd.), 2000-11-03.
  • 73
    • 17744417463 scopus 로고    scopus 로고
    • For studies on other immunomodulators from this laboratory, see: (a) Fürstner, A. Angew. Chem., Int. Ed. 2003, 42, 3582.
    • (2003) Angew. Chem., Int. Ed. , vol.42 , pp. 3582
    • Fürstner, A.1
  • 80
    • 85039539018 scopus 로고    scopus 로고
    • note
    • Alcohol 6b (ca. 20%) accompanying product 6a originates from the work up and is not detected in the crude mixture, cf. Experimental Section.
  • 81
    • 85039513490 scopus 로고    scopus 로고
    • note
    • Similar difficulties are mentioned in ref 17b.


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.