Direct binding of PP2A to Sprouty2 and phosphorylation changes are a prerequisite for ERK inhibition downstream of fibroblast growth factor receptor stimulation

Journal of Biological Chemistry

Volumn 282, Issue 12, 2007, Pages 9117-9126

  Lao, Dieu Hung ^a   Yusoff, Permeen ^a   Chandramouli, Sumana ^a   Philp, Robin J ^b   Chee, Wai Fong ^a   Jackson, Rebecca A ^a   Tzuen, Yih Saw ^a   Chye, Yun Yu ^a   Guy, Graeme R ^a  

^a INSTITUTE OF MOLECULAR AND CELL BIOLOGY   (Singapore)

^b AGENCY FOR SCIENCE   (Singapore)

Author keywords

[No Author keywords available]

Indexed keywords

DEPHOSPHORYLATION; FIBROBLAST GROWTH FACTOR; RECEPTOR STIMULATION;

CELL GROWTH; ENZYME INHIBITION; GENE EXPRESSION; PHOSPHORYLATION; PRECIPITATES;

FIBROBLASTS;

CBL PROTEIN; FIBROBLAST GROWTH FACTOR RECEPTOR; FIBROBLAST GROWTH FACTOR RECEPTOR 1; ISOENZYME; MITOGEN ACTIVATED PROTEIN KINASE; PHOSPHOPROTEIN PHOSPHATASE 2A; PROTEIN PHOSPHATASE 2AA; PROTEIN PHOSPHATASE 2AC; RAS PROTEIN; SERINE; SPROUTY PROTEIN; SPROUTY PROTEIN 2; TYROSINE; UNCLASSIFIED DRUG; PHOSPHOPROTEIN PHOSPHATASE; SIGNAL PEPTIDE; SPRY2 PROTEIN, HUMAN;

AMINO ACID SEQUENCE; AMINO TERMINAL SEQUENCE; ARTICLE; CARBOXY TERMINAL SEQUENCE; CONTROLLED STUDY; EMBRYO; ENZYME ACTIVITY; ENZYME INHIBITION; ENZYME MECHANISM; ENZYME PHOSPHORYLATION; HUMAN; HUMAN CELL; IMMUNOPRECIPITATION; POLYACRYLAMIDE GEL ELECTROPHORESIS; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN BINDING; PROTEIN DEPHOSPHORYLATION; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN MOTIF; PROTEIN PROTEIN INTERACTION; REGULATORY MECHANISM; SIGNAL TRANSDUCTION; ANIMAL; CELL STRAIN; CHEMISTRY; METABOLISM; MOLECULAR GENETICS; PHOSPHORYLATION; RAT; SEQUENCE HOMOLOGY;

AMINO ACID SEQUENCE; ANIMALS; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; HUMANS; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; MOLECULAR SEQUENCE DATA; PC12 CELLS; PHOSPHOPROTEIN PHOSPHATASE; PHOSPHORYLATION; PROTEIN BINDING; PROTO-ONCOGENE PROTEINS C-CBL; RATS; RECEPTORS, FIBROBLAST GROWTH FACTOR; SEQUENCE HOMOLOGY, AMINO ACID; SIGNAL TRANSDUCTION;

EID: 34247866596     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M607563200     Document Type: Article

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