The association of testosterone, sleep, and sexual function in men and women

Brain Research

Volumn 1416, Issue , 2011, Pages 80-104

  Andersen, Monica L ^a   Alvarenga, Tathiana F ^a   Mazaro Costa, Renata ^b   Hachul, Helena C ^a   Tufik, Sergio ^a  

^a FEDERAL UNIVERSITY OF SÃO PAULO   (Brazil)

^b FEDERAL UNIVERSITY OF GOIÁS   (Brazil)

Author keywords

Androgen; Animal model; Climacteric; Erection; Men; Rats; Sexual function; Sleep; Sleep deprivation; Testosterone; Women

Indexed keywords

FOLLITROPIN; LUTEINIZING HORMONE; SEX HORMONE; TESTOSTERONE;

CIRCADIAN RHYTHM; GENDER; HUMAN; NONHUMAN; PRIORITY JOURNAL; REVIEW; SEXUAL BEHAVIOR; SEXUAL DYSFUNCTION; SEXUAL FUNCTION; SLEEP; SLEEP APNEA SYNDROME; SLEEP DEPRIVATION; SLEEP DISORDER; SLEEP DISORDERED BREATHING; TESTOSTERONE BLOOD LEVEL; WAKEFULNESS;

ANIMALS; CIRCADIAN RHYTHM; FEMALE; HUMANS; MALE; SEX FACTORS; SEXUAL BEHAVIOR; SLEEP; SLEEP DISORDERS; TESTOSTERONE;

ANIMALIA; RATTUS;

EID: 80052963234     PISSN: 00068993     EISSN: 18726240     Source Type: Journal    
DOI: 10.1016/j.brainres.2011.07.060     Document Type: Review

References (266)

1. R.T. Abdallah, and J.A. Simon Testosterone therapy in women: its role in the management of hypoactive sexual desire disorder Int. J. Impot. Res. 19 5 2007 458 463 (Pubitemid 47367524)
2. G.E. Abraham, Z.H. Chakmakjian, J.E. Buster, and J.R. Marshall Effect of exogenous conjugated estrogen on plasma gonadotropins and ovarian steroids during the menstrual cycle Obstet. Gynecol. 43 5 1974 676 684
3. A. Agmo Male rat sexual behavior Brain Res. Protoc 1 1997 203 209 (Pubitemid 28281344)
4. D. Ahuja, J.H. Mateika, M.P. Diamond, and M.S. Badr Ventilatory sensitivity to carbon dioxide before and after episodic hypoxia in women treated with testosterone J. Appl. Physiol. 102 5 2007 1832 1838 (Pubitemid 46701951)
5. F. Al-Azzawi, and S. Palacios Hormonal changes during menopause Maturitas 63 2 2009 135 137
6. J.L. Alexander, K. Kotz, L. Dennerstein, S.J. Kutner, K. Wallen, and M. Notelovitz The effects of postmenopausal hormone therapies on female sexual functioning: a review of double-blind, randomized controlled trials Menopause 11 6 Pt 2 2004 749 765
7. J.L. Alexander, L. Dennerstein, H. Burger, and A. Graziottin Testosterone and libido in surgically and naturally menopausal women Womens Health 2 3 2006 459 477
8. T.A. Alvarenga, M.L. Andersen, J. Velazquez-Moctezuma, and S. Tufik Food restriction or sleep deprivation: which exerts a greater influence on the sexual behaviour of male rats? Behav. Brain Res. 202 2 2009 266 271
9. T.A. Alvarenga, M.L. Andersen, and S. Tufik Influence of progesterone on sexual performance in male rats J. Sex. Med. 7 7 2010 2435 2444
10. M.L. Andersen, M. Bignotto, R.B. Machado, and S. Tufik Does paradoxical sleep deprivation and cocaine induce penile erection and ejaculation in old rats? Addict. Biol. 7 3 2002 285 290 (Pubitemid 34848415)
11. M.L. Andersen, M. Bignotto, and S. Tufik Facilitation of ejaculation after methamphetamine administration in paradoxical sleep deprived rats Brain Res. 978 1-2 2003 31 37 (Pubitemid 36780962)
12. M.L. Andersen, M. Bignotto, and S. Tufik Influence of paradoxical sleep deprivation and cocaine on development of spontaneous penile reflexes in rats of different ages Brain Res. 968 1 2003 130 138 (Pubitemid 36315683)
13. M.L. Andersen, M. Bignotto, L.A. Papale, and S. Tufik Age-related effects on genital reflexes induced by paradoxical sleep deprivation and cocaine in rats Exp. Gerontol. 39 2 2004 233 237 (Pubitemid 38169415)
14. M.L. Andersen, M. Bignotto, and S. Tufik Hormone treatment facilitates penile erection in castrated rats after sleep deprivation and cocaine J. Neuroendocrinol. 16 2 2004 154 159 (Pubitemid 38256462)
15. M.L. Andersen, P.J. Martins, V. D'Almeida, M. Bignotto, and S. Tufik Endocrinological and catecholaminergic alterations during sleep deprivation and recovery in male rats J. Sleep Res. 14 1 2005 83 90 (Pubitemid 40403059)
16. M.L. Andersen, L.R. Bittencourt, I.B. Antunes, and S. Tufik Effects of progesterone on sleep: a possible pharmacological treatment for sleep-breathing disorders? Curr. Med. Chem. 13 29 2006 3575 3582 (Pubitemid 44873748)
17. M.L. Andersen, R.C. Martins, T.A. Alvarenga, I.B. Antunes, L.A. Papale, and S. Tufik Progesterone reduces erectile dysfunction in sleep-deprived spontaneously hypertensive rats Reprod. Biol. Endocrinol. 5 2007 7
18. M.L. Andersen, and S. Tufik The effects of testosterone on sleep and sleep-disordered breathing in men: its bidirectional interaction with erectile function Sleep Med. Rev. 12 5 2008 365 379
19. M.L. Andersen, I.B. Antunes, A. Silva, T.A. Alvarenga, E.C. Baracat, and S. Tufik Effects of sleep loss on sleep architecture in Wistar rats: gender-specific rebound sleep Prog. Neuropsychopharmacol. Biol. Psychiatry 32 4 2008 975 983 (Pubitemid 351609232)
20. M.L. Andersen, T.A. Alvarenga, C. Guindalini, J.C. Perry, A. Silva, and A. Zager Paradoxical sleep deprivation influences sexual behavior in female rats J. Sex. Med. 6 8 2009 2162 2172
21. M.L. Andersen, R. Santos-Silva, L.R. Bittencourt, and S. Tufik Prevalence of erectile dysfunction complaints associated with sleep disturbances in Sao Paulo, Brazil: a population-based survey Sleep Med. 11 2010 1019 1024
22. M.L. Andersen, T.A. Alvarenga, D.R. Mazzotti, C. Guindalini, R. Pellegrino, K.F. Barrueco, R. Santos-Silva, L.R. Bittencourt, and S. Tufik Hormonal profile, the PROGINS polymorphism, and erectile dysfunction complaints: data from a population-based survey Fertil. Steril. 95 2 2011 621 624
23. I.B. Antunes, M.L. Andersen, E.C. Baracat, and S. Tufik The effects of paradoxical sleep deprivation on estrous cycles of the female rats Horm. Behav. 49 4 2006 433 440 (Pubitemid 43376092)
24. I.B. Antunes, M.L. Andersen, T.A. Alvarenga, and S. Tufik Effects of paradoxical sleep deprivation on blood parameters associated with cardiovascular risk in intact and ovariectomized rats compared with male rats Behav. Brain Res. 176 2 2007 187 192 (Pubitemid 44911068)
25. R. Armitage, G.J. Emslie, R.F. Hoffmann, J. Rintelmann, and A.J. Rush Delta sleep EEG in depressed adolescent females and healthy controls J. Affect. Disord. 63 1-3 2001 139 148 (Pubitemid 32200508)
26. W. Arlt Dehydroepiandrosterone replacement therapy Semin. Reprod. Med. 22 4 2004 379 388 (Pubitemid 40030087)
27. M. Arteaga, and G. Morali Characteristics of the motor and genital copulatory responses of the male hamster J. Physiol. Paris 91 6 1997 311 316 (Pubitemid 28009320)
28. E. Aserinsky, and N. Kleitman Regularly occurring periods of eye motility, and concomitant phenomena, during sleep Science 118 1953 273 274
29. R.J. Auchus Non-traditional metabolic pathways of adrenal steroids Rev. Endocr. Metab. Disord. 10 1 2009 27 32
30. J. Axelsson, M. Ingre, T. Akerstedt, and U. Holmback Effects of acutely displaced sleep on testosterone J. Clin. Endocrinol. Metab. 90 8 2005 4530 4535 (Pubitemid 41159338)
31. G.A. Bachmann, and S.R. Leiblum Sexuality in sexagenarian women Maturitas 13 1 1991 43 50
32. G. Bachmann, J. Bancroft, G. Braunstein, H. Burger, S. Davis, and L. Dennerstein Female androgen insufficiency: the Princeton consensus statement on definition, classification, and assessment Fertil. Steril. 77 4 2002 660 665 (Pubitemid 34275339)
33. C.J. Bagatell, J.R. Heiman, J.E. Rivier, and W.J. Bremner Effects of endogenous testosterone and estradiol on sexual behavior in normal young men J. Clin. Endocrinol. Metab. 78 3 1994 711 716 (Pubitemid 24083316)
34. J. Bancroft, G. Hammond, and C. Graham Do oral contraceptives produce irreversible effects on women's sexuality? J. Sex. Med. 3 3 2006 567
35. E. Barrett-Connor, T.T. Dam, K. Stone, S.L. Harrison, S. Redline, and E. Orwoll The association of testosterone levels with overall sleep quality, sleep architecture, and sleep-disordered breathing J. Clin. Endocrinol. Metab. 93 7 2008 2602 2609 (Pubitemid 352008526)
36. R. Basson Rethinking low sexual desire in women BJOG 109 4 2002 357 363 (Pubitemid 37338010)
37. F.A. Beach, and R.G. Rabedeau Sexual exhaustion and recovery in the male hamster J. Comp. Physiol. Psychol. 52 1 1959 56 61
38. F.A. Beach, and R.E. Whalen Effects of ejaculation on sexual behavior in the male rat J. Comp. Physiol. Psychol. 52 2 1959 249 254
39. M. Behan, and J.M. Wenninger Sex steroidal hormones and respiratory control Respir. Physiol. Neurobiol. 164 1-2 2008 213 221
40. C. Beyer, G. Morali, F. Naftolin, K. Larsson, and p. Perez Effect of some antiestrogens and aromatase inhibitors on androgen induced sexual behavior in castrated male rats Horm. Behav. 7 3 1976 353 363
41. M. Bialy, M. Rydz, and L. Kaczmarek Precontact 50-kHz vocalizations in male rats during acquisition of sexual experience Behav. Neurosci. 114 5 2000 983 990
42. L.R. Bittencourt, R. Santos-Silva, J.A. Taddei, M.L. Andersen, M.T. de Mello, and S. Tufik Sleep complaints in the adult Brazilian population: a national survey based on screening questions J. Clin. Sleep Med. 5 5 2009 459 463
43. E.O. Bixler, A.N. Vgontzas, H.M. Lin, T. Ten Have, J. Rein, and A. Vela-Bueno Prevalence of sleep-disordered breathing in women: effects of gender Am. J. Respir. Crit. Care Med. 163 3 Pt 1 2001 608 613 (Pubitemid 32230817)
44. E.O. Bixler, A.N. Vgontzas, H.M. Lin, A. Vela-Bueno, and A. Kales Insomnia in central Pennsylvania J. Psychosom. Res. 53 1 2002 589 592
45. M. Bixo, T. Backstrom, B. Winblad, and A. Andersson Estradiol and testosterone in specific regions of the human female brain in different endocrine states J. Steroid Biochem. Mol. Biol. 55 3-4 1995 297 303 (Pubitemid 26017218)
46. C.D. Boethel Sleep and the endocrine system: new associations to old diseases Curr. Opin. Pulm. Med. 8 6 2002 502 505 (Pubitemid 35204701)
47. B.D. Boland, and D.A. Dewsbury Characteristics of sleep following sexual activity and wheel running in male rats Physiol. Behav. 6 2 1971 145 149
48. S.E. Borst, and T. Mulligan Testosterone replacement therapy for older men Clin. Interv. Aging 2 4 2007 561 566
49. R.M. Boyar, R.S. Rosenfeld, S. Kapen, J.W. Finkelstein, H.P. Roffwarg, and E.D. Weitzman Human puberty. Simultaneous augmented secretion of luteinizing hormone and testosterone during sleep J. Clin. Invest. 54 3 1974 609 618
50. T.D. Bradley, and J.S. Floras Obstructive sleep apnoea and its cardiovascular consequences Lancet 373 9657 2009 82 93
51. G.D. Braunstein, D.A. Sundwall, M. Katz, J.L. Shifren, J.E. Buster, and J.A. Simon Safety and efficacy of a testosterone patch for the treatment of hypoactive sexual desire disorder in surgically menopausal women: a randomized, placebo-controlled trial Arch. Intern. Med. 165 14 2005 1582 1589 (Pubitemid 41124151)
52. W.J. Bremner, M.V. Vitiello, and P.N. Prinz Loss of circadian rhythmicity in blood testosterone levels with aging in normal men J. Clin. Endocrinol. Metab. 56 6 1983 1278 1281 (Pubitemid 13055125)
53. B.N. Bunnell, B.D. Boland, and D.A. Dewsbury Copulatory behavior of golden hamsters (Mesocricetus auratus) Behavior 61 1976 180 206
54. H.G. Burger, E.C. Dudley, and D.L. Hopper The endocrinology of the menopausal transition: a cross-sectional study of a population-based sample J. Clin. Endocrinol. Metab. 80 1995 3537 3545
55. J.E. Buster, S.A. Kingsberg, O. Aguirre, C. Brown, J.G. Breaux, and A. Buch Testosterone patch for low sexual desire in surgically menopausal women: a randomized trial Obstet. Gynecol. 105 5 Pt 1 2005 944 952 (Pubitemid 40571010)
56. E. Canchola, E. Monroy, and J. Velazquez-Moctezuma REM sleep deprivation facilitates the estrogen effect on heterotypical sexual behavior in male rats Physiol. Behav. 37 1 1986 33 37 (Pubitemid 16121794)
57. P.A. Cistulli, R.R. Grunstein, and C.E. Sullivan Effect of testosterone administration on upper airway collapsibility during sleep Am. J. Respir. Crit. Care Med. 149 2 Pt 1 1994 530 532 (Pubitemid 24069007)
58. N.A. Collop, D. Adkins, and B.A. Phillips Gender differences in sleep and sleep-disordered breathing Clin. Chest Med. 25 2 2004 257 268 (Pubitemid 38507646)
59. G.B. Colvin, D.I. Whitmoyer, R.D. Lisk, D.O. Walter, and C.H. Sawyer Changes in sleep-wakefulness in female rats during circadian and estrous cycles Brain Res. 7 2 1968 173 181
60. J.F. Couse, S.C. Hewitt, and K.S. Korach 3 ed. Steroid Receptors in the Ovary and Uterus Vol. 15 2006 Elsevier
61. L.G. Dahlof, and K. Larsson Copulatory performances of penile desensitized male rats as a function of prior social and sexual experience Behav. Biol. 24 4 1978 492 497 (Pubitemid 9149323)
62. R.C. Daly, T.P. Su, P.J. Schmidt, M. Pagliaro, D. Pickar, and D.R. Rubinow Neuroendocrine and behavioral effects of high-dose anabolic steroid administration in male normal volunteers Psychoneuroendocrinology 28 3 2003 317 331 (Pubitemid 36164951)
63. J.M. Davidson, and S. Levine Progesterone and heterotypical sexual behaviour in male rats J. Endocrinol. 44 1 1969 129 130
64. J.M. Davidson, M. Kwan, and W.J. Greenleaf Hormonal replacement and sexuality in men Clin. Endocrinol. Metab. 11 3 1982 599 623 (Pubitemid 13249795)
65. S.R. Davis When to suspect androgen deficiency other than at menopause Fertil. Steril. 77 Suppl 4 2002 S68 S71
66. S. Davis, M.A. Papalia, R.J. Norman, S. O'Neill, M. Redelman, and M. Williamson Safety and efficacy of a testosterone metered-dose transdermal spray for treating decreased sexual satisfaction in premenopausal women: a randomized trial Ann. Intern. Med. 148 8 2008 569 577 (Pubitemid 351669130)
67. S.L. Davison, R. Bell, S. Donath, J.G. Montalto, and S.R. Davis Androgen levels in adult females: changes with age, menopause, and oophorectomy J. Clin. Endocrinol. Metab. b90 2005 3847 3853 (Pubitemid 41058142)
68. H. de Boer, L. Verschoor, J. Ruinemans-Koerts, and M. Jansen Letrozole normalizes serum testosterone in severely obese men with hypogonadotropic hypogonadism Diabetes Obes. Metab. 7 3 2005 211 215 (Pubitemid 40542810)
69. W.C. Dement Recent studies on the biological role of rapid eye movement sleep Am. J. Psychiatry 122 4 1965 404 408
70. W. Dement, and N. Kleitman The relation of eye movements during sleep to dream activity: An objective method for the study of dreaming J. Exp. Psych. 53 1957 339 346
71. J.A. Dempsey, and J.B. Skatrud A sleep-induced apneic threshold and its consequences Am. Rev. Respir. Dis. 133 6 1986 1163 1170 (Pubitemid 16090032)
72. L. Dennerstein, E. Dudley, and H. Burger Are changes in sexual functioning during midlife due to aging or menopause? Fertil. Steril. 76 3 2001 456 460
73. L. Dennerstein, J. Randolph, J. Taffe, E. Dudley, and H. Burger Hormones, mood, sexuality, and the menopausal transition Fertil. Steril. 77 4 2002 S42 S48
74. L. Dennerstein, P. Lehert, H.G. Burger, and J.R. Guthrie New findings from non-linear longitudinal modelling of menopausal hormone changes Hum. Reprod. Update 13 6 2007 551 557 (Pubitemid 350018523)
75. P. Diamond, L. Cusan, and J.L. Gomez Metabolic effects of 12 month percutaneous dehydroepiandrosterone replacement therapy in postmenopausal women J. Endocrinol. 150 1996 S43 S50 Suppl.
76. M. Diamond, A. Llacuna, and C. Wong Sex behavior after neonatal progesterone, testosterone, estrogen or antiandrogens Horm. Behav. 4 1-2 1973 73 88
77. M.G. Dow, D.M. Hart, and C.A. Forrest Hormonal treatments of sexual unresponsiveness in postmenopausal women: a comparative study Br. J. Obstet. Gynaecol. 90 4 1983 361 366 (Pubitemid 13128610)
78. K.L. Edinger, and C.A. Frye Sexual experience of male rats influences anxiety-like behavior and androgen levels Physiol. Behav. 92 3 2007 443 453 (Pubitemid 47562042)
79. A.C. Eklof, A.M. Thurelius, M. Garle, A. Rane, and F. Sjoqvist The anti-doping hot-line, a means to capture the abuse of doping agents in the Swedish society and a new service function in clinical pharmacology Eur. J. Clin. Pharmacol. 59 8-9 2003 571 577 (Pubitemid 37494522)
80. M.S. Erskine Solicitation behavior in the estrous female rat: a review Horm. Behav. 23 4 1989 473 502 (Pubitemid 20028502)
81. J.I. Evans, A.M. Maclean, A.A. Ismail, and D. Love Circulating levels of plasma testosterone during sleep Proc. R. Soc. Med. 64 8 1971 841 842
82. B.J. Everitt, and J. Bancroft Of rats and men: the comparative approach to male sexuality 1991
83. J. Fang, and W. Fishbein Sex differences in paradoxical sleep: influences of estrus cycle and ovariectomy Brain Res. 734 1-2 1996 275 285 (Pubitemid 26334056)
84. F. Farabollini, C.L. Di Prisco, and G. Carli Changes in plasma testosterone and in its hypothalamic metabolism following immobility responses in rabbits Physiol. Behav. 20 5 1978 613 618 (Pubitemid 8354391)
85. H.A. Feldman, C. Longcope, C.A. Derby, C.B. Johannes, A.B. Araujo, and A.D. Coviello Age trends in the level of serum testosterone and other hormones in middle-aged men: longitudinal results from the Massachusetts male aging study J. Clin. Endocrinol. Metab. 87 2 2002 589 598 (Pubitemid 34158223)
86. J. Ferguson, and W. Dement The behavioral effects of amphetamine on REM deprived rats J. Psychiatr. Res. 7 2 1969 111 118
87. L. Ferini-Strambi, A. Oldani, M. Zucconi, V. Castronovo, F. Montorsi, and P. Rigatti Sleep-related painful erections: clinical and polysomnographic features J. Sleep Res. 5 3 1996 195 197 (Pubitemid 26380249)
88. J.S. Finkelstein, L.S. O'Dea, R.W. Whitcomb, and W.F. Crowley Jr. Sex steroid control of gonadotropin secretion in the human male. II. Effects of estradiol administration in normal and gonadotropin-releasing hormone-deficient men J. Clin. Endocrinol. Metab. 73 3 1991 621 628 (Pubitemid 21921917)
89. R.B. Fogel, A. Malhotra, G. Pillar, S.D. Pittman, A. Dunaif, and D.P. White Increased prevalence of obstructive sleep apnea syndrome in obese women with polycystic ovary syndrome J. Clin. Endocrinol. Metab. 86 3 2001 1175 1180 (Pubitemid 32323001)
90. R.H. Fogle, F.Z. Stanczyk, X. Zhang, and R.J. Paulson Ovarian androgen production in postmenopausal women J. Clin. Endocrinol. Metab. 92 8 2007 3040 3043 (Pubitemid 47236368)
91. T.R. Forbes A A. Berthold and the first endocrine experiment: Some speculation as to its origin. Bulletin History Medicine 23 1949 263 267
92. A.I. Frankel Hormone release during computer-monitored sexual behavior in mature and aged male rats Horm. Behav. 15 3 1981 312 320 (Pubitemid 11057749)
93. M.E. Freeman Neuroendocrine control of the ovarian cycle of the rat Knobil and Neill's: Physiology of Reproduction 3 ed. 2006
94. R. Frussa-Filho, M.T. Goncalves, M.L. Andersen, N.P. de Araujo, C.C. Chinen, and S. Tufik Paradoxical sleep deprivation potentiates amphetamine-induced behavioural sensitization by increasing its conditioned component Brain Res. 1003 1-2 2004 188 193 (Pubitemid 38317100)
95. D.F. Fukushiro, M.B. Calzavara, T.F. Trombin, G.B. Lopez, V.C. Abilio, and M.L. Andersen Effects of environmental enrichment and paradoxical sleep deprivation on open-field behavior of amphetamine-treated mice Physiol. Behav. 92 4 2007 773 779 (Pubitemid 350016139)
96. A. Gambineri, C. Pelusi, and R. Pasquali Testosterone levels in obese male patients with obstructive sleep apnea syndrome: relation to oxygen desaturation, body weight, fat distribution and the metabolic parameters J. Endocrinol. Invest. 26 6 2003 493 498 (Pubitemid 36998695)
97. A.D. Genazzani, M. Stomati, F. Bernardi, M. Pieri, L. Rovati, and A.R. Genazzani Long-term low-dose dehydroepiandrosterone oral supplementation in early and late postmenopausal women modulates endocrine parameters and synthesis of neuroactive steroids Fertil. Steril. 80 6 2003 1495 1501 (Pubitemid 37532468)
98. A.D. Genazzani, C. Lanzoni, and A.R. Genazzani Might DHEA be considered a beneficial replacement therapy in the elderly? Drugs Aging 24 3 2007 173 185 (Pubitemid 46457022)
99. D.C. Gerardin, O.C. Pereira, W.G. Kempinas, J.C. Florio, E.G. Moreira, and M.M. Bernardi Sexual behavior, neuroendocrine, and neurochemical aspects in male rats exposed prenatally to stress Physiol. Behav. 84 1 2005 97 104 (Pubitemid 40092070)
100. U. Goebelsmann, J.J. Arce, I.H. Thorneycroft, and D.R. Mishell Jr. Serum testosterone concentrations in women throughout the menstrual cycle and following HCG administration Am. J. Obstet. Gynecol. 119 4 1974 445 452
101. V.H. Goh, and T.Y. Tong Sleep, sex steroid hormones, sexual activities, and aging in Asian men J. Androl. 31 2 2009 131 137
102. Y.H. Goh, I. Mark, and W.E. Fee Jr. Quality of life 17 to 20 years after uvulopalatopharyngoplasty Laryngoscope 117 3 2007 503 506 (Pubitemid 46407762)
103. M.A. Goncalves, C. Guilleminault, E. Ramos, A. Palha, and T. Paiva Erectile dysfunction, obstructive sleep apnea syndrome and nasal CPAP treatment Sleep Med. 6 4 2005 333 339 (Pubitemid 40867824)
104. L. Gooren Androgen deficiency in the aging male: benefits and risks of androgen supplementation J. Steroid Biochem. Mol. Biol. 85 2-5 2003 349 355 (Pubitemid 37011109)
105. D. Gozal, J.M. Daniel, and G.P. Dohanich Behavioral and anatomical correlates of chronic episodic hypoxia during sleep in the rat J. Neurosci. 21 7 2001 2442 2450 (Pubitemid 32240541)
106. V.J. Grant, and J.T. France Dominance and testosterone in women Biol. Psychol. 58 1 2001 41 47 (Pubitemid 32685502)
107. P.B. Gray, A.B. Singh, L.J. Woodhouse, T.W. Storer, R. Casaburi, and J. Dzekov Dose-dependent effects of testosterone on sexual function, mood, and visuospatial cognition in older men J. Clin. Endocrinol. Metab. 90 7 2005 3838 3846 (Pubitemid 41058141)
108. A. Graziottin, and S.R. Leiblum Biological and psychosocial pathophysiology of female sexual dysfunction during the menopausal transition J. Sex. Med. 2 Suppl 3 2005 133 145 (Pubitemid 41727406)
109. R.R. Grunstein, D.J. Handelsman, S.J. Lawrence, C. Blackwell, I.D. Caterson, and C.E. Sullivan Neuroendocrine dysfunction in sleep apnea: reversal by continuous positive airways pressure therapy J. Clin. Endocrinol. Metab. 68 2 1989 352 358 (Pubitemid 19052876)
110. C. Guilleminault, F.L. Eldridge, A. Tilkian, F.B. Simmons, and W.C. Dement Sleep apnea syndrome due to upper airway obstruction: a review of 25 cases Arch. Intern. Med. 137 3 1977 296 300 (Pubitemid 9041304)
111. H. Hachul de Campos, L.C. Brandao, V. D'Almeida, B.H. Grego, L.R. Bittencourt, and S. Tufik Sleep disturbances, oxidative stress and cardiovascular risk parameters in postmenopausal women complaining of insomnia Climacteric 9 4 2006 312 319 (Pubitemid 44147852)
112. H. Hachul, L.R. Bittencourt, M.L. Andersen, M.A. Haidar, E.C. Baracat, and S. Tufik Effects of hormone therapy with estrogen and/or progesterone on sleep pattern in postmenopausal women Int. J. Gynaecol. Obstet. 103 3 2008 207 212
113. H. Hachul, L.R. Bittencourt, J.M. Soares Jr., S. Tufik, and E.C. Baracat Sleep in post-menopausal women: differences between early and late post-menopause Eur. J. Obstet. Gynecol. Reprod. Biol. 145 1 2009 81 84
114. H. Hachul, M.L. Andersen, L.R. Bittencourt, R. Santos-Silva, S.G. Conway, and S. Tufik Does the reproductive cycle influence sleep patterns in women with sleep complaints? Climacteric 13 6 2010 594 603
115. H. Hachul, L.C. Brandão, V. D'Almeida, L.R. Bittencourt, E.C. Baracat, and S. Tufik Isoflavones decrease insomnia in postmenopause Menopause 18 2 2011 178 184
116. M.M. Hadjimarkou, R. Benham, J.M. Schwarz, M.K. Holder, and J.A. Mong Estradiol suppresses rapid eye movement sleep and activation of sleep-active neurons in the ventrolateral preoptic area Eur. J. Neurosci. 27 7 2008 1780 1792 (Pubitemid 351473584)
117. J.E. Hall, J.P. Sullivan, and G.S. Richardson Brief wake episodes modulate sleep-inhibited luteinizing hormone secretion in the early follicular phase J. Clin. Endocrinol. Metab. 90 4 2005 2050 2055 (Pubitemid 40586238)
118. A.O. Hammoud, M. Gibson, C.M. Peterson, B.D. Hamilton, and D.T. Carrell Obesity and male reproductive potential J. Androl. 27 5 2006 619 626 (Pubitemid 44520801)
119. A.O. Hammoud, M. Gibson, C.M. Peterson, A.W. Meikle, and D.T. Carrell Impact of male obesity on infertility: a critical review of the current literature Fertil. Steril. 90 4 2008 897 904
120. H.M. Hanafy Testosterone therapy and obstructive sleep apnea: is there a real connection? J. Sex. Med. 4 5 2007 1241 1246 (Pubitemid 47337667)
121. J.A. Harris, J.P. Rushton, E. Hampson, and D.N. Jackson Salivary testosterone and self-report aggressive and pro-social personality characteristics in men and women Aggress. Behav. 22 1996 321 331 (Pubitemid 126332489)
122. R.D. Hayes Circular and linear modeling of female sexual desire and arousal J. Sex Res. 48 2-3 2011 130 141
123. C.L. Henley, A.A. Nunez, and L.G. Clemens Exogenous androgen during development alters adult partner preference and mating behavior in gonadally intact male rats Horm. Behav. 57 4-5 2010 488 495
124. M. Hirshkowitz, and M.H. Schmidt Sleep-related erections: clinical perspectives and neural mechanisms Sleep Med. Rev. 9 4 2005 311 329 (Pubitemid 40982499)
125. M. Hirshkowitz, C.A. Moore, S. O'Connor, M. Bellamy, and G.R. Cunningham Androgen and sleep-related erections J. Psychosom. Res. 42 6 1997 541 546 (Pubitemid 27299948)
126. Z. Hubayter, and J.A. Simon Testosterone therapy for sexual dysfunction in postmenopausal women Climacteric 11 3 2008 181 191
127. E.M. Hull, and J.M. Dominguez Sexual behavior in male rodents Horm. Behav. 52 1 2007 45 55 (Pubitemid 46809862)
128. U.W. Huck, R.D. Lisk, and E.J. Parente Effect of the interintromission interval on lordotic response and attack latency in golden hamsters (Mesocricetus auratus) J. Comp. Psychol. 102 4 1988 388 391
129. G.S. Hwang, C.Y. Jian, T.J. Chen, S.T. Chen, and S.W. Wang Effects of hypoxia on testosterone release in rat Leydig cells Am. J. Physiol. Endocrinol. Metab. 297 5 2009 E1039 E1045
130. G. Jackson Prevention of cardiovascular disease by the early identification of erectile dysfunction Int. J. Impot. Res. Suppl. 2 2008 S9 S14
131. J.T. Jankowski, A.D. Seftel, and K.P. Strohl Erectile dysfunction and sleep related disorders J. Urol. 179 3 2008 837 841
132. A. Jimenez-Anguiano, M. Arteaga-Silva, and J. Velazquez-Moctezuma Masculine sexual activity affects slow wave sleep in Golden hamsters Brain Res. Bull. 59 6 2003 429 432 (Pubitemid 36173596)
133. M.W. Johnson, A.M. Anch, and J.E. Remmers Induction of the obstructive sleep apnea syndrome in a woman by exogenous androgen administration Am. Rev. Respir. Dis. 129 6 1984 1023 1025 (Pubitemid 14111768)
134. I. Karacan, and M. Karatas Erectile dysfunction in sleep apnea and response to CPAP J. Sex Marital Ther. 21 4 1995 239 247
135. I.N. Karatsoreos, A. Wang, J. Sasanian, and R. Silver A role for androgens in regulating circadian behavior and the suprachiasmatic nucleus Endocrinology 148 11 2007 5487 5495 (Pubitemid 350012648)
136. H. Kleinlogel Analysis of the vigilance stages in the rat by fast Fourier transformation Neuropsychobiology 23 4 1990 197 204
137. H. Kleinlogel, G. Scholtysik, and A.C. Sayers Effects of clonidine and BS 100-141 on the EEG sleep pattern in rats Eur. J. Pharmacol. 33 1 1975 159 163
138. M. Kotani, M. Detheux, A. Vandenbogaerde, D. Communi, J.M. Vanderwinden, and E. Le Poul The metastasis suppressor gene KiSS-1 encodes kisspeptins, the natural ligands of the orphan G protein-coupled receptor GPR54 J. Biol. Chem. 276 37 2001 34631 34636
139. L.C. Krey, and M.Y. McGinnis Time-courses of the appearance/disappearance of nuclear androgen + receptor complexes in the brain and adenohypophysis following testosterone administration/withdrawal to castrated male rats: relationships with gonadotropin secretion J. Steroid Biochem. 35 3-4 1990 403 408 (Pubitemid 20120433)
140. F. Labrie, P. Diamond, L. Cusan, J.L. Gomez, A. Bélanger, and B. Candas Effect of 12-month dehydroepiandrosterone replacement therapy on bone, vagina, and endometrium in postmenopausal women J. Clin. Endocrinol. Metab. 82 10 1997 3498 3505 (Pubitemid 27419111)
141. K.M. Lakshman, and S. Basaria Safety and efficacy of testosterone gel in the treatment of male hypogonadism Clin. Interv. Aging 4 2009 397 412
142. J. Laszy, and A. Sarkadi Hypoxia-induced sleep disturbance in rats Sleep 13 3 1990 205 217 (Pubitemid 20179943)
143. R. Leproult, and E. Van Cauter Role of sleep and sleep loss in hormonal release and metabolism Endocr. Dev. 17 2010 11 21
144. E. Lindberg, C. Janson, T. Gislason, E. Bjornsson, J. Hetta, and G. Boman Sleep disturbances in a young adult population: can gender differences be explained by differences in psychological status? Sleep 20 6 1997 381 387 (Pubitemid 27387897)
145. P.Y. Liu, I.D. Caterson, R.R. Grunstein, and D.J. Handelsman Androgens, obesity, and sleep-disordered breathing in men Endocrinol. Metab. Clin. North Am. 36 2 2007 349 363 (Pubitemid 46817883)
146. P.Y. Liu, R.S. Swerdloff, and C. Wang Relative testosterone deficiency in older men: clinical definition and presentation Endocrinol. Metab. Clin. North Am. 34 4 2005 957 972 x (Pubitemid 41677407)
147. P.Y. Liu, B. Yee, S.M. Wishart, M. Jimenez, D.G. Jung, and R.R. Grunstein The short-term effects of high-dose testosterone on sleep, breathing, and function in older men J. Clin. Endocrinol. Metab. 88 8 2003 3605 3613 (Pubitemid 37034502)
148. R.A. Lobo Androgens in postmenopausal women: production, possible role, and replacement options Obstet. Gynecol. Surv. 56 6 2001 361 376 (Pubitemid 32520648)
149. R. Luboshitzky, P. Herer, M. Levi, Z. Shen-Orr, and P. Lavie Relationship between rapid eye movement sleep and testosterone secretion in normal men J. Androl. 20 6 1999 731 737
150. R. Luboshitzky, L. Lavie, Z. Shen-Orr, and P. Herer Altered luteinizing hormone and testosterone secretion in middle-aged obese men with obstructive sleep apnea Obes. Res. 13 4 2005 780 786
151. R. Luboshitzky, L. Lavie, Z. Shen-Orr, and P. Lavie Pituitary-gonadal function in men with obstructive sleep apnea. The effect of continuous positive airways pressure treatment Neuro Endocrinol. Lett. 24 6 2003 463 467 (Pubitemid 38035098)
152. R. Luboshitzky, Z. Shen-Orr, and P. Herer Seminal plasma melatonin and gonadal steroids concentrations in normal men Arch. Androl. 48 3 2002 225 232 (Pubitemid 34442067)
153. R. Luboshitzky, Z. Zabari, Z. Shen-Orr, P. Herer, and P. Lavie Disruption of the nocturnal testosterone rhythm by sleep fragmentation in normal men J. Clin. Endocrinol. Metab. 86 3 2001 1134 1139 (Pubitemid 32322993)
154. V. Luu-The, I. Dufort, G. Pelletier, and F. Labrie Type 5 17beta-hydroxysteroid dehydrogenase: its role in the formation of androgens in women Mol. Cell. Endocrinol. 171 1-2 2001 77 82 (Pubitemid 32098200)
155. D. Margel, R. Tal, P.M. Livne, and G. Pillar Predictors of erectile function improvement in obstructive sleep apnea patients with long-term CPAP treatment Int. J. Impot. Res. 17 2 2005 186 190 (Pubitemid 40434595)
156. C. Martel, M.H. Melner, D. Gagné, J. Simard, and F. Labrie Widespread tissue distribution of steroid sulfatase, 3 beta-hydroxysteroid dehydrogenase/delta 5-delta 4 isomerase (3 beta-HSD), 17 beta-HSD 5 alpha-reductase and aromatase activities in the rhesus monkey Mol. Cell. Endocrinol. 104 1 1994 103 111
157. M.K. McClintock Estrous synchrony: modulation of ovarian cycle length by female pheromones Physiol. Behav. 32 5 1984 701 705 (Pubitemid 14096994)
158. T.E. McGill Studies of the Sexual Behavior of Male Laboratory Mice: Effects of Genotype, Recovery of Sex Drive, and Theory Vol. 76 1965 Wiley New York: F. A. Beach
159. M.Y. McGinnis, M.C. Mirth, A.F. Zebrowski, and R.M. Dreifuss Critical exposure time for androgen activation of male sexual behavior in rats Physiol. Behav. 46 2 1989 159 165 (Pubitemid 19244072)
160. P. Meerlo The effect of social stimuli on the accumulation of sleep debt and need for recovery: does copulatory activity increase slow-wave sleep? J. Sleep Res. 12 2 2003 171 172 (Pubitemid 36628376)
161. P. Meerlo, and F.W. Turek Effects of social stimuli on sleep in mice: non-rapid-eye-movement (NREM) sleep is promoted by aggressive interaction but not by sexual interaction Brain Res. 907 1-2 2001 84 92 (Pubitemid 32595514)
162. R.L. Meisel, and B.D. Sachs The Physiology of Male Sexual Behavior Vol. 2 1994 Raven Press New York
163. C.M. Meston, E. Hull, R.J. Levin, and M. Sipski Disorders of orgasm in women J. Sex. Med. 1 1 2004 66 68 (Pubitemid 40424668)
164. W.L. Miller Androgen synthesis in adrenarche Rev. Endocr. Metab. Disord. 10 1 2009 3 17
165. A.D. Mooradian, J.E. Morley, and S.G. Korenman Biological actions of androgens Endocr. Rev. 8 1 1987 1 28
166. B. Morden, R. Conner, G. Mitchell, W. Dement, and S. Levine Effects of rapid eye movement (REM) sleep deprivation on shock-induced fighting Physiol. Behav. 3 3 1968 425 432
167. A.I. Muir, L. Chamberlain, N.A. Elshourbagy, D. Michalovich, D.J. Moore, and A. Calamari AXOR12, a novel human G protein-coupled receptor, activated by the peptide KiSS-1 J. Biol. Chem. 276 31 2001 28969 28975
168. National Disease and Therapeutic Index IMS Health 2003
169. V.M. Navarro, J.M. Castellano, R. Fernandez-Fernandez, M.L. Barreiro, J. Roa, and J.E. Sanchez-Criado Developmental and hormonally regulated messenger ribonucleic acid expression of KiSS-1 and its putative receptor, GPR54, in rat hypothalamus and potent luteinizing hormone-releasing activity of KiSS-1 peptide Endocrinology 145 10 2004 4565 4574 (Pubitemid 39281449)
170. E. Nieschlag, and A.A. Ismail Diurnal variations of plasma testosterone in normal and pathological conditions as measured by the technique of competitive protein binding J. Endocrinol. 46 2 1970 3 4
171. L.H. Nobrega, G.D. Azevedo, J.G. Lima, R.A. Ferriani, P.M. Spritzer, and M.F. Sa Analysis of testosterone pulsatility in women with ovulatory menstrual cycles Arq. Bras. Endocrinol. Metabol. 53 8 2009 1040 1046
172. L. O'Donnell, S.J. Meachem, P.G. Stanton, and R.I. McLachlan 3 ed. Endocrine Regulation of Spermatogenesis Vol. 21 2006 Elsevier
173. M.M. Ohayon, P.L. Morselli, and C. Guilleminault Prevalence of nightmares and their relationship to psychopathology and daytime functioning in insomnia subjects Sleep 20 5 1997 340 348 (Pubitemid 27318495)
174. P.K. Opstad The hypothalamo-pituitary regulation of androgen secretion in young men after prolonged physical stress combined with energy and sleep deprivation Acta Endocrinol. (Copenh) 127 3 1992 231 236
175. I. Oswald Sleep mechanisms: recent advances Proc. R. Soc. Med. 55 1962 910 912
176. A.B. Parkinson, and N.A. Evans Anabolic androgenic steroids: a survey of 500 users Med. Sci. Sports Exerc. 38 4 2006 644 651
177. R. Pasquali Obesity and androgens: facts and perspectives Fertil. Steril. 85 5 2006 1319 1340
178. C.L. Patti, K.A. Zanin, L. Sanday, S.R. Kameda, L. Fernandes-Santos, H.A. Fernandes, M.L. Andersen, S. Tufik, and R. Frussa-Filho Effects of sleep deprivation on memory in mice: role of state-dependent learning Sleep 33 12 2010 1669 1679
179. K.N. Paul, C. Dugovic, F.W. Turek, and A.D. Laposky Diurnal sex differences in the sleep-wake cycle of mice are dependent on gonadal function Sleep 29 9 2006 1211 1223 (Pubitemid 44484815)
180. K.N. Paul, A.D. Laposky, and F.W. Turek Reproductive hormone replacement alters sleep in mice Neurosci. Lett. 463 3 2009 239 243
181. P.D. Penev Association between sleep and morning testosterone levels in older men Sleep 30 4 2007 427 432 (Pubitemid 46668699)
182. O.C. Pereira, M.M. Bernardi, and D.C. Gerardin Could neonatal testosterone replacement prevent alterations induced by prenatal stress in male rats? Life Sci. 78 24 2006 2767 2771
183. P. Perimenis, K. Karkoulias, A. Konstantinopoulos, M. Alchanatis, P.P. Perimeni, and A. Athanasopoulos The impact of long-term conventional treatment for overlap syndrome (obstructive sleep apnea and chronic obstructive pulmonary disease) on concurrent erectile dysfunction Respir. Med. 101 2 2007 210 216 (Pubitemid 46075985)
184. H. Persky, L. Dreisbach, W.R. Miller, C.P. O'Brien, M.A. Khan, and H.I. Lief The relation of plasma androgen levels to sexual behaviors and attitudes of women Psychosom. Med. 44 4 1982 305 319 (Pubitemid 12034612)
185. H. Persky, H.I. Lief, D. Strauss, W.R. Miller, and C.P. O'Brien Plasma testosterone level and sexual behavior of couples Arch. Sex. Behav. 7 3 1978 157 173 (Pubitemid 10091111)
186. J.C. Perry, and M.J. Decker Hypoxia: introduction of mechanisms and consequences Animal Models as Tool in Ethical Biomedical Research 2010 211 224
187. J.G. Pfaus Frank A. Beach award. Homologies of animal and human sexual behaviors Horm. Behav. 30 3 1996 187 200 (Pubitemid 26356906)
188. J.G. Pfaus, and M.F. Wilkins A novel environment disrupts copulation in sexually naive but not experienced male rats: reversal with naloxone Physiol. Behav. 57 6 1995 1045 1049
189. B.E. Piacsek, and M.W. Hostetter Neonatal androgenization in the male rat: evidence for central and peripheral defects Biol. Reprod. 30 2 1984 344 351 (Pubitemid 14144459)
190. M.L. Pires, A.A. Benedito-Silva, M.T. Mello, G. Pompeia Sdel, and S. Tufik Sleep habits and complaints of adults in the city of Sao Paulo, Brazil, in 1987 and 1995 Braz. J. Med. Biol. Res. 40 11 2007 1505 1515 (Pubitemid 350302863)
191. T.M. Plant, and S.F. Witchel 3 ed. Puberty in Nonhuman Primates and Humans Vol. 40 2006 Elsevier
192. S.R. Plymate, J.S. Tenover, and W.J. Bremner Circadian variation in testosterone, sex hormone-binding globulin, and calculated non-sex hormone-binding globulin bound testosterone in healthy young and elderly men J. Androl. 10 5 1989 366 371 (Pubitemid 19266891)
193. E.I. Pollak, and B.D. Sachs Masculine sexual behavior and morphology: paradoxical effects of perinatal androgen treatment in male and female rats Behav. Biol. 13 4 1975 401 411
194. A. Rajkovic, S.A. Pangas, and M.M. Matzuk 3 ed. Follicular Development: Mouse, Sheep, and Human Models Vol. 10 2006 Elsevier
195. J.A. Resko, and K.B. Eik-nes Diurnal testosterone levels in peripheral plasma of human male subjects J. Clin. Endocrinol. Metab. 26 5 1966 573 576
196. R.A. Rey, M. Musse, M. Venara, and H.E. Chemes Ontogeny of the androgen receptor expression in the fetal and postnatal testis: its relevance on Sertoli cell maturation and the onset of adult spermatogenesis Microsc. Res. Tech. 72 11 2009 787 795
197. S. Roizenblatt, F. Fregni, R. Gimenez, T. Wetzel, S.P. Rigonatti, and S. Tufik Site-specific effects of transcranial direct current stimulation on sleep and pain in fibromyalgia: a randomized, sham-controlled study Pain Pract. 7 4 2007 297 306 (Pubitemid 350142298)
198. C.E. Roselli, J.E. Thornton, and K.C. Chambers Age-related deficits in brain estrogen receptors and sexual behavior of male rats Behav. Neurosci. 107 1 1993 202 209 (Pubitemid 23187270)
199. R. Rubens, M. Dhont, and A. Vermeulen Further studies on Leydig cell function in old age J. Clin. Endocrinol. Metab. 39 1 1974 40 45
200. R.T. Rubin, and R.E. Poland Synchronies between sleep and endocrine rhythms in man and their statistical evaluation Psychoneuroendocrinology 1 3 1976 281 290
201. T. Saaresranta, and O. Polo Hormones and breathing Chest 122 6 2002 2165 2182 (Pubitemid 36051157)
202. J.D. Santamaria, J.C. Prior, and J.A. Fleetham Reversible reproductive dysfunction in men with obstructive sleep apnoea Clin. Endocrinol. (Oxf) 28 5 1988 461 470
203. R.J. Santen, and C.W. Bardin Episodic luteinizing hormone secretion in man. Pulse analysis, clinical interpretation, physiologic mechanisms J. Clin. Invest. 52 10 1973 2617 2628
204. R. Santulli, R.L. Sprando, C.A. Awoniyi, L.L. Ewing, and B.R. Zirkin To what extent can spermatogenesis be maintained in the hypophysectomized adult rat testis with exogenously administered testosterone? Endocrinology 126 1 1990 95 101 (Pubitemid 20037130)
205. R.C. Schiavi, D. White, and J. Mandeli Pituitary-gonadal function during sleep in healthy aging men Psychoneuroendocrinology 17 6 1992 599 609 (Pubitemid 23043122)
206. R.C. Schiavi, D. White, J. Mandeli, and A.C. Levine Effect of testosterone administration on sexual behavior and mood in men with erectile dysfunction Arch. Sex. Behav. 26 3 1997 231 241 (Pubitemid 27188130)
207. A. Schwenkhagen Hormonal changes in menopause and implications on sexual health J. Sex. Med. 4 Suppl 3 2007 220 226 (Pubitemid 46372030)
208. B. Schwierin, A.A. Borbely, and I. Tobler Sleep homeostasis in the female rat during the estrous cycle Brain Res. 811 1-2 1998 96 104 (Pubitemid 29003369)
209. S.B. Seminara, M.J. Dipietro, S. Ramaswamy, W.F. Crowley Jr., and T.M. Plant Continuous human metastin 45-54 infusion desensitizes G protein-coupled receptor 54-induced gonadotropin-releasing hormone release monitored indirectly in the juvenile male Rhesus monkey (Macaca mulatta): a finding with therapeutic implications Endocrinology 147 5 2006 2122 2126
210. P.A. Semple, A. Graham, Y. Malcolm, G.H. Beastall, and W.S. Watson Hypoxia, depression of testosterone, and impotence in pickwickian syndrome reversed by weight reduction Br. Med. J. (Clin. Res. Ed) 289 6448 1984 801 802 (Pubitemid 14009923)
211. E. Shahar, S. Redline, T. Young, L.L. Boland, C.M. Baldwin, and F.J. Nieto Hormone replacement therapy and sleep-disordered breathing Am. J. Respir. Crit. Care Med. 167 9 2003 1186 1192 (Pubitemid 36555089)
212. J.L. Shifren, S.R. Davis, M. Moreau, A. Waldbaum, C. Bouchard, L. DeRogatis, C. Derzko, P. Bearnson, N. Kakos, S. O'Neill, S. Levine, K. Wekselman, A. Buch, C. Rodenberg, and R. Kroll Testosterone patch for the treatment of hypoactive sexual desire disorder in naturally menopausal women: results from the INTIMATE NM1 Study Menopause 13 2006 770 779
213. A. Silva, M.L. Andersen, M.T. De Mello, L.R. Bittencourt, D. Peruzzo, and S. Tufik Gender and age differences in polysomnography findings and sleep complaints of patients referred to a sleep laboratory Braz. J. Med. Biol. Res. 41 12 2008 1067 1075
214. H. Simmer Zur Erinnerung an den hundertsten Todestag des Begrunders der experimentellen 1961
215. J. Simon, G. Braunstein, L. Nachtigall, W. Utian, M. Katz, and S. Miller Testosterone patch increases sexual activity and desire in surgically menopausal women with hypoactive sexual desire disorder J. Clin. Endocrinol. Metab. 90 9 2005 5226 5233 (Pubitemid 41262278)
216. J.L. Shifren, S.R. Davis, M. Moreau, A. Waldbaum, C. Bouchard, L. DeRogatis, C. Derzko, P. Bearnson, N. Kakos, S. O'Neill, S. Levine, K. Wekselman, A. Buch, C. Rodenberg, and R. Kroll Testosterone patch for the treatment of hypoactive sexual desire disorder in naturally menopausal women: results from the INTIMATE NM1 Study Menopause 13 5 2006 770 779
217. J.T. Smith, M.J. Cunningham, E.F. Rissman, D.K. Clifton, and R.A. Steiner Regulation of Kiss1 gene expression in the brain of the female mouse Endocrinology 146 9 2005 3686 3692 (Pubitemid 41175732)
218. P. Sodersten, and K. Larsson Lordosis behavior and mounting behavior in male rats: effects of castration and treatment with estradiol benzoate or testosterone propionate Physiol. Behav. 14 2 1975 159 164
219. G.K. Soukhova-O'Hare, R.V. Ortines, Y. Gu, A.D. Nozdrachev, S.D. Prabhu, and D. Gozal Postnatal intermittent hypoxia and developmental programming of hypertension in spontaneously hypertensive rats: the role of reactive oxygen species and L-Ca2+ channels Hypertension 52 1 2008 156 162
220. M.R. Soules, S. Sherman, E. Parrott, R. Rebar, N. Santoro, W. Utian, and N. Woods Stages of Reproductive Aging Workshop (STRAW) J. Womens Health Gend. Based Med. 10 9 2001 843 848 (Pubitemid 33138765)
221. M.F. Sowers, H. Zheng, H.M. Kravitz, K. Matthews, J.T. Bromberger, and E.B. Gold Sex steroid hormone profiles are related to sleep measures from polysomnography and the Pittsburgh Sleep Quality Index Sleep 31 10 2008 1339 1349
222. K. Spiegel, R. Leproult, and E. Van Cauter Impact of sleep debt on metabolic and endocrine function Lancet 354 9188 1999 1435 1439 (Pubitemid 29494756)
223. D.A. Stewart, R.R. Grunstein, M. Berthon-Jones, D.J. Handelsman, and C.E. Sullivan Androgen blockade does not affect sleep-disordered breathing or chemosensitivity in men with obstructive sleep apnea Am. Rev. Respir. Dis. 146 6 1992 1389 1393
224. D.M. Stocco, and M.J. McPhaul 3 ed. Physiology of Testicular Steroidogenesis Vol. 20 2006 Elsevier
225. M. Stomati, P. Monteleone, E. Casarosa, B. Quirici, S. Puccetti, F. Bernardi, A.D. Genazzani, L. Rovati, M. Luisi, and A.R. Genazzani Six-month oral dehydroepiandrosterone supplementation in early and late postmenopause Gynecol. Endocrinol. 14 5 2000 342 363
226. A. Sura, D.H. Overstreet, and L. Marson Selectively bred male rat lines differ in naive and experienced sexual behavior Physiol. Behav. 72 1-2 2001 13 20 (Pubitemid 32184788)
227. F. Talih, O. Fattal, and D. Malone Jr. Anabolic steroid abuse: psychiatric and physical costs Cleve. Clin. J. Med. 74 5 2007 341 344 346, 349-352.
228. K. Tatsumi, B. Hannhart, C.K. Pickett, J.V. Weil, and L.G. Moore Effects of testosterone on hypoxic ventilatory and carotid body neural responsiveness Am. J. Respir. Crit. Care Med. 149 5 1994 1248 1253 (Pubitemid 24147067)
229. C.M. Tenk, H. Wilson, Q. Zhang, K.K. Pitchers, and L.M. Coolen Sexual reward in male rats: effects of sexual experience on conditioned place preferences associated with ejaculation and intromissions Horm. Behav. 55 1 2009 93 97
230. A.M. Traish Androgens play a pivotal role in maintaining penile tissue architecture and erection: a review J. Androl. 30 4 2009 363 369
231. A.M. Traish, I. Goldstein, and N.N. Kim Testosterone and erectile function: from basic research to a new clinical paradigm for managing men with androgen insufficiency and erectile dysfunction Eur. Urol. 52 1 2007 54 70 (Pubitemid 46803026)
232. M.I. Trenell, N.S. Marshall, and N.L. Rogers Sleep and metabolic control: waking to a problem? Clin. Exp. Pharmacol. Physiol. 34 1-2 2007 1 9 (Pubitemid 46069578)
233. S. Tufik, M.L. Andersen, L.R. Bittencourt, and M.T. Mello Paradoxical sleep deprivation: neurochemical, hormonal and behavioral alterations. Evidence from 30 years of research An Acad. Bras. Cienc. 81 3 2009 521 538
234. S. Tufik, C.J. Lindsey, and E.A. Carlini Does REM sleep deprivation induce a supersensitivity of dopaminergic receptors in the rat brain? Pharmacology 16 2 1978 98 105 (Pubitemid 8230482)
235. S. Tufik, R. Santos-Silva, J.A. Taddei, and L.R. Bittencourt Obstructive sleep apnea syndrome in the Sao Paulo Epidemiologic Sleep Study Sleep Med. 11 5 2010 441 446
236. A. Tuiten, J. Van Honk, H. Koppeschaar, C. Bernaards, J. Thijssen, and R. Verbaten Time course of effects of testosterone administration on sexual arousal in women Arch. Gen. Psychiatry 57 2 2000 149 153 discussion 155-146. (Pubitemid 30075265)
237. F.W. Turek Gender (sex) and sleep: shh... not in front of the children Sleep 29 1 2006 21 22 (Pubitemid 44019026)
238. S.M. van Anders, L.D. Hamilton, and N.V. Watson Multiple partners are associated with higher testosterone in North American men and women Horm. Behav. 51 3 2007 454 459 (Pubitemid 46365694)
239. E. Van Cauter Endocrine Physiology 4 ed. 2005
240. G. Vazquez-Palacios, H. Bonilla-Jaime, S. Retana-Marquez, and J. Velazquez-Moctezuma Copulatory activity increases slow-wave sleep in the male rat J. Sleep Res. 11 3 2002 237 245 (Pubitemid 35014009)
241. J. Velazquez-Moctezuma, E. Monroy, and M.L. Cruz Facilitation of the effect testosterone on male sexual behavior in rats deprived of REM sleep Behav. Neural Biol. 51 1 1989 46 53 (Pubitemid 19031964)
242. J. Velazquez-Moctezuma, E. Monroy, C. Beyer, and E. Canchola Effects of REM deprivation on the lordosis response induced by gonadal steroids in ovariectomized rats Physiol. Behav. 32 1 1984 91 94 (Pubitemid 14179687)
243. J. Velazquez-Moctezuma, E.D. Salazar, and S. Retana-Marquez Effects of short- and long-term REM sleep deprivation on sexual behavior in male rats Physiol. Behav. 59 2 1996 277 281 (Pubitemid 26075108)
244. J.D. Veldhuis Contemporary insights into the regulation of luteinizing hormone secretion in man Horm. Res. 28 2-4 1987 126 138
245. J.D. Veldhuis, A. Iranmanesh, M. Godschalk, and T. Mulligan Older men manifest multifold synchrony disruption of reproductive neurohormone outflow J. Clin. Endocrinol. Metab. 85 4 2000 1477 1486 (Pubitemid 32289489)
246. D.P. Venancio, S. Tufik, S.A. Garbuio, A.C. da Nobrega, and M.T. de Mello Effects of anabolic androgenic steroids on sleep patterns of individuals practicing resistance exercise Eur. J. Appl. Physiol. 102 5 2008 555 560
247. S. Verma, G.S. Chhina, V.M. Kumar, and B. Singh Effect of rapid eye movement sleep deprivation on sexual behaviour of male rats Indian J. Exp. Biol. 27 10 1989 892 894
248. A.H. Vidal, and B.V. Vaughn Testosterone levels in sleep related breathing disorders Sleep 24 2001 A297 A298
249. P. Vimont-Vicary, D. Jouvet-Mounier, and F. Delorme EEG and behavioral effects of deprivation of paradoxical sleep in cats Electroencephalogr. Clin. Neurophysiol. 20 5 1966 439 449
250. B.L. Wajchenberg Subcutaneous and visceral adipose tissue: their relation to the metabolic syndrome Endocr. Rev. 21 6 2000 697 738 (Pubitemid 32113289)
251. S.E. Waxenberg, M.G. Drellich, and A.M. Sutherland The role of hormones in human behavior. I. Changes in female sexuality after adrenalectomy J. Clin. Endocrinol. Metab. 19 2 1959 193 202
252. D.P. White, B.K. Schneider, R.J. Santen, M. McDermott, C.K. Pickett, and C.W. Zwillich Influence of testosterone on ventilation and chemosensitivity in male subjects J. Appl. Physiol. 59 5 1985 1452 1457 (Pubitemid 16197409)
253. G.W. Williams, J. Goldman, M.Y. McGinnis, B. Possidente, and A.R. Lumia Effects of ovarian hormones on sexual receptivity, proceptivity, and motivation in olfactory bulbectomized female rats Physiol. Behav. 50 4 1991 751 755
254. N.F. Woods, K. Smith-Dijulio, D.B. Percival, E.Y. Tao, H.J. Taylor, and E.S. Mitchell Symptoms during the menopausal transition and early postmenopause and their relation to endocrine levels over time: observations from the Seattle Midlife Women's Health Study J. Womens Health (Larchmt) 16 5 2007 667 677 (Pubitemid 47093910)
255. N.F. Woods, and E.S. Mitchell Sleep symptoms during the menopausal transition and early postmenopause: observations from the Seattle Midlife Women's Health Study Sleep 33 4 2010 539 549
256. D. Wu, and A.C. Gore Sexual experience changes sex hormones but not hypothalamic steroid hormone receptor expression in young and middle-aged male rats Horm. Behav. 56 3 2009 299 308
257. T. Young, D. Rabago, A. Zgierska, D. Austin, and F. Laurel Objective and subjective sleep quality in premenopausal, perimenopausal, and postmenopausal women in the Wisconsin Sleep Cohort Study Sleep 26 6 2003 667 672 (Pubitemid 39619775)
258. T. Young, J. Skatrud, and P.E. Peppard Risk factors for obstructive sleep apnea in adults JAMA 291 16 2004 2013 2016 (Pubitemid 38544284)
259. J.E. Zadina, J.L. Dunlap, and A.A. Gerall Modifications induced by neonatal steroids in reproductive organs and behavior of male rats J. Comp. Physiol. Psychol. 93 2 1979 314 322 (Pubitemid 9152383)
260. V. Zarcone, E. Zukowsky, G. Gulevich, W. Dement, and E. Hoddes Rorschach responses subsequent to REM deprivation in schizophrenic and nonschizophrenic patients J. Clin. Psychol. 30 3 1974 248 250
261. F.A. Zarrouf, S. Artz, J. Griffith, C. Sirbu, and M. Kommor Testosterone and depression: systematic review and meta-analysis J. Psychiatr. Pract. 15 4 2009 289 305
262. A.J. Zeleznik, and C.R. Pohl Control of Follicular Development, Corpus Luteum Function, the Maternal Recognition of Pregnancy, and the Neuroendocrine Regulation of the Menstrual Cycle in Higher Primates 3 ed. 2006
263. B. Zhang, and Y.K. Wing Sex differences in insomnia: a meta-analysis Sleep 29 1 2006 85 93 (Pubitemid 44019033)
264. S.Q. Zhang, M. Kimura, and S. Inoue Sleep patterns in cyclic and pseudopregnant rats Neurosci. Lett. 193 2 1995 125 128
265. X.S. Zhou, J.A. Rowley, F. Demirovic, M.P. Diamond, and M.S. Badr Effect of testosterone on the apneic threshold in women during NREM sleep J. Appl. Physiol. 94 1 2003 101 107 (Pubitemid 36014301)
266. V.N. Zhuravlev, M.A. Frank, and A.I. Gomzhin Sexual functions of men with obstructive sleep apnoea syndrome and hypogonadism may improve upon testosterone administration: a pilot study Andrologia 41 3 2009 193 195