-
1
-
-
39049149816
-
The role of mitochondria in apoptosis
-
Jeong, S. Y. and Seol, D. W. (2008) The role of mitochondria in apoptosis. BMB Rep. 41, 11-22.
-
(2008)
BMB Rep
, vol.41
, pp. 11-22
-
-
Jeong, S.Y.1
Seol, D.W.2
-
2
-
-
67650868959
-
Mitochondrial dynamics in mammalian health and disease
-
Liesa, M., Palacín, M. and Zorzano, A. (2009) Mitochondrial dynamics in mammalian health and disease. Physiol. Rev. 89, 799-845.
-
(2009)
Physiol. Rev.
, vol.89
, pp. 799-845
-
-
Liesa, M.1
Palacín, M.2
Zorzano, A.3
-
3
-
-
0344413426
-
Mitochondrial fission in apoptosis, neurodegeneration and aging
-
Bossy-Wetzel, E., Barsoum, M. J., Godzik, A., Schwarzenbacher, R. and Lipton, S. A. (2003) Mitochondrial fission in apoptosis, neurodegeneration and aging. Curr. Opin. Cell Biol. 15, 706-716.
-
(2003)
Curr. Opin. Cell Biol.
, vol.15
, pp. 706-716
-
-
Bossy-Wetzel, E.1
Barsoum, M.J.2
Godzik, A.3
Schwarzenbacher, R.4
Lipton, S.A.5
-
4
-
-
33745274726
-
Mitochondria: dynamic organelles in disease, aging, and development
-
Chan, D. C. (2006) Mitochondria: dynamic organelles in disease, aging, and development. Cell 125, 1241-1252.
-
(2006)
Cell
, vol.125
, pp. 1241-1252
-
-
Chan, D.C.1
-
5
-
-
60249086345
-
Mitochondrial dynamics and cancer
-
Grandemange, S., Herzig, S. and Martinou, J. C. (2009)Mitochondrial dynamics and cancer. Semin. Cancer Biol. 19, 50-56.
-
(2009)
Semin. Cancer Biol.
, vol.19
, pp. 50-56
-
-
Grandemange, S.1
Herzig, S.2
Martinou, J.C.3
-
6
-
-
77957358299
-
Mitochondrial dynamics in cell death and neurodegeneration
-
Cho, D. H., Nakamura, T. and Lipton, S. A. (2010) Mitochondrial dynamics in cell death and neurodegeneration. Cell. Mol. Life Sci. 67, 3435-3447.
-
(2010)
Cell. Mol. Life Sci.
, vol.67
, pp. 3435-3447
-
-
Cho, D.H.1
Nakamura, T.2
Lipton, S.A.3
-
7
-
-
0035166814
-
Dynamin-related protein Drp1 is required for mitochondrial division in mammalian cells
-
Smirnova, E., Griparic, L., Shurland, D. L. and van der Bliek, A. M. (2001) Dynamin-related protein Drp1 is required for mitochondrial division in mammalian cells. Mol. Biol. Cell 12, 2245-2256.
-
(2001)
Mol. Biol. Cell
, vol.12
, pp. 2245-2256
-
-
Smirnova, E.1
Griparic, L.2
Shurland, D.L.3
van der Bliek, A.M.4
-
8
-
-
0035166812
-
Mammalian dynamin-like protein DLP1 tubulates membranes
-
Yoon, Y., Pitts, K. R. and McNiven, M. A. (2001) Mammalian dynamin-like protein DLP1 tubulates membranes. Mol. Biol. Cell 12, 2894-2905.
-
(2001)
Mol. Biol. Cell
, vol.12
, pp. 2894-2905
-
-
Yoon, Y.1
Pitts, K.R.2
McNiven, M.A.3
-
9
-
-
0035487808
-
The role of dynamin-related protein 1, a mediator of mitochondrial fission, in apoptosis
-
Frank, S., Gaume, B., Bergmann-Leitner, E. S., Leitner, W. W., Robert, E. G., Catez, F., Smith, C. L. and Youle, R. J. The role of dynamin-related protein 1, a mediator of mitochondrial fission, in apoptosis. Dev. Cell 1, 515-525.
-
Dev. Cell
, vol.1
, pp. 515-525
-
-
Frank, S.1
Gaume, B.2
Bergmann-Leitner, E.S.3
Leitner, W.W.4
Robert, E.G.5
Catez, F.6
Smith, C.L.7
Youle, R.J.8
-
10
-
-
56349103980
-
The molecular mechanism of mitochondrial fusion
-
Hoppins, S. and Nunnari, J. (2009) The molecular mechanism of mitochondrial fusion. Biochim. Biophys. Acta. 1793, 20-26.
-
(2009)
Biochim. Biophys. Acta.
, vol.1793
, pp. 20-26
-
-
Hoppins, S.1
Nunnari, J.2
-
11
-
-
0037424239
-
Loss of OPA1 perturbates the mitochondrial inner membrane structure and integrity, leading to cytochrome c release and apoptosis
-
Olichon, A., Baricault, L., Gas, N., Guillou, E., Valette, A., Belenguer, P. and Lenaers, G. (2003) Loss of OPA1 perturbates the mitochondrial inner membrane structure and integrity, leading to cytochrome c release and apoptosis. J. Biol. Chem. 278, 7743-7746.
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 7743-7746
-
-
Olichon, A.1
Baricault, L.2
Gas, N.3
Guillou, E.4
Valette, A.5
Belenguer, P.6
Lenaers, G.7
-
12
-
-
45349094984
-
Mitochondrial dynamics and apoptosis
-
Suen, D. F., Norris, K. L. and Youle, R. J. (2008) Mitochondrial dynamics and apoptosis. Genes Dev. 22, 1577-1590.
-
(2008)
Genes Dev
, vol.22
, pp. 1577-1590
-
-
Suen, D.F.1
Norris, K.L.2
Youle, R.J.3
-
13
-
-
50949115617
-
High levels of Fis1, a pro-fission mitochondrial protein, trigger autophagy
-
Gomes, L. C. and Scorrano, L. (2008) High levels of Fis1, a pro-fission mitochondrial protein, trigger autophagy. Biochim. Biophys. Acta. 1777, 860-866.
-
(2008)
Biochim. Biophys. Acta.
, vol.1777
, pp. 860-866
-
-
Gomes, L.C.1
Scorrano, L.2
-
14
-
-
38549110110
-
Fission and selective fusion govern mitochondrial segregation and elimination by autophagy
-
Twig, G., Elorza, A., Molina, A. J., Mohamed, H., Wikstrom, J. D., Walzer, G., Stiles, L., Haigh, S. E., Katz, S., Las, G., Alroy, J., Wu, M., Py, B. F., Yuan, J., Deeney, J. T., Corkey, B. E. and Shirihai, O. S. (2008) Fission and selective fusion govern mitochondrial segregation and elimination by autophagy. EMBO J. 27, 433-446
-
(2008)
EMBO J
, vol.27
, pp. 433-446
-
-
Twig, G.1
Elorza, A.2
Molina, A.J.3
Mohamed, H.4
Wikstrom, J.D.5
Walzer, G.6
Stiles, L.7
Haigh, S.E.8
Katz, S.9
Las, G.10
Alroy, J.11
Wu, M.12
Py, B.F.13
Yuan, J.14
Deeney, J.T.15
Corkey, B.E.16
Shirihai, O.S.17
-
15
-
-
38849099158
-
Chemical inhibition of the mitochondrial division dynamin reveals its role in Bax/Bak-dependent mitochondrial outer membrane permeabilization
-
Cassidy-Stone, A., Chipuk, J. E., Ingerman, E., Song, C., Yoo, C., Kuwana, T., Kurth, M. J., Shaw, J. T., Hinshaw, J. E., Green, D. R. and Nunnari, J. (2008) Chemical inhibition of the mitochondrial division dynamin reveals its role in Bax/Bak-dependent mitochondrial outer membrane permeabilization. Dev. Cell 14, 193-204.
-
(2008)
Dev. Cell
, vol.14
, pp. 193-204
-
-
Cassidy-Stone, A.1
Chipuk, J.E.2
Ingerman, E.3
Song, C.4
Yoo, C.5
Kuwana, T.6
Kurth, M.J.7
Shaw, J.T.8
Hinshaw, J.E.9
Green, D.R.10
Nunnari, J.11
-
16
-
-
33749265862
-
Formation of elongated giant mitochondria in DFO-induced cellular senescence: involvement of enhanced fusion process through modulation of Fis1
-
Yoon, Y. S., Yoon, D. S., Lim, I. K., Yoon, S. H., Chung, H. Y., Rojo, M., Malka, F., Jou, M. J., Martinou, J. C. and Yoon, G. S. (2006) Formation of elongated giant mitochondria in DFO-induced cellular senescence: involvement of enhanced fusion process through modulation of Fis1. Cell Physiol. 209, 468-480.
-
(2006)
Cell Physiol
, vol.209
, pp. 468-480
-
-
Yoon, Y.S.1
Yoon, D.S.2
Lim, I.K.3
Yoon, S.H.4
Chung, H.Y.5
Rojo, M.6
Malka, F.7
Jou, M.J.8
Martinou, J.C.9
Yoon, G.S.10
-
17
-
-
77950212486
-
Antineoplastic mechanisms of niclosamide in acute myelogenous leukemia stem cells: inactivation of the NF-kappaB pathway and generation of reactive oxygen species
-
Jin, Y., Lu, Z., Ding, K., Li, J., Du, X., Chen, C., Sun, X., Wu, Y., Zhou, J. and Pan, J. (2010) Antineoplastic mechanisms of niclosamide in acute myelogenous leukemia stem cells: inactivation of the NF-kappaB pathway and generation of reactive oxygen species. Cancer Res. 70, 2516-2527.
-
(2010)
Cancer Res
, vol.70
, pp. 2516-2527
-
-
Jin, Y.1
Lu, Z.2
Ding, K.3
Li, J.4
Du, X.5
Chen, C.6
Sun, X.7
Wu, Y.8
Zhou, J.9
Pan, J.10
-
18
-
-
32144451844
-
Catalysis of NADH→NADP+ transhydrogenation by adult Hymenolepis diminuta mitochondria
-
Park, J. P. and Fioravanti, C. F. (2006) Catalysis of NADH→NADP+ transhydrogenation by adult Hymenolepis diminuta mitochondria. Parasitol. Res. 98, 200-206.
-
(2006)
Parasitol. Res.
, vol.98
, pp. 200-206
-
-
Park, J.P.1
Fioravanti, C.F.2
-
19
-
-
70349616273
-
Screen for chemical modulators of autophagy reveals novel therapeutic inhibitors of mTORC1 signaling
-
Balgi, A. D., Fonseca, B. D., Donohue, E., Tsang, T. C., Lajoie, P., Proud, C. G., Nabi, I. R. and Roberge, M. (2009) Screen for chemical modulators of autophagy reveals novel therapeutic inhibitors of mTORC1 signaling. PLoS One 22, e7124.
-
(2009)
PLoS One
, vol.22
-
-
Balgi, A.D.1
Fonseca, B.D.2
Donohue, E.3
Tsang, T.C.4
Lajoie, P.5
Proud, C.G.6
Nabi, I.R.7
Roberge, M.8
-
20
-
-
70149097538
-
The molecular machinery of mitochondrial fusion and fission: an opportunity for drug discovery
-
Zorzano, A., Sebastián, D., Segalés, J. and Palacín, M. (2009) The molecular machinery of mitochondrial fusion and fission: an opportunity for drug discovery. Curr. Opin. Drug Discov. Devel. 12, 597-606.
-
(2009)
Curr. Opin. Drug Discov. Devel.
, vol.12
, pp. 597-606
-
-
Zorzano, A.1
Sebastián, D.2
Segalés, J.3
Palacín, M.4
-
21
-
-
34347386472
-
Thapsigargin induces biphasic fragmentation of mitochondria through calcium-mediated mitochondrial fission and apoptosis
-
Hom, J. R., Gewandter, J. S., Michael, L., Sheu, S. S. and Yoon, Y. (2007) Thapsigargin induces biphasic fragmentation of mitochondria through calcium-mediated mitochondrial fission and apoptosis. J. Cell Physiol. 212, 498-508.
-
(2007)
J. Cell Physiol.
, vol.212
, pp. 498-508
-
-
Hom, J.R.1
Gewandter, J.S.2
Michael, L.3
Sheu, S.S.4
Yoon, Y.5
-
22
-
-
77955485416
-
The Bcl-2 homology domain 3 mimetic gossypol induces both Beclin 1-dependent and Beclin 1-independent cytoprotective autophagy in cancer cells
-
Gao, P., Bauvy, C., Souquère, S., Tonelli, G., Liu, L., Zhu, Y., Qiao, Z., Bakula, D., Proikas-Cezanne, T., Pierron, G., Codogno, P., Chen, Q. and Mehrpour, M. (2010) The Bcl-2 homology domain 3 mimetic gossypol induces both Beclin 1-dependent and Beclin 1-independent cytoprotective autophagy in cancer cells. J. Biol. Chem. 285, 2570-2581.
-
(2010)
J. Biol. Chem.
, vol.285
, pp. 2570-2581
-
-
Gao, P.1
Bauvy, C.2
Souquère, S.3
Tonelli, G.4
Liu, L.5
Zhu, Y.6
Qiao, Z.7
Bakula, D.8
Proikas-Cezanne, T.9
Pierron, G.10
Codogno, P.11
Chen, Q.12
Mehrpour, M.13
-
23
-
-
70350489312
-
The anti-helminthic niclosamide inhibits Wnt/Frizzled1 signaling
-
Chen, M., Wang, J., Lu, J., Bond, M. C., Ren, X. R., Lyerly, H. K., Barak, L. S. and Chen, W. (2009) The anti-helminthic niclosamide inhibits Wnt/Frizzled1 signaling. Biochemistry 48, 10267-10274.
-
(2009)
Biochemistry
, vol.48
, pp. 10267-10274
-
-
Chen, M.1
Wang, J.2
Lu, J.3
Bond, M.C.4
Ren, X.R.5
Lyerly, H.K.6
Barak, L.S.7
Chen, W.8
-
24
-
-
77649300605
-
Toxicity of a novel suspension concentrate of niclosamide against Biomphalaria glabrata
-
Dai, J. R., Coles, G. C., Wang, W. and Liang, Y. S. (2010) Toxicity of a novel suspension concentrate of niclosamide against Biomphalaria glabrata. Trans. R. Soc. Trop. Med. Hyg. 104, 304-306.
-
(2010)
Trans. R. Soc. Trop. Med. Hyg.
, vol.104
, pp. 304-306
-
-
Dai, J.R.1
Coles, G.C.2
Wang, W.3
Liang, Y.S.4
-
25
-
-
0035839065
-
The protonophore CCCP induces mitochondrial permeability transition without cytochrome c release in human osteosarcoma cells
-
Lim, M. L., Minamikawa, T. and Nagley, P. (2001) The protonophore CCCP induces mitochondrial permeability transition without cytochrome c release in human osteosarcoma cells. FEBS Lett. 503, 69-74.
-
(2001)
FEBS Lett
, vol.503
, pp. 69-74
-
-
Lim, M.L.1
Minamikawa, T.2
Nagley, P.3
-
26
-
-
0036906665
-
Mitochondrial fusion in human cells is efficient, requires the inner membrane potential, and is mediated by mitofusins
-
Legros, F., Lombès, A., Frachon, P. and Rojo, M. (2002) Mitochondrial fusion in human cells is efficient, requires the inner membrane potential, and is mediated by mitofusins. Mol. Biol. Cell 13, 4343-4354.
-
(2002)
Mol. Biol. Cell
, vol.13
, pp. 4343-4354
-
-
Legros, F.1
Lombès, A.2
Frachon, P.3
Rojo, M.4
-
27
-
-
33746895175
-
Mitochondria as therapeutic targets for cancer chemotherapy
-
Galluzzi, L., Larochette, N., Zamzami, N. and Kroemer, G. (2006) Mitochondria as therapeutic targets for cancer chemotherapy. Oncogene 25, 4812-4830.
-
(2006)
Oncogene
, vol.25
, pp. 4812-4830
-
-
Galluzzi, L.1
Larochette, N.2
Zamzami, N.3
Kroemer, G.4
-
28
-
-
43449108570
-
Deregulation of the mitochondrial apoptotic machinery and development of molecular targeted drugs in acute myeloid leukemia
-
Del Poeta, G., Bruno, A., Del Principe, M. I., Venditti, A., Maurillo, L., Buccisano, F., Stasi, R., Neri, B., Luciano, F., Siniscalchi, A., de Fabritiis, P. and Amadori, S. (2008) Deregulation of the mitochondrial apoptotic machinery and development of molecular targeted drugs in acute myeloid leukemia. Curr. Cancer Drug Targets 8, 207-222.
-
(2008)
Curr. Cancer Drug Targets
, vol.8
, pp. 207-222
-
-
Del Poeta, G.1
Bruno, A.2
Del Principe, M.I.3
Venditti, A.4
Maurillo, L.5
Buccisano, F.6
Stasi, R.7
Neri, B.8
Luciano, F.9
Siniscalchi, A.10
de Fabritiis, P.11
Amadori, S.12
-
29
-
-
7744235672
-
Death by design: apoptosis, necrosis and autophagy
-
Edinger, A. L. and Thompson C. B. (2004) Death by design: apoptosis, necrosis and autophagy. Curr. Opin. Cell Biol. 16, 663-669.
-
(2004)
Curr. Opin. Cell Biol.
, vol.16
, pp. 663-669
-
-
Edinger, A.L.1
Thompson, C.B.2
-
30
-
-
34250753161
-
Cell death modalities: classification and pathophysiological implications
-
Galluzzi, L., Maiuri, M. C., Vitale, I., Zischka, H., Castedo, M., Zitvogel, L. and Kroemer, G. (2007) Cell death modalities: classification and pathophysiological implications. Cell Death Differ. 14, 1237-1243.
-
(2007)
Cell Death Differ
, vol.14
, pp. 1237-1243
-
-
Galluzzi, L.1
Maiuri, M.C.2
Vitale, I.3
Zischka, H.4
Castedo, M.5
Zitvogel, L.6
Kroemer, G.7
-
31
-
-
78650819064
-
Niclosamide prevents the formation of large ubiquitin-containing aggregates caused by proteasome inhibition
-
Gies, E., Wilde, I., Winget, J. M., Brack, M., Rotblat, B., Novoa, C. A., Balgi, A. D., Sorensen, P. H., Roberge, M. and Mayor, T. (2010) Niclosamide prevents the formation of large ubiquitin-containing aggregates caused by proteasome inhibition. PLoS One 5, e14410.
-
(2010)
PLoS One
, vol.5
-
-
Gies, E.1
Wilde, I.2
Winget, J.M.3
Brack, M.4
Rotblat, B.5
Novoa, C.A.6
Balgi, A.D.7
Sorensen, P.H.8
Roberge, M.9
Mayor, T.10
|