Administration of simvastatin after kainic acid-induced status epilepticus restrains chronic temporal lobe epilepsy

PLoS ONE

Volumn 6, Issue 9, 2011, Pages

  Xie, Chuncheng ^a   Sun, Jiahang ^b   Qiao, Weidong ^a   Lu, Dunyue ^c   Wei, Lanlan ^d   Na, Meng ^a   Song, Yuanyuan ^a   Hou, Xiaohua ^a   Lin, Zhiguo ^a  

^a THE FIRST AFFILIATED HOSPITAL OF HARBIN MEDICAL UNIVERSITY   (China)

^b THE SECOND AFFILIATED HOSPITAL OF HARBIN MEDICAL UNIVERSITY   (China)

^c SUNY DOWNSTATE MEDICAL CENTER   (United States)

^d HARBIN MEDICAL UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

GLIAL FIBRILLARY ACIDIC PROTEIN; INTERLEUKIN 1BETA; KAINIC ACID; SIMVASTATIN; SODIUM CHLORIDE; TUMOR NECROSIS FACTOR ALPHA; AMINO ACID RECEPTOR STIMULATING AGENT; CYTOKINE; HYPOCHOLESTEROLEMIC AGENT;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTICONVULSANT ACTIVITY; ARTICLE; ASTROCYTOSIS; CONTROLLED STUDY; DENTATE HILUS; DRUG EFFECT; ELECTROENCEPHALOGRAPHY; EPILEPTIC STATE; HIPPOCAMPAL CA3 REGION; HIPPOCAMPUS; INTERNEURON; MALE; MOSSY FIBER; NERVE SPROUTING; NONHUMAN; PROTEIN EXPRESSION; PYRAMIDAL NERVE CELL; RAT; TEMPORAL LOBE EPILEPSY; ANIMAL; ANIMAL BEHAVIOR; CHEMICALLY INDUCED DISORDER; CHRONIC DISEASE; ENZYME LINKED IMMUNOSORBENT ASSAY; HIPPOCAMPAL MOSSY FIBER; METABOLISM; NERVE CELL; PATHOLOGY; PATHOPHYSIOLOGY; WISTAR RAT;

ANIMALIA; RATTUS;

ANIMALS; ANTICHOLESTEREMIC AGENTS; BEHAVIOR, ANIMAL; CHRONIC DISEASE; CYTOKINES; ENZYME-LINKED IMMUNOSORBENT ASSAY; EPILEPSY, TEMPORAL LOBE; EXCITATORY AMINO ACID AGONISTS; KAINIC ACID; MALE; MOSSY FIBERS, HIPPOCAMPAL; NEURONS; RATS; RATS, WISTAR; SIMVASTATIN; STATUS EPILEPTICUS;

EID: 80052870742     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0024966     Document Type: Article

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