Monoamine oxidase inhibition by selected anilide derivatives

European Journal of Medicinal Chemistry

Volumn 46, Issue 10, 2011, Pages 5162-5174

  Legoabe, Lesetja ^a   Kruger, Johann ^a   Petzer, Anél ^a   Bergh, Jacobus J ^a   Petzer, Jacobus P ^a  

^a NORTH WEST UNIVERSITY   (South Africa)

Author keywords

Anilide; Benzimidazole; Molecular docking; Monoamine oxidase B; Reversible inhibitor; Selectivity

Indexed keywords

ANILIDE; MONOAMINE OXIDASE A INHIBITOR; MONOAMINE OXIDASE B INHIBITOR; N (3 BROMOPHENYL) 3 (3 CYANOPHENYL)PROP 2 ENAMIDE; N (3 BROMOPHENYL) 3 (3 HYDROXYPHENYL)PROP 2 ENAMIDE; N (3 BROMOPHENYL) 3 (4 CYANOPHENYL)PROP 2 ENAMIDE; N (3 BROMOPHENYL) 3 (4 HYDROXYPHENYL)PROP 2 ENAMIDE; N (3 BROMOPHENYL) 3 PHENYLPROP 2 ENAMIDE; N (3 BROMOPHENYL) 4 PHENYLBUT 3 ENAMIDE; N (3 BROMOPHENYL) 5 PHENYLPENTA 2,4 DIENAMIDE; N (3 CHLOROPHENYL) 3 (3 CYANOPHENYL)PROP 2 ENAMIDE; N (3 CHLOROPHENYL) 3 (3 HYDROXYPHENYL)PROP 2 ENAMIDE; N (3 CHLOROPHENYL) 3 (4 CYANOPHENYL)PROP 2 ENAMIDE; N (3 CHLOROPHENYL) 3 (4 HYDROXYPHENYL)PROP 2 ENAMIDE; N (3 CHLOROPHENYL) 3 PHENYLPROP 2 ENAMIDE; N (3 CHLOROPHENYL) 4 PHENYLBUT 3 ENAMIDE; N (3 CHLOROPHENYL) 5 PHENYLPENTA 2,4 DIENAMIDE; N (3 METHYLPHENYL) 4 PHENYLBUT 3 ENAMIDE; N (3 METHYLPHENYL) 5 PHENYLPENTA 2,4 DIENAMIDE; UNCLASSIFIED DRUG;

ARTICLE; BINDING AFFINITY; COMPETITIVE INHIBITION; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG BINDING SITE; DRUG DESIGN; DRUG POTENCY; DRUG SELECTIVITY; DRUG SYNTHESIS; ENZYME INHIBITION; IC 50; MOLECULAR DOCKING; SUBSTITUTION REACTION;

ANILIDES; CATALYTIC DOMAIN; HUMANS; INHIBITORY CONCENTRATION 50; MODELS, MOLECULAR; MONOAMINE OXIDASE; MONOAMINE OXIDASE INHIBITORS; PROTEIN BINDING; RECOMBINANT PROTEINS;

EID: 80053182563     PISSN: 02235234     EISSN: 17683254     Source Type: Journal    
DOI: 10.1016/j.ejmech.2011.08.036     Document Type: Article

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