Long-term benefits after treatment of traumatic brain injury with simvastatin in rats

Neurosurgery

Volumn 65, Issue 1, 2009, Pages 187-191

  Mahmood, Asim ^a   Goussev, Anton ^a   Kazmi, Humaira ^a   Qu, Changsheng ^a   Lu, Dunyue ^b   Chopp, Michael ^a,c  

^a HENRY FORD HOSPITAL   (United States)

^b SUNY DOWNSTATE MEDICAL CENTER   (United States)

^c OAKLAND UNIVERSITY   (United States)

Author keywords

Long term; Newly generated cells; Simvastatin; Traumatic brain injury

Indexed keywords

BRAIN DERIVED NEUROTROPHIC FACTOR; PHOSPHATE BUFFERED SALINE; SIMVASTATIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN CORTEX; CONTROLLED STUDY; DRUG DOSE COMPARISON; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; HIPPOCAMPUS; IMMUNOHISTOCHEMISTRY; INJURY SEVERITY; LONG TERM CARE; NONHUMAN; OUTCOME ASSESSMENT; PRIORITY JOURNAL; RAT; TRAUMATIC BRAIN INJURY; TREATMENT DURATION;

ANIMALS; BRAIN INJURIES; BRAIN-DERIVED NEUROTROPHIC FACTOR; DISEASE MODELS, ANIMAL; DOSE-RESPONSE RELATIONSHIP, DRUG; ENZYME-LINKED IMMUNOSORBENT ASSAY; FEMALE; HIPPOCAMPUS; HYDROXYMETHYLGLUTARYL-COA REDUCTASE INHIBITORS; NEURONS; RATS; RATS, WISTAR; SIMVASTATIN; TIME FACTORS;

EID: 67651167055     PISSN: 0148396X     EISSN: None     Source Type: Journal    
DOI: 10.1227/01.NEU.0000343540.24780.D6     Document Type: Article

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