-
1
-
-
0025166212
-
Efflux of bis-carboxyethyl-carboxyfluorescein (BCECF) by a novel ATP-dependent transport mechanism in epithelial cells
-
ALLEN, C. N., HARPUR, E. S., GRAY, T. J., SIMMONS, N. L. AND HIRST, B. H.: Efflux of bis-carboxyethyl-carboxyfluorescein (BCECF) by a novel ATP-dependent transport mechanism in epithelial cells. Biochem. Biophys. Res. Commun. 172: 262-267, 1990.
-
(1990)
Biochem. Biophys. Res. Commun.
, vol.172
, pp. 262-267
-
-
Allen, C.N.1
Harpur, E.S.2
Gray, T.J.3
Simmons, N.L.4
Hirst, B.H.5
-
2
-
-
0022349214
-
Peptides and the blood-brain barrier. Lipophilicity as a predictor of permeability
-
BANKS, W. A. AND KASTIN, A. J.: Peptides and the blood-brain barrier. Lipophilicity as a predictor of permeability. Brain Res. Bull. 15: 287-292, 1985.
-
(1985)
Brain Res. Bull.
, vol.15
, pp. 287-292
-
-
Banks, W.A.1
Kastin, A.J.2
-
4
-
-
0022350218
-
Restrictive transport of a lipid-soluble peptide (cyclosporin) through the blood-brain barrier
-
CEFALU, W. T. AND PARDRIDGE, W. M.: Restrictive transport of a lipid-soluble peptide (cyclosporin) through the blood-brain barrier. J. Neurochem. 45: 1954-1956, 1985.
-
(1985)
J. Neurochem.
, vol.45
, pp. 1954-1956
-
-
Cefalu, W.T.1
Pardridge, W.M.2
-
5
-
-
0025787956
-
Pharmacological profile of inhibition of 2′,7′-bis(2-carboxyethyl)-5(6)-carboxyfluorescein efflux in human H. C. T.-8 intestinal epithelial cells
-
COLLINGTON, G. K., ALLEN, C. N., SIMMONS, N. L. AND HIRST, B. H.: Pharmacological profile of inhibition of 2′,7′-bis(2-carboxyethyl)-5(6)-carboxyfluorescein efflux in human H. C. T.-8 intestinal epithelial cells. Biochem. Pharmacol. 42: S33-38, 1991.
-
(1991)
Biochem. Pharmacol.
, vol.42
-
-
Collington, G.K.1
Allen, C.N.2
Simmons, N.L.3
Hirst, B.H.4
-
6
-
-
0026650170
-
Polarized efflux of 2′,7′-bis(2-carboxyethyl)-5(6)-carboxyfluorescein from cultured epithelial cell monolayers
-
COLLINGTON, G. K., HUNTER, J., ALLEN, C. N., SIMMONS, N. L. A. N. D. HIRST, B. H.: Polarized efflux of 2′,7′-bis(2-carboxyethyl)-5(6)-carboxyfluorescein from cultured epithelial cell monolayers. Biochem. Pharmacol. 44: 417-424, 1992.
-
(1992)
Biochem. Pharmacol.
, vol.44
, pp. 417-424
-
-
Collington, G.K.1
Hunter, J.2
Allen, C.N.3
Simmons, N.L.A.N.D.4
Hirst, B.H.5
-
7
-
-
0020187709
-
Comparision of lipid-mediated blood-brain-barrier penetrability in neonates and adults
-
CORNFORD, E. M., BRAUN, L. D., OLDENDORF, W. H. AND HILL, M. A.: Comparision of lipid-mediated blood-brain-barrier penetrability in neonates and adults. Am. J. Physiol. 243: C161-168, 1982.
-
(1982)
Am. J. Physiol.
, vol.243
-
-
Cornford, E.M.1
Braun, L.D.2
Oldendorf, W.H.3
Hill, M.A.4
-
8
-
-
0021794208
-
The blood-brain barrier, a dynamic regulatory interface
-
CORNFORD, E. M.: The blood-brain barrier, a dynamic regulatory interface. Mol. Physiol., 7: 219-260, 1985.
-
(1985)
Mol. Physiol.
, vol.7
, pp. 219-260
-
-
Cornford, E.M.1
-
9
-
-
0024586119
-
Uptake of leucine and alanine by cultured cerebral capillary endothelial cells
-
HUGHES, C. C. AND LANTOS, P. L.: Uptake of leucine and alanine by cultured cerebral capillary endothelial cells. Brain. Res. 480: 126-132, 1989.
-
(1989)
Brain. Res.
, vol.480
, pp. 126-132
-
-
Hughes, C.C.1
Lantos, P.L.2
-
10
-
-
8644243613
-
Partition coefficient and their uses
-
LEO, A., HANSCH, C. AND ELKINS, D.: Partition coefficient and their uses. Chem. Rev. 71: 525-554, 1971.
-
(1971)
Chem. Rev.
, vol.71
, pp. 525-554
-
-
Leo, A.1
Hansch, C.2
Elkins, D.3
-
11
-
-
0021721682
-
Brain uptake of a food dye, erythrosin B, prevented by plasma protein binding
-
LEVITAN, H., ZIYLAN, Z., SMITH, Q. R., TAKASATO, Y. AND RAPOPORT, S. I.: Brain uptake of a food dye, erythrosin B, prevented by plasma protein binding. Brain Res. 322: 131-134, 1984.
-
(1984)
Brain Res.
, vol.322
, pp. 131-134
-
-
Levitan, H.1
Ziylan, Z.2
Smith, Q.R.3
Takasato, Y.4
Rapoport, S.I.5
-
12
-
-
0019124032
-
Relationship of octanol/water partition coefficient and molecular weight to rat brain capillary permeability
-
LEVIN, V. A.: Relationship of octanol/water partition coefficient and molecular weight to rat brain capillary permeability. J. Med. Chem. 23: 682-684, 1980.
-
(1980)
J. Med. Chem.
, vol.23
, pp. 682-684
-
-
Levin, V.A.1
-
13
-
-
71849104860
-
Protein measurement with Folin phenol reagent
-
LOWRY, O. H., ROSEBROUGH, N. J., FARR, A. L. AND RANDALL, R. J.: Protein measurement with Folin phenol reagent. J. Biol. Chem. 193: 265-275, 1951.
-
(1951)
J. Biol. Chem.
, vol.193
, pp. 265-275
-
-
Lowry, O.H.1
Rosebrough, N.J.2
Farr, A.L.3
Randall, R.J.4
-
14
-
-
0004135189
-
-
Lea & Febiger, Philadelphia
-
MARTIN, A., SWARBRICK, J. AND CAMMARATA, A.: Physical Pharmacy, pp. 399-444, Lea & Febiger, Philadelphia, 1983.
-
(1983)
Physical Pharmacy
, pp. 399-444
-
-
Martin, A.1
Swarbrick, J.2
Cammarata, A.3
-
15
-
-
0014888279
-
Measurement of brain uptake of radiolabeled substances using a tritiated water internal standard
-
OLDENDORF, W. H.: Measurement of brain uptake of radiolabeled substances using a tritiated water internal standard. Brain. Res. 24: 372-376, 1970.
-
(1970)
Brain. Res.
, vol.24
, pp. 372-376
-
-
Oldendorf, W.H.1
-
16
-
-
0038874814
-
+ exchange in gastric glands as measured with a cytoplasmic-trapped, fluorescent pH. indicator
-
+ exchange in gastric glands as measured with a cytoplasmic-trapped, fluorescent pH. indicator. Proc. Natl. Acad. Sci. U.S.A. 81: 7436-7440, 1984.
-
(1984)
Proc. Natl. Acad. Sci. U.S.A.
, vol.81
, pp. 7436-7440
-
-
Paradiso, A.M.1
Tsien, R.Y.2
Machen, T.E.3
-
17
-
-
0022003372
-
Blood-brain barrier transport of butanol and water relative to N-isopropyl-p-iodoamphetamine as the internal reference
-
PARDRIDGE, W. M. AND FIERER, G.: Blood-brain barrier transport of butanol and water relative to N-isopropyl-p-iodoamphetamine as the internal reference. J. Cereb. Blood Flow Metab. 5: 275-281, 1985.
-
(1985)
J. Cereb. Blood Flow Metab.
, vol.5
, pp. 275-281
-
-
Pardridge, W.M.1
Fierer, G.2
-
18
-
-
0022361706
-
Carotid artery injection technique: Bounds for bolus mixing by plasma and by brain
-
PARDRIDGE, W. M., LANDAW, E. M., MILLER, L. P., BRAWN, L. D. AND OLDENDORF, W. H.: Carotid artery injection technique: bounds for bolus mixing by plasma and by brain. J. Cereb. Blood Flow Metab. 5: 576-83, 1985.
-
(1985)
J. Cereb. Blood Flow Metab.
, vol.5
, pp. 576-583
-
-
Pardridge, W.M.1
Landaw, E.M.2
Miller, L.P.3
Brawn, L.D.4
Oldendorf, W.H.5
-
20
-
-
0002468885
-
Brain drug delivery and blood-brain barrier transport
-
PARDRIDGE, W. M.: Brain drug delivery and blood-brain barrier transport. Drug Delivery 1: 83-101, 1993.
-
(1993)
Drug Delivery
, vol.1
, pp. 83-101
-
-
Pardridge, W.M.1
-
21
-
-
0028457129
-
New approaches to drug delivery through the blood-brain barrier
-
PARDRIDGE, W. M.: New approaches to drug delivery through the blood-brain barrier. Trends Biotech, 12: 239-245, 1994.
-
(1994)
Trends Biotech
, vol.12
, pp. 239-245
-
-
Pardridge, W.M.1
-
22
-
-
0028281788
-
In vivo and in vitro blood-brain barrier transport of 3-hydroxy-3-methylglutaryl coenzyme A. (H. M. G.-CoA) reductase inhibitors
-
SAHEKI, A., TERASAKI, T., TAMAI, I. AND TSUJI, A.: In vivo and in vitro blood-brain barrier transport of 3-hydroxy-3-methylglutaryl coenzyme A. (H. M. G.-CoA) reductase inhibitors. Pharm. Res. 11: 305-311, 1994.
-
(1994)
Pharm. Res.
, vol.11
, pp. 305-311
-
-
Saheki, A.1
Terasaki, T.2
Tamai, I.3
Tsuji, A.4
-
23
-
-
0028229150
-
Disruption of the mouse mdrla P-glycoprotein gene leads to a deficiency in the blood-brain barrier and to increased sensitivity to drugs
-
SCHINKEL, A. H., SMIT, J. J., VAN TELLINGEN, O., BEIJNEN, J. H., WAGENAAR, E., VAN DEEMTER, L., MOL, C. A. A. M., VAN DER VALK, M. A., ROBANUS-MAANDAG, E. C., T. E. RIELE, H. P. J., BERNS, A. J. M. AND BORST, P.: Disruption of the mouse mdrla P-glycoprotein gene leads to a deficiency in the blood-brain barrier and to increased sensitivity to drugs. Cell 77: 491-502, 1994.
-
(1994)
Cell
, vol.77
, pp. 491-502
-
-
Schinkel, A.H.1
Smit, J.J.2
Van Tellingen, O.3
Beijnen, J.H.4
Wagenaar, E.5
Van Deemter, L.6
Mol, C.A.A.M.7
Van Der Valk, M.A.8
Robanus-Maandag, E.C.9
T. E. Riele, H.P.J.10
Berns, A.J.M.11
Borst, P.12
-
24
-
-
0000545811
-
An in situ brain perfusion technique to study cerebrovascular transport in the rat
-
TAKASATO, Y., RAPOPORT, S. I. AND SMITH, Q. R.: An in situ brain perfusion technique to study cerebrovascular transport in the rat. Am. J. Physiol. 247: H484-493, 1984.
-
(1984)
Am. J. Physiol.
, vol.247
-
-
Takasato, Y.1
Rapoport, S.I.2
Smith, Q.R.3
-
25
-
-
0027528920
-
Inhibition of the multidrug efflux pump in isolated hepatocyte couplets by immunosuppressants F. K.506 and cyclosporine
-
TAKEGUCHI, N., ICHIMURA, K., KOIKK, M., MATSUI, W., K.A.S.H. I.W.A.G.U.R.A., T. AND KAWAHARA, K.: Inhibition of the multidrug efflux pump in isolated hepatocyte couplets by immunosuppressants F. K.506 and cyclosporine. Transplantation 55: 646-650, 1993.
-
(1993)
Transplantation
, vol.55
, pp. 646-650
-
-
Takeguchi, N.1
Ichimura, K.2
Koikk, M.3
Matsui, W.4
KASHIWAGURA, T.5
Kawahara, K.6
-
26
-
-
0026669192
-
Functional involvement of P-glycoprotein in blood-brain barrier
-
TATSUTA, T., NAITO, M., O. H.-HARA, T., SUGAWARA, I. AND TSURCO, T.: Functional involvement of P-glycoprotein in blood-brain barrier. J. Biol. Chem. 267: 20383-20391, 1992.
-
(1992)
J. Biol. Chem.
, vol.267
, pp. 20383-20391
-
-
Tatsuta, T.1
Naito, M.2
H.-Hara, T.O.3
Sugawara, I.4
Tsurco, T.5
-
27
-
-
0025989302
-
Transport of monocarboxylic acids at the blood-brain barrier: Studies with monolayers of primary cultured bovine brain capillary endothelial cells
-
TERASAKI, T., TAKAKUWA, S., MORITANI, S. AND TSUJI, A.: Transport of monocarboxylic acids at the blood-brain barrier: studies with monolayers of primary cultured bovine brain capillary endothelial cells. J. Pharmacol. Exp. Ther. 258: 932-937, 1991.
-
(1991)
J. Pharmacol. Exp. Ther.
, vol.258
, pp. 932-937
-
-
Terasaki, T.1
Takakuwa, S.2
Moritani, S.3
Tsuji, A.4
-
28
-
-
51249188620
-
The movement of molecules across lipid membranes: A molecular theory
-
TRAUBLE, H.: The movement of molecules across lipid membranes: a molecular theory. J. Membr. Biol. 4: 193-208, 1971.
-
(1971)
J. Membr. Biol.
, vol.4
, pp. 193-208
-
-
Trauble, H.1
-
29
-
-
0017624830
-
Physicochemical properties of β-lactam antibiotics: Oil-water distribution
-
TSUJI, A., KUBO, O., MIYAMOTO, E. AND YAMANA, T.: Physicochemical properties of β-lactam antibiotics: oil-water distribution. J. Pharm. Sci. 66: 1675-1679, 1977.
-
(1977)
J. Pharm. Sci.
, vol.66
, pp. 1675-1679
-
-
Tsuji, A.1
Kubo, O.2
Miyamoto, E.3
Yamana, T.4
-
30
-
-
0026760889
-
P-glycoprotein as the drug efflux pump in primary cultured bovine brain capillary endothelial cells
-
TSUJI, A., TERASAKI, T., TAKABATAKE, Y., TENDA, Y., TAMAI, I., YAMASHIMA, T., MORITANI, S., TSURUO, T. AND YAMASHITA, J.: P-glycoprotein as the drug efflux pump in primary cultured bovine brain capillary endothelial cells. Life Sci. 51: 1427-1437, 1992.
-
(1992)
Life Sci.
, vol.51
, pp. 1427-1437
-
-
Tsuji, A.1
Terasaki, T.2
Takabatake, Y.3
Tenda, Y.4
Tamai, I.5
Yamashima, T.6
Moritani, S.7
Tsuruo, T.8
Yamashita, J.9
-
31
-
-
0027290876
-
Restricted transport of cyclosporin A across the blood-brain barrier by a multidrug transporter, P-glycoprotein
-
TSUJI, A., TAMAI, I., SAKATA, A., TENDA, Y. AND TERASAKI, T.: Restricted transport of cyclosporin A across the blood-brain barrier by a multidrug transporter, P-glycoprotein. Biochem. Pharmacol. 46: 1096-1099, 1993.
-
(1993)
Biochem. Pharmacol.
, vol.46
, pp. 1096-1099
-
-
Tsuji, A.1
Tamai, I.2
Sakata, A.3
Tenda, Y.4
Terasaki, T.5
-
32
-
-
0023752149
-
Carrier-mediated transport of baclofen across monolayers of bovine brain endothelial cells in primary culture
-
VAN BREE, J. B. M. M., AUDUS, K. L. AND BORCHARDT, R. T.: Carrier-mediated transport of baclofen across monolayers of bovine brain endothelial cells in primary culture. Pharm. Res. 5: 369-371, 1988.
-
(1988)
Pharm. Res.
, vol.5
, pp. 369-371
-
-
Van Bree, J.B.M.M.1
Audus, K.L.2
Borchardt, R.T.3
-
33
-
-
0024344357
-
Use of fluorescent dye BCECF to measure intracellular pH. in cortical collecting tubule
-
WEINER, I. D. AND HAMM, L. L.: Use of fluorescent dye BCECF to measure intracellular pH. in cortical collecting tubule. Am. J. Physiol. 256: F957-964, 1989.
-
(1989)
Am. J. Physiol.
, vol.256
-
-
Weiner, I.D.1
Hamm, L.L.2
|