-
1
-
-
0035909112
-
Judging a protein by more than its name: GSK-3
-
Woodgett JR. Judging a protein by more than its name: GSK-3. Sci STKE 2001, 100:re12.
-
(2001)
Sci STKE
, vol.100
-
-
Woodgett, J.R.1
-
2
-
-
27144557493
-
Endoplasmic reticulum stress accelerates p53 degradation by the cooperative actions of Hdm2 and glycogen synthase kinase 3 beta
-
Pluquet O, Qu LK, Baltzis D, Koromilas AE. Endoplasmic reticulum stress accelerates p53 degradation by the cooperative actions of Hdm2 and glycogen synthase kinase 3 beta. Mol Cell Biol 2005, 21:9392-405.
-
(2005)
Mol Cell Biol
, vol.21
, pp. 9392-9405
-
-
Pluquet, O.1
Qu, L.K.2
Baltzis, D.3
Koromilas, A.E.4
-
3
-
-
4644354440
-
Control of tumor suppressor p53 function by endoplasmic stress
-
Qu L, Koromilas AE. Control of tumor suppressor p53 function by endoplasmic stress. Cell Cycle 2004, 3:567-70.
-
(2004)
Cell Cycle
, vol.3
, pp. 567-570
-
-
Qu, L.1
Koromilas, A.E.2
-
4
-
-
33748299477
-
The paradoxical pro- and anti-apoptotic actions of GSK3 in the intrinsic and extrinsic apoptosis signaling pathways
-
Beurel E, Jope RS. The paradoxical pro- and anti-apoptotic actions of GSK3 in the intrinsic and extrinsic apoptosis signaling pathways. Progress in Neurobiol 2006, 79:173-98.
-
(2006)
Progress in Neurobiol
, vol.79
, pp. 173-198
-
-
Beurel, E.1
Jope, R.S.2
-
5
-
-
2542425324
-
Glycogen synthase kinase-3β suppression eliminates tumor necrosis factor-related apoptosis-inducing ligand resistance in prostate cancer
-
Liao X, Zhang L, Thrasher JB, Du J, Li B. Glycogen synthase kinase-3β suppression eliminates tumor necrosis factor-related apoptosis-inducing ligand resistance in prostate cancer. Mol Cancer Ther 2003, 2:1215-22.
-
(2003)
Mol Cancer Ther
, vol.2
, pp. 1215-1222
-
-
Liao, X.1
Zhang, L.2
Thrasher, J.B.3
Du, J.4
Li, B.5
-
6
-
-
17844403720
-
Inhibition of GSK3 protects cells from intrinsic but not extrinsic oxidative stress
-
King TD, Jope RS. Inhibition of GSK3 protects cells from intrinsic but not extrinsic oxidative stress. Neuroreport 2005, 16:597-601.
-
(2005)
Neuroreport
, vol.16
, pp. 597-601
-
-
King, T.D.1
Jope, R.S.2
-
7
-
-
53049093524
-
Glycogen synthase kinase-3 inhibition induces glioma cell death through c-myc, nuclear factor-κB, and glucose regulation
-
Kotliarova S, Pastorino S, Kovell LC, Kotliarov Y, Song H, Zhang W, Bailey R, Maric D, Zenklusen JC, Lee J, Fine HA. Glycogen synthase kinase-3 inhibition induces glioma cell death through c-myc, nuclear factor-κB, and glucose regulation. Cancer Res 2008, 68:6643-51.
-
(2008)
Cancer Res
, vol.68
, pp. 6643-6651
-
-
Kotliarova, S.1
Pastorino, S.2
Kovell, L.C.3
Kotliarov, Y.4
Song, H.5
Zhang, W.6
Bailey, R.7
Maric, D.8
Zenklusen, J.C.9
Lee, J.10
Fine, H.A.11
-
8
-
-
45549104364
-
P53 stabilization in response to DNA damage requires Akt/PKB and DNA-PK
-
Boehme KA, Kulikov R, Blattner C. p53 stabilization in response to DNA damage requires Akt/PKB and DNA-PK. Proc Natl Acad Sci USA 2008, 105:7785-90.
-
(2008)
Proc Natl Acad Sci USA
, vol.105
, pp. 7785-7790
-
-
Boehme, K.A.1
Kulikov, R.2
Blattner, C.3
-
9
-
-
65449154815
-
Ablation of key oncogenic pathways by RITA-reactivated p53 is required for efficient apoptosis
-
Grinkevich VV, Nikulenkov F, Shi Y, Enge M, Bao W, Maljukova A, Gluch A, Kel A, Sangfelt O, Selivanova G. Ablation of key oncogenic pathways by RITA-reactivated p53 is required for efficient apoptosis. Cancer Cell 2009, 15:441-53.
-
(2009)
Cancer Cell
, vol.15
, pp. 441-453
-
-
Grinkevich, V.V.1
Nikulenkov, F.2
Shi, Y.3
Enge, M.4
Bao, W.5
Maljukova, A.6
Gluch, A.7
Kel, A.8
Sangfelt, O.9
Selivanova, G.10
-
10
-
-
33644855216
-
Glycogen synthase kinase-3 regulates mitochondrial outer membrane permeabilization and apoptosis by destabilization of MCL-1
-
Maurer U, Charvet C, Wagman AS, Dejardin E, Green DR. Glycogen synthase kinase-3 regulates mitochondrial outer membrane permeabilization and apoptosis by destabilization of MCL-1. Mol Cell 2006, 21:749-60.
-
(2006)
Mol Cell
, vol.21
, pp. 749-760
-
-
Maurer, U.1
Charvet, C.2
Wagman, A.S.3
Dejardin, E.4
Green, D.R.5
-
12
-
-
0034818446
-
Post-translational modifications and activation of p53 by genotoxic stresses
-
Appella E, Anderson CW. Post-translational modifications and activation of p53 by genotoxic stresses. Eur J Biochem 2001, 268:2764-72.
-
(2001)
Eur J Biochem
, vol.268
, pp. 2764-2772
-
-
Appella, E.1
Anderson, C.W.2
-
13
-
-
0032192140
-
The complexity of p53 modulation: emerging patterns from divergent signals
-
Giaccia AJ, Kastan MB. The complexity of p53 modulation: emerging patterns from divergent signals. Genes Dev 1998, 12:2973-83.
-
(1998)
Genes Dev
, vol.12
, pp. 2973-2983
-
-
Giaccia, A.J.1
Kastan, M.B.2
-
14
-
-
0038146962
-
ATR/ATM targets are phosphorylated by ATR in response to hypoxia and ATM in response to reoxygenation
-
Hammond EM, Dorie MJ, Giaccia AJ. ATR/ATM targets are phosphorylated by ATR in response to hypoxia and ATM in response to reoxygenation. J Biol Chem 2003, 278:12207-13.
-
(2003)
J Biol Chem
, vol.278
, pp. 12207-12213
-
-
Hammond, E.M.1
Dorie, M.J.2
Giaccia, A.J.3
-
15
-
-
0030667702
-
DNA damage-induced phosphorylation of p53 alleviates inhibition by MDM2
-
Shieh SY, Ikeda M, Taya Y, Prives C. DNA damage-induced phosphorylation of p53 alleviates inhibition by MDM2. Cell 1997, 91:325-34.
-
(1997)
Cell
, vol.91
, pp. 325-334
-
-
Shieh, S.Y.1
Ikeda, M.2
Taya, Y.3
Prives, C.4
-
16
-
-
0030797585
-
Activation of p53 sequence-specific DNA binding by acetylation of the p53 C-terminal domain
-
Gu W, Roeder RG. Activation of p53 sequence-specific DNA binding by acetylation of the p53 C-terminal domain. Cell 1997, 90:595-606.
-
(1997)
Cell
, vol.90
, pp. 595-606
-
-
Gu, W.1
Roeder, R.G.2
-
17
-
-
35748960252
-
The eIF2 alpha kinases PERK and PKR activate glycogen synthase kinase 3 to promote the proteasomal degradation of p53
-
Baltzis D, Pluquet O, Papadakis AI, Kazemi S, Qu LK, Koromilas AE. The eIF2 alpha kinases PERK and PKR activate glycogen synthase kinase 3 to promote the proteasomal degradation of p53. J Biol Chem 2007, 282:31675-87.
-
(2007)
J Biol Chem
, vol.282
, pp. 31675-31687
-
-
Baltzis, D.1
Pluquet, O.2
Papadakis, A.I.3
Kazemi, S.4
Qu, L.K.5
Koromilas, A.E.6
-
18
-
-
20444475324
-
Activation of p53-dependent apoptosis by acute ablation of glycogen synthase kinase-3 beta in colorectal cancer cells
-
Ghosh JC, Altieri DC. Activation of p53-dependent apoptosis by acute ablation of glycogen synthase kinase-3 beta in colorectal cancer cells. Clin Cancer Res 2005, 11:4580-8.
-
(2005)
Clin Cancer Res
, vol.11
, pp. 4580-4588
-
-
Ghosh, J.C.1
Altieri, D.C.2
-
19
-
-
23344447873
-
Glycogen synthase kinase 3-dependent phosphorylation of Mdm2 regulates p53 abundance
-
Kulikov R, Boehme KA, Blattner C. Glycogen synthase kinase 3-dependent phosphorylation of Mdm2 regulates p53 abundance. Mol Cell Biol 2005, 16:7170-80.
-
(2005)
Mol Cell Biol
, vol.16
, pp. 7170-7180
-
-
Kulikov, R.1
Boehme, K.A.2
Blattner, C.3
-
21
-
-
65349103899
-
Blinded by the light: the growing complexity of p53
-
Vousden KH, Prives C. Blinded by the light: the growing complexity of p53. Cell 2009, 137:413-431.
-
(2009)
Cell
, vol.137
, pp. 413-431
-
-
Vousden, K.H.1
Prives, C.2
-
22
-
-
0842278331
-
Direct activation of Bax by p53 mediates mitochondrial membrane permeabilization and apoptosis
-
Chipuk JE, Kuwana T, Bouchier-Hayes L, Droin NM, Newmeyer DD, Schuler M, Green DR. Direct activation of Bax by p53 mediates mitochondrial membrane permeabilization and apoptosis. Science 2004, 303:1010-14.
-
(2004)
Science
, vol.303
, pp. 1010-1014
-
-
Chipuk, J.E.1
Kuwana, T.2
Bouchier-Hayes, L.3
Droin, N.M.4
Newmeyer, D.D.5
Schuler, M.6
Green, D.R.7
-
23
-
-
65949083750
-
Cytoplasmic functions of the tumour suppressor p53
-
Green DR, Kroemer G. Cytoplasmic functions of the tumour suppressor p53. Nature 2009, 458:1127-30.
-
(2009)
Nature
, vol.458
, pp. 1127-1130
-
-
Green, D.R.1
Kroemer, G.2
-
24
-
-
2342553892
-
Mitochondrial p53 activates Bak and causes disruption of a Bak-Mcl1 complex
-
Leu JI, Dumont P, Hafey M, Murphy ME, George DL. Mitochondrial p53 activates Bak and causes disruption of a Bak-Mcl1 complex. Nat Cell Biol 2004, 5:443-50.
-
(2004)
Nat Cell Biol
, vol.5
, pp. 443-450
-
-
Leu, J.I.1
Dumont, P.2
Hafey, M.3
Murphy, M.E.4
George, D.L.5
-
25
-
-
0037349289
-
P53 has a direct apoptogenic role at the mitochondria
-
Mihara M, Erster S, Zaika A, Petrenko O, Chittenden T, Pancoska P, Moll UM. p53 has a direct apoptogenic role at the mitochondria. Mol Cell 2003, 3:577-90.
-
(2003)
Mol Cell
, vol.3
, pp. 577-590
-
-
Mihara, M.1
Erster, S.2
Zaika, A.3
Petrenko, O.4
Chittenden, T.5
Pancoska, P.6
Moll, U.M.7
-
26
-
-
27544490654
-
Mitochondrially targeted p53 has tumor suppressor activities in vivo
-
Talos F, Petrenko O, Mena P, Moll UM. Mitochondrially targeted p53 has tumor suppressor activities in vivo. Cancer Res 2005, 65:9971-81.
-
(2005)
Cancer Res
, vol.65
, pp. 9971-9981
-
-
Talos, F.1
Petrenko, O.2
Mena, P.3
Moll, U.M.4
-
28
-
-
46749117587
-
P53's mitochondrial translocation and MOMP action is independent of Puma and Bax and severely disrupts mitochondrial membrane integrity
-
Wolff S, Erster S, Palacios G, Moll UM. p53's mitochondrial translocation and MOMP action is independent of Puma and Bax and severely disrupts mitochondrial membrane integrity. Cell Res 2008, 18:733-44.
-
(2008)
Cell Res
, vol.18
, pp. 733-744
-
-
Wolff, S.1
Erster, S.2
Palacios, G.3
Moll, U.M.4
-
29
-
-
77955727322
-
Histone H2AX: The missing link in AIF-mediated caspase-independent programmed necrosis
-
Baritaud M, Boujrad H, Lorenzo HK, Krantic S, Susin SA. Histone H2AX: The missing link in AIF-mediated caspase-independent programmed necrosis. Cell Cycle 2010, 9:3166-73.
-
(2010)
Cell Cycle
, vol.9
, pp. 3166-3173
-
-
Baritaud, M.1
Boujrad, H.2
Lorenzo, H.K.3
Krantic, S.4
Susin, S.A.5
-
30
-
-
18144421236
-
Stress-induced p53 runs a transcription-independent death program
-
Erster S, Moll UM. Stress-induced p53 runs a transcription-independent death program. Biochem Biophys Res Commun 2005, 331:843-50.
-
(2005)
Biochem Biophys Res Commun
, vol.331
, pp. 843-850
-
-
Erster, S.1
Moll, U.M.2
-
31
-
-
77952298503
-
Mitochondrial regulation of cell death: Processing of apoptosis-inducing factor (AIF)
-
Norberg E, Orrenius S, Zhivotovsky B. Mitochondrial regulation of cell death: Processing of apoptosis-inducing factor (AIF). Biochem Biophys Res Comm 2010, 396:95-100.
-
(2010)
Biochem Biophys Res Comm
, vol.396
, pp. 95-100
-
-
Norberg, E.1
Orrenius, S.2
Zhivotovsky, B.3
-
32
-
-
0037317840
-
Inhibiting the p53-MDM2 interaction: an important target for cancer therapy
-
Chène P. Inhibiting the p53-MDM2 interaction: an important target for cancer therapy. Nat Rev Cancer 2003, 2:102-9.
-
(2003)
Nat Rev Cancer
, vol.2
, pp. 102-109
-
-
Chène, P.1
-
33
-
-
33846703114
-
Nutlin3 blocks vascular endothelial growth factor induction by preventing the interaction between hypoxia inducible factor 1 alpha and Hdm2
-
LaRusch GA, Jackson MW, Dunbar JD, Warren RS, Donner DB, Mayo LD. Nutlin3 blocks vascular endothelial growth factor induction by preventing the interaction between hypoxia inducible factor 1 alpha and Hdm2. Cancer Res 2007, 67:450-4.
-
(2007)
Cancer Res
, vol.67
, pp. 450-454
-
-
LaRusch, G.A.1
Jackson, M.W.2
Dunbar, J.D.3
Warren, R.S.4
Donner, D.B.5
Mayo, L.D.6
-
34
-
-
53049108040
-
Targeting the MDM2-p53 interaction for cancer therapy
-
Shangary S, Wang S. Targeting the MDM2-p53 interaction for cancer therapy. Clin Cancer Res 2008, 14:5318-24.
-
(2008)
Clin Cancer Res
, vol.14
, pp. 5318-5324
-
-
Shangary, S.1
Wang, S.2
-
35
-
-
65249100143
-
Small-molecule inhibitors of the MDM2-p53 protein-protein interaction to reactivate p53 function: a novel approach for cancer therapy
-
Shangary S, Wang S. Small-molecule inhibitors of the MDM2-p53 protein-protein interaction to reactivate p53 function: a novel approach for cancer therapy. Annu Rev Pharmacol Toxicol 2009, 49:223-41.
-
(2009)
Annu Rev Pharmacol Toxicol
, vol.49
, pp. 223-241
-
-
Shangary, S.1
Wang, S.2
-
36
-
-
10744221485
-
In vivo activation of the p53 pathway by small-molecule antagonists of MDM2
-
Vassilev LT, Vu BT, Graves B, Carvajal D, Podlaski F, Filipovic Z, Kong N, Kammlott U, Lukacs C, Klein C, Fotouhi N, Liu EA. In vivo activation of the p53 pathway by small-molecule antagonists of MDM2. Science 2004, 303:844-8.
-
(2004)
Science
, vol.303
, pp. 844-848
-
-
Vassilev, L.T.1
Vu, B.T.2
Graves, B.3
Carvajal, D.4
Podlaski, F.5
Filipovic, Z.6
Kong, N.7
Kammlott, U.8
Lukacs, C.9
Klein, C.10
Fotouhi, N.11
Liu, E.A.12
-
37
-
-
60649103811
-
MDM2-dependent downregulation of p21 and hnRNP K provides a switch between apoptosis and growth arrest induced by pharmacologically activated p53
-
Enge M, Bao W, Hedström E, Jackson SP, Moumen A, Selivanova G. MDM2-dependent downregulation of p21 and hnRNP K provides a switch between apoptosis and growth arrest induced by pharmacologically activated p53. Cancer Cell 2009, 15:171-83.
-
(2009)
Cancer Cell
, vol.15
, pp. 171-183
-
-
Enge, M.1
Bao, W.2
Hedström, E.3
Jackson, S.P.4
Moumen, A.5
Selivanova, G.6
-
38
-
-
11144315535
-
Small molecule RITA binds to p53, blocks p53-HDM2 interaction and activates p53 function in tumors
-
Issaeva N, Bozko P, Enge M, Protopopova M, Verhoef LG, Masucci M, Pramanik A, Selivanova G. Small molecule RITA binds to p53, blocks p53-HDM2 interaction and activates p53 function in tumors. Nat Med 2004, 10:1321-7.
-
(2004)
Nat Med
, vol.10
, pp. 1321-1327
-
-
Issaeva, N.1
Bozko, P.2
Enge, M.3
Protopopova, M.4
Verhoef, L.G.5
Masucci, M.6
Pramanik, A.7
Selivanova, G.8
-
39
-
-
0442274617
-
Glycogen synthase kinase-3 beta (GSK3 beta) binds to and promotes the actions of p53
-
Watcharasit P, Bijur GN, Song L, Zhu J, Chen X, Jope RS. Glycogen synthase kinase-3 beta (GSK3 beta) binds to and promotes the actions of p53. J Biol Chem 2003, 278:48872-9.
-
(2003)
J Biol Chem
, vol.278
, pp. 48872-48879
-
-
Watcharasit, P.1
Bijur, G.N.2
Song, L.3
Zhu, J.4
Chen, X.5
Jope, R.S.6
-
40
-
-
38149102519
-
GSK-3β inhibition enhances sorafenib-induced apoptosis in melanoma cell lines
-
Panka DJ, Cho DC, Atkins MB, Mier JW. GSK-3β inhibition enhances sorafenib-induced apoptosis in melanoma cell lines. J Biol Chem 2008, 283:726-32.
-
(2008)
J Biol Chem
, vol.283
, pp. 726-732
-
-
Panka, D.J.1
Cho, D.C.2
Atkins, M.B.3
Mier, J.W.4
-
41
-
-
33747620737
-
Small-molecule inhibitor of p53 binding to mitochondria protects mice from gamma radiation
-
Strom E, Sathe S, Komarov PG, Chernova OB, Pavlovska I, Shyshynova I, Bosykh DA, Burdelya LG, Macklis RM, Skaliter R, Komarova EA, Gudkov AV. Small-molecule inhibitor of p53 binding to mitochondria protects mice from gamma radiation. Nature Chem Biol 2006, 2:4749.
-
(2006)
Nature Chem Biol
, vol.2
, pp. 4749
-
-
Strom, E.1
Sathe, S.2
Komarov, P.G.3
Chernova, O.B.4
Pavlovska, I.5
Shyshynova, I.6
Bosykh, D.A.7
Burdelya, L.G.8
Macklis, R.M.9
Skaliter, R.10
Komarova, E.A.11
Gudkov, A.V.12
-
42
-
-
67649909568
-
Results of a phase III, randomized, placebo-controlled study of sorafenib in combination with carboplatinum and paclitaxel as second-line treatment in patients with unresectable stage III or stage IV melanoma
-
Hauschild A, Agarwala SS, Trefzer U, Hogg D, Robert C, Hersey P, Eggermont A, Grabbe S, Gonzalez R, Gille J, Peschel C, Schadendorf D, Garbe C, O'Day S, Daud A, White JM, Xia C, Patel K, Kirkwood JM, Keilholz U. Results of a phase III, randomized, placebo-controlled study of sorafenib in combination with carboplatinum and paclitaxel as second-line treatment in patients with unresectable stage III or stage IV melanoma. J Clin Oncol 2009, 27:2823-30.
-
(2009)
J Clin Oncol
, vol.27
, pp. 2823-2830
-
-
Hauschild, A.1
Agarwala, S.S.2
Trefzer, U.3
Hogg, D.4
Robert, C.5
Hersey, P.6
Eggermont, A.7
Grabbe, S.8
Gonzalez, R.9
Gille, J.10
Peschel, C.11
Schadendorf, D.12
Garbe, C.13
O'Day, S.14
Daud, A.15
White, J.M.16
Xia, C.17
Patel, K.18
Kirkwood, J.M.19
Keilholz, U.20
more..
-
43
-
-
43749110700
-
Double-blind randomized phase II study of the combination of sorafenib and dacarbazine in patients with advanced melanoma: a report from the 11715 Study Group
-
McDermott DF, Sosman JA, Gonzalez R, Hodi FS, Linette GP, Richards J, Jakub JW, Beeram M, Tarantolo S, Agarwala S, Frenette G, Puzanov I, Cranmer L, Lewis K, Kirkwood J, White JM, Xia C, Patel K, Hersh E. Double-blind randomized phase II study of the combination of sorafenib and dacarbazine in patients with advanced melanoma: a report from the 11715 Study Group. J Clin Oncol 2008, 26:2178-85.
-
(2008)
J Clin Oncol
, vol.26
, pp. 2178-2185
-
-
McDermott, D.F.1
Sosman, J.A.2
Gonzalez, R.3
Hodi, F.S.4
Linette, G.P.5
Richards, J.6
Jakub, J.W.7
Beeram, M.8
Tarantolo, S.9
Agarwala, S.10
Frenette, G.11
Puzanov, I.12
Cranmer, L.13
Lewis, K.14
Kirkwood, J.15
White, J.M.16
Xia, C.17
Patel, K.18
Hersh, E.19
-
44
-
-
79551492981
-
Nucleoside analogs induce proteasomal down-regulation of p21 in chronic lymphocytic leukemia cell lines
-
Bastin-Coyette L, Cardoen S, Smal C, de Viron E, Arts A, Amsailale R, Van Den Neste E, Bontemps F. Nucleoside analogs induce proteasomal down-regulation of p21 in chronic lymphocytic leukemia cell lines. Biochem Pharmacol 2011, 81:586-93.
-
(2011)
Biochem Pharmacol
, vol.81
, pp. 586-593
-
-
Bastin-Coyette, L.1
Cardoen, S.2
Smal, C.3
de Viron, E.4
Arts, A.5
Amsailale, R.6
Van Den Neste, E.7
Bontemps, F.8
-
45
-
-
78149486374
-
CRL2 (LRR-1) targets a CDK inhibitor for cell cycle control in C. elegans and actin-based motility regulation in human cells
-
Starostina NG, Simpliciano JM, McGuirk MA, Kipreos ET. CRL2 (LRR-1) targets a CDK inhibitor for cell cycle control in C. elegans and actin-based motility regulation in human cells. Dev Cell 2010, 19:753-64.
-
(2010)
Dev Cell
, vol.19
, pp. 753-764
-
-
Starostina, N.G.1
Simpliciano, J.M.2
McGuirk, M.A.3
Kipreos, E.T.4
-
46
-
-
32944479041
-
The raf inhibitor BAY 43-9006 (sorafenib) induces caspase-independent apoptosis in melanoma cells
-
Panka DJ, Wang W, Atkins MB, Mier JW. The raf inhibitor BAY 43-9006 (sorafenib) induces caspase-independent apoptosis in melanoma cells. Cancer Res 2006, 66:1611-9.
-
(2006)
Cancer Res
, vol.66
, pp. 1611-1619
-
-
Panka, D.J.1
Wang, W.2
Atkins, M.B.3
Mier, J.W.4
-
47
-
-
76049095102
-
Oxidative modification sensitizes mitochondrial apoptosis-inducing factor to calpain-mediated processing
-
Norberg E, Gogvadze V, Vakifahmetoglu H, Orrenius S, Zhivotovsky B. Oxidative modification sensitizes mitochondrial apoptosis-inducing factor to calpain-mediated processing. Free Rad Biol Med 2010, 48:791-7.
-
(2010)
Free Rad Biol Med
, vol.48
, pp. 791-797
-
-
Norberg, E.1
Gogvadze, V.2
Vakifahmetoglu, H.3
Orrenius, S.4
Zhivotovsky, B.5
-
48
-
-
67449128222
-
Direct interaction between Nrf2 and p21 (Cip/WAF1) upregulates the Nrf2-mediated antioxidant response
-
Chen W, Sun Z, Wang XJ, Jiang T, Huang Z, Fang D, Zhang D. Direct interaction between Nrf2 and p21 (Cip/WAF1) upregulates the Nrf2-mediated antioxidant response. Mol Cell 2009, 34:663-73.
-
(2009)
Mol Cell
, vol.34
, pp. 663-673
-
-
Chen, W.1
Sun, Z.2
Wang, X.J.3
Jiang, T.4
Huang, Z.5
Fang, D.6
Zhang, D.7
-
49
-
-
17844366846
-
WNTs in the vertebrate nervous system: from patterning to neuronal connectivity
-
Ciani L, Salinas PC. WNTs in the vertebrate nervous system: from patterning to neuronal connectivity. Nat Rev Neurosci 2005, 6:531-62.
-
(2005)
Nat Rev Neurosci
, vol.6
, pp. 531-562
-
-
Ciani, L.1
Salinas, P.C.2
-
50
-
-
0032483439
-
Identification of c-myc as a target of the APC pathway
-
He TC, Sparks AB, Rago C, Hermeking H, Zawel L, da Costa LT, Morin PJ, Vogelstein B, Kinzler KW. Identification of c-myc as a target of the APC pathway. Science 1998, 281:1509-12.
-
(1998)
Science
, vol.281
, pp. 1509-1512
-
-
He, T.C.1
Sparks, A.B.2
Rago, C.3
Hermeking, H.4
Zawel, L.5
da Costa, L.T.6
Morin, P.J.7
Vogelstein, B.8
Kinzler, K.W.9
-
51
-
-
33646345376
-
Ubiquitin ligases: cell cycle control and cancer
-
Nakayama KI, Nakayama K. Ubiquitin ligases: cell cycle control and cancer. Nat Rev Cancer 2006, 6:369-381.
-
(2006)
Nat Rev Cancer
, vol.6
, pp. 369-381
-
-
Nakayama, K.I.1
Nakayama, K.2
-
52
-
-
0034808019
-
Down-regulation of beta-catenin by activated p53
-
Sadot E, Geiger B, Oren M, Ben-Ze'ev A. Down-regulation of beta-catenin by activated p53. Mol Cell Biol 2001, 21:6768-80.
-
(2001)
Mol Cell Biol
, vol.21
, pp. 6768-6780
-
-
Sadot, E.1
Geiger, B.2
Oren, M.3
Ben-Ze'ev, A.4
-
53
-
-
38549086019
-
FBW7 ubiquitin ligase: a tumor suppressor at the crossroads of cell division and differentiation
-
Welcker M, Clurman BE. FBW7 ubiquitin ligase: a tumor suppressor at the crossroads of cell division and differentiation. Nature Rev Cancer 2008, 8:83-97.
-
(2008)
Nature Rev Cancer
, vol.8
, pp. 83-97
-
-
Welcker, M.1
Clurman, B.E.2
-
54
-
-
77957585949
-
An inexpensive, specific and highly sensitive protocol to detect the BRAFV600E mutation in melanoma tumor biopsies and blood
-
Panka DJ, Sullivan RJ, Mier JW. An inexpensive, specific and highly sensitive protocol to detect the BRAFV600E mutation in melanoma tumor biopsies and blood. Melanoma Res 2010, 20:401-7.
-
(2010)
Melanoma Res
, vol.20
, pp. 401-407
-
-
Panka, D.J.1
Sullivan, R.J.2
Mier, J.W.3
-
55
-
-
0026651787
-
Rapid evolution of the human gene for cytochrome c oxidase subunit IV
-
Lomax MI, Hewett-Emmett D, Yang TL, Grossman LI. Rapid evolution of the human gene for cytochrome c oxidase subunit IV. Proc Natl Acad Sci USA 1992, 89:5266-5270.
-
(1992)
Proc Natl Acad Sci USA
, vol.89
, pp. 5266-5270
-
-
Lomax, M.I.1
Hewett-Emmett, D.2
Yang, T.L.3
Grossman, L.I.4
-
56
-
-
0023079956
-
Isolation and analysis of nuclear RNA
-
Academic Press
-
Nevins JR. Isolation and analysis of nuclear RNA. Meth Enzymol 1987, 152:234-236. Academic Press.
-
(1987)
Meth Enzymol
, vol.152
, pp. 234-236
-
-
Nevins, J.R.1
-
57
-
-
67049132896
-
Does arterial spin-labeling MR imaging-measured tumor perfusion correlate with renal cell cancer response to antiangiogenic therapy in a mouse model?
-
Schor-Bardach R, Alsop DC, Pedrosa I, Solazzo SA, Wang X, Marquis RP, Atkins MB, Regan M, Signoretti S, Lenkinski RE, Goldberg SN. Does arterial spin-labeling MR imaging-measured tumor perfusion correlate with renal cell cancer response to antiangiogenic therapy in a mouse model?. Radiology 2009, 251:731-742.
-
(2009)
Radiology
, vol.251
, pp. 731-742
-
-
Schor-Bardach, R.1
Alsop, D.C.2
Pedrosa, I.3
Solazzo, S.A.4
Wang, X.5
Marquis, R.P.6
Atkins, M.B.7
Regan, M.8
Signoretti, S.9
Lenkinski, R.E.10
Goldberg, S.N.11
-
58
-
-
46849093651
-
Perfusion MDCT enables early detection of therapeutic response to antiangiogenic therapy
-
Sabir A, Schor-Bardach R, Wilcox CJ, Rahmanuddin S, Atkins MB, Kruskal JB, Signoretti S, Raptopoulos VD, Goldberg SN. Perfusion MDCT enables early detection of therapeutic response to antiangiogenic therapy. AJR Am J Roentgenol 2008, 191:133-9.
-
(2008)
AJR Am J Roentgenol
, vol.191
, pp. 133-139
-
-
Sabir, A.1
Schor-Bardach, R.2
Wilcox, C.J.3
Rahmanuddin, S.4
Atkins, M.B.5
Kruskal, J.B.6
Signoretti, S.7
Raptopoulos, V.D.8
Goldberg, S.N.9
-
59
-
-
72549094296
-
An MDM2 antagonist (MI-319) restores p53 functions and increases the life span of orally treated follicular lymphoma bearing animals
-
Mohammad RM, Wu J, Azmi AS, Aboukameel A, Sosin A, Wu S, Yang D, Wang S, Al-Katib AM. An MDM2 antagonist (MI-319) restores p53 functions and increases the life span of orally treated follicular lymphoma bearing animals. Mol Cancer 2009, 8:115-128.
-
(2009)
Mol Cancer
, vol.8
, pp. 115-128
-
-
Mohammad, R.M.1
Wu, J.2
Azmi, A.S.3
Aboukameel, A.4
Sosin, A.5
Wu, S.6
Yang, D.7
Wang, S.8
Al-Katib, A.M.9
-
60
-
-
77949659052
-
MDM2 inhibitor MI-319 in combination with cisplatin is an effective treatment for pancreatic cancer independent of p53 function
-
Azmi AS, Aboukameel A, Banerjee S, Wang Z, Mohammad M, Wu J, Wang S, Yang D, Philip PA, Sarkar FH, Mohammad RM. MDM2 inhibitor MI-319 in combination with cisplatin is an effective treatment for pancreatic cancer independent of p53 function. Eur J Cancer 2010, 46:1122-31.
-
(2010)
Eur J Cancer
, vol.46
, pp. 1122-1131
-
-
Azmi, A.S.1
Aboukameel, A.2
Banerjee, S.3
Wang, Z.4
Mohammad, M.5
Wu, J.6
Wang, S.7
Yang, D.8
Philip, P.A.9
Sarkar, F.H.10
Mohammad, R.M.11
-
61
-
-
78649467980
-
Role of transcription factors in small intestinal ischemia-reperfusion injury and tolerance induced by ischemic preconditioning
-
Takeshita M, Tani T, Harada S, Hayashi H, Itoh H, Tajima H, Ohnishi I, Takamura H, Fushida S, Kayahara M. Role of transcription factors in small intestinal ischemia-reperfusion injury and tolerance induced by ischemic preconditioning. Transplant Proc 2010, 42:3406-13.
-
(2010)
Transplant Proc
, vol.42
, pp. 3406-3413
-
-
Takeshita, M.1
Tani, T.2
Harada, S.3
Hayashi, H.4
Itoh, H.5
Tajima, H.6
Ohnishi, I.7
Takamura, H.8
Fushida, S.9
Kayahara, M.10
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