-
1
-
-
0026786471
-
Regulation of protein serine-threonine phosphatase type-2A by tyrosine phosphorylation
-
J. Chen, B.L. Martin, and D.L. Brautigan Regulation of protein serine-threonine phosphatase type-2A by tyrosine phosphorylation Science 257 1992 1261 1264
-
(1992)
Science
, vol.257
, pp. 1261-1264
-
-
Chen, J.1
Martin, B.L.2
Brautigan, D.L.3
-
2
-
-
71849104427
-
Tickled PINK1: Mitochondrial homeostasis and autophagy in recessive Parkinsonism
-
C.T. Chu Tickled PINK1: mitochondrial homeostasis and autophagy in recessive Parkinsonism Biochim. Biophys. Acta 1802 2010 20 28
-
(2010)
Biochim. Biophys. Acta
, vol.1802
, pp. 20-28
-
-
Chu, C.T.1
-
3
-
-
77953890085
-
Parkinson's disease: Insights from pathways
-
M.R. Cookson, and O. Bandmann Parkinson's disease: insights from pathways Hum. Mol. Genet. 19 2010 R21 R27
-
(2010)
Hum. Mol. Genet.
, vol.19
-
-
Cookson, M.R.1
Bandmann, O.2
-
4
-
-
79956278232
-
Silencing of PINK1 induces mitophagy via mitochondrial permeability transition in dopaminergic MN9D cells
-
T. Cui, C. Fan, L. Gu, H. Gao, Q. Liu, T. Zhang, Z. Qi, C. Zhao, H. Zhao, Q. Cai, and H. Yang Silencing of PINK1 induces mitophagy via mitochondrial permeability transition in dopaminergic MN9D cells Brain Res. 1394 2011 1 13
-
(2011)
Brain Res.
, vol.1394
, pp. 1-13
-
-
Cui, T.1
Fan, C.2
Gu, L.3
Gao, H.4
Liu, Q.5
Zhang, T.6
Qi, Z.7
Zhao, C.8
Zhao, H.9
Cai, Q.10
Yang, H.11
-
5
-
-
67649399288
-
Loss of PINK1 function promotes mitophagy through effects on oxidative stress and mitochondrial fission
-
R.K. Dagda, S.J. Cherra III, S.M. Kulich, A. Tandon, D. Park, and C.T. Chu Loss of PINK1 function promotes mitophagy through effects on oxidative stress and mitochondrial fission J. Biol. Chem. 284 2009 13843 13855
-
(2009)
J. Biol. Chem.
, vol.284
, pp. 13843-13855
-
-
Dagda, R.K.1
Cherra Iii, S.J.2
Kulich, S.M.3
Tandon, A.4
Park, D.5
Chu, C.T.6
-
6
-
-
27144469287
-
Small interfering RNA targeting the PINK1 induces apoptosis in dopaminergic cells SH-SY5Y
-
DOI 10.1016/j.bbrc.2005.09.178, PII S0006291X05022205
-
H. Deng, J. Jankovic, Y. Guo, W. Xie, and W. Le Small interfering RNA targeting the PINK1 induces apoptosis in dopaminergic cells SH-SY5Y Biochem. Biophys. Res. Commun. 337 2005 1133 1138 (Pubitemid 41505244)
-
(2005)
Biochemical and Biophysical Research Communications
, vol.337
, Issue.4
, pp. 1133-1138
-
-
Deng, H.1
Jankovic, J.2
Guo, Y.3
Xie, W.4
Le, W.5
-
7
-
-
69149089854
-
Inclusion formation and neuronal cell death through neuron-to-neuron transmission of alpha-synuclein
-
P. Desplats, H.J. Lee, E.J. Bae, C. Patrick, E. Rockenstein, L. Crews, B. Spencer, E. Masliah, and S.J. Lee Inclusion formation and neuronal cell death through neuron-to-neuron transmission of alpha-synuclein Proc. Natl. Acad. Sci. USA 106 2009 13010 13015
-
(2009)
Proc. Natl. Acad. Sci. USA
, vol.106
, pp. 13010-13015
-
-
Desplats, P.1
Lee, H.J.2
Bae, E.J.3
Patrick, C.4
Rockenstein, E.5
Crews, L.6
Spencer, B.7
Masliah, E.8
Lee, S.J.9
-
8
-
-
62449287501
-
The paradox of autophagy and its implication in cancer etiology and therapy
-
A. Eisenberg-Lerner, and A. Kimchi The paradox of autophagy and its implication in cancer etiology and therapy Apoptosis 14 2009 376 391
-
(2009)
Apoptosis
, vol.14
, pp. 376-391
-
-
Eisenberg-Lerner, A.1
Kimchi, A.2
-
9
-
-
77956672926
-
Loss of Hsp110 leads to age-dependent tau hyperphosphorylation and early accumulation of insoluble amyloid beta
-
B. Eroglu, D. Moskophidis, and N.F. Mivechi Loss of Hsp110 leads to age-dependent tau hyperphosphorylation and early accumulation of insoluble amyloid beta Mol. Cell. Biol. 30 2010 4626 4643
-
(2010)
Mol. Cell. Biol.
, vol.30
, pp. 4626-4643
-
-
Eroglu, B.1
Moskophidis, D.2
Mivechi, N.F.3
-
10
-
-
77953050555
-
Protein phosphatase 2A (PP2A) is increased in old murine B cells and mediates p38 MAPK/tristetraprolin dephosphorylation and E47 mRNA instability
-
D. Frasca, M. Romero, A.M. Landin, A. Diaz, R.L. Riley, and B.B. Blomberg Protein phosphatase 2A (PP2A) is increased in old murine B cells and mediates p38 MAPK/tristetraprolin dephosphorylation and E47 mRNA instability Mech. Ageing Dev. 131 2010 306 314
-
(2010)
Mech. Ageing Dev.
, vol.131
, pp. 306-314
-
-
Frasca, D.1
Romero, M.2
Landin, A.M.3
Diaz, A.4
Riley, R.L.5
Blomberg, B.B.6
-
11
-
-
33745087689
-
PINK1 protein in normal human brain and Parkinson's disease
-
DOI 10.1093/brain/awl114
-
S. Gandhi, M.M. Muqit, L. Stanyer, D.G. Healy, P.M. bou-Sleiman, I. Hargreaves, S. Heales, M. Ganguly, L. Parsons, A.J. Lees, D.S. Latchman, J.L. Holton, N.W. Wood, and T. Revesz PINK1 protein in normal human brain and Parkinson's disease Brain 129 2006 1720 1731 (Pubitemid 43999406)
-
(2006)
Brain
, vol.129
, Issue.7
, pp. 1720-1731
-
-
Gandhi, S.1
Muqit, M.M.K.2
Stanyer, L.3
Healy, D.G.4
Abou-Sleiman, P.M.5
Hargreaves, I.6
Heales, S.7
Ganguly, M.8
Parsons, L.9
Lees, A.J.10
Latchman, D.S.11
Holton, J.L.12
Wood, N.W.13
Revesz, T.14
-
12
-
-
49649097747
-
Loss of PINK1 causes mitochondrial functional defects and increased sensitivity to oxidative stress
-
C.A. Gautier, T. Kitada, and J. Shen Loss of PINK1 causes mitochondrial functional defects and increased sensitivity to oxidative stress Proc. Natl. Acad. Sci. USA 105 2008 11364 11369
-
(2008)
Proc. Natl. Acad. Sci. USA
, vol.105
, pp. 11364-11369
-
-
Gautier, C.A.1
Kitada, T.2
Shen, J.3
-
13
-
-
62749113469
-
Silencing of PINK1 expression affects mitochondrial DNA and oxidative phosphorylation in dopaminergic cells
-
M.E. Gegg, J.M. Cooper, A.H. Schapira, and J.W. Taanman Silencing of PINK1 expression affects mitochondrial DNA and oxidative phosphorylation in dopaminergic cells PLoS One 4 2009 e4756
-
(2009)
PLoS One
, vol.4
, pp. 4756
-
-
Gegg, M.E.1
Cooper, J.M.2
Schapira, A.H.3
Taanman, J.W.4
-
14
-
-
75949130828
-
PINK1/Parkin-mediated mitophagy is dependent on VDAC1 and p62/SQSTM1
-
S. Geisler, K.M. Holmstrom, D. Skujat, F.C. Fiesel, O.C. Rothfuss, P.J. Kahle, and W. Springer PINK1/Parkin-mediated mitophagy is dependent on VDAC1 and p62/SQSTM1 Nat. Cell Biol. 12 2010 119 131
-
(2010)
Nat. Cell Biol.
, vol.12
, pp. 119-131
-
-
Geisler, S.1
Holmstrom, K.M.2
Skujat, D.3
Fiesel, F.C.4
Rothfuss, O.C.5
Kahle, P.J.6
Springer, W.7
-
15
-
-
77950994646
-
Autophagy: Cellular and molecular mechanisms
-
D. Glick, S. Barth, and K.F. Macleod Autophagy: cellular and molecular mechanisms J. Pathol. 221 2010 3 12
-
(2010)
J. Pathol.
, vol.221
, pp. 3-12
-
-
Glick, D.1
Barth, S.2
MacLeod, K.F.3
-
16
-
-
62449091002
-
New insights on the role of apoptosis and autophagy in HIV pathogenesis
-
M.L. Gougeon, and M. Piacentini New insights on the role of apoptosis and autophagy in HIV pathogenesis Apoptosis 14 2009 501 508
-
(2009)
Apoptosis
, vol.14
, pp. 501-508
-
-
Gougeon, M.L.1
Piacentini, M.2
-
17
-
-
39449098267
-
Cytoplasmic Pink1 activity protects neurons from dopaminergic neurotoxin MPTP
-
DOI 10.1073/pnas.0705363105
-
M.E. Haque, K.J. Thomas, C. D'Souza, S. Callaghan, T. Kitada, R.S. Slack, P. Fraser, M.R. Cookson, A. Tandon, and D.S. Park Cytoplasmic Pink1 activity protects neurons from dopaminergic neurotoxin MPTP Proc. Natl. Acad. Sci. USA 105 2008 1716 1721 (Pubitemid 351346580)
-
(2008)
Proceedings of the National Academy of Sciences of the United States of America
, vol.105
, Issue.5
, pp. 1716-1721
-
-
Haque, M.E.1
Thomas, K.J.2
D'Souza, C.3
Callaghan, S.4
Kitada, T.5
Slack, R.S.6
Fraser, P.7
Cookson, M.R.8
Tandon, A.9
Park, D.S.10
-
18
-
-
38949108670
-
Guidelines for the use and interpretation of assays for monitoring autophagy in higher eukaryotes
-
D.J. Klionsky Guidelines for the use and interpretation of assays for monitoring autophagy in higher eukaryotes Autophagy 4 2008 151 175 (Pubitemid 351231180)
-
(2008)
Autophagy
, vol.4
, Issue.2
, pp. 151-175
-
-
Klionsky, D.J.1
Abeliovich, H.2
Agostinis, P.3
Agrawal, D.K.4
Aliev, G.5
Askew, D.S.6
Baba, M.7
Baehrecke, E.H.8
Bahr, B.A.9
Ballabio, A.10
Bamber, B.A.11
Bassham, D.C.12
Bergamini, E.13
Bi, X.14
Biard-Piechaczyk, M.15
Blum, J.S.16
Bredesen, D.E.17
Brodsky, J.L.18
Brumell, J.H.19
Brunk, U.T.20
Bursch, W.21
Camougrand, N.22
Cebollero, E.23
Cecconi, F.24
Chen, Y.25
Chin, L.-S.26
Choi, A.27
Chu, C.T.28
Chung, J.29
Clarke, P.G.H.30
Clark, R.S.B.31
Clarke, S.G.32
Clave, C.33
Cleveland, J.L.34
Codogno, P.35
Colombo, M.I.36
Cotomontes, A.37
Cregg, J.M.38
Cuervo, A.M.39
Debnath, J.40
Demarchi, F.41
Dennis, P.B.42
Dennis, P.A.43
Deretic, V.44
Devenish, R.J.45
Di Sano, F.46
Dice, J.F.47
DiFiglia, M.48
Dinesh-Kumar, S.49
Distelhorst, C.W.50
Djavaheri-Mergny, M.51
Dorsey, F.C.52
Droge, W.53
Dron, M.54
Dunn Jr., W.A.55
Duszenko, M.56
more..
-
19
-
-
34247866596
-
Direct binding of PP2A to Sprouty2 and phosphorylation changes are a prerequisite for ERK inhibition downstream of fibroblast growth factor receptor stimulation
-
DOI 10.1074/jbc.M607563200
-
D.H. Lao, P. Yusoff, S. Chandramouli, R.J. Philp, C.W. Fong, R.A. Jackson, T.Y. Saw, C.Y. Yu, and G.R. Guy Direct binding of PP2A to Sprouty2 and phosphorylation changes are a prerequisite for ERK inhibition downstream of fibroblast growth factor receptor stimulation J. Biol. Chem. 282 2007 9117 9126 (Pubitemid 47093531)
-
(2007)
Journal of Biological Chemistry
, vol.282
, Issue.12
, pp. 9117-9126
-
-
Lao, D.-H.1
Yusoff, P.2
Chandramouli, S.3
Philp, R.J.4
Chee, W.F.5
Jackson, R.A.6
Tzuen, Y.S.7
Chye, Y.Y.8
Guy, G.R.9
-
20
-
-
82755163086
-
I(2)(PP2A) regulates p53 and Akt correlatively and leads the neurons to abort apoptosis
-
doi:10.1016/j.neurobiolaging.2010.01.016
-
Liu, G.P., Wei, W., Zhou, X., Zhang, Y., Shi, H.H., Yin, J., Yao, X., Q., Peng, C.X., Hu, J., Wang, Q., Li, H.L., Wang, J.Z., 2010. I(2)(PP2A) regulates p53 and Akt correlatively and leads the neurons to abort apoptosis. Neurobiol. Aging. doi:10.1016/j.neurobiolaging.2010.01.016.
-
(2010)
Neurobiol. Aging.
-
-
Liu, G.P.1
Wei, W.2
Zhou, X.3
Zhang, Y.4
Shi, H.H.5
Yin, J.6
Yao, X.Q.7
Peng, C.X.8
Hu, J.9
Wang, Q.10
Li, H.L.11
Wang, J.Z.12
-
21
-
-
67650860453
-
Inhibition of serine/threonine phosphatase PP2A enhances cancer chemotherapy by blocking DNA damage induced defense mechanisms
-
J. Lu, J.S. Kovach, F. Johnson, J. Chiang, R. Hodes, R. Lonser, and Z. Zhuang Inhibition of serine/threonine phosphatase PP2A enhances cancer chemotherapy by blocking DNA damage induced defense mechanisms Proc. Natl. Acad. Sci. USA 106 2009 11697 11702
-
(2009)
Proc. Natl. Acad. Sci. USA
, vol.106
, pp. 11697-11702
-
-
Lu, J.1
Kovach, J.S.2
Johnson, F.3
Chiang, J.4
Hodes, R.5
Lonser, R.6
Zhuang, Z.7
-
22
-
-
69249096578
-
Loss of parkin or PINK1 function increases Drp1-dependent mitochondrial fragmentation
-
A.K. Lutz, N. Exner, M.E. Fett, J.S. Schlehe, K. Kloos, K. Lammermann, B. Brunner, A. Kurz-Drexler, F. Vogel, A.S. Reichert, L. Bouman, D. Vogt-Weisenhorn, W. Wurst, J. Tatzelt, C. Haass, and K.F. Winklhofer Loss of parkin or PINK1 function increases Drp1-dependent mitochondrial fragmentation J. Biol. Chem. 284 2009 22938 22951
-
(2009)
J. Biol. Chem.
, vol.284
, pp. 22938-22951
-
-
Lutz, A.K.1
Exner, N.2
Fett, M.E.3
Schlehe, J.S.4
Kloos, K.5
Lammermann, K.6
Brunner, B.7
Kurz-Drexler, A.8
Vogel, F.9
Reichert, A.S.10
Bouman, L.11
Vogt-Weisenhorn, D.12
Wurst, W.13
Tatzelt, J.14
Haass, C.15
Winklhofer, K.F.16
-
23
-
-
77951199668
-
Decreased expression of Drp1 and Fis1 mediates mitochondrial elongation in senescent cells and enhances resistance to oxidative stress through PINK1
-
S. Mai, M. Klinkenberg, G. Auburger, J. Bereiter-Hahn, and M. Jendrach Decreased expression of Drp1 and Fis1 mediates mitochondrial elongation in senescent cells and enhances resistance to oxidative stress through PINK1 J. Cell Sci. 123 2010 917 926
-
(2010)
J. Cell Sci.
, vol.123
, pp. 917-926
-
-
Mai, S.1
Klinkenberg, M.2
Auburger, G.3
Bereiter-Hahn, J.4
Jendrach, M.5
-
24
-
-
34250894388
-
L
-
M.C. Maiuri, A. Criollo, E. Tasdemir, J.M. Vicencio, N. Tajeddine, J.A. Hickman, O. Geneste, and G. Kroemer BH3-only proteins and BH3 mimetics induce autophagy by competitively disrupting the interaction between Beclin 1 and Bcl-2/Bcl-X(L) Autophagy 3 2007 374 376 (Pubitemid 46986348)
-
(2007)
Autophagy
, vol.3
, Issue.4
, pp. 374-376
-
-
Maiuri, M.C.1
Criollo, A.2
Tasdemir, E.3
Vicencio, J.M.4
Tajeddine, N.5
Hickman, J.A.6
Geneste, O.7
Kroemer, G.8
-
25
-
-
34548188741
-
Self-eating and self-killing: Crosstalk between autophagy and apoptosis
-
DOI 10.1038/nrm2239, PII NRM2239
-
M.C. Maiuri, E. Zalckvar, A. Kimchi, and G. Kroemer Self-eating and self-killing: crosstalk between autophagy and apoptosis Nat. Rev. Mol. Cell Biol. 8 2007 741 752 (Pubitemid 47312826)
-
(2007)
Nature Reviews Molecular Cell Biology
, vol.8
, Issue.9
, pp. 741-752
-
-
Maiuri, M.C.1
Zalckvar, E.2
Kimchi, A.3
Kroemer, G.4
-
26
-
-
41149114560
-
Biochemical aspects of the neuroprotective mechanism of PTEN-induced kinase-1 (PINK1)
-
DOI 10.1111/j.1471-4159.2008.05249.x
-
R.D. Mills, C.H. Sim, S.S. Mok, T.D. Mulhern, J.G. Culvenor, and H.C. Cheng Biochemical aspects of the neuroprotective mechanism of PTEN-induced kinase-1 (PINK1) J. Neurochem. 105 2008 18 33 (Pubitemid 351441646)
-
(2008)
Journal of Neurochemistry
, vol.105
, Issue.1
, pp. 18-33
-
-
Mills, R.D.1
Sim, C.H.2
Mok, S.S.3
Mulhern, T.D.4
Culvenor, J.G.5
Cheng, H.-C.6
-
27
-
-
77953666757
-
Parkinson's disease mutations in PINK1 result in decreased Complex i activity and deficient synaptic function
-
V.A. Morais, P. Verstreken, A. Roethig, J. Smet, A. Snellinx, M. Vanbrabant, D. Haddad, C. Frezza, W. Mandemakers, D. Vogt-Weisenhorn, C.R. Van, W. Wurst, L. Scorrano, and B. De Strooper Parkinson's disease mutations in PINK1 result in decreased Complex I activity and deficient synaptic function EMBO Mol. Med. 1 2009 99 111
-
(2009)
EMBO Mol. Med.
, vol.1
, pp. 99-111
-
-
Morais, V.A.1
Verstreken, P.2
Roethig, A.3
Smet, J.4
Snellinx, A.5
Vanbrabant, M.6
Haddad, D.7
Frezza, C.8
Mandemakers, W.9
Vogt-Weisenhorn, D.10
Van, C.R.11
Wurst, W.12
Scorrano, L.13
De Strooper, B.14
-
28
-
-
58149314211
-
Parkin is recruited selectively to impaired mitochondria and promotes their autophagy
-
D. Narendra, A. Tanaka, D.F. Suen, and R.J. Youle Parkin is recruited selectively to impaired mitochondria and promotes their autophagy J. Cell Biol. 183 2008 795 803
-
(2008)
J. Cell Biol.
, vol.183
, pp. 795-803
-
-
Narendra, D.1
Tanaka, A.2
Suen, D.F.3
Youle, R.J.4
-
29
-
-
75749156257
-
PINK1 is selectively stabilized on impaired mitochondria to activate Parkin
-
D.P. Narendra, S.M. Jin, A. Tanaka, D.F. Suen, C.A. Gautier, J. Shen, M.R. Cookson, and R.J. Youle PINK1 is selectively stabilized on impaired mitochondria to activate Parkin PLoS Biol. 8 2010 e1000298
-
(2010)
PLoS Biol.
, vol.8
, pp. 1000298
-
-
Narendra, D.P.1
Jin, S.M.2
Tanaka, A.3
Suen, D.F.4
Gautier, C.A.5
Shen, J.6
Cookson, M.R.7
Youle, R.J.8
-
30
-
-
77954104112
-
Genetic etiology of Parkinson disease associated with mutations in the SNCA, PARK2, PINK1, PARK7, and LRRK2 genes: A mutation update
-
K. Nuytemans, J. Theuns, M. Cruts, and C. Van Broeckhoven Genetic etiology of Parkinson disease associated with mutations in the SNCA, PARK2, PINK1, PARK7, and LRRK2 genes: a mutation update Hum. Mutat. 31 2010 763 780
-
(2010)
Hum. Mutat.
, vol.31
, pp. 763-780
-
-
Nuytemans, K.1
Theuns, J.2
Cruts, M.3
Van Broeckhoven, C.4
-
31
-
-
39449088321
-
The PINK1/Parkin pathway regulates mitochondrial morphology
-
DOI 10.1073/pnas.0709336105
-
A.C. Poole, R.E. Thomas, L.A. Andrews, H.M. McBride, A.J. Whitworth, and L.J. Pallanck The PINK1/Parkin pathway regulates mitochondrial morphology Proc. Natl. Acad. Sci. USA 105 2008 1638 1643 (Pubitemid 351346567)
-
(2008)
Proceedings of the National Academy of Sciences of the United States of America
, vol.105
, Issue.5
, pp. 1638-1643
-
-
Poole, A.C.1
Thomas, R.E.2
Andrews, L.A.3
McBride, H.M.4
Whitworth, A.J.5
Pallanck, L.J.6
-
32
-
-
34447640753
-
Increased membrane/nuclear translocation and phosphorylation of p90 KD ribosomal S6 kinase in the brain of hypoxic preconditioned mice
-
DOI 10.1007/s11064-007-9331-z
-
Z. Qi, X. Bu, P. Huang, N. Zhang, S. Han, L. Fang, and J. Li Increased membrane/nuclear translocation and phosphorylation of p90 KD ribosomal S6 kinase in the brain of hypoxic preconditioned mice Neurochem. Res. 32 2007 1450 1459 (Pubitemid 47094406)
-
(2007)
Neurochemical Research
, vol.32
, Issue.9
, pp. 1450-1459
-
-
Qi, Z.1
Bu, X.2
Huang, P.3
Zhang, N.4
Han, S.5
Fang, L.6
Li, J.7
-
33
-
-
69949175897
-
Review: Autophagy in neurodegeneration: Firefighter and/or incendiarist?
-
A. Rami Review: autophagy in neurodegeneration: firefighter and/or incendiarist? Neuropathol. Appl. Neurobiol. 35 2009 449 461
-
(2009)
Neuropathol. Appl. Neurobiol.
, vol.35
, pp. 449-461
-
-
Rami, A.1
-
34
-
-
72449200109
-
Peptidyl-prolyl isomerase 1 regulates protein phosphatase 2A-mediated topographic phosphorylation of neurofilament proteins
-
P. Rudrabhatla, W. Albers, and H.C. Pant Peptidyl-prolyl isomerase 1 regulates protein phosphatase 2A-mediated topographic phosphorylation of neurofilament proteins J. Neurosci. 29 2009 14869 14880
-
(2009)
J. Neurosci.
, vol.29
, pp. 14869-14880
-
-
Rudrabhatla, P.1
Albers, W.2
Pant, H.C.3
-
35
-
-
78649984662
-
Regulation of protein phosphatase 2A methylation by LCMT1 and PME-1 plays a critical role in differentiation of neuroblastoma cells
-
J.M. Sontag, V. Nunbhakdi-Craig, M. Mitterhuber, E. Ogris, and E. Sontag Regulation of protein phosphatase 2A methylation by LCMT1 and PME-1 plays a critical role in differentiation of neuroblastoma cells J. Neurochem. 115 2010 1455 1465
-
(2010)
J. Neurochem.
, vol.115
, pp. 1455-1465
-
-
Sontag, J.M.1
Nunbhakdi-Craig, V.2
Mitterhuber, M.3
Ogris, E.4
Sontag, E.5
-
36
-
-
70350690313
-
Dithiolethione compounds inhibit Akt signaling in human breast and lung cancer cells by increasing PP2A activity
-
C.H. Switzer, L.A. Ridnour, R.Y. Cheng, A. Sparatore, S.P. Del, T.W. Moody, M.P. Vitek, D.D. Roberts, and D.A. Wink Dithiolethione compounds inhibit Akt signaling in human breast and lung cancer cells by increasing PP2A activity Oncogene 28 2009 3837 3846
-
(2009)
Oncogene
, vol.28
, pp. 3837-3846
-
-
Switzer, C.H.1
Ridnour, L.A.2
Cheng, R.Y.3
Sparatore, A.4
Del, S.P.5
Moody, T.W.6
Vitek, M.P.7
Roberts, D.D.8
Wink, D.A.9
-
37
-
-
2442668926
-
Hereditary early-onset Parkinson's disease caused by mutations in PINK1
-
DOI 10.1126/science.1096284
-
E.M. Valente, P.M. bou-Sleiman, V. Caputo, M.M. Muqit, K. Harvey, S. Gispert, Z. Ali, T.D. Del, A.R. Bentivoglio, D.G. Healy, A. Albanese, R. Nussbaum, R. Gonzalez-Maldonado, T. Deller, S. Salvi, P. Cortelli, W.P. Gilks, D.S. Latchman, R.J. Harvey, B. Dallapiccola, G. Auburger, and N.W. Wood Hereditary early-onset Parkinson's disease caused by mutations in PINK1 Science 304 2004 1158 1160 (Pubitemid 38661852)
-
(2004)
Science
, vol.304
, Issue.5674
, pp. 1158-1160
-
-
Valente, E.M.1
Abou-Sleiman, P.M.2
Caputo, V.3
Muqit, M.M.K.4
Harvey, K.5
Gispert, S.6
Ali, Z.7
Del Turco, D.8
Bentivoglio, A.R.9
Healy, D.G.10
Albanese, A.11
Nussbaum, R.12
Gonzalez-Maldonado, R.13
Deller, T.14
Salvi, S.15
Cortelli, P.16
Gilks, W.P.17
Latchman, D.S.18
Harvey, R.J.19
Dallapiccola, B.20
Auburger, G.21
Wood, N.W.22
more..
-
38
-
-
80052640576
-
Declining phosphatases underlie aging-related hyperphosphorylation of neurofilaments
-
doi:10.1016/j.neurobiolaging.2009.12.001
-
Veeranna, Yang, D.S., Lee, J.H., Vinod, K.Y., Stavrides, P., Amin, N.D., Pant, H.C., Nixon, R.A., 2009. Declining phosphatases underlie aging-related hyperphosphorylation of neurofilaments. Neurobiol. Aging. doi:10.1016/j. neurobiolaging.2009.12.001.
-
(2009)
Neurobiol. Aging.
-
-
Veeranna1
Yang, D.S.2
Lee, J.H.3
Vinod, K.Y.4
Stavrides, P.5
Amin, N.D.6
Pant, H.C.7
Nixon, R.A.8
-
39
-
-
75949098487
-
PINK1-dependent recruitment of Parkin to mitochondria in mitophagy
-
C. Vives-Bauza, C. Zhou, Y. Huang, M. Cui, R.L. de Vries, J. Kim, J. May, M.A. Tocilescu, W. Liu, H.S. Ko, J. Magrane, D.J. Moore, V.L. Dawson, R. Grailhe, T.M. Dawson, C. Li, K. Tieu, and S. Przedborski PINK1-dependent recruitment of Parkin to mitochondria in mitophagy Proc. Natl. Acad. Sci. USA 107 2010 378 383
-
(2010)
Proc. Natl. Acad. Sci. USA
, vol.107
, pp. 378-383
-
-
Vives-Bauza, C.1
Zhou, C.2
Huang, Y.3
Cui, M.4
De Vries, R.L.5
Kim, J.6
May, J.7
Tocilescu, M.A.8
Liu, W.9
Ko, H.S.10
Magrane, J.11
Moore, D.J.12
Dawson, V.L.13
Grailhe, R.14
Dawson, T.M.15
Li, C.16
Tieu, K.17
Przedborski, S.18
-
40
-
-
33748600694
-
Antioxidants protect PINK1-dependent dopaminergic neurons in Drosophila
-
DOI 10.1073/pnas.0604661103
-
D. Wang, L. Qian, H. Xiong, J. Liu, W.S. Neckameyer, S. Oldham, K. Xia, J. Wang, R. Bodmer, and Z. Zhang Antioxidants protect PINK1-dependent dopaminergic neurons in Drosophila Proc. Natl. Acad. Sci. USA 103 2006 13520 13525 (Pubitemid 44380140)
-
(2006)
Proceedings of the National Academy of Sciences of the United States of America
, vol.103
, Issue.36
, pp. 13520-13525
-
-
Wang, D.1
Qian, L.2
Xiong, H.3
Liu, J.4
Neckameyer, W.S.5
Oldham, S.6
Xia, K.7
Wang, J.8
Bodmer, R.9
Zhang, Z.10
-
41
-
-
35349030746
-
PINK1 mutants associated with recessive Parkinson's disease are defective in inhibiting mitochondrial release of cytochrome c
-
DOI 10.1016/j.nbd.2007.07.010, PII S0969996107001611
-
H.L. Wang, A.H. Chou, T.H. Yeh, A.H. Li, Y.L. Chen, Y.L. Kuo, S.R. Tsai, and S.T. Yu PINK1 mutants associated with recessive Parkinson's disease are defective in inhibiting mitochondrial release of cytochrome c Neurobiol. Dis. 28 2007 216 226 (Pubitemid 47615460)
-
(2007)
Neurobiology of Disease
, vol.28
, Issue.2
, pp. 216-226
-
-
Wang, H.-L.1
Chou, A.-H.2
Yeh, T.-H.3
Li, A.H.4
Chen, Y.-L.5
Kuo, Y.-L.6
Tsai, S.-R.7
Yu, S.-T.8
-
42
-
-
44949237240
-
JNK1-Mediated Phosphorylation of Bcl-2 Regulates Starvation-Induced Autophagy
-
DOI 10.1016/j.molcel.2008.06.001, PII S1097276508003894
-
Y. Wei, S. Pattingre, S. Sinha, M. Bassik, and B. Levine JNK1-mediated phosphorylation of Bcl-2 regulates starvation-induced autophagy Mol. Cell 30 2008 678 688 (Pubitemid 351818252)
-
(2008)
Molecular Cell
, vol.30
, Issue.6
, pp. 678-688
-
-
Wei, Y.1
Pattingre, S.2
Sinha, S.3
Bassik, M.4
Levine, B.5
-
43
-
-
49349087497
-
PINK1 is necessary for long term survival and mitochondrial function in human dopaminergic neurons
-
A. Wood-Kaczmar, S. Gandhi, Z. Yao, A.Y. Abramov, E.A. Miljan, G. Keen, L. Stanyer, I. Hargreaves, K. Klupsch, E. Deas, J. Downward, L. Mansfield, P. Jat, J. Taylor, S. Heales, M.R. Duchen, D. Latchman, S.J. Tabrizi, and N.W. Wood PINK1 is necessary for long term survival and mitochondrial function in human dopaminergic neurons PLoS One 3 2008 e2455
-
(2008)
PLoS One
, vol.3
, pp. 2455
-
-
Wood-Kaczmar, A.1
Gandhi, S.2
Yao, Z.3
Abramov, A.Y.4
Miljan, E.A.5
Keen, G.6
Stanyer, L.7
Hargreaves, I.8
Klupsch, K.9
Deas, E.10
Downward, J.11
Mansfield, L.12
Jat, P.13
Taylor, J.14
Heales, S.15
Duchen, M.R.16
Latchman, D.17
Tabrizi, S.J.18
Wood, N.W.19
-
44
-
-
77951214016
-
Mammalian autophagy: Core molecular machinery and signaling regulation
-
Z. Yang, and D.J. Klionsky Mammalian autophagy: core molecular machinery and signaling regulation Curr. Opin. Cell Biol. 22 2010 124 131
-
(2010)
Curr. Opin. Cell Biol.
, vol.22
, pp. 124-131
-
-
Yang, Z.1
Klionsky, D.J.2
-
45
-
-
34848871269
-
Methotrexate decreases PP2A methylation and increases tau phosphorylation in neuron
-
DOI 10.1016/j.bbrc.2007.09.060, PII S0006291X0702027X
-
S.Y. Yoon, H.I. Choi, J.E. Choi, C.A. Sul, J.M. Choi, and D.H. Kim Methotrexate decreases PP2A methylation and increases tau phosphorylation in neuron Biochem. Biophys. Res. Commun. 363 2007 811 816 (Pubitemid 47513702)
-
(2007)
Biochemical and Biophysical Research Communications
, vol.363
, Issue.3
, pp. 811-816
-
-
Yoon, S.Y.1
Choi, H.I.2
Choi, J.E.3
Sul, C.A.4
Choi, J.M.5
Kim, D.H.6
-
46
-
-
67650237693
-
Tap42-associated protein phosphatase type 2A negatively regulates induction of autophagy
-
T. Yorimitsu, C. He, K. Wang, and D.J. Klionsky Tap42-associated protein phosphatase type 2A negatively regulates induction of autophagy Autophagy 5 2009 616 624
-
(2009)
Autophagy
, vol.5
, pp. 616-624
-
-
Yorimitsu, T.1
He, C.2
Wang, K.3
Klionsky, D.J.4
-
47
-
-
44349123056
-
Transgenic mice overexpressing tyrosine-to-cysteine mutant human alpha-synuclein: A progressive neurodegenerative model of diffuse Lewy body disease
-
W. Zhou, J.B. Milder, and C.R. Freed Transgenic mice overexpressing tyrosine-to-cysteine mutant human alpha-synuclein: a progressive neurodegenerative model of diffuse Lewy body disease J. Biol. Chem. 283 2008 9863 9870
-
(2008)
J. Biol. Chem.
, vol.283
, pp. 9863-9870
-
-
Zhou, W.1
Milder, J.B.2
Freed, C.R.3
-
48
-
-
33845291508
-
Negative regulation of Akt activity by p38αMAP kinase in cardiomyocytes involves membrane localization of PP2A through interaction with caveolin-1
-
DOI 10.1016/j.cellsig.2006.05.032, PII S0898656806001355
-
S. Zuluaga, A. Alvarez-Barrientos, A. Gutierrez-Uzquiza, M. Benito, A.R. Nebreda, and A. Porras Negative regulation of Akt activity by p38alpha MAP kinase in cardiomyocytes involves membrane localization of PP2A through interaction with caveolin-1 Cell. Signal. 19 2007 62 74 (Pubitemid 44880243)
-
(2007)
Cellular Signalling
, vol.19
, Issue.1
, pp. 62-74
-
-
Zuluaga, S.1
Alvarez-Barrientos, A.2
Gutierrez-Uzquiza, A.3
Benito, M.4
Nebreda, A.R.5
Porras, A.6
|