Niclosamide prevents the formation of large ubiquitin-containing aggregates caused by proteasome inhibition

PLoS ONE

Volumn 5, Issue 12, 2010, Pages

  Gies, Esther ^a   Wilde, Inga ^a   Winget, Jason M ^a   Brack, Maria ^a   Rotblat, Barak ^a,b   Novoa, Carolina Arias ^a   Balgi, Aruna D ^a   Sorensen, Poul H ^a,b   Roberge, Michel ^a   Mayor, Thibault ^a  

^a UNIVERSITY OF BRITISH COLUMBIA   (Canada)

^b BRITISH COLUMBIA CANCER RESEARCH CENTRE   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

MAMMALIAN TARGET OF RAPAMYCIN COMPLEX 1; NICLOSAMIDE; PROTEASOME; PROTEIN P62; RAPAMYCIN; ANTINEMATODAL AGENT; GREEN FLUORESCENT PROTEIN; MTORC1 COMPLEX, HUMAN; PROTEIN; UBIQUITIN;

ARTICLE; AUTOPHAGY; CELL INCLUSION; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG MECHANISM; ENZYME INHIBITION; LYSOSOME; NEUROBLASTOMA CELL; PROTEIN AGGREGATION; PROTEIN LOCALIZATION; QUANTITATIVE ANALYSIS; TISSUE CULTURE CELL; UBIQUITINATION; CHEMISTRY; DEGENERATIVE DISEASE; HUMAN; METABOLISM; MICROTUBULE; PROTEIN BINDING; SOLUBILITY;

ANTINEMATODAL AGENTS; AUTOPHAGY; GREEN FLUORESCENT PROTEINS; HUMANS; LYSOSOMES; MICROTUBULES; NEURODEGENERATIVE DISEASES; NICLOSAMIDE; PROTEASOME ENDOPEPTIDASE COMPLEX; PROTEIN BINDING; PROTEINS; SIROLIMUS; SOLUBILITY; UBIQUITIN;

EID: 78650819064     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0014410     Document Type: Article

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