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Volumn 68, Issue 3, 2011, Pages 603-610

Modulatory effects of curcumin on multi-drug resistance-associated protein 5 in pancreatic cancer cells

Author keywords

5 Fluorouracil; Curcumin; Multi drug resistance associated protein 5; Pancreatic cancer

Indexed keywords

CURCUMIN; FLUOROURACIL; MONOCLONAL ANTIBODY; MULTIDRUG RESISTANCE PROTEIN 5; MULTIDRUG RESISTANCE PROTEIN 5 ANTIBODY; UNCLASSIFIED DRUG;

EID: 80053117135     PISSN: 03445704     EISSN: 14320843     Source Type: Journal    
DOI: 10.1007/s00280-010-1515-6     Document Type: Article
Times cited : (46)

References (42)
  • 1
    • 48349107006 scopus 로고    scopus 로고
    • Gemcitabine based combination chemotherapy in advanced pancreatic cancer-indirect comparison
    • 1471-2407-8-192[pii]10.1186/1471-2407-8-192 18611273 10.1186/1471-2407-8- 192
    • A Sultana P Ghaneh D Cunningham N Starling JP Neoptolemos CT Smith 2008 Gemcitabine based combination chemotherapy in advanced pancreatic cancer-indirect comparison BMC Cancer 8 192 1471-2407-8-192[pii]10.1186/1471- 2407-8-192 18611273 10.1186/1471-2407-8-192
    • (2008) BMC Cancer , vol.8 , pp. 192
    • Sultana, A.1    Ghaneh, P.2    Cunningham, D.3    Starling, N.4    Neoptolemos, J.P.5    Smith, C.T.6
  • 3
    • 0036074018 scopus 로고    scopus 로고
    • Mammalian abc transporters in health and disease
    • 10.1146/annurev.biochem.71.102301.093055102301.093055[pii] 12045106 10.1146/annurev.biochem.71.102301.093055 1:CAS:528:DC%2BD38Xos1Clt74%3D
    • P Borst RO Elferink 2002 Mammalian abc transporters in health and disease Annu Rev Biochem 71 537 592 10.1146/annurev.biochem.71.102301.093055102301. 093055[pii] 12045106 10.1146/annurev.biochem.71.102301.093055 1:CAS:528:DC%2BD38Xos1Clt74%3D
    • (2002) Annu Rev Biochem , vol.71 , pp. 537-592
    • Borst, P.1    Elferink, R.O.2
  • 4
    • 18644378003 scopus 로고    scopus 로고
    • Expression and localization of human multidrug resistance protein (abcc) family members in pancreatic carcinoma
    • 10.1002/ijc.20831 15688370 10.1002/ijc.20831
    • J Konig M Hartel AT Nies ME Martignoni J Guo MW Buchler H Friess D Keppler 2005 Expression and localization of human multidrug resistance protein (abcc) family members in pancreatic carcinoma Int J Cancer 115 3 359 367 10.1002/ijc.20831 15688370 10.1002/ijc.20831
    • (2005) Int J Cancer , vol.115 , Issue.3 , pp. 359-367
    • Konig, J.1    Hartel, M.2    Nies, A.T.3    Martignoni, M.E.4    Guo, J.5    Buchler, M.W.6    Friess, H.7    Keppler, D.8
  • 5
    • 33644775686 scopus 로고    scopus 로고
    • Targeting multidrug resistance in cancer
    • nrd1984[pii]10.1038/nrd1984 16518375 10.1038/nrd1984 1:CAS:528: DC%2BD28XhvFOlsr8%3D
    • G Szakacs JK Paterson JA Ludwig C Booth-Genthe MM Gottesman 2006 Targeting multidrug resistance in cancer Nat Rev Drug Discov 5 3 219 234 nrd1984[pii]10.1038/nrd1984 16518375 10.1038/nrd1984 1:CAS:528: DC%2BD28XhvFOlsr8%3D
    • (2006) Nat Rev Drug Discov , vol.5 , Issue.3 , pp. 219-234
    • Szakacs, G.1    Paterson, J.K.2    Ludwig, J.A.3    Booth-Genthe, C.4    Gottesman, M.M.5
  • 6
    • 57449109392 scopus 로고    scopus 로고
    • Atp-binding cassette c transporters in human pancreatic carcinoma cell lines. Upregulation in 5-fluorouracil-resistant cells
    • 000178884[pii]10.1159/000178884 19077464 10.1159/000178884 1:CAS:528:DC%2BD1MXktFWjtb0%3D
    • W Hagmann R Jesnowski R Faissner C Guo JM Lohr 2009 Atp-binding cassette c transporters in human pancreatic carcinoma cell lines. Upregulation in 5-fluorouracil-resistant cells Pancreatology 9 1-2 136 144 000178884[pii]10. 1159/000178884 19077464 10.1159/000178884 1:CAS:528:DC%2BD1MXktFWjtb0%3D
    • (2009) Pancreatology , vol.9 , Issue.12 , pp. 136-144
    • Hagmann, W.1    Jesnowski, R.2    Faissner, R.3    Guo, C.4    Lohr, J.M.5
  • 7
    • 77956868652 scopus 로고    scopus 로고
    • Interdependence of gemcitabine treatment, transporter expression and resistance in human pancreatic carcinoma cells
    • 10.1593/neo.10576 1:CAS:528:DC%2BC3cXhtFGmtrfL
    • W Hagmann R Jesnowski J Matthias Löhr 2010 Interdependence of gemcitabine treatment, transporter expression and resistance in human pancreatic carcinoma cells Neoplasma 12 9 740 747 10.1593/neo.10576 1:CAS:528: DC%2BC3cXhtFGmtrfL
    • (2010) Neoplasma , vol.12 , Issue.9 , pp. 740-747
    • Hagmann, W.1    Jesnowski, R.2    Matthias Löhr, J.3
  • 8
    • 33748306343 scopus 로고    scopus 로고
    • The determinants of sensitivity and acquired resistance to gemcitabine differ in non-small cell lung cancer: A role of abcc5 in gemcitabine sensitivity
    • 5/7/1800[pii]10.1158/1535-7163.MCT-06-0025 16891466 10.1158/1535-7163. MCT-06-0025 1:CAS:528:DC%2BD28XnslWksb0%3D
    • T Oguri H Achiwa S Sato Y Bessho Y Takano M Miyazaki H Muramatsu H Maeda T Niimi R Ueda 2006 The determinants of sensitivity and acquired resistance to gemcitabine differ in non-small cell lung cancer: a role of abcc5 in gemcitabine sensitivity Mol Cancer Ther 5 7 1800 1806 5/7/1800[pii]10.1158/1535-7163.MCT- 06-0025 16891466 10.1158/1535-7163.MCT-06-0025 1:CAS:528:DC%2BD28XnslWksb0%3D
    • (2006) Mol Cancer Ther , vol.5 , Issue.7 , pp. 1800-1806
    • Oguri, T.1    Achiwa, H.2    Sato, S.3    Bessho, Y.4    Takano, Y.5    Miyazaki, M.6    Muramatsu, H.7    Maeda, H.8    Niimi, T.9    Ueda, R.10
  • 9
    • 39749084704 scopus 로고    scopus 로고
    • Development of inhibitors of atp-binding cassette drug transporters: Present status and challenges
    • 10.1517/17425255.4.2.205 18248313 10.1517/17425255.4.2.205 1:CAS:528:DC%2BD1cXhsVSgurY%3D
    • S Shukla CP Wu SV Ambudkar 2008 Development of inhibitors of atp-binding cassette drug transporters: present status and challenges Expert Opin Drug Metab Toxicol 4 2 205 223 10.1517/17425255.4.2.205 18248313 10.1517/17425255.4.2.205 1:CAS:528:DC%2BD1cXhsVSgurY%3D
    • (2008) Expert Opin Drug Metab Toxicol , vol.4 , Issue.2 , pp. 205-223
    • Shukla, S.1    Wu, C.P.2    Ambudkar, S.V.3
  • 10
    • 33748356494 scopus 로고    scopus 로고
    • Modulation of the function of the multidrug resistance-linked atp-binding cassette transporter abcg2 by the cancer chemopreventive agent curcumin
    • 5/8/1995[pii]10.1158/1535-7163.MCT-06-0087 16928820 10.1158/1535-7163. MCT-06-0087 1:CAS:528:DC%2BD28XosVansL8%3D
    • W Chearwae S Shukla P Limtrakul SV Ambudkar 2006 Modulation of the function of the multidrug resistance-linked atp-binding cassette transporter abcg2 by the cancer chemopreventive agent curcumin Mol Cancer Ther 5 8 1995 2006 5/8/1995[pii]10.1158/1535-7163.MCT-06-0087 16928820 10.1158/1535-7163.MCT-06- 0087 1:CAS:528:DC%2BD28XosVansL8%3D
    • (2006) Mol Cancer Ther , vol.5 , Issue.8 , pp. 1995-2006
    • Chearwae, W.1    Shukla, S.2    Limtrakul, P.3    Ambudkar, S.V.4
  • 11
    • 2142711101 scopus 로고    scopus 로고
    • Flavonoids are inhibitors of breast cancer resistance protein (abcg2)-mediated transport
    • 15102949 10.1124/mol.65.5.1208 1:CAS:528:DC%2BD2cXjsFKgtro%3D
    • SZ Zhang XN Yang ME Morris 2004 Flavonoids are inhibitors of breast cancer resistance protein (abcg2)-mediated transport Mol Pharmacol 65 5 1208 1216 15102949 10.1124/mol.65.5.1208 1:CAS:528:DC%2BD2cXjsFKgtro%3D
    • (2004) Mol Pharmacol , vol.65 , Issue.5 , pp. 1208-1216
    • Zhang, S.Z.1    Yang, X.N.2    Morris, M.E.3
  • 12
    • 25444524567 scopus 로고    scopus 로고
    • Modulatory effects of plant phenols on human multidrug-resistance proteins 1, 4 and 5 (abcc1, 4 and 5)
    • EJB4888[pii]10.1111/j.1742-4658.2005.04888.x 16156793 10.1111/j.1742-4658.2005.04888.x 1:CAS:528:DC%2BD2MXhtVKru77F
    • CP Wu AM Calcagno SB Hladky SV Ambudkar MA Barrand 2005 Modulatory effects of plant phenols on human multidrug-resistance proteins 1, 4 and 5 (abcc1, 4 and 5) FEBS J 272 18 4725 4740 EJB4888[pii]10.1111/j.1742-4658.2005. 04888.x 16156793 10.1111/j.1742-4658.2005.04888.x 1:CAS:528:DC%2BD2MXhtVKru77F
    • (2005) FEBS J , vol.272 , Issue.18 , pp. 4725-4740
    • Wu, C.P.1    Calcagno, A.M.2    Hladky, S.B.3    Ambudkar, S.V.4    Barrand, M.A.5
  • 13
    • 34447506459 scopus 로고    scopus 로고
    • Modulation of function of three abc drug transporters, p-glycoprotein (abcb1), mitoxantrone resistance protein (abcg2) and multidrug resistance protein 1 (abcc1) by tetrahydrocurcumin, a major metabolite of curcumin
    • 10.1007/s11010-006-9302-8 16960658 10.1007/s11010-006-9302-8 1:CAS:528:DC%2BD2sXjvFKis7o%3D
    • P Limtrakul W Chearwae S Shukla C Phisalphong SV Ambudkar 2007 Modulation of function of three abc drug transporters, p-glycoprotein (abcb1), mitoxantrone resistance protein (abcg2) and multidrug resistance protein 1 (abcc1) by tetrahydrocurcumin, a major metabolite of curcumin Mol Cell Biochem 296 1-2 85 95 10.1007/s11010-006-9302-8 16960658 10.1007/s11010-006-9302-8 1:CAS:528:DC%2BD2sXjvFKis7o%3D
    • (2007) Mol Cell Biochem , vol.296 , Issue.12 , pp. 85-95
    • Limtrakul, P.1    Chearwae, W.2    Shukla, S.3    Phisalphong, C.4    Ambudkar, S.V.5
  • 14
    • 0037103569 scopus 로고    scopus 로고
    • Modulation of p-glycoprotein expression and function by curcumin in multidrug-resistant human kb cells
    • S0006295202012248[pii] 12167476 10.1016/S0006-2952(02)01224-8 1:CAS:528:DC%2BD38XmtVWls7g%3D
    • S Anuchapreeda P Leechanachai MM Smith SV Ambudkar PN Limtrakul 2002 Modulation of p-glycoprotein expression and function by curcumin in multidrug-resistant human kb cells Biochem Pharmacol 64 4 573 582 S0006295202012248[pii] 12167476 10.1016/S0006-2952(02)01224-8 1:CAS:528:DC%2BD38XmtVWls7g%3D
    • (2002) Biochem Pharmacol , vol.64 , Issue.4 , pp. 573-582
    • Anuchapreeda, S.1    Leechanachai, P.2    Smith, M.M.3    Ambudkar, S.V.4    Limtrakul, P.N.5
  • 15
    • 34248573808 scopus 로고    scopus 로고
    • Curcumin potentiates antitumor activity of gemcitabine in an orthotopic model of pancreatic cancer through suppression of proliferation, angiogenesis, and inhibition of nuclear factor-kappab-regulated gene products
    • 67/8/3853[pii]10.1158/0008-5472.CAN-06-4257 17440100 10.1158/0008-5472. CAN-06-4257 1:CAS:528:DC%2BD2sXkt1Kitb0%3D
    • AB Kunnumakkara S Guha S Krishnan P Diagaradjane J Gelovani BB Aggarwal 2007 Curcumin potentiates antitumor activity of gemcitabine in an orthotopic model of pancreatic cancer through suppression of proliferation, angiogenesis, and inhibition of nuclear factor-kappab-regulated gene products Cancer Res 67 8 3853 3861 67/8/3853[pii]10.1158/0008-5472.CAN-06-4257 17440100 10.1158/0008-5472.CAN-06-4257 1:CAS:528:DC%2BD2sXkt1Kitb0%3D
    • (2007) Cancer Res , vol.67 , Issue.8 , pp. 3853-3861
    • Kunnumakkara, A.B.1    Guha, S.2    Krishnan, S.3    Diagaradjane, P.4    Gelovani, J.5    Aggarwal, B.B.6
  • 16
    • 36849018017 scopus 로고    scopus 로고
    • Curcumin enhances the effects of 5-fluorouracil and oxaliplatin in mediating growth inhibition of colon cancer cells by modulating egfr and igf-1r
    • 10.1002/ijc.23097 17918158 10.1002/ijc.23097 1:CAS:528:DC%2BD2sXhsVOnsrrK
    • BB Patel R Sengupta S Qazi H Vachhani Y Yu AK Rishi AP Majumdar 2008 Curcumin enhances the effects of 5-fluorouracil and oxaliplatin in mediating growth inhibition of colon cancer cells by modulating egfr and igf-1r Int J Cancer 122 2 267 273 10.1002/ijc.23097 17918158 10.1002/ijc.23097 1:CAS:528:DC%2BD2sXhsVOnsrrK
    • (2008) Int J Cancer , vol.122 , Issue.2 , pp. 267-273
    • Patel, B.B.1    Sengupta, R.2    Qazi, S.3    Vachhani, H.4    Yu, Y.5    Rishi, A.K.6    Majumdar, A.P.7
  • 17
    • 77955485060 scopus 로고    scopus 로고
    • Systemic administration of polymeric nanoparticle-encapsulated curcumin (nanocurc) blocks tumor growth and metastases in preclinical models of pancreatic cancer
    • doi: 1535-7163.MCT-10-0172
    • Bisht S, Mizuma M, Feldmann G, Ottenhof NA, Hong SM, Pramanik D, Chenna V, Karikari C, Sharma R, Goggins MG, Rudek MA, Ravi R, Maitra A (2010) Systemic administration of polymeric nanoparticle-encapsulated curcumin (nanocurc) blocks tumor growth and metastases in preclinical models of pancreatic cancer. Mol Cancer Ther 9(8):2255-2264. doi: 1535-7163.MCT-10-0172
    • (2010) Mol Cancer Ther , vol.9 , Issue.8 , pp. 2255-2264
    • Bisht, S.1    Mizuma, M.2    Feldmann, G.3    Ottenhof, N.A.4    Hong, S.M.5    Pramanik, D.6    Chenna, V.7    Karikari, C.8    Sharma, R.9    Goggins, M.G.10    Ma, R.11    Ravi, R.12    Maitra, A.13
  • 18
    • 51649118928 scopus 로고    scopus 로고
    • Phase ii trial of curcumin in patients with advanced pancreatic cancer
    • 14/14/4491[pii]10.1158/1078-0432.CCR-08-0024 18628464 10.1158/1078-0432.CCR-08-0024 1:CAS:528:DC%2BD1cXosFGitLw%3D
    • N Dhillon BB Aggarwal RA Newman RA Wolff AB Kunnumakkara JL Abbruzzese CS Ng V Badmaev R Kurzrock 2008 Phase ii trial of curcumin in patients with advanced pancreatic cancer Clin Cancer Res 14 14 4491 4499 14/14/4491[pii]10. 1158/1078-0432.CCR-08-0024 18628464 10.1158/1078-0432.CCR-08-0024 1:CAS:528:DC%2BD1cXosFGitLw%3D
    • (2008) Clin Cancer Res , vol.14 , Issue.14 , pp. 4491-4499
    • Dhillon, N.1    Aggarwal, B.B.2    Newman, R.A.3    Wolff, R.A.4    Kunnumakkara, A.B.5    Abbruzzese, J.L.6    Ng, C.S.7    Badmaev, V.8    Kurzrock, R.9
  • 19
    • 20044383925 scopus 로고    scopus 로고
    • The multidrug resistance protein 5 (abcc5) confers resistance to 5-fluorouracil and transports its monophosphorylated metabolites
    • 4/5/855[pii]10.1158/1535-7163.MCT-04-0291 15897250 10.1158/1535-7163.MCT- 04-0291 1:CAS:528:DC%2BD2MXktFyktL4%3D
    • S Pratt RL Shepard RA Kandasamy PA Johnston W Perry 3rd AH Dantzig 2005 The multidrug resistance protein 5 (abcc5) confers resistance to 5-fluorouracil and transports its monophosphorylated metabolites Mol Cancer Ther 4 5 855 863 4/5/855[pii]10.1158/1535-7163.MCT-04-0291 15897250 10.1158/1535-7163.MCT-04-0291 1:CAS:528:DC%2BD2MXktFyktL4%3D
    • (2005) Mol Cancer Ther , vol.4 , Issue.5 , pp. 855-863
    • Pratt, S.1    Shepard, R.L.2    Kandasamy, R.A.3    Johnston, P.A.4    Perry III, W.5    Dantzig, A.H.6
  • 20
    • 0030997276 scopus 로고    scopus 로고
    • In vivo and in vitro evidence for nonrestricted transport of 2′, 7′-bis(2-carboxyethyl)-5(6)-carboxyfluorescein tetraacetoxymethyl ester at the blood-brain barrier
    • 9023295 1:CAS:528:DyaK2sXivVWku7o%3D
    • T Hirohashi T Terasaki M Shigetoshi Y Sugiyama 1997 In vivo and in vitro evidence for nonrestricted transport of 2′, 7′-bis(2-carboxyethyl)- 5(6)-carboxyfluorescein tetraacetoxymethyl ester at the blood-brain barrier J Pharmacol Exp Ther 280 2 813 819 9023295 1:CAS:528:DyaK2sXivVWku7o%3D
    • (1997) J Pharmacol Exp Ther , vol.280 , Issue.2 , pp. 813-819
    • Hirohashi, T.1    Terasaki, T.2    Shigetoshi, M.3    Sugiyama, Y.4
  • 21
    • 0033551671 scopus 로고    scopus 로고
    • Pabc11 (also known as moat-c and mrp5), a member of the abc family of proteins, has anion transporter activity but does not confer multidrug resistance when overexpressed in human embryonic kidney 293 cells
    • 10.1074/jbc.274.33.23541 1:CAS:528:DyaK1MXltlKmsrw%3D
    • MA McAleer MA Breen NL White N Matthews 1999 Pabc11 (also known as moat-c and mrp5), a member of the abc family of proteins, has anion transporter activity but does not confer multidrug resistance when overexpressed in human embryonic kidney 293 cells J Bio Chem 274 33 23541 23548 10.1074/jbc.274.33. 23541 1:CAS:528:DyaK1MXltlKmsrw%3D
    • (1999) J Bio Chem , vol.274 , Issue.33 , pp. 23541-23548
    • McAleer, M.A.1    Breen, M.A.2    White, N.L.3    Matthews, N.4
  • 22
    • 72949086481 scopus 로고    scopus 로고
    • Pharmacokinetically guided dose adjustment of 5-fluorouracil: A rational approach to improving therapeutic outcomes
    • 10.1093/jnci/djp328 19841331 10.1093/jnci/djp328 1:CAS:528: DC%2BD1MXhsVKls7vN
    • MW Saif A Choma SJ Salamone E Chu 2009 Pharmacokinetically guided dose adjustment of 5-fluorouracil: a rational approach to improving therapeutic outcomes J Natl Cancer Inst 101 22 1543 1552 10.1093/jnci/djp328 19841331 10.1093/jnci/djp328 1:CAS:528:DC%2BD1MXhsVKls7vN
    • (2009) J Natl Cancer Inst , vol.101 , Issue.22 , pp. 1543-1552
    • Saif, M.W.1    Choma, A.2    Salamone, S.J.3    Chu, E.4
  • 23
    • 84982289409 scopus 로고    scopus 로고
    • Benefit of adjuvant chemotherapy for resectable gastric cancer: A meta-analysis
    • GASTRIC (Global Advanced/Adjuvant Stomach Tumor Research International Collaboration) Group PX. 10.1001/jama.2010.534 20442389 10.1001/jama.2010.534
    • GASTRIC (Global Advanced/Adjuvant Stomach Tumor Research International Collaboration) Group PX K Oba T Burzykowski S Michiels Y Ohashi JP Pignon P Rougier J Sakamoto D Sargent M Sasako E Van Cutsem M Buyse 2010 Benefit of adjuvant chemotherapy for resectable gastric cancer: a meta-analysis JAMA 303 17 1729 1737 10.1001/jama.2010.534 20442389 10.1001/jama.2010.534
    • (2010) JAMA , vol.303 , Issue.17 , pp. 1729-1737
    • Oba, K.1    Burzykowski, T.2    Michiels, S.3    Ohashi, Y.4    Pignon, J.P.5    Rougier, P.6    Sakamoto, J.7    Sargent, D.8    Sasako, M.9    Van Cutsem, E.10    Buyse, M.11
  • 27
    • 0038752694 scopus 로고    scopus 로고
    • Characterization of the transport of nucleoside analog drugs by the human multidrug resistance proteins mrp4 and mrp5
    • 12695538 10.1124/mol.63.5.1094 1:CAS:528:DC%2BD3sXjt12lu7Y%3D
    • G Reid P Wielinga N Zelcer M De Haas L Van Deemter J Wijnholds J Balzarini P Borst 2003 Characterization of the transport of nucleoside analog drugs by the human multidrug resistance proteins mrp4 and mrp5 Mol Pharmacol 63 5 1094 1103 12695538 10.1124/mol.63.5.1094 1:CAS:528:DC%2BD3sXjt12lu7Y%3D
    • (2003) Mol Pharmacol , vol.63 , Issue.5 , pp. 1094-1103
    • Reid, G.1    Wielinga, P.2    Zelcer, N.3    De Haas, M.4    Van Deemter, L.5    Wijnholds, J.6    Balzarini, J.7    Borst, P.8
  • 28
    • 70349751649 scopus 로고    scopus 로고
    • Mitochondrial expression and functional activity of breast cancer resistance protein in different multiple drug-resistant cell lines
    • 0008-5472.CAN-08-4315[pii]10.1158/0008-5472.CAN-08-4315 19706772 10.1158/0008-5472.CAN-08-4315 1:CAS:528:DC%2BD1MXhtFaku73I
    • M Solazzo O Fantappie M D'Amico C Sassoli A Tani G Cipriani C Bogani L Formigli R Mazzanti 2009 Mitochondrial expression and functional activity of breast cancer resistance protein in different multiple drug-resistant cell lines Cancer Res 69 18 7235 7242 0008-5472.CAN-08-4315[pii]10.1158/0008-5472.CAN-08- 4315 19706772 10.1158/0008-5472.CAN-08-4315 1:CAS:528:DC%2BD1MXhtFaku73I
    • (2009) Cancer Res , vol.69 , Issue.18 , pp. 7235-7242
    • Solazzo, M.1    Fantappie, O.2    D'Amico, M.3    Sassoli, C.4    Tani, A.5    Cipriani, G.6    Bogani, C.7    Formigli, L.8    Mazzanti, R.9
  • 29
    • 0032534459 scopus 로고    scopus 로고
    • Apoptosis-independent alterations in membrane dynamics induced by curcumin
    • S0014-4827(98)94225-2[pii]10.1006/excr.1998.4225 9851871 10.1006/excr.1998.4225 1:CAS:528:DyaK1cXotVWqsLg%3D
    • E Jaruga A Sokal S Chrul G Bartosz 1998 Apoptosis-independent alterations in membrane dynamics induced by curcumin Exp Cell Res 245 2 303 312 S0014-4827(98)94225-2[pii]10.1006/excr.1998.4225 9851871 10.1006/excr.1998.4225 1:CAS:528:DyaK1cXotVWqsLg%3D
    • (1998) Exp Cell Res , vol.245 , Issue.2 , pp. 303-312
    • Jaruga, E.1    Sokal, A.2    Chrul, S.3    Bartosz, G.4
  • 30
    • 0042531890 scopus 로고    scopus 로고
    • Mrp8, atp-binding cassette c11 (abcc11), is a cyclic nucleotide efflux pump and a resistance factor for fluoropyrimidines 2′, 3′-dideoxycytidine and 9′-(2′-phosphonylmethoxyethyl)adenine
    • 10.1074/jbc.M304059200M304059200[pii] 10.1074/jbc.M304059200 1:CAS:528:DC%2BD3sXlvFOgu74%3D
    • Y Guo E Kotova ZS Chen K Lee E Hopper-Borge MG Belinsky GD Kruh 2003 Mrp8, atp-binding cassette c11 (abcc11), is a cyclic nucleotide efflux pump and a resistance factor for fluoropyrimidines 2′, 3′-dideoxycytidine and 9′-(2′-phosphonylmethoxyethyl)adenine J Bio Chem 278 32 29509 29514 10.1074/jbc.M304059200M304059200[pii] 10.1074/jbc.M304059200 1:CAS:528:DC%2BD3sXlvFOgu74%3D
    • (2003) J Bio Chem , vol.278 , Issue.32 , pp. 29509-29514
    • Guo, Y.1    Kotova, E.2    Chen, Z.S.3    Lee, K.4    Hopper-Borge, E.5    Belinsky, M.G.6    Kruh, G.D.7
  • 31
    • 70350400865 scopus 로고    scopus 로고
    • Identification of gas1 as an epirubicin resistance-related gene in human gastric cancer cells with a partially randomized small interfering rna library
    • M109.028068[pii]10.1074/jbc.M109.028068 19638344 10.1074/jbc.M109.028068 1:CAS:528:DC%2BD1MXhtFCgs7%2FP
    • L Zhao Y Pan Y Gang H Wang H Jin J Tie L Xia Y Zhang L He L Yao T Qiao T Li Z Liu D Fan 2009 Identification of gas1 as an epirubicin resistance-related gene in human gastric cancer cells with a partially randomized small interfering rna library J Biol Chem 284 39 26273 26285 M109.028068[pii]10.1074/jbc.M109. 028068 19638344 10.1074/jbc.M109.028068 1:CAS:528:DC%2BD1MXhtFCgs7%2FP
    • (2009) J Biol Chem , vol.284 , Issue.39 , pp. 26273-26285
    • Zhao, L.1    Pan, Y.2    Gang, Y.3    Wang, H.4    Jin, H.5    Tie, J.6    Xia, L.7    Zhang, Y.8    He, L.9    Yao, L.10    Qiao, T.11    Li, T.12    Liu, Z.13    Fan, D.14
  • 32
    • 0037305821 scopus 로고    scopus 로고
    • Curcumin (diferuloylmethane) down-regulates the constitutive activation of nuclear factor-kappa b and ikappabalpha kinase in human multiple myeloma cells, leading to suppression of proliferation and induction of apoptosis
    • 10.1182/blood-2002-05-13202002-05-1320[pii] 12393461 10.1182/blood-2002- 05-1320 1:CAS:528:DC%2BD3sXptVCisg%3D%3D
    • AC Bharti N Donato S Singh BB Aggarwal 2003 Curcumin (diferuloylmethane) down-regulates the constitutive activation of nuclear factor-kappa b and ikappabalpha kinase in human multiple myeloma cells, leading to suppression of proliferation and induction of apoptosis Blood 101 3 1053 1062 10.1182/blood-2002-05-13202002-05-1320[pii] 12393461 10.1182/blood-2002-05-1320 1:CAS:528:DC%2BD3sXptVCisg%3D%3D
    • (2003) Blood , vol.101 , Issue.3 , pp. 1053-1062
    • Bharti, A.C.1    Donato, N.2    Singh, S.3    Aggarwal, B.B.4
  • 33
    • 0032943591 scopus 로고    scopus 로고
    • The nuclear factor-kappa b rela transcription factor is constitutively activated in human pancreatic adenocarcinoma cells
    • 9918209 1:CAS:528:DyaK1MXhtVShtLY%3D
    • W Wang JL Abbruzzese DB Evans L Larry KR Cleary PJ Chiao 1999 The nuclear factor-kappa b rela transcription factor is constitutively activated in human pancreatic adenocarcinoma cells Clin Cancer Res 5 1 119 127 9918209 1:CAS:528:DyaK1MXhtVShtLY%3D
    • (1999) Clin Cancer Res , vol.5 , Issue.1 , pp. 119-127
    • Wang, W.1    Abbruzzese, J.L.2    Evans, D.B.3    Larry, L.4    Cleary, K.R.5    Chiao, P.J.6
  • 34
    • 0037150228 scopus 로고    scopus 로고
    • Induction of human mdr1 gene expression by 2-acetylaminofluorene is mediated by effectors of the phosphoinositide 3-kinase pathway that activate nf-kappab signaling
    • 11960367 10.1038/sj.onc.1205117 1:CAS:528:DC%2BD38XivVeltbs%3D
    • MT Kuo Z Liu Y Wei YC Lin-Lee S Tatebe GB Mills H Unate 2002 Induction of human mdr1 gene expression by 2-acetylaminofluorene is mediated by effectors of the phosphoinositide 3-kinase pathway that activate nf-kappab signaling Oncogene 21 13 1945 1954 11960367 10.1038/sj.onc.1205117 1:CAS:528: DC%2BD38XivVeltbs%3D
    • (2002) Oncogene , vol.21 , Issue.13 , pp. 1945-1954
    • Kuo, M.T.1    Liu, Z.2    Wei, Y.3    Lin-Lee, Y.C.4    Tatebe, S.5    Mills, G.B.6    Unate, H.7
  • 35
    • 34249878632 scopus 로고    scopus 로고
    • Sonic hedgehog promotes multiple drug resistance by regulation of drug transport
    • 1210356[pii]10.1038/sj.onc.1210356 17353904 10.1038/sj.onc.1210356 1:CAS:528:DC%2BD2sXptFemtbc%3D
    • J Sims-Mourtada JG Izzo J Ajani KS Chao 2007 Sonic hedgehog promotes multiple drug resistance by regulation of drug transport Oncogene 26 38 5674 5679 1210356[pii]10.1038/sj.onc.1210356 17353904 10.1038/sj.onc.1210356 1:CAS:528:DC%2BD2sXptFemtbc%3D
    • (2007) Oncogene , vol.26 , Issue.38 , pp. 5674-5679
    • Sims-Mourtada, J.1    Izzo, J.G.2    Ajani, J.3    Chao, K.S.4
  • 36
    • 61649094969 scopus 로고    scopus 로고
    • Curcumin as a possible lead compound against hormone-independent, multidrug-resistant breast cancer
    • NYAS03699[pii]10.1111/j.1749-6632.2009.03699.x 19250217 10.1111/j.1749-6632.2009.03699.x 1:CAS:528:DC%2BD1MXktFKlt7g%3D
    • M Labbozzetta M Notarbartolo P Poma A Maurici L Inguglia P Marchetti M Rizzi R Baruchello D Simoni N D'Alessandro 2009 Curcumin as a possible lead compound against hormone-independent, multidrug-resistant breast cancer Ann N Y Acad Sci 1155 278 283 NYAS03699[pii]10.1111/j.1749-6632.2009.03699.x 19250217 10.1111/j.1749-6632.2009.03699.x 1:CAS:528:DC%2BD1MXktFKlt7g%3D
    • (2009) Ann N y Acad Sci , vol.1155 , pp. 278-283
    • Labbozzetta, M.1    Notarbartolo, M.2    Poma, P.3    Maurici, A.4    Inguglia, L.5    Marchetti, P.6    Rizzi, M.7    Baruchello, R.8    Simoni, D.9    D'Alessandro, N.10
  • 37
    • 37549051274 scopus 로고    scopus 로고
    • Bioavailability of curcumin: Problems and promises
    • 10.1021/mp700113r 17999464 10.1021/mp700113r 1:CAS:528:DC%2BD2sXht12gsrnF
    • P Anand AB Kunnumakkara RA Newman BB Aggarwal 2007 Bioavailability of curcumin: Problems and promises Mol Pharm 4 6 807 818 10.1021/mp700113r 17999464 10.1021/mp700113r 1:CAS:528:DC%2BD2sXht12gsrnF
    • (2007) Mol Pharm , vol.4 , Issue.6 , pp. 807-818
    • Anand, P.1    Kunnumakkara, A.B.2    Newman, R.A.3    Aggarwal, B.B.4
  • 38
    • 34248205135 scopus 로고    scopus 로고
    • Polymeric nanoparticle-encapsulated curcumin ("Nanocurcumin"): A novel strategy for human cancer therapy
    • 1477-3155-5-3[pii]10.1186/1477-3155-5-3 17439648 10.1186/1477-3155-5-3
    • S Bisht G Feldmann S Soni R Ravi C Karikar A Maitra 2007 Polymeric nanoparticle-encapsulated curcumin ("Nanocurcumin"): a novel strategy for human cancer therapy J Nanobiotechnology 5 3 1477-3155-5-3[pii]10.1186/1477- 3155-5-3 17439648 10.1186/1477-3155-5-3
    • (2007) J Nanobiotechnology , vol.5 , pp. 3
    • Bisht, S.1    Feldmann, G.2    Soni, S.3    Ravi, R.4    Karikar, C.5    Maitra, A.6
  • 39
    • 57849106304 scopus 로고    scopus 로고
    • An in vitro study of liposomal curcumin: Stability, toxicity and biological activity in human lymphocytes and epstein-barr virus-transformed human b-cells
    • S0378-5173(08)00620-0[pii]10.1016/j.ijpharm.2008.09.009 18840516 10.1016/j.ijpharm.2008.09.009 1:CAS:528:DC%2BD1cXhsFCjurvM
    • C Chen TD Johnston H Jeon R Gedaly PP McHugh TG Burke D Ranjan 2009 An in vitro study of liposomal curcumin: Stability, toxicity and biological activity in human lymphocytes and epstein-barr virus-transformed human b-cells Int J Pharm 366 1-2 133 139 S0378-5173(08)00620-0[pii]10.1016/j.ijpharm.2008.09.009 18840516 10.1016/j.ijpharm.2008.09.009 1:CAS:528:DC%2BD1cXhsFCjurvM
    • (2009) Int J Pharm , vol.366 , Issue.12 , pp. 133-139
    • Chen, C.1    Johnston, T.D.2    Jeon, H.3    Gedaly, R.4    McHugh, P.P.5    Burke, T.G.6    Ranjan, D.7
  • 40
    • 62749095208 scopus 로고    scopus 로고
    • Enhancement of oral absorption of curcumin by self-microemulsifying drug delivery systems
    • S0378-5173(08)00824-7[pii]10.1016/j.ijpharm.2008.12.009 19124065 10.1016/j.ijpharm.2008.12.009 1:CAS:528:DC%2BD1MXjslWktbg%3D
    • J Cui B Yu Y Zhao W Zhu H Li H Lou G Zhai 2009 Enhancement of oral absorption of curcumin by self-microemulsifying drug delivery systems Int J Pharm 371 1-2 148 155 S0378-5173(08)00824-7[pii]10.1016/j.ijpharm.2008.12.009 19124065 10.1016/j.ijpharm.2008.12.009 1:CAS:528:DC%2BD1MXjslWktbg%3D
    • (2009) Int J Pharm , vol.371 , Issue.12 , pp. 148-155
    • Cui, J.1    Yu, B.2    Zhao, Y.3    Zhu, W.4    Li, H.5    Lou, H.6    Zhai, G.7
  • 42
    • 79953054576 scopus 로고    scopus 로고
    • The epr effect: Unique features of tumor blood vessels for drug delivery, factors involved, and limitations and augmentation of the effect
    • doi:S0169-409X(10)00090-6 [pii]. 10.1016/j.addr.2010.04.009
    • Fang J, Nakamura H, Maeda H (2010) The epr effect: unique features of tumor blood vessels for drug delivery, factors involved, and limitations and augmentation of the effect. Adv Drug Deliv Rev. doi:S0169-409X(10)00090-6 [pii] 10.1016/j.addr.2010.04.009
    • (2010) Adv Drug Deliv Rev
    • Fang, J.1    Nakamura, H.2    Maeda, H.3


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