Hormonal changes in menopause and implications on sexual health

Journal of Sexual Medicine

Volumn 4, Issue SUPPL. 3, 2007, Pages 220-226

  Schwenkhagen, Anneliese ^a,b  

^a Gynaekologicum Hamburg   (Germany)

^b NONE   (Germany)

Author keywords

Androgen; Deficiency; Estrogen; Menopause; Testosterone

Indexed keywords

ANDROGEN; ANTIANDROGEN; CONJUGATED ESTROGEN; ESTRADIOL BENZOATE; ESTRADIOL DERIVATIVE; ESTRADIOL DIENANTATE; ESTRADIOL VALERATE; ESTROGEN; GESTAGEN; GLUCOCORTICOID; HORMONE PRECURSOR; METHYLTESTOSTERONE; ORAL CONTRACEPTIVE AGENT; PLACEBO; PROGESTERONE; TESTOSTERONE; TESTOSTERONE ENANTATE; TESTOSTERONE UNDECANOATE; UNCLASSIFIED DRUG;

ADRENAL GLAND; ANDROGEN BLOOD LEVEL; ANDROGEN DEFICIENCY; BLEEDING DISORDER; CLIMACTERIUM; CLINICAL TRIAL; COMBINATION CHEMOTHERAPY; DRUG FORMULATION; DRUG HALF LIFE; ENDOCRINE FUNCTION; ESTROGEN BLOOD LEVEL; ESTROGEN DEFICIENCY; ESTROGEN SYNTHESIS; FEMALE SEXUAL DYSFUNCTION; HORMONAL REGULATION; HORMONE SUBSTITUTION; HOT FLUSH; HUMAN; LUBRICATION; MENOPAUSE; META ANALYSIS; MONOTHERAPY; MOOD CHANGE; MOTIVATION; OVARY; OVARY FOLLICLE; POSTMENOPAUSE; PRIORITY JOURNAL; PROGESTERONE SYNTHESIS; REVIEW; SEXUAL AROUSAL; SEXUAL HEALTH; SIDE EFFECT; SLEEP DISORDER; SYSTEMATIC REVIEW; TESTOSTERONE BLOOD LEVEL; TESTOSTERONE SYNTHESIS; UROGENITAL TRACT DISEASE; VAGINA;

EID: 33847692262     PISSN: 17436095     EISSN: 17436109     Source Type: Journal    
DOI: 10.1111/j.1743-6109.2007.00448.x     Document Type: Article

References (23)

1. Dennerstein L, Hayes RD. Confronting the challenges: Epidemiological study of female sexual dysfunction and the menopause. J Sex Med 2005; 2 (suppl 3): 118-32.
2. Graziottin A, Leiblum SR. Biological and psychosocial pathophysiology of female sexual dysfunction during the menopausal transition. J Sex Med 2005; 2 (suppl 3): 133-45.
3. Jeong GW, Park K, Youn G, Kang HK, Kim HJ, Seo JJ, Ryu SB. Assessment of cerebrocortical regions associated with sexual arousal in premenopausal and menopausal women by using BOLD-based functional MRI. J Sex Med 2005; 2: 645-51.
4. Dennerstein L, Lehert P, Burger H. The relative effects of hormones and relationship factors on sexual function of women through the natural menopausal transition. Fertil Steril 2005; 84: 174-80.
5. Davison SL, Bell R, Donath S, Montalto JG, Davis SR. Androgen levels in adult females: Changes with age, menopause, and oophorectomy. J Clin Endocrinol Metab 2005; 90: 3847-53.
6. Buster JE, Kingsberg SA, Aguirre O, Brown C, Breaux JG, Buch A, Rodenberg CA, Wekselman K, Casson P. Testosterone patch for low sexual desire in surgically menopausal women: A randomized trial. Obstet Gynecol 2005; 105 (5 Part 1): 944-52.
7. Lobo RA. Treatment of the postmenopausal women: Basic and clinical aspects. 2nd edition. Philadelphia, PA: Lippincott Williams & Wilkins; 1999.
8. Simon JA. Estrogen replacement therapy: Effects on the endogenous androgen milieu. Fertil Steril 2002; 77 (suppl 4): S77-82.
9. Laughlin GA, Barrett-Connor E, Kritz-Silverstein D, von Muhlen D. Hysterectomy, oophorectomy, and endogenous sex hormone levels in older women: The Rancho Bernardo Study. J Clin Endocrinol Metab 2000; 85: 645-51.
10. Dennerstein L, Dudley E, Burger H. Are changes in sexual functioning during midlife due to aging or menopause? Fertil Steril 2001; 76: 456-60.
11. Bachmann GA, Leiblum SR. The impact of hormones on menopausal sexuality: A literature review. Menopause 2004; 11: 120-30.
12. Davis SR. When to suspect androgen deficiency other than at menopause. Fertil Steril 2002; 77 (suppl 4): S68-71.
13. Bachmann G, Bancroft J, Braunstein G, Burger H, Davis S, Dennerstein L, Goldstein I, Guay A, Leiblum S, Lobo R, Notelovitz M, Rosen R, Sarrel P, Sherwin B, Simon J, Simpson E, Shifren J, Spark R, Traish A. Female androgen insufficiency: The Princeton consensus statement on definition, classification, and assessment. Fertil Steril 2002; 77: 660-5.
14. Braunstein GD. Androgen insufficiency in women: Summary of critical issues. Fertil Steril 2002; 77 (suppl 4): S94-9.
15. Dennerstein L, Koochaki P, Barton I, Graziottin A. Hypoactive sexual desire disorder in menopausal women: A survey of Western European women. J Sex Med 2006; 3: 212-22.
16. Leiblum S, Symonds T, Moore J, Soni P, Steinberg S, Sisson M. A methodology study to develop and validate a screener for hypoactive sexual desire disorder in postmenopausal women. J Sex Med 2006; 3: 455-64.
17. Segraves R, Woodard T. Female hypoactive sexual desire disorder: History and current status. J Sex Med 2006; 3: 408-18.
18. North American Menopause Society. The role of testosterone therapy in postmenopausal women: Position statement of North American Menopause Society. Menopause 2005; 12: 497-511.
19. Somboonporn W, Davis S, Seif MW, Bell R. Testosterone for peri- and postmenopausal women. Cochrane Database Syst Rev 2005; (4):CD004509.
20. Simon J, Braunstein G, Nachtigall L, Utian W, Katz M, Miller S, Waldbaum A, Bouchard C, Derzko C, Buch A, Rodenberg C, Lucas J, Davis S. Testosterone patch increases sexual activity and desire in surgically menopausal women with hypoactive sexual desire disorder. J Clin Endocrinol Metab 2005; 90: 5226-33.
21. Shifren JL, Davis SR, Moreau M, Waldbaum A, Bouchard C, Derogatis L, Derzko C, Bearnson P, Kakos N, O'Neill S, Levine S, Wekselman K, Buch A, Rodenberg C, Kroll R. Testosterone patch for the treatment of hypoactive sexual desire disorder in naturally menopausal women: Results from the INTIMATE NM1 Study. Menopause 2006; 13: 770-9.
22. Goldstein I, Alexander JL. Practical aspects in the management of vaginal atrophy and sexual dysfunction in perimenopausal and postmenopausal women. J Sex Med 2005; 2 (suppl 3): 154-65.
23. Nijland E, Davis S, Laan E, Schultz WW. Female sexual satisfaction and pharmaceutical intervention: A critical review of the drug intervention studies in female sexual dysfunction. J Sex Med 2006; 3: 763-77.